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The map label for this gene is atpA [H]

Identifier: 15897484

GI number: 15897484

Start: 496480

End: 498258

Strand: Direct

Name: atpA [H]

Synonym: SSO0563

Alternate gene names: 15897484

Gene position: 496480-498258 (Clockwise)

Preceding gene: 15897483

Following gene: 15897485

Centisome position: 16.59

GC content: 39.29

Gene sequence:

>1779_bases
ATGGATAATGGAAGGATTGTCAGGATAAATGGTCCATTAGTCGTAGCAGATAACATGAGAAATGCACAGATGTATGAAGT
AGTAGAAGTTGGAGAGCCTAGATTAATCGGAGAGATTACTAGAATAGAAGGAGATAGAGCATTCATTCAAGTTTATGAAG
ACACTAGTGGAATAAAACCAAATGAGCCAGTGTACAGAACGGGTGCTCCTCTGTCAATAGAGCTGGGTCCAGGCTTAATA
GGAAAAATATTTGATGGATTACAAAGGCCACTAGACTCAATCAAAGAGCTCACAAAATCTCCTTTTATAGCAAGAGGTAT
AAAGGTTCCATCCATCGATAGAAAAACCAAATGGCACTTTGTGCCTAAAGTTAAGAAAGGAGATAAGGTCGAAGGTGGAA
GCATCATAGGAATAGTAAACGAAACTCCATTAGTAGAGCATAGAATTCTAGTTCCTCCCTATGTTCACGGCACCTTAAAG
GAAGTCGTTGCAGAGGGAGATTATACAGTTGAAGATCCGATAGCGATTGTTGATATGAATGGCGATGAGGTACCAGTGAA
GTTAATGCAAAAGTGGCCAGTTAGAATTCCTAGACCGTTTAAAGAGAAGCTAGAGCCAACTGAACCATTATTAACTGGAA
CCAGAGTACTGGATACGATATTCCCAATAGCTAAAGGAGGAACAGCAGCAATACCAGGGCCCTTTGGAAGTGGAAAAACA
GTCACATTGCAGAGTTTAGCTAAGTGGAGTGCCGCAAAAATAGTAATTTATGTGGGATGTGGTGAGAGAGGAAACGAGAT
GACAGATGAGTTAAGACAATTCCCAAGTCTTAAAGATCCTTGGACTGGTAGACCCTTGTTAGAAAGGACAATACTAGTTG
CTAATACAAGCAATATGCCAGTAGCAGCTAGGGAAGCAAGTATATATGTTGGTATAACTATGGCAGAGTATTTCAGAGAT
CAAGGATATGATACATTACTAGTTGCAGATTCAACTTCGAGATGGGCTGAAGCTCTAAGAGATTTAGGAGGAAGAATGGA
GGAAATGCCAGCGGAAGAGGGATTCCCAAGCTATTTACCATCTAGACTTGCAGAATATTATGAGAGAGCTGGAAGAGTTA
AAACAATAGGAAATCCAGAAAGATTTGGTTCAGTTACCGTTGCTTCTGCAGTATCTCCACCTGGTGGAGATTTCACAGAA
CCAGTAACAAGCCAAACGTTAAGATTCGTTAAAGTTTTCTGGCCTTTAGATGTATCATTAGCACAAGCCAGACACTATCC
AGCTATTAATTGGCTTCAAGGATTCTCAGCATATGTAGACTTGGTAGCAAATTGGTGGAACACGAATGTAGATCCAAAGT
GGAGGGAAATGAGAGATATGATGGTAAGGACACTGATTAGAGAGGACGAGTTAAGACAAATAGTTAGATTAGTAGGACCA
GAATCTCTAGCAGAAAAGGATAAATTAATACTCGAAACAGCAAGGTTAATTAAAGAGGCATTCTTAAAGCAAAACGCCTA
TGACGATATAGATGCCTTCTCTTCTCCACAGAAGCAAGCTAGAATAATGAGATTAATTTACCTATTTAACACATATGCTT
CTAAATTAGTTGAAAGGGGAATTCCTACGAAGAAAATAGTAGATAGTATGGGACAGCTCTTACCAGAGATTATTAGATCG
AAAGCCGCAATCAAGAACGATGAGTTAAATAGGTATGATGAGTTAGAGAGAAAATTAATTACTGTCTTTGAGAATTTGGA
AAAGGAGGCTGGTACTTAA

Upstream 100 bases:

>100_bases
GTGGATTAACAAGAGATTTTTCATTAAAGCTTATCTTAGACCAAGTTTTTGATAGTATGAGGGGAAAGATTTCAGACATG
TTGTTTGGAGGTAAGTAAAA

Downstream 100 bases:

>100_bases
TGTTAAGCGTAAGGGAATTTTCAAACATATCTATGATTAAAGGCCCACTAGTTTATGTTCAAGGAGTAACGGATGCATCA
TATAACGAGCTAGTAGAAAT

Product: V-type ATP synthase subunit A

Products: NA

Alternate protein names: V-ATPase subunit A [H]

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MDNGRIVRINGPLVVADNMRNAQMYEVVEVGEPRLIGEITRIEGDRAFIQVYEDTSGIKPNEPVYRTGAPLSIELGPGLI
GKIFDGLQRPLDSIKELTKSPFIARGIKVPSIDRKTKWHFVPKVKKGDKVEGGSIIGIVNETPLVEHRILVPPYVHGTLK
EVVAEGDYTVEDPIAIVDMNGDEVPVKLMQKWPVRIPRPFKEKLEPTEPLLTGTRVLDTIFPIAKGGTAAIPGPFGSGKT
VTLQSLAKWSAAKIVIYVGCGERGNEMTDELRQFPSLKDPWTGRPLLERTILVANTSNMPVAAREASIYVGITMAEYFRD
QGYDTLLVADSTSRWAEALRDLGGRMEEMPAEEGFPSYLPSRLAEYYERAGRVKTIGNPERFGSVTVASAVSPPGGDFTE
PVTSQTLRFVKVFWPLDVSLAQARHYPAINWLQGFSAYVDLVANWWNTNVDPKWREMRDMMVRTLIREDELRQIVRLVGP
ESLAEKDKLILETARLIKEAFLKQNAYDDIDAFSSPQKQARIMRLIYLFNTYASKLVERGIPTKKIVDSMGQLLPEIIRS
KAAIKNDELNRYDELERKLITVFENLEKEAGT

Sequences:

>Translated_592_residues
MDNGRIVRINGPLVVADNMRNAQMYEVVEVGEPRLIGEITRIEGDRAFIQVYEDTSGIKPNEPVYRTGAPLSIELGPGLI
GKIFDGLQRPLDSIKELTKSPFIARGIKVPSIDRKTKWHFVPKVKKGDKVEGGSIIGIVNETPLVEHRILVPPYVHGTLK
EVVAEGDYTVEDPIAIVDMNGDEVPVKLMQKWPVRIPRPFKEKLEPTEPLLTGTRVLDTIFPIAKGGTAAIPGPFGSGKT
VTLQSLAKWSAAKIVIYVGCGERGNEMTDELRQFPSLKDPWTGRPLLERTILVANTSNMPVAAREASIYVGITMAEYFRD
QGYDTLLVADSTSRWAEALRDLGGRMEEMPAEEGFPSYLPSRLAEYYERAGRVKTIGNPERFGSVTVASAVSPPGGDFTE
PVTSQTLRFVKVFWPLDVSLAQARHYPAINWLQGFSAYVDLVANWWNTNVDPKWREMRDMMVRTLIREDELRQIVRLVGP
ESLAEKDKLILETARLIKEAFLKQNAYDDIDAFSSPQKQARIMRLIYLFNTYASKLVERGIPTKKIVDSMGQLLPEIIRS
KAAIKNDELNRYDELERKLITVFENLEKEAGT
>Mature_592_residues
MDNGRIVRINGPLVVADNMRNAQMYEVVEVGEPRLIGEITRIEGDRAFIQVYEDTSGIKPNEPVYRTGAPLSIELGPGLI
GKIFDGLQRPLDSIKELTKSPFIARGIKVPSIDRKTKWHFVPKVKKGDKVEGGSIIGIVNETPLVEHRILVPPYVHGTLK
EVVAEGDYTVEDPIAIVDMNGDEVPVKLMQKWPVRIPRPFKEKLEPTEPLLTGTRVLDTIFPIAKGGTAAIPGPFGSGKT
VTLQSLAKWSAAKIVIYVGCGERGNEMTDELRQFPSLKDPWTGRPLLERTILVANTSNMPVAAREASIYVGITMAEYFRD
QGYDTLLVADSTSRWAEALRDLGGRMEEMPAEEGFPSYLPSRLAEYYERAGRVKTIGNPERFGSVTVASAVSPPGGDFTE
PVTSQTLRFVKVFWPLDVSLAQARHYPAINWLQGFSAYVDLVANWWNTNVDPKWREMRDMMVRTLIREDELRQIVRLVGP
ESLAEKDKLILETARLIKEAFLKQNAYDDIDAFSSPQKQARIMRLIYLFNTYASKLVERGIPTKKIVDSMGQLLPEIIRS
KAAIKNDELNRYDELERKLITVFENLEKEAGT

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit [H]

COG id: COG1155

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI19913424, Length=599, Percent_Identity=47.9131886477462, Blast_Score=563, Evalue=1e-160,
Organism=Homo sapiens, GI32189394, Length=330, Percent_Identity=29.3939393939394, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI19913426, Length=341, Percent_Identity=24.3401759530792, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI19913428, Length=351, Percent_Identity=24.2165242165242, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI50345984, Length=253, Percent_Identity=25.6916996047431, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4757810, Length=253, Percent_Identity=25.6916996047431, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1790170, Length=333, Percent_Identity=29.7297297297297, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1790172, Length=242, Percent_Identity=28.5123966942149, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1788251, Length=226, Percent_Identity=28.7610619469027, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17565854, Length=603, Percent_Identity=49.0878938640133, Blast_Score=578, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI25144756, Length=312, Percent_Identity=29.4871794871795, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17510931, Length=324, Percent_Identity=25.6172839506173, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17570191, Length=335, Percent_Identity=24.7761194029851, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71988080, Length=253, Percent_Identity=26.0869565217391, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71988063, Length=253, Percent_Identity=26.0869565217391, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71988074, Length=253, Percent_Identity=26.0869565217391, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320016, Length=326, Percent_Identity=47.5460122699387, Blast_Score=312, Evalue=8e-86,
Organism=Saccharomyces cerevisiae, GI6322581, Length=329, Percent_Identity=31.0030395136778, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6319603, Length=356, Percent_Identity=26.9662921348315, Blast_Score=94, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6319370, Length=239, Percent_Identity=25.5230125523013, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583988, Length=598, Percent_Identity=49.1638795986622, Blast_Score=589, Evalue=1e-168,
Organism=Drosophila melanogaster, GI24583986, Length=598, Percent_Identity=49.1638795986622, Blast_Score=589, Evalue=1e-168,
Organism=Drosophila melanogaster, GI24583984, Length=598, Percent_Identity=49.1638795986622, Blast_Score=589, Evalue=1e-168,
Organism=Drosophila melanogaster, GI24583992, Length=598, Percent_Identity=48.494983277592, Blast_Score=574, Evalue=1e-164,
Organism=Drosophila melanogaster, GI20129479, Length=591, Percent_Identity=48.2233502538071, Blast_Score=562, Evalue=1e-160,
Organism=Drosophila melanogaster, GI24638766, Length=306, Percent_Identity=30.0653594771242, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28574560, Length=357, Percent_Identity=29.1316526610644, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI281361666, Length=340, Percent_Identity=23.8235294117647, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646341, Length=340, Percent_Identity=23.8235294117647, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17136796, Length=340, Percent_Identity=23.8235294117647, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24658560, Length=254, Percent_Identity=25.5905511811024, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR005726
- InterPro:   IPR003593
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- InterPro:   IPR022878 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 66412; Mature: 66412

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNGRIVRINGPLVVADNMRNAQMYEVVEVGEPRLIGEITRIEGDRAFIQVYEDTSGIKP
CCCCEEEEECCCEEEECCCCCCHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCCC
NEPVYRTGAPLSIELGPGLIGKIFDGLQRPLDSIKELTKSPFIARGIKVPSIDRKTKWHF
CCCCEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCEEE
VPKVKKGDKVEGGSIIGIVNETPLVEHRILVPPYVHGTLKEVVAEGDYTVEDPIAIVDMN
CCCCCCCCCCCCCCEEEEECCCCCCCCEEECCCHHHHHHHHHHHCCCCEECCCEEEEECC
GDEVPVKLMQKWPVRIPRPFKEKLEPTEPLLTGTRVLDTIFPIAKGGTAAIPGPFGSGKT
CCCCHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
VTLQSLAKWSAAKIVIYVGCGERGNEMTDELRQFPSLKDPWTGRPLLERTILVANTSNMP
EEHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCHHHHCEEEEEECCCCC
VAAREASIYVGITMAEYFRDQGYDTLLVADSTSRWAEALRDLGGRMEEMPAEEGFPSYLP
EEEECCEEEEEEHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCHHHHCCCCCCCHHHHH
SRLAEYYERAGRVKTIGNPERFGSVTVASAVSPPGGDFTEPVTSQTLRFVKVFWPLDVSL
HHHHHHHHHCCCEEECCCHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
AQARHYPAINWLQGFSAYVDLVANWWNTNVDPKWREMRDMMVRTLIREDELRQIVRLVGP
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ESLAEKDKLILETARLIKEAFLKQNAYDDIDAFSSPQKQARIMRLIYLFNTYASKLVERG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
IPTKKIVDSMGQLLPEIIRSKAAIKNDELNRYDELERKLITVFENLEKEAGT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDNGRIVRINGPLVVADNMRNAQMYEVVEVGEPRLIGEITRIEGDRAFIQVYEDTSGIKP
CCCCEEEEECCCEEEECCCCCCHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCCC
NEPVYRTGAPLSIELGPGLIGKIFDGLQRPLDSIKELTKSPFIARGIKVPSIDRKTKWHF
CCCCEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCEEE
VPKVKKGDKVEGGSIIGIVNETPLVEHRILVPPYVHGTLKEVVAEGDYTVEDPIAIVDMN
CCCCCCCCCCCCCCEEEEECCCCCCCCEEECCCHHHHHHHHHHHCCCCEECCCEEEEECC
GDEVPVKLMQKWPVRIPRPFKEKLEPTEPLLTGTRVLDTIFPIAKGGTAAIPGPFGSGKT
CCCCHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
VTLQSLAKWSAAKIVIYVGCGERGNEMTDELRQFPSLKDPWTGRPLLERTILVANTSNMP
EEHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCHHHHCEEEEEECCCCC
VAAREASIYVGITMAEYFRDQGYDTLLVADSTSRWAEALRDLGGRMEEMPAEEGFPSYLP
EEEECCEEEEEEHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCHHHHCCCCCCCHHHHH
SRLAEYYERAGRVKTIGNPERFGSVTVASAVSPPGGDFTEPVTSQTLRFVKVFWPLDVSL
HHHHHHHHHCCCEEECCCHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
AQARHYPAINWLQGFSAYVDLVANWWNTNVDPKWREMRDMMVRTLIREDELRQIVRLVGP
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ESLAEKDKLILETARLIKEAFLKQNAYDDIDAFSSPQKQARIMRLIYLFNTYASKLVERG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
IPTKKIVDSMGQLLPEIIRSKAAIKNDELNRYDELERKLITVFENLEKEAGT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA