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The map label for this gene is trzA [H]

Identifier: 15897586

GI number: 15897586

Start: 582563

End: 583798

Strand: Direct

Name: trzA [H]

Synonym: SSO0679

Alternate gene names: 15897586

Gene position: 582563-583798 (Clockwise)

Preceding gene: 15897585

Following gene: 15897588

Centisome position: 19.47

GC content: 33.66

Gene sequence:

>1236_bases
ATGCAGATACGAAATAACGGATATACATTAAAAAATTGCAGATTTATTGTAAACTATGATAAAATATTGGAAAACGTGAA
CATAGTAATACAAAATGGATATATAAAAAATGTAGGAAGGGAAGTTGAGGGAGATGAGGTAGATTGCTCAGAATACATTG
CAATACCAGGGCTAGTTAACGCACATACACATACTCCAATGATAATATTGCGTGGATATTATGACGATGCCGAATTAACA
GAATGGCTAAAAAAGATATGGGAATTTGAAAAAGTTTTCAAGCTAAATGAGATGAACATAGCCTCAGAGTTGGCTATAAT
GGAAATGTTATCAAAAGGTACAACAGCTTTCATAGACATGTACTTTAATCCTGAAGGAGTAAAAGAAATTGCAGAAAAGT
ATGGAATAAGGGCCTATGCTGGTTATACGTTTCTAAACAGTTTATTCGAGCCTCATGAGATAGATAAGAAACAAAGACAG
CTTAAAACAAGTGAACTGTTTAAACCAATTGTGAACGTACATAGCATTTATTCAACATCTATAGAAACATTAAAATTGGC
TAAACAAATTGCAGAGGAAACAGACACATGGATTCACATCCATGTATCTGAGACCAGAAGCGAGATTTATGAGATAAAGA
AAAAATATGGCAAGTTCCCAGTAGAGTTATTGAATGAGCTAGGAATCGTAAAAAATGCTCAGTTAGTCCATTTAGGATGG
ATAGCTAATTGGGAATTACGATATGTGAACCAAGCAACTCATTGTCCTACATCGAATATGAAACTTGCTACCGCAGGTTT
CTTTCCATTTAAAGAATTGATGGAAAATGGAGTAAACATAACCATAGGTACAGATGGAGCAGCGAGTAATAACTCGTTAG
ATATGTTTAGAGAGATGAAAAATGCAGTATTGCTCCAAAGACATTCGTATTGGGATGTTGGAGTAAAGGCATTTCATGCA
TTTAGGGCAGCAACAGAAAATGGATACAAACTTATTAATTTAAAAGGAGGAAGAATAGAAGAAGGTTACATTGCTGATAT
AGTATTATTAAAGAAGGACAAATTATATCCGCTAAGGAAGGATAGGATTCTATCAAACATTGTTTATTATACCGTAGGTG
AATATGTAGGTAAGGTTATAGTAAATGGAAGAATAGTTTACGACGAAAAAGTAGAAAGGGAATTTGATAAGAGAAGAAGA
GAATTACTTAAGCTTTTGGATGAGATTATATCCTAG

Upstream 100 bases:

>100_bases
CATTTGAGGGTGGAGAAGCTGAAACTTTTGTAACTTACGCTCCACTTTTCAAAACACAATTAAGGGTAAATGGTAAATTA
AAAAGAATAAGTGAGTACGA

Downstream 100 bases:

>100_bases
ACCGTATGGGAATGAAATAGCCAAAGATAGACCGGGTATTAAATTCAATAAATATTTCTTTGGACCTTTATAATAATAGA
CACCATAACCTATGAGTGGT

Product: N-ethylammeline chlorohydrolase, putative (trzA)

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MQIRNNGYTLKNCRFIVNYDKILENVNIVIQNGYIKNVGREVEGDEVDCSEYIAIPGLVNAHTHTPMIILRGYYDDAELT
EWLKKIWEFEKVFKLNEMNIASELAIMEMLSKGTTAFIDMYFNPEGVKEIAEKYGIRAYAGYTFLNSLFEPHEIDKKQRQ
LKTSELFKPIVNVHSIYSTSIETLKLAKQIAEETDTWIHIHVSETRSEIYEIKKKYGKFPVELLNELGIVKNAQLVHLGW
IANWELRYVNQATHCPTSNMKLATAGFFPFKELMENGVNITIGTDGAASNNSLDMFREMKNAVLLQRHSYWDVGVKAFHA
FRAATENGYKLINLKGGRIEEGYIADIVLLKKDKLYPLRKDRILSNIVYYTVGEYVGKVIVNGRIVYDEKVEREFDKRRR
ELLKLLDEIIS

Sequences:

>Translated_411_residues
MQIRNNGYTLKNCRFIVNYDKILENVNIVIQNGYIKNVGREVEGDEVDCSEYIAIPGLVNAHTHTPMIILRGYYDDAELT
EWLKKIWEFEKVFKLNEMNIASELAIMEMLSKGTTAFIDMYFNPEGVKEIAEKYGIRAYAGYTFLNSLFEPHEIDKKQRQ
LKTSELFKPIVNVHSIYSTSIETLKLAKQIAEETDTWIHIHVSETRSEIYEIKKKYGKFPVELLNELGIVKNAQLVHLGW
IANWELRYVNQATHCPTSNMKLATAGFFPFKELMENGVNITIGTDGAASNNSLDMFREMKNAVLLQRHSYWDVGVKAFHA
FRAATENGYKLINLKGGRIEEGYIADIVLLKKDKLYPLRKDRILSNIVYYTVGEYVGKVIVNGRIVYDEKVEREFDKRRR
ELLKLLDEIIS
>Mature_411_residues
MQIRNNGYTLKNCRFIVNYDKILENVNIVIQNGYIKNVGREVEGDEVDCSEYIAIPGLVNAHTHTPMIILRGYYDDAELT
EWLKKIWEFEKVFKLNEMNIASELAIMEMLSKGTTAFIDMYFNPEGVKEIAEKYGIRAYAGYTFLNSLFEPHEIDKKQRQ
LKTSELFKPIVNVHSIYSTSIETLKLAKQIAEETDTWIHIHVSETRSEIYEIKKKYGKFPVELLNELGIVKNAQLVHLGW
IANWELRYVNQATHCPTSNMKLATAGFFPFKELMENGVNITIGTDGAASNNSLDMFREMKNAVLLQRHSYWDVGVKAFHA
FRAATENGYKLINLKGGRIEEGYIADIVLLKKDKLYPLRKDRILSNIVYYTVGEYVGKVIVNGRIVYDEKVEREFDKRRR
ELLKLLDEIIS

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=331, Percent_Identity=26.8882175226586, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI87082177, Length=407, Percent_Identity=22.8501228501229, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789249, Length=425, Percent_Identity=25.6470588235294, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 47536; Mature: 47536

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIRNNGYTLKNCRFIVNYDKILENVNIVIQNGYIKNVGREVEGDEVDCSEYIAIPGLVN
CEECCCCEEEECCEEEEEHHHHHCCCEEEEECCCHHHCCCCCCCCCCCCHHEEECCCCCC
AHTHTPMIILRGYYDDAELTEWLKKIWEFEKVFKLNEMNIASELAIMEMLSKGTTAFIDM
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEE
YFNPEGVKEIAEKYGIRAYAGYTFLNSLFEPHEIDKKQRQLKTSELFKPIVNVHSIYSTS
EECCHHHHHHHHHCCCEEEHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
IETLKLAKQIAEETDTWIHIHVSETRSEIYEIKKKYGKFPVELLNELGIVKNAQLVHLGW
HHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEEE
IANWELRYVNQATHCPTSNMKLATAGFFPFKELMENGVNITIGTDGAASNNSLDMFREMK
EECCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHH
NAVLLQRHSYWDVGVKAFHAFRAATENGYKLINLKGGRIEEGYIADIVLLKKDKLYPLRK
HHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCCHH
DRILSNIVYYTVGEYVGKVIVNGRIVYDEKVEREFDKRRRELLKLLDEIIS
HHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MQIRNNGYTLKNCRFIVNYDKILENVNIVIQNGYIKNVGREVEGDEVDCSEYIAIPGLVN
CEECCCCEEEECCEEEEEHHHHHCCCEEEEECCCHHHCCCCCCCCCCCCHHEEECCCCCC
AHTHTPMIILRGYYDDAELTEWLKKIWEFEKVFKLNEMNIASELAIMEMLSKGTTAFIDM
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEE
YFNPEGVKEIAEKYGIRAYAGYTFLNSLFEPHEIDKKQRQLKTSELFKPIVNVHSIYSTS
EECCHHHHHHHHHCCCEEEHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
IETLKLAKQIAEETDTWIHIHVSETRSEIYEIKKKYGKFPVELLNELGIVKNAQLVHLGW
HHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEEE
IANWELRYVNQATHCPTSNMKLATAGFFPFKELMENGVNITIGTDGAASNNSLDMFREMK
EECCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHH
NAVLLQRHSYWDVGVKAFHAFRAATENGYKLINLKGGRIEEGYIADIVLLKKDKLYPLRK
HHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCCHH
DRILSNIVYYTVGEYVGKVIVNGRIVYDEKVEREFDKRRRELLKLLDEIIS
HHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA