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The map label for this gene is ksgA [H]

Identifier: 15897649

GI number: 15897649

Start: 635111

End: 635695

Strand: Reverse

Name: ksgA [H]

Synonym: SSO0749

Alternate gene names: 15897649

Gene position: 635695-635111 (Counterclockwise)

Preceding gene: 15897650

Following gene: 15897648

Centisome position: 21.24

GC content: 30.77

Gene sequence:

>585_bases
GTGGATAATGGGATTAGGCCCATTTTAGAGATTGGCTGTGGAAAGGGAAATATTACAAGGTTTTTAGAACCGGATATTTG
TATCGAATTGGATGATAAAATGATAGAGTATTTGAAAAACTTCAATCTTGTAATAGCTGATGCAAGATATTTACCAGTAT
TAAGGGGACAATTAGTTTCTTCTCTACCTTATCAGATAACTTCAGATTTTTTCAAAGAAGTGATTAAACTTAATAATATA
CGTAAACTTACATTAATTTTGCAAAAAGATTTTGTAGATAAGATTTTTAACGATTCTACCTATATTTCTTTTTTGCTTAA
CTACATTTATAATATACAAATCAAAGACATAATTCCGCCAAGTTGTTTCAGTCCTCGTCCGAAAGTCTATTCGATTATTA
CAATTTTTAATAGGATAAGAGAATATGATAAGGAGGTTGATAGCATACTTTCGTGTATTAGTAGATATAGGAATAAAACC
CTAAGAAAGGCCTCCAAGTTGTGTGGTTTTAGTTCTAATAACGACTTAAAGGTGAGGGAATTTAAACCTTGGCAAGTGTT
AGAATTATTGAATTCCGTGGGATAA

Upstream 100 bases:

>100_bases
AGCAGCAATTCATTTATGTGGGCTATATTGAAAAGCTAAAGTAAGGCTTTCACAAGTTTTTCTTATTGATGAGAATTTTA
TACGGAAGTTTATTTCATAT

Downstream 100 bases:

>100_bases
GATTATGTTTAAATGATCAGACATACGAACCTTCTGACGATACTGATATTCTCCTTAGCTTACTCAGAGTAGGTAAAGGA
GATAAGGTCTTAGATATGGG

Product: dimethyladenosine transferase

Products: NA

Alternate protein names: 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase; 16S rRNA dimethyladenosine transferase; 16S rRNA dimethylase; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MDNGIRPILEIGCGKGNITRFLEPDICIELDDKMIEYLKNFNLVIADARYLPVLRGQLVSSLPYQITSDFFKEVIKLNNI
RKLTLILQKDFVDKIFNDSTYISFLLNYIYNIQIKDIIPPSCFSPRPKVYSIITIFNRIREYDKEVDSILSCISRYRNKT
LRKASKLCGFSSNNDLKVREFKPWQVLELLNSVG

Sequences:

>Translated_194_residues
MDNGIRPILEIGCGKGNITRFLEPDICIELDDKMIEYLKNFNLVIADARYLPVLRGQLVSSLPYQITSDFFKEVIKLNNI
RKLTLILQKDFVDKIFNDSTYISFLLNYIYNIQIKDIIPPSCFSPRPKVYSIITIFNRIREYDKEVDSILSCISRYRNKT
LRKASKLCGFSSNNDLKVREFKPWQVLELLNSVG
>Mature_194_residues
MDNGIRPILEIGCGKGNITRFLEPDICIELDDKMIEYLKNFNLVIADARYLPVLRGQLVSSLPYQITSDFFKEVIKLNNI
RKLTLILQKDFVDKIFNDSTYISFLLNYIYNIQIKDIIPPSCFSPRPKVYSIITIFNRIREYDKEVDSILSCISRYRNKT
LRKASKLCGFSSNNDLKVREFKPWQVLELLNSVG

Specific function: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits [H]

COG id: COG0030

COG function: function code J; Dimethyladenosine transferase (rRNA methylation)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023165
- InterPro:   IPR020596
- InterPro:   IPR001737
- InterPro:   IPR020598
- InterPro:   IPR011530 [H]

Pfam domain/function: PF00398 RrnaAD [H]

EC number: =2.1.1.182 [H]

Molecular weight: Translated: 22601; Mature: 22601

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNGIRPILEIGCGKGNITRFLEPDICIELDDKMIEYLKNFNLVIADARYLPVLRGQLVS
CCCCCCHHHHHCCCCCCCCEECCCCCEEEECHHHHHHHHCCCEEEECCHHHHHHHHHHHH
SLPYQITSDFFKEVIKLNNIRKLTLILQKDFVDKIFNDSTYISFLLNYIYNIQIKDIIPP
HCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEECCCCCC
SCFSPRPKVYSIITIFNRIREYDKEVDSILSCISRYRNKTLRKASKLCGFSSNNDLKVRE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
FKPWQVLELLNSVG
CCCHHHHHHHHHCC
>Mature Secondary Structure
MDNGIRPILEIGCGKGNITRFLEPDICIELDDKMIEYLKNFNLVIADARYLPVLRGQLVS
CCCCCCHHHHHCCCCCCCCEECCCCCEEEECHHHHHHHHCCCEEEECCHHHHHHHHHHHH
SLPYQITSDFFKEVIKLNNIRKLTLILQKDFVDKIFNDSTYISFLLNYIYNIQIKDIIPP
HCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEECCCCCC
SCFSPRPKVYSIITIFNRIREYDKEVDSILSCISRYRNKTLRKASKLCGFSSNNDLKVRE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
FKPWQVLELLNSVG
CCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA