Click here to switch to the map view.

The map label for this gene is aspB-2

Identifier: 15897783

GI number: 15897783

Start: 762340

End: 763548

Strand: Direct

Name: aspB-2

Synonym: SSO0897

Alternate gene names: 15897783

Gene position: 762340-763548 (Clockwise)

Preceding gene: 15897782

Following gene: 15897785

Centisome position: 25.48

GC content: 35.73

Gene sequence:

>1209_bases
GTGGTCTCGCTACTAGACTTTAACGGAAATATGTCACAAGTTACTGGAGAGACTACCTTATTGTATAAGGAAATTGCTAG
AAACGTAGAAAAGACTAAGAAGATTAAAATTATCGACTTTGGGATAGGACAACCAGATTTACCTACATTTAAACGTATAA
GAGATGCCGCAAAGGAGGCGCTAGATCAAGGTTTTACTTTCTACACTTCGGCATTCGGTATTGATGAATTAAGGGAAAAA
ATAGCTCAATACCTAAATACTAGATACGGTACTGACGTAAAGAAGGAGGAAGTGATAGTAACACCTGGTGCTAAGCCTGC
GCTTTTCTTAGTCTTTATATTATATATTAATCCAAGTGACGAGGTAATACTCCCAGATCCCTCCTTCTATTCTTACGCTG
AGGTTGTTAAGTTACTAGGAGGAAAGCCAATATATGCCAATTTAAAGTGGAGCAGAGAAGAAGGGTTCTCAATAGATGTA
GACGACCTACAATCTAAAATATCGAAAAGAACCAAAATGATAGTATTCAATAATCCTCATAATCCGACTGGTACTCTATT
CTCTCCTAATGATGTTAAGAAAATTGTGGATATAAGTAGGGATAATAAAATTATCTTACTATCTGACGAGATTTATGATA
ATTTTGTATATGAAGGTAAGATGAGAAGTACTCTTGAAGACTCAGATTGGAGAGATTTCTTAATTTACGTTAATGGATTT
AGTAAAACTTTCTCGATGACTGGATGGAGATTAGGTTATATTGTAGCGAAGCGTGAAATTATCCAGAAAATGGGAATTTT
GGCTGCTAACGTATACACTGCTCCTACAAGTTTTGTACAAAAAGCCGCAGTAAAGGCCTTTGATACTTTCGACGAAGTTA
ACCAAATGGTCAGCCTATTTAAGAAGAGGAGAGACGTAATGTATGATGAACTTACTAAGGTCAAAGGAGTTGAAGTATCT
AAACCAAATGGAGCATTCTATATGTTCCCAAATGTTAGTAAGATACTTAAAACAAGTGGATTTGACGTCAAGTCACTTGC
CATAAAGCTAATTGAAGAAAAAGGCGTAGTTACAATACCTGGTGAAGTTTTCCCATTAAATATAGGTAAGGAGTTTTTAA
GATTAAGTTTTGCTGTGAACGAAGAAGTTATTAAAGAGGGCATACAAAAAATTAGAGAGTTCGCGGAACAGATGATGAAT
TCCCGATAG

Upstream 100 bases:

>100_bases
AAGGAAATTAGGTGTTAACGCTTTCCTAATCGGATCATCACTGATGCGAAACCCAGAAAAGATTAAAGAATTTATACTAT
AGCGTTCTTCATATACACTT

Downstream 100 bases:

>100_bases
TACGATTGATGAGCTAAACTCCCATGGACTGATTAGCAGTTTTAATTTCCACTTTTTCTTCATTCGATTCTATTAGTTCA
AGATTAGTTACCTTTAATGT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MVSLLDFNGNMSQVTGETTLLYKEIARNVEKTKKIKIIDFGIGQPDLPTFKRIRDAAKEALDQGFTFYTSAFGIDELREK
IAQYLNTRYGTDVKKEEVIVTPGAKPALFLVFILYINPSDEVILPDPSFYSYAEVVKLLGGKPIYANLKWSREEGFSIDV
DDLQSKISKRTKMIVFNNPHNPTGTLFSPNDVKKIVDISRDNKIILLSDEIYDNFVYEGKMRSTLEDSDWRDFLIYVNGF
SKTFSMTGWRLGYIVAKREIIQKMGILAANVYTAPTSFVQKAAVKAFDTFDEVNQMVSLFKKRRDVMYDELTKVKGVEVS
KPNGAFYMFPNVSKILKTSGFDVKSLAIKLIEEKGVVTIPGEVFPLNIGKEFLRLSFAVNEEVIKEGIQKIREFAEQMMN
SR

Sequences:

>Translated_402_residues
MVSLLDFNGNMSQVTGETTLLYKEIARNVEKTKKIKIIDFGIGQPDLPTFKRIRDAAKEALDQGFTFYTSAFGIDELREK
IAQYLNTRYGTDVKKEEVIVTPGAKPALFLVFILYINPSDEVILPDPSFYSYAEVVKLLGGKPIYANLKWSREEGFSIDV
DDLQSKISKRTKMIVFNNPHNPTGTLFSPNDVKKIVDISRDNKIILLSDEIYDNFVYEGKMRSTLEDSDWRDFLIYVNGF
SKTFSMTGWRLGYIVAKREIIQKMGILAANVYTAPTSFVQKAAVKAFDTFDEVNQMVSLFKKRRDVMYDELTKVKGVEVS
KPNGAFYMFPNVSKILKTSGFDVKSLAIKLIEEKGVVTIPGEVFPLNIGKEFLRLSFAVNEEVIKEGIQKIREFAEQMMN
SR
>Mature_402_residues
MVSLLDFNGNMSQVTGETTLLYKEIARNVEKTKKIKIIDFGIGQPDLPTFKRIRDAAKEALDQGFTFYTSAFGIDELREK
IAQYLNTRYGTDVKKEEVIVTPGAKPALFLVFILYINPSDEVILPDPSFYSYAEVVKLLGGKPIYANLKWSREEGFSIDV
DDLQSKISKRTKMIVFNNPHNPTGTLFSPNDVKKIVDISRDNKIILLSDEIYDNFVYEGKMRSTLEDSDWRDFLIYVNGF
SKTFSMTGWRLGYIVAKREIIQKMGILAANVYTAPTSFVQKAAVKAFDTFDEVNQMVSLFKKRRDVMYDELTKVKGVEVS
KPNGAFYMFPNVSKILKTSGFDVKSLAIKLIEEKGVVTIPGEVFPLNIGKEFLRLSFAVNEEVIKEGIQKIREFAEQMMN
SR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family

Homologues:

Organism=Homo sapiens, GI4507369, Length=378, Percent_Identity=25.9259259259259, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI95147551, Length=408, Percent_Identity=25.2450980392157, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI169881279, Length=408, Percent_Identity=25.2450980392157, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI56713254, Length=397, Percent_Identity=25.9445843828715, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI56713256, Length=397, Percent_Identity=25.9445843828715, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI169881281, Length=305, Percent_Identity=24.9180327868852, Blast_Score=102, Evalue=5e-22,
Organism=Escherichia coli, GI1786816, Length=373, Percent_Identity=26.8096514745308, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1788627, Length=333, Percent_Identity=27.3273273273273, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788722, Length=370, Percent_Identity=25.1351351351351, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788332, Length=212, Percent_Identity=25.4716981132075, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787710, Length=301, Percent_Identity=19.9335548172757, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17567369, Length=380, Percent_Identity=30, Blast_Score=147, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI71994472, Length=264, Percent_Identity=30.3030303030303, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71994476, Length=264, Percent_Identity=30.3030303030303, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17567663, Length=385, Percent_Identity=27.2727272727273, Blast_Score=125, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6322401, Length=386, Percent_Identity=23.8341968911917, Blast_Score=112, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6323118, Length=372, Percent_Identity=25.5376344086022, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320317, Length=353, Percent_Identity=22.6628895184136, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573069, Length=398, Percent_Identity=25.3768844221106, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24646114, Length=398, Percent_Identity=25.3768844221106, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28573067, Length=398, Percent_Identity=25.3768844221106, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28573065, Length=398, Percent_Identity=25.3768844221106, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI18859735, Length=397, Percent_Identity=24.4332493702771, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI45551451, Length=400, Percent_Identity=23.5, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24641770, Length=400, Percent_Identity=23.5, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24641760, Length=400, Percent_Identity=23.5, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24641768, Length=400, Percent_Identity=23.5, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24641766, Length=400, Percent_Identity=23.5, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24641764, Length=400, Percent_Identity=23.5, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356535, Length=389, Percent_Identity=23.1362467866324, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AAT_SULSO (P14909)

Other databases:

- EMBL:   X16505
- EMBL:   AE006641
- PIR:   S07088
- RefSeq:   NP_342388.1
- ProteinModelPortal:   P14909
- SMR:   P14909
- GeneID:   1455145
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO0897
- NMPDR:   fig|273057.1.peg.811
- HOGENOM:   HBG645860
- OMA:   IIPDPSY
- PhylomeDB:   P14909
- ProtClustDB:   PRK05764
- BioCyc:   MetaCyc:MONOMER-13008
- BioCyc:   SSOL273057:SSO0897-MONOMER
- BRENDA:   2.6.1.1
- GO:   GO:0005737
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10

Pfam domain/function: PF00155 Aminotran_1_2; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.1

Molecular weight: Translated: 45732; Mature: 45732

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: BINDING 43-43 BINDING 181-181 BINDING 374-374

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLLDFNGNMSQVTGETTLLYKEIARNVEKTKKIKIIDFGIGQPDLPTFKRIRDAAKEA
CEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHH
LDQGFTFYTSAFGIDELREKIAQYLNTRYGTDVKKEEVIVTPGAKPALFLVFILYINPSD
HHCCCEEEHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHEEEEEEEEECCCC
EVILPDPSFYSYAEVVKLLGGKPIYANLKWSREEGFSIDVDDLQSKISKRTKMIVFNNPH
CEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEECHHHHHHHHHHCEEEEEEECCC
NPTGTLFSPNDVKKIVDISRDNKIILLSDEIYDNFVYEGKMRSTLEDSDWRDFLIYVNGF
CCCCCCCCCHHHHHHHHCCCCCEEEEEEHHHHHHHEECCCHHCCCCCCCCCEEEEEEECC
SKTFSMTGWRLGYIVAKREIIQKMGILAANVYTAPTSFVQKAAVKAFDTFDEVNQMVSLF
CCHHCCCCCHHHHHHHHHHHHHHHHHHHEEHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KKRRDVMYDELTKVKGVEVSKPNGAFYMFPNVSKILKTSGFDVKSLAIKLIEEKGVVTIP
HHHHHHHHHHHHHHCCCEEECCCCCEEECCCHHHHHHCCCCCHHHHHHHHHHCCCEEECC
GEVFPLNIGKEFLRLSFAVNEEVIKEGIQKIREFAEQMMNSR
CCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVSLLDFNGNMSQVTGETTLLYKEIARNVEKTKKIKIIDFGIGQPDLPTFKRIRDAAKEA
CEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHH
LDQGFTFYTSAFGIDELREKIAQYLNTRYGTDVKKEEVIVTPGAKPALFLVFILYINPSD
HHCCCEEEHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHEEEEEEEEECCCC
EVILPDPSFYSYAEVVKLLGGKPIYANLKWSREEGFSIDVDDLQSKISKRTKMIVFNNPH
CEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEECHHHHHHHHHHCEEEEEEECCC
NPTGTLFSPNDVKKIVDISRDNKIILLSDEIYDNFVYEGKMRSTLEDSDWRDFLIYVNGF
CCCCCCCCCHHHHHHHHCCCCCEEEEEEHHHHHHHEECCCHHCCCCCCCCCEEEEEEECC
SKTFSMTGWRLGYIVAKREIIQKMGILAANVYTAPTSFVQKAAVKAFDTFDEVNQMVSLF
CCHHCCCCCHHHHHHHHHHHHHHHHHHHEEHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KKRRDVMYDELTKVKGVEVSKPNGAFYMFPNVSKILKTSGFDVKSLAIKLIEEKGVVTIP
HHHHHHHHHHHHHHCCCEEECCCCCEEECCCHHHHHHCCCCCHHHHHHHHHHCCCEEECC
GEVFPLNIGKEFLRLSFAVNEEVIKEGIQKIREFAEQMMNSR
CCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2513189; 11427726; 8026489; 3137225; 1954227