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The map label for this gene is thyX

Identifier: 15897261

GI number: 15897261

Start: 274562

End: 275344

Strand: Direct

Name: thyX

Synonym: SSO0321

Alternate gene names: 15897261

Gene position: 274562-275344 (Clockwise)

Preceding gene: 15897259

Following gene: 15897262

Centisome position: 9.18

GC content: 35.38

Gene sequence:

>783_bases
ATGATCTCTGTTAAATTAGTCTCATATACGAATGATGGAGAGAAAGTCATTGCTATTGCTGCTAAGATGAGTAGGAGTAG
AAAAGGTTGGGATTATCATGAGAAAGACATGACTGATGATGAAATTGAGACATGGATCAGAGATGCAATCCTTCACGGTT
ATTGGAGTGTTCTTGAGCATAGCGTTTATACTTTTTCTATAGAAGAAATTTCTCGTGTAGCTTCACATCAGCTTGTGAGG
CATAGGATTGCAAGTTATACGCAAATGAGTCATAGGTTTGCTAAGCCTATAGACGAATACTACAAACCAATTATTCCGCC
ATCTGCCAAGAAAAGAAGTAAAGAGTTAGTGGAGAAAGCGTATAAGGAAGCCTATGACAACTATTACACACTTTTAGAAA
GCGGTGTACCAGAGGAAGATGCAAGATATGTACTACCAAATGGAGTAAATACAAATATTGTCGTCACAATGAATGCTAGA
GAGTTATATAACTTCTTCTCGCTTCGACTGTGTTCAAGGGCACAGTGGGAGATTAGAGCAATAGCTTGGAAAATGTTAGA
GGAGGTTAAGAAAGTTCATCCCCGACTATTCAAATATACTGGACCAAATTGTATAATACATGAAAACTTCATAAGAAATG
AAAATGAATCTATAACTTTAGAAGATATATTTAAAGATTACAAATTAGAGTTCATATCTCAAAGATGCATCGAGGGAGTA
TTGAGAGACGGAATAAAAAAATGCATCATAAATTCGCGTTCTGTATTGGATAATATTAAATAA

Upstream 100 bases:

>100_bases
ATTTTATAAAAGTTATAAGATTATTTTAGATCAATTAAGCTGTCAATAAAACGATGAACCATATTTCTTAAAAATATAAT
AAGAGATAGTAGTATTTGAT

Downstream 100 bases:

>100_bases
CTATAGTATAGGATAGAACTTTTTACTGTAACTCTTTAACGAAGAGTATTTAAATGATTACCTTTTATATACACATGCGA
TGTCATTTACACAAGCTATT

Product: hypothetical protein

Products: NA

Alternate protein names: TS; TSase

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MISVKLVSYTNDGEKVIAIAAKMSRSRKGWDYHEKDMTDDEIETWIRDAILHGYWSVLEHSVYTFSIEEISRVASHQLVR
HRIASYTQMSHRFAKPIDEYYKPIIPPSAKKRSKELVEKAYKEAYDNYYTLLESGVPEEDARYVLPNGVNTNIVVTMNAR
ELYNFFSLRLCSRAQWEIRAIAWKMLEEVKKVHPRLFKYTGPNCIIHENFIRNENESITLEDIFKDYKLEFISQRCIEGV
LRDGIKKCIINSRSVLDNIK

Sequences:

>Translated_260_residues
MISVKLVSYTNDGEKVIAIAAKMSRSRKGWDYHEKDMTDDEIETWIRDAILHGYWSVLEHSVYTFSIEEISRVASHQLVR
HRIASYTQMSHRFAKPIDEYYKPIIPPSAKKRSKELVEKAYKEAYDNYYTLLESGVPEEDARYVLPNGVNTNIVVTMNAR
ELYNFFSLRLCSRAQWEIRAIAWKMLEEVKKVHPRLFKYTGPNCIIHENFIRNENESITLEDIFKDYKLEFISQRCIEGV
LRDGIKKCIINSRSVLDNIK
>Mature_260_residues
MISVKLVSYTNDGEKVIAIAAKMSRSRKGWDYHEKDMTDDEIETWIRDAILHGYWSVLEHSVYTFSIEEISRVASHQLVR
HRIASYTQMSHRFAKPIDEYYKPIIPPSAKKRSKELVEKAYKEAYDNYYTLLESGVPEEDARYVLPNGVNTNIVVTMNAR
ELYNFFSLRLCSRAQWEIRAIAWKMLEEVKKVHPRLFKYTGPNCIIHENFIRNENESITLEDIFKDYKLEFISQRCIEGV
LRDGIKKCIINSRSVLDNIK

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): THYX_SULSO (Q980H6)

Other databases:

- EMBL:   AE006641
- PIR:   A90175
- RefSeq:   NP_341866.1
- ProteinModelPortal:   Q980H6
- SMR:   Q980H6
- GeneID:   1455466
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO0321
- NMPDR:   fig|273057.1.peg.289
- HOGENOM:   HBG458114
- OMA:   TSHQLVR
- ProtClustDB:   CLSK2484412
- BioCyc:   SSOL273057:SSO0321-MONOMER
- BRENDA:   2.1.1.148
- HAMAP:   MF_01408
- InterPro:   IPR003669
- TIGRFAMs:   TIGR02170

Pfam domain/function: PF02511 Thy1; SSF69796 Thy1

EC number: =2.1.1.148

Molecular weight: Translated: 30568; Mature: 30568

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS51331 THYX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVKLVSYTNDGEKVIAIAAKMSRSRKGWDYHEKDMTDDEIETWIRDAILHGYWSVLEH
CEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SVYTFSIEEISRVASHQLVRHRIASYTQMSHRFAKPIDEYYKPIIPPSAKKRSKELVEKA
HHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
YKEAYDNYYTLLESGVPEEDARYVLPNGVNTNIVVTMNARELYNFFSLRLCSRAQWEIRA
HHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCEEEEECHHHHHHHHHHHHHHCCHHHHHH
IAWKMLEEVKKVHPRLFKYTGPNCIIHENFIRNENESITLEDIFKDYKLEFISQRCIEGV
HHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
LRDGIKKCIINSRSVLDNIK
HHHHHHHHHHCCHHHHCCCC
>Mature Secondary Structure
MISVKLVSYTNDGEKVIAIAAKMSRSRKGWDYHEKDMTDDEIETWIRDAILHGYWSVLEH
CEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SVYTFSIEEISRVASHQLVRHRIASYTQMSHRFAKPIDEYYKPIIPPSAKKRSKELVEKA
HHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
YKEAYDNYYTLLESGVPEEDARYVLPNGVNTNIVVTMNARELYNFFSLRLCSRAQWEIRA
HHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCEEEEECHHHHHHHHHHHHHHCCHHHHHH
IAWKMLEEVKKVHPRLFKYTGPNCIIHENFIRNENESITLEDIFKDYKLEFISQRCIEGV
HHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
LRDGIKKCIINSRSVLDNIK
HHHHHHHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726