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The map label for this gene is purL [H]

Identifier: 15897545

GI number: 15897545

Start: 544450

End: 546579

Strand: Direct

Name: purL [H]

Synonym: SSO0629

Alternate gene names: 15897545

Gene position: 544450-546579 (Clockwise)

Preceding gene: 15897544

Following gene: 15897546

Centisome position: 18.2

GC content: 36.48

Gene sequence:

>2130_bases
ATGGGCATAAATCTTCTCCCTATAGAGATGGACGAGATTCGAAAAAGACTAGGTAGAGAACCTAATGAGACCGAATGGAG
AGTTATTGATGCAGTATGGTCAGAGCATTGCTCTTATAAATCATCTAAAATCTTCTTAAAGAGCTTTTCCATAGATAGTC
CTAATGTTATAATGGGCATAAAAGACTGGCAAGATGCTGGAGCGGTAGATATAGGAGATGGATGGGCAGTAGTAATAAAG
GTTGAAAGCCATAACCATCCTTCTGCCATTGATCCATTCAATGGTGCTGCAACTGGTGTAGGAGGAATAATAAGGGACAT
TATTAGCAAGGGGGCAAAGCCAATTGCACTTATGGACATGATAAGGGTTGGAAATCTGAAAATAAAGAAAAACGTATGGT
TGCTTAAGAACATAATTGCAGGGATTGCGGCTTATGGCAATAGTATTGGAGTCCCGGTAGTTGGTGGAGAATTATCATTC
GATGATACATATAATGATAATCCGCTAGTAGATGTAGCAGCGATCGGAATAGTTAGAAAAGACAAGATAAAACCAAGTAT
TGTAGATAAAGCGGGACTTAAATTAGTGTTAGCTGGACTAACCGGAGTTGATGGTTTAGGCGGAGCTTCATTTGCGTCTA
GAAAGTTAAGTGGTGAAGACGAAATTGGAGCAGTACAGATAGCTGATCCTTTTGCTGGGAAAATTATATTGGATGTAACC
TTAGAAATCGCTGATAAAGTAGAGGCTATTAAAGACTTAGGTGGTGGAGGGCTAGCAGTTGCTGTAACTGAGATAACAAA
CGGACTTGGTGCTACAGTAGATATAGAGAAAATTCCATTACGTGTAAAAAATATGAATCCGTCAGATGTAATCATATCTG
AAACACAAGAGAGAATGTTATATGCAGTGGAGGAGAAAAACGTTAAGGAAGTTTGCGAAGCTTTTGAAGAATACGAATAC
CCTTGCAGTGTAATAGGTGAGATAACTAATGAACCAGTAATTAAGTTTAGATATATTGGTAAAGATCTCGTCTCCCTACC
CACAAACGTATTATTAAACCCGCCGAGGTTTTTATGGCCAATAAAAAACACTAAGAAAAATGTTGAAGAGAAAATTGTTG
ATTTACCGTTAGAAAGTGCAATTTATACTGTATTAACACATCCAGATTTAGTAAGTAAAGGATGGGCCTATTCACAGTTT
GATTATGAAGTAAATACCTCAACAGTAGTTAAACCCGGTGATGCTGATAGTGCAGTAGTCTCGCTTCCTAATGGTAAGTT
ATTGGCGATAAAAGCGGATGCAAATCCTGACATGTGCGCTGAGGATGGATATGAGTGCGGAAAAGGAATAGTAGCAGAGG
CCTATAGGAATTTAGCTACAGTAGGGGCTAGAGGAATGGTAGCAGTTGATCATTTACAGTTTGGGGATCCAAAGAAGGCA
GAAGTTTACTATACTTTCGTAGAAGCAATAAGAGGTATAGGAGAGGCTACTAGATTCTTTAACATACCTATTGTTGGTGG
GAAAGTTTCATTTTATAATGAAAATAATCAAGGAAGACCAATAAAGCCAACACCTTTAATAGTTATGGCAGGGTTAGTTC
AAGATAAATTACTTAAAAATAGAGTGGAAGACAACTTATACGTTGTATCAGTAGGGTATACGCGAAAAGAATTAGGGGGA
TCATTATTATCAAAGATATTTAAGATACCTAGTCAAGCTCCTAAAGTAAGATTACAAGAGGATCTGTTATCTTCTGAGGT
AGTAATTGATTCTATAAATGAGGGGAAAATTACATTTGCGAAAGATGTAAGTAGAGGTGGCCTAGCGGCATCTCTTTTTA
GCATACTAGTTCATGGATATGGAGTAGAAATCAGTACTAAGAGTATTTTAAGCGATACTGACAATGTTATAGAGAATCTA
TTCTCTGAAAGTAGTGGACGTTTCATAGTCTTAACTAATGAACCAGAATGGATAGTTGAAAAGAGTAAGAGTAAAGGTAT
TGTAGCATCTATAATAGGAAGGGTCAATAAAAAAACTAATATTTTAACTATTGATAATATAGATTATAATCTTAAAAATA
TAGTTGATAATTACTTTAATTTTCTAGAAGAGGTAATGGGTAATGGATAG

Upstream 100 bases:

>100_bases
ATGTAATAGGAATGATGCCACATCCAGAAAGGGCTTCCTTTAAACTGACTTCAATTGACGGAACTGTTGACGGGTTAATT
CTTTTGAGGAGGTTAGGAGA

Downstream 100 bases:

>100_bases
CATACGTGATAAATGTGGAGTCTTTGCTGTATCTAGCCCTAAAGAAGTAAATATTCAACTGGTAGTAGAGGGAATTAGAC
TACTTCAGCATAGGGGTCAA

Product: phosphoribosylformylglycinamidine synthase II

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase II; FGAM synthase II [H]

Number of amino acids: Translated: 709; Mature: 708

Protein sequence:

>709_residues
MGINLLPIEMDEIRKRLGREPNETEWRVIDAVWSEHCSYKSSKIFLKSFSIDSPNVIMGIKDWQDAGAVDIGDGWAVVIK
VESHNHPSAIDPFNGAATGVGGIIRDIISKGAKPIALMDMIRVGNLKIKKNVWLLKNIIAGIAAYGNSIGVPVVGGELSF
DDTYNDNPLVDVAAIGIVRKDKIKPSIVDKAGLKLVLAGLTGVDGLGGASFASRKLSGEDEIGAVQIADPFAGKIILDVT
LEIADKVEAIKDLGGGGLAVAVTEITNGLGATVDIEKIPLRVKNMNPSDVIISETQERMLYAVEEKNVKEVCEAFEEYEY
PCSVIGEITNEPVIKFRYIGKDLVSLPTNVLLNPPRFLWPIKNTKKNVEEKIVDLPLESAIYTVLTHPDLVSKGWAYSQF
DYEVNTSTVVKPGDADSAVVSLPNGKLLAIKADANPDMCAEDGYECGKGIVAEAYRNLATVGARGMVAVDHLQFGDPKKA
EVYYTFVEAIRGIGEATRFFNIPIVGGKVSFYNENNQGRPIKPTPLIVMAGLVQDKLLKNRVEDNLYVVSVGYTRKELGG
SLLSKIFKIPSQAPKVRLQEDLLSSEVVIDSINEGKITFAKDVSRGGLAASLFSILVHGYGVEISTKSILSDTDNVIENL
FSESSGRFIVLTNEPEWIVEKSKSKGIVASIIGRVNKKTNILTIDNIDYNLKNIVDNYFNFLEEVMGNG

Sequences:

>Translated_709_residues
MGINLLPIEMDEIRKRLGREPNETEWRVIDAVWSEHCSYKSSKIFLKSFSIDSPNVIMGIKDWQDAGAVDIGDGWAVVIK
VESHNHPSAIDPFNGAATGVGGIIRDIISKGAKPIALMDMIRVGNLKIKKNVWLLKNIIAGIAAYGNSIGVPVVGGELSF
DDTYNDNPLVDVAAIGIVRKDKIKPSIVDKAGLKLVLAGLTGVDGLGGASFASRKLSGEDEIGAVQIADPFAGKIILDVT
LEIADKVEAIKDLGGGGLAVAVTEITNGLGATVDIEKIPLRVKNMNPSDVIISETQERMLYAVEEKNVKEVCEAFEEYEY
PCSVIGEITNEPVIKFRYIGKDLVSLPTNVLLNPPRFLWPIKNTKKNVEEKIVDLPLESAIYTVLTHPDLVSKGWAYSQF
DYEVNTSTVVKPGDADSAVVSLPNGKLLAIKADANPDMCAEDGYECGKGIVAEAYRNLATVGARGMVAVDHLQFGDPKKA
EVYYTFVEAIRGIGEATRFFNIPIVGGKVSFYNENNQGRPIKPTPLIVMAGLVQDKLLKNRVEDNLYVVSVGYTRKELGG
SLLSKIFKIPSQAPKVRLQEDLLSSEVVIDSINEGKITFAKDVSRGGLAASLFSILVHGYGVEISTKSILSDTDNVIENL
FSESSGRFIVLTNEPEWIVEKSKSKGIVASIIGRVNKKTNILTIDNIDYNLKNIVDNYFNFLEEVMGNG
>Mature_708_residues
GINLLPIEMDEIRKRLGREPNETEWRVIDAVWSEHCSYKSSKIFLKSFSIDSPNVIMGIKDWQDAGAVDIGDGWAVVIKV
ESHNHPSAIDPFNGAATGVGGIIRDIISKGAKPIALMDMIRVGNLKIKKNVWLLKNIIAGIAAYGNSIGVPVVGGELSFD
DTYNDNPLVDVAAIGIVRKDKIKPSIVDKAGLKLVLAGLTGVDGLGGASFASRKLSGEDEIGAVQIADPFAGKIILDVTL
EIADKVEAIKDLGGGGLAVAVTEITNGLGATVDIEKIPLRVKNMNPSDVIISETQERMLYAVEEKNVKEVCEAFEEYEYP
CSVIGEITNEPVIKFRYIGKDLVSLPTNVLLNPPRFLWPIKNTKKNVEEKIVDLPLESAIYTVLTHPDLVSKGWAYSQFD
YEVNTSTVVKPGDADSAVVSLPNGKLLAIKADANPDMCAEDGYECGKGIVAEAYRNLATVGARGMVAVDHLQFGDPKKAE
VYYTFVEAIRGIGEATRFFNIPIVGGKVSFYNENNQGRPIKPTPLIVMAGLVQDKLLKNRVEDNLYVVSVGYTRKELGGS
LLSKIFKIPSQAPKVRLQEDLLSSEVVIDSINEGKITFAKDVSRGGLAASLFSILVHGYGVEISTKSILSDTDNVIENLF
SESSGRFIVLTNEPEWIVEKSKSKGIVASIIGRVNKKTNILTIDNIDYNLKNIVDNYFNFLEEVMGNG

Specific function: Unknown

COG id: COG0046

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGAMS family [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=797, Percent_Identity=23.9648682559598, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17553022, Length=706, Percent_Identity=22.8045325779037, Blast_Score=86, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321498, Length=468, Percent_Identity=27.3504273504274, Blast_Score=105, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR010074
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 77089; Mature: 76958

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00659 GLYCOSYL_HYDROL_F5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGINLLPIEMDEIRKRLGREPNETEWRVIDAVWSEHCSYKSSKIFLKSFSIDSPNVIMGI
CCCEEEECCHHHHHHHHCCCCCCCHHEEHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEE
KDWQDAGAVDIGDGWAVVIKVESHNHPSAIDPFNGAATGVGGIIRDIISKGAKPIALMDM
CCCCCCCCEEECCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHH
IRVGNLKIKKNVWLLKNIIAGIAAYGNSIGVPVVGGELSFDDTYNDNPLVDVAAIGIVRK
HHHCCEEEECCHHHHHHHHHHHHHCCCCCCCEEECCEECCCCCCCCCCCEEHHHCCEEEC
DKIKPSIVDKAGLKLVLAGLTGVDGLGGASFASRKLSGEDEIGAVQIADPFAGKIILDVT
CCCCCHHHHHCCCEEEEECCCCCCCCCCCHHHHCCCCCCCCCCEEEECCCCCCEEEEEEE
LEIADKVEAIKDLGGGGLAVAVTEITNGLGATVDIEKIPLRVKNMNPSDVIISETQERML
HHHHHHHHHHHHCCCCCEEEEEEEHHCCCCCEEEEEECCEEEECCCCCCEEEECCHHHHE
YAVEEKNVKEVCEAFEEYEYPCSVIGEITNEPVIKFRYIGKDLVSLPTNVLLNPPRFLWP
EEHHHCCHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEECCCHHHHCCCCCEECCCCEEEC
IKNTKKNVEEKIVDLPLESAIYTVLTHPDLVSKGWAYSQFDYEVNTSTVVKPGDADSAVV
CCCHHHHHHHHHHCCCHHHHHEEEEECCCHHHCCCCEEEEEEEECCCEEECCCCCCCEEE
SLPNGKLLAIKADANPDMCAEDGYECGKGIVAEAYRNLATVGARGMVAVDHLQFGDPKKA
ECCCCEEEEEEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCEEEECEECCCCCCC
EVYYTFVEAIRGIGEATRFFNIPIVGGKVSFYNENNQGRPIKPTPLIVMAGLVQDKLLKN
HHHHHHHHHHHCCCHHHHEEECEEECCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
RVEDNLYVVSVGYTRKELGGSLLSKIFKIPSQAPKVRLQEDLLSSEVVIDSINEGKITFA
HCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEECCCCCCEEEE
KDVSRGGLAASLFSILVHGYGVEISTKSILSDTDNVIENLFSESSGRFIVLTNEPEWIVE
CCCCCCCHHHHHHHHHHHCCCCEEEHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCEEEE
KSKSKGIVASIIGRVNKKTNILTIDNIDYNLKNIVDNYFNFLEEVMGNG
CCCCCCHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GINLLPIEMDEIRKRLGREPNETEWRVIDAVWSEHCSYKSSKIFLKSFSIDSPNVIMGI
CCEEEECCHHHHHHHHCCCCCCCHHEEHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEE
KDWQDAGAVDIGDGWAVVIKVESHNHPSAIDPFNGAATGVGGIIRDIISKGAKPIALMDM
CCCCCCCCEEECCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHH
IRVGNLKIKKNVWLLKNIIAGIAAYGNSIGVPVVGGELSFDDTYNDNPLVDVAAIGIVRK
HHHCCEEEECCHHHHHHHHHHHHHCCCCCCCEEECCEECCCCCCCCCCCEEHHHCCEEEC
DKIKPSIVDKAGLKLVLAGLTGVDGLGGASFASRKLSGEDEIGAVQIADPFAGKIILDVT
CCCCCHHHHHCCCEEEEECCCCCCCCCCCHHHHCCCCCCCCCCEEEECCCCCCEEEEEEE
LEIADKVEAIKDLGGGGLAVAVTEITNGLGATVDIEKIPLRVKNMNPSDVIISETQERML
HHHHHHHHHHHHCCCCCEEEEEEEHHCCCCCEEEEEECCEEEECCCCCCEEEECCHHHHE
YAVEEKNVKEVCEAFEEYEYPCSVIGEITNEPVIKFRYIGKDLVSLPTNVLLNPPRFLWP
EEHHHCCHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEECCCHHHHCCCCCEECCCCEEEC
IKNTKKNVEEKIVDLPLESAIYTVLTHPDLVSKGWAYSQFDYEVNTSTVVKPGDADSAVV
CCCHHHHHHHHHHCCCHHHHHEEEEECCCHHHCCCCEEEEEEEECCCEEECCCCCCCEEE
SLPNGKLLAIKADANPDMCAEDGYECGKGIVAEAYRNLATVGARGMVAVDHLQFGDPKKA
ECCCCEEEEEEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCEEEECEECCCCCCC
EVYYTFVEAIRGIGEATRFFNIPIVGGKVSFYNENNQGRPIKPTPLIVMAGLVQDKLLKN
HHHHHHHHHHHCCCHHHHEEECEEECCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
RVEDNLYVVSVGYTRKELGGSLLSKIFKIPSQAPKVRLQEDLLSSEVVIDSINEGKITFA
HCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEECCCCCCEEEE
KDVSRGGLAASLFSILVHGYGVEISTKSILSDTDNVIENLFSESSGRFIVLTNEPEWIVE
CCCCCCCHHHHHHHHHHHCCCCEEEHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCEEEE
KSKSKGIVASIIGRVNKKTNILTIDNIDYNLKNIVDNYFNFLEEVMGNG
CCCCCCHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA