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The map label for this gene is gch3

Identifier: 15897333

GI number: 15897333

Start: 350522

End: 351217

Strand: Reverse

Name: gch3

Synonym: SSO0399

Alternate gene names: 15897333

Gene position: 351217-350522 (Counterclockwise)

Preceding gene: 15897334

Following gene: 15897332

Centisome position: 11.74

GC content: 32.9

Gene sequence:

>696_bases
GTGAAGATATTAGCGATAAAGCTTTTAGATTATAGAGAGTGGACTGAAAGGTTAGGGTATGATAGAGAGTGGTTAATCCA
AAAAATTCAAAATAAATTTATGATGAAAATTCATGAAATAGCCTCCCAATATAACACATTTCCCCTTCAACTCAGATTTG
ACAATTTCCTAATGATAGCTGATGGGATAACTACCACTCAACTAGCATACATGATAAATGATATGCAAGAGAACCTTCCA
GTAAGGATAAAGTCTTGCCTAGGTTATGGAAAAACTCCACTAGAGGCGCAATGGAACGCGTCAATTTGTCTAAATAATCA
AGACGATAATGAAATTAAGGAATATACAGACGAAAAAATAGCCGCTTTGCATTTCGATATAAATTTTAATACGGAAACGT
TAAAATACACATCTGTATACGACTCATTTATAGAGATAACCAATATATATGTAAACTTATCAAGATTTTTATACAAGATA
GGCGGGATACTGCAATATCTAGGCGGGGATAATTATTTAGGCTTTATATCGACTGAGAGCGTCAATAAAGTAATCGAAGA
ATTTAGTGATGATAACAAGATAAAGGTAGGAATAGGAATAGGGAAAAATGCGAGAACTGCAATAAGATTGGCTACTACTT
CTTTAGAAAAAATAAGAAATAATAGGGAAAAAACTTGGCATATGGAGGAAGAATAA

Upstream 100 bases:

>100_bases
AAGAATACGCTACCAGAGCAGTAGAGGCTGCAATAAAATTAGTTCAGAGAACTAGGAAATTAGATGAATTAAAAGAAATC
AAGGAAACGGTGATCATAGA

Downstream 100 bases:

>100_bases
CACTAAATGTAAGAATAGCTCTCGTAGGAGAAGAGCTAGAAATAAGAGAGAACGTTAATATAGAAATAGAAGAAGGTATA
ATAACTCATATAGGAAATGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKILAIKLLDYREWTERLGYDREWLIQKIQNKFMMKIHEIASQYNTFPLQLRFDNFLMIADGITTTQLAYMINDMQENLP
VRIKSCLGYGKTPLEAQWNASICLNNQDDNEIKEYTDEKIAALHFDINFNTETLKYTSVYDSFIEITNIYVNLSRFLYKI
GGILQYLGGDNYLGFISTESVNKVIEEFSDDNKIKVGIGIGKNARTAIRLATTSLEKIRNNREKTWHMEEE

Sequences:

>Translated_231_residues
MKILAIKLLDYREWTERLGYDREWLIQKIQNKFMMKIHEIASQYNTFPLQLRFDNFLMIADGITTTQLAYMINDMQENLP
VRIKSCLGYGKTPLEAQWNASICLNNQDDNEIKEYTDEKIAALHFDINFNTETLKYTSVYDSFIEITNIYVNLSRFLYKI
GGILQYLGGDNYLGFISTESVNKVIEEFSDDNKIKVGIGIGKNARTAIRLATTSLEKIRNNREKTWHMEEE
>Mature_231_residues
MKILAIKLLDYREWTERLGYDREWLIQKIQNKFMMKIHEIASQYNTFPLQLRFDNFLMIADGITTTQLAYMINDMQENLP
VRIKSCLGYGKTPLEAQWNASICLNNQDDNEIKEYTDEKIAALHFDINFNTETLKYTSVYDSFIEITNIYVNLSRFLYKI
GGILQYLGGDNYLGFISTESVNKVIEEFSDDNKIKVGIGIGKNARTAIRLATTSLEKIRNNREKTWHMEEE

Specific function: Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity

COG id: COG2429

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal-type GTP cyclohydrolase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCH3_SULSO (Q980B6)

Other databases:

- EMBL:   AE006641
- PIR:   A99184
- RefSeq:   NP_341938.1
- ProteinModelPortal:   Q980B6
- GeneID:   1455538
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO0399
- NMPDR:   fig|273057.1.peg.361
- HOGENOM:   HBG553700
- OMA:   FIGGDNF
- ProtClustDB:   CLSK802708
- BioCyc:   SSOL273057:SSO0399-MONOMER
- BRENDA:   3.5.4.29
- HAMAP:   MF_00608
- InterPro:   IPR007839
- PIRSF:   PIRSF009265
- ProDom:   PD313320

Pfam domain/function: PF05165 GGDN

EC number: =3.5.4.29

Molecular weight: Translated: 27013; Mature: 27013

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILAIKLLDYREWTERLGYDREWLIQKIQNKFMMKIHEIASQYNTFPLQLRFDNFLMIA
CEEEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEE
DGITTTQLAYMINDMQENLPVRIKSCLGYGKTPLEAQWNASICLNNQDDNEIKEYTDEKI
CCCCHHHHHHHHHHHHHCCCEEEHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHHCCCEE
AALHFDINFNTETLKYTSVYDSFIEITNIYVNLSRFLYKIGGILQYLGGDNYLGFISTES
EEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHH
VNKVIEEFSDDNKIKVGIGIGKNARTAIRLATTSLEKIRNNREKTWHMEEE
HHHHHHHHCCCCEEEEEEEECCCCCCEEEEHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKILAIKLLDYREWTERLGYDREWLIQKIQNKFMMKIHEIASQYNTFPLQLRFDNFLMIA
CEEEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEE
DGITTTQLAYMINDMQENLPVRIKSCLGYGKTPLEAQWNASICLNNQDDNEIKEYTDEKI
CCCCHHHHHHHHHHHHHCCCEEEHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHHCCCEE
AALHFDINFNTETLKYTSVYDSFIEITNIYVNLSRFLYKIGGILQYLGGDNYLGFISTES
EEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHH
VNKVIEEFSDDNKIKVGIGIGKNARTAIRLATTSLEKIRNNREKTWHMEEE
HHHHHHHHCCCCEEEEEEEECCCCCCEEEEHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726