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The map label for this gene is NuoD [H]

Identifier: 15897264

GI number: 15897264

Start: 276282

End: 277514

Strand: Direct

Name: NuoD [H]

Synonym: SSO0324

Alternate gene names: 15897264

Gene position: 276282-277514 (Clockwise)

Preceding gene: 15897263

Following gene: 15897265

Centisome position: 9.23

GC content: 37.88

Gene sequence:

>1233_bases
TTGACAAGCCAACCACAGAATGAAATACAAGAACAACTACTTGCAGCTACTGGAATGTCTGTAGAATTTATACCAGTTCA
AGGAGAGCTCAATGTCGGCCCGCAACACCCTGGCTCTGGTCATATGAGAATATTTGTTAAACTAAATGGTGACATCATAG
AGGATGTAGACTTAGATGTCGGTTATGTTCATAGAGCAGTAGAAAAGCTTTCAGAAAATAGGAATTACATGCACCTTATA
CCTTTAGTAGAGAGGCCGGCGATTTTAGATTCTATACATATGAATTTAGGCTACATAATTGCGGTAGAAAAGATTTTAGG
AGTTGATGTTCCAGAAAGGGCGCAATACTTAAGGAGCTTTGCTGCGGAGGTAAATAGAATAGCTAGTCACCTCTACGGAT
TAGGAATTTTGGCAATATTCTTAGGCCATTCTACCGGTTTTATGTGGGGCTTTGGTGATAGAGAGGTATGGGTTACCATA
TTAGAAGCATTAACAGGGGCGAGGGTTACAAATTCGTACGTAATACCAGGTGGGGTTAGAAAAGATATAACTCAAGAAAT
AAAAGAAATGACCATAAAGGCTATAGCATATCAACGTAAAAGACTAGAAGATTGGAAAAAAATTTTCTTTTATAATCCAT
CGATTAGAGCGAGGCTTGAAAATGTTGGAGTTATGAGTAGAGAAAATGCAATTAAATGGGGAGCTGTCGGGCCTAATTTA
AGAGCTTCTGGAGTATACTATGACGTTCGAAAAATAGAACCATATGGGGCTTACGATAAGTTAGATTTTGAGATTCCAGT
TTACAAGGAGGGAGATGGTCTAGCAAGAGGTTTGGTAAGATTAGAGGAAATCGAACAAAGTATGAGAATATTAGAGCAGA
TAATAAAGAATATACCTGAGGGTAATATCTTATCAGATAGATTCTTCAAACAGATACCTCCTATTAGACTTAAGAAGTAT
TGGGAGACATATCGACGCATTGTATTGCCAGGCTATTACGCTTCATTTAGACCACCTAAGGGTGAAGCAATATCTAGAGT
TGAAGCTGGAAGGGGAGAGCTGGCATATTATGTAGTAAGTGATGGTTCTCCTAAGCCTTATAGATTAAGAATGATAACTC
CTTCTTATAGGTTAATATATGTTTTTAAAGAGTTATGTAAAGGTTCACGATATGCTGATTTGGTTTCGATTTATGGTAGT
CTAGATTATTTCCCTCCGGAGGCGGATAGGTAA

Upstream 100 bases:

>100_bases
GAGGGTCATCCAGATCTTAGAAGATTTTTCTTGGATGAGGATTTTGAAGGTGTATATCCATTGAGGAAGTCATATAAGAT
CAAGTTGGAGGGGGTCTTCG

Downstream 100 bases:

>100_bases
TGAGCGTTCTCTCAGCTTTGCAATATTATTTCTTTTATCCTTCATTTTTCTTAACAGTAATTTTCCCTGGTCTAATATTC
ACTCTAATTTTTCTTTTAGT

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MTSQPQNEIQEQLLAATGMSVEFIPVQGELNVGPQHPGSGHMRIFVKLNGDIIEDVDLDVGYVHRAVEKLSENRNYMHLI
PLVERPAILDSIHMNLGYIIAVEKILGVDVPERAQYLRSFAAEVNRIASHLYGLGILAIFLGHSTGFMWGFGDREVWVTI
LEALTGARVTNSYVIPGGVRKDITQEIKEMTIKAIAYQRKRLEDWKKIFFYNPSIRARLENVGVMSRENAIKWGAVGPNL
RASGVYYDVRKIEPYGAYDKLDFEIPVYKEGDGLARGLVRLEEIEQSMRILEQIIKNIPEGNILSDRFFKQIPPIRLKKY
WETYRRIVLPGYYASFRPPKGEAISRVEAGRGELAYYVVSDGSPKPYRLRMITPSYRLIYVFKELCKGSRYADLVSIYGS
LDYFPPEADR

Sequences:

>Translated_410_residues
MTSQPQNEIQEQLLAATGMSVEFIPVQGELNVGPQHPGSGHMRIFVKLNGDIIEDVDLDVGYVHRAVEKLSENRNYMHLI
PLVERPAILDSIHMNLGYIIAVEKILGVDVPERAQYLRSFAAEVNRIASHLYGLGILAIFLGHSTGFMWGFGDREVWVTI
LEALTGARVTNSYVIPGGVRKDITQEIKEMTIKAIAYQRKRLEDWKKIFFYNPSIRARLENVGVMSRENAIKWGAVGPNL
RASGVYYDVRKIEPYGAYDKLDFEIPVYKEGDGLARGLVRLEEIEQSMRILEQIIKNIPEGNILSDRFFKQIPPIRLKKY
WETYRRIVLPGYYASFRPPKGEAISRVEAGRGELAYYVVSDGSPKPYRLRMITPSYRLIYVFKELCKGSRYADLVSIYGS
LDYFPPEADR
>Mature_409_residues
TSQPQNEIQEQLLAATGMSVEFIPVQGELNVGPQHPGSGHMRIFVKLNGDIIEDVDLDVGYVHRAVEKLSENRNYMHLIP
LVERPAILDSIHMNLGYIIAVEKILGVDVPERAQYLRSFAAEVNRIASHLYGLGILAIFLGHSTGFMWGFGDREVWVTIL
EALTGARVTNSYVIPGGVRKDITQEIKEMTIKAIAYQRKRLEDWKKIFFYNPSIRARLENVGVMSRENAIKWGAVGPNLR
ASGVYYDVRKIEPYGAYDKLDFEIPVYKEGDGLARGLVRLEEIEQSMRILEQIIKNIPEGNILSDRFFKQIPPIRLKKYW
ETYRRIVLPGYYASFRPPKGEAISRVEAGRGELAYYVVSDGSPKPYRLRMITPSYRLIYVFKELCKGSRYADLVSIYGSL
DYFPPEADR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758786, Length=385, Percent_Identity=34.025974025974, Blast_Score=222, Evalue=5e-58,
Organism=Homo sapiens, GI260898743, Length=375, Percent_Identity=33.8666666666667, Blast_Score=218, Evalue=1e-56,
Organism=Escherichia coli, GI145693162, Length=386, Percent_Identity=34.1968911917098, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1789076, Length=383, Percent_Identity=29.7650130548303, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1788832, Length=383, Percent_Identity=30.0261096605744, Blast_Score=160, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17555284, Length=388, Percent_Identity=34.5360824742268, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17568379, Length=388, Percent_Identity=34.2783505154639, Blast_Score=235, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24638644, Length=387, Percent_Identity=34.1085271317829, Blast_Score=238, Evalue=5e-63,
Organism=Drosophila melanogaster, GI221459469, Length=384, Percent_Identity=34.375, Blast_Score=231, Evalue=7e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001135
- InterPro:   IPR022885 [H]

Pfam domain/function: PF00346 Complex1_49kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 46775; Mature: 46643

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSQPQNEIQEQLLAATGMSVEFIPVQGELNVGPQHPGSGHMRIFVKLNGDIIEDVDLDV
CCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCEEECCCCCH
GYVHRAVEKLSENRNYMHLIPLVERPAILDSIHMNLGYIIAVEKILGVDVPERAQYLRSF
HHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCHHHEEEHHHHCCCCCHHHHHHHHH
AAEVNRIASHLYGLGILAIFLGHSTGFMWGFGDREVWVTILEALTGARVTNSYVIPGGVR
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHCCCCCCCEECCCCCH
KDITQEIKEMTIKAIAYQRKRLEDWKKIFFYNPSIRARLENVGVMSRENAIKWGAVGPNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHCCCCCCCCCEEECCCCCCC
RASGVYYDVRKIEPYGAYDKLDFEIPVYKEGDGLARGLVRLEEIEQSMRILEQIIKNIPE
CCCCEEEEEEEECCCCCCCCEEEEECEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GNILSDRFFKQIPPIRLKKYWETYRRIVLPGYYASFRPPKGEAISRVEAGRGELAYYVVS
CCCCHHHHHHHCCCHHHHHHHHHHHHEECCCHHHCCCCCCCHHHHHHHCCCCCEEEEEEE
DGSPKPYRLRMITPSYRLIYVFKELCKGSRYADLVSIYGSLDYFPPEADR
CCCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TSQPQNEIQEQLLAATGMSVEFIPVQGELNVGPQHPGSGHMRIFVKLNGDIIEDVDLDV
CCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCEEECCCCCH
GYVHRAVEKLSENRNYMHLIPLVERPAILDSIHMNLGYIIAVEKILGVDVPERAQYLRSF
HHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCHHHEEEHHHHCCCCCHHHHHHHHH
AAEVNRIASHLYGLGILAIFLGHSTGFMWGFGDREVWVTILEALTGARVTNSYVIPGGVR
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHCCCCCCCEECCCCCH
KDITQEIKEMTIKAIAYQRKRLEDWKKIFFYNPSIRARLENVGVMSRENAIKWGAVGPNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHCCCCCCCCCEEECCCCCCC
RASGVYYDVRKIEPYGAYDKLDFEIPVYKEGDGLARGLVRLEEIEQSMRILEQIIKNIPE
CCCCEEEEEEEECCCCCCCCEEEEECEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GNILSDRFFKQIPPIRLKKYWETYRRIVLPGYYASFRPPKGEAISRVEAGRGELAYYVVS
CCCCHHHHHHHCCCHHHHHHHHHHHHEECCCHHHCCCCCCCHHHHHHHCCCCCEEEEEEE
DGSPKPYRLRMITPSYRLIYVFKELCKGSRYADLVSIYGSLDYFPPEADR
CCCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA