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The map label for this gene is galE-2 [C]

Identifier: 15897713

GI number: 15897713

Start: 695680

End: 696612

Strand: Direct

Name: galE-2 [C]

Synonym: SSO0809

Alternate gene names: 15897713

Gene position: 695680-696612 (Clockwise)

Preceding gene: 15897711

Following gene: 15897714

Centisome position: 23.25

GC content: 35.69

Gene sequence:

>933_bases
TTGTTGATGAAAATACTTATAAGTGGAGGAGCGGGATTCTTAGGTTCTCATCTAACAGAGGCATTGTTAGAAAAAGGAGA
GGAAATAACAATAGTTGATGATCTATCAACCGCAAAATACTTTAATATACGAAAAGATGTAGAATTTATTAAGAAAAAAG
TTGAGGAATTTGAGACAGAAAAAAAGTACGACGTCGTCATCCATTTGGCAGCTAGACCTTCACCGGAGGACTACATAGAA
CATCCAGTAGATACAGCTCTTTCTAATTCACTAGGTACTTACAAAATGCTCGAAATAGCCAGAAAAAGTAATGCAAGATT
TATATACACATCTTCATCTGAAGTATATGGTTCTGCCTCAATAATTCCGACCCCTGAAACGTATTGGGGTTACGTAAATC
CTATAGGAATAAGGAGCTGTTATGACGAAAGCAAGAGATTCTCAGAAGCTTTGATAATGGCTTACCACAGACAATATAAG
TTAGATACAAGAATCCAGAGGCCTTTTAATGTATATGGCCCTGGTCTAAGAGAAGATGGAACTTATGGTAGAGTGGTTTC
AAGATTTATTTATCAAGCACTAAAAGGAGAGGACGTAACAGTGTTCGGAGATGGGAATCAAACTAGAGCTTTTCTATATA
TATCTGACTGGGTTGATGCTACAATAAAATTAATATACAAAGATGGACTAGAAGGTGAAGTATTTAATATAGGTTCAGAC
AAAGAAATAAAGATTATTGAGTTGGCTAATATGATAATTAAGCTTACCGGTAGCAAATCTAGAATTAAATATCTTCCCCC
TAGACCAGATGACCCACCTAGGAGAGCAGCTGACATAACTAAGGCTAAGGAAAAATTGGGCTGGTATCCTAAAATTTCCT
TAGAAGAGGGATTAAAACTTACCATAAATTGGTTTAAGGGTGTATTAAAATGA

Upstream 100 bases:

>100_bases
GAAAAATTTATAAATGCATGACACTATTTATAATTATATACGTATACTTTTCTCTAATAATTTTGTAACCAAAAGATTTA
TATCTCGTCAAAGATAGAGA

Downstream 100 bases:

>100_bases
GAATAGGTGTTGTAGGATTAGGTGTTGTAGGATTAGTAACGGGGGCAGTATTAGCAGATCAAGGACATGAAGTAGTTGGA
GTAGACATTGATCAAAATAA

Product: UDP-glucose 4-epimerase (galE-2)

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MLMKILISGGAGFLGSHLTEALLEKGEEITIVDDLSTAKYFNIRKDVEFIKKKVEEFETEKKYDVVIHLAARPSPEDYIE
HPVDTALSNSLGTYKMLEIARKSNARFIYTSSSEVYGSASIIPTPETYWGYVNPIGIRSCYDESKRFSEALIMAYHRQYK
LDTRIQRPFNVYGPGLREDGTYGRVVSRFIYQALKGEDVTVFGDGNQTRAFLYISDWVDATIKLIYKDGLEGEVFNIGSD
KEIKIIELANMIIKLTGSKSRIKYLPPRPDDPPRRAADITKAKEKLGWYPKISLEEGLKLTINWFKGVLK

Sequences:

>Translated_310_residues
MLMKILISGGAGFLGSHLTEALLEKGEEITIVDDLSTAKYFNIRKDVEFIKKKVEEFETEKKYDVVIHLAARPSPEDYIE
HPVDTALSNSLGTYKMLEIARKSNARFIYTSSSEVYGSASIIPTPETYWGYVNPIGIRSCYDESKRFSEALIMAYHRQYK
LDTRIQRPFNVYGPGLREDGTYGRVVSRFIYQALKGEDVTVFGDGNQTRAFLYISDWVDATIKLIYKDGLEGEVFNIGSD
KEIKIIELANMIIKLTGSKSRIKYLPPRPDDPPRRAADITKAKEKLGWYPKISLEEGLKLTINWFKGVLK
>Mature_310_residues
MLMKILISGGAGFLGSHLTEALLEKGEEITIVDDLSTAKYFNIRKDVEFIKKKVEEFETEKKYDVVIHLAARPSPEDYIE
HPVDTALSNSLGTYKMLEIARKSNARFIYTSSSEVYGSASIIPTPETYWGYVNPIGIRSCYDESKRFSEALIMAYHRQYK
LDTRIQRPFNVYGPGLREDGTYGRVVSRFIYQALKGEDVTVFGDGNQTRAFLYISDWVDATIKLIYKDGLEGEVFNIGSD
KEIKIIELANMIIKLTGSKSRIKYLPPRPDDPPRRAADITKAKEKLGWYPKISLEEGLKLTINWFKGVLK

Specific function: INVOLVED IN THE SYNTHESIS OF ENTEROBACTERIAL COMMON ANTIGEN (ECA) AND REQUIRED FOR SYNTHESIS OF LIPOPOLYSACCHARIDE O-SIDE CHAINS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=312, Percent_Identity=43.2692307692308, Blast_Score=261, Evalue=5e-70,
Organism=Homo sapiens, GI7657641, Length=326, Percent_Identity=30.0613496932515, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI56237023, Length=346, Percent_Identity=25.4335260115607, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI56118217, Length=346, Percent_Identity=25.4335260115607, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI189083684, Length=346, Percent_Identity=25.4335260115607, Blast_Score=90, Evalue=2e-18,
Organism=Escherichia coli, GI48994969, Length=339, Percent_Identity=30.0884955752212, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1788353, Length=342, Percent_Identity=28.9473684210526, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=25.5952380952381, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788365, Length=322, Percent_Identity=27.639751552795, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788589, Length=335, Percent_Identity=28.0597014925373, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17539532, Length=309, Percent_Identity=40.1294498381877, Blast_Score=237, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI17568069, Length=328, Percent_Identity=29.5731707317073, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI115532424, Length=332, Percent_Identity=27.710843373494, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71982035, Length=343, Percent_Identity=25.9475218658892, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71982038, Length=345, Percent_Identity=25.7971014492754, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17507723, Length=341, Percent_Identity=22.5806451612903, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6319493, Length=340, Percent_Identity=26.1764705882353, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21356223, Length=312, Percent_Identity=44.2307692307692, Blast_Score=257, Evalue=8e-69,
Organism=Drosophila melanogaster, GI19923002, Length=340, Percent_Identity=25, Blast_Score=84, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35279; Mature: 35279

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMKILISGGAGFLGSHLTEALLEKGEEITIVDDLSTAKYFNIRKDVEFIKKKVEEFETE
CEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
KKYDVVIHLAARPSPEDYIEHPVDTALSNSLGTYKMLEIARKSNARFIYTSSSEVYGSAS
CCEEEEEEEECCCCHHHHHCCCHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEE
IIPTPETYWGYVNPIGIRSCYDESKRFSEALIMAYHRQYKLDTRIQRPFNVYGPGLREDG
ECCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCC
TYGRVVSRFIYQALKGEDVTVFGDGNQTRAFLYISDWVDATIKLIYKDGLEGEVFNIGSD
CHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEECHHHHEEEEEEECCCCCEEEECCCC
KEIKIIELANMIIKLTGSKSRIKYLPPRPDDPPRRAADITKAKEKLGWYPKISLEEGLKL
CCEEHEEEECCCEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCEE
TINWFKGVLK
EEHHHHHHCC
>Mature Secondary Structure
MLMKILISGGAGFLGSHLTEALLEKGEEITIVDDLSTAKYFNIRKDVEFIKKKVEEFETE
CEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
KKYDVVIHLAARPSPEDYIEHPVDTALSNSLGTYKMLEIARKSNARFIYTSSSEVYGSAS
CCEEEEEEEECCCCHHHHHCCCHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEE
IIPTPETYWGYVNPIGIRSCYDESKRFSEALIMAYHRQYKLDTRIQRPFNVYGPGLREDG
ECCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCC
TYGRVVSRFIYQALKGEDVTVFGDGNQTRAFLYISDWVDATIKLIYKDGLEGEVFNIGSD
CHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEECHHHHEEEEEEECCCCCEEEECCCC
KEIKIIELANMIIKLTGSKSRIKYLPPRPDDPPRRAADITKAKEKLGWYPKISLEEGLKL
CCEEHEEEECCCEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCEE
TINWFKGVLK
EEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]