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The map label for this gene is mpg1 [H]

Identifier: 15897258

GI number: 15897258

Start: 271082

End: 272167

Strand: Direct

Name: mpg1 [H]

Synonym: SSO0317

Alternate gene names: 15897258

Gene position: 271082-272167 (Clockwise)

Preceding gene: 15897257

Following gene: 15897259

Centisome position: 9.06

GC content: 32.6

Gene sequence:

>1086_bases
ATGGTATCCGCAATTGTACTAGCTGGAGGTTATGCTACTAGACTTAGGCCTTTAAGTTTGACTAAACCGAAAGCTCTTTT
CCCCATTTTAAACAAACCTATACTGGGTTACATTTTGGAAAGTCTTATCAATTCCGATGTTAGTGATATATATTTATCAT
TAAGAGTAATGGCTGACAAGATAATCGATTACTTAAAGGATACTAGCATGCTAGATAAGGTTAAGATAGAAGTTGAAAGT
GAACCTTTAGGTGATGCAGGACCTTTAAAATTGATCTCCCAGAAGTATAATTTAGATGATGACGTTTTGGTCATATATGG
AGATATATATAGTGAGATAAATATAAAATCCCTTCTCGATTTTTATTATAAAAAGAGTTGTGATGCAGTAGTAGTTGGTA
CGGAAGTTGAAGATCCGAGAAGATATGGTGTACTTTATACAGAAAATGATGTCTTAGTAGAGTTAATAGAAAAACCTAAA
AAACCTATAAGCAATTTGATTAACGGAGGAGTATATATTTTTAAAAAGGATCTATTCAAGTTAGTAGAAACTCCATCTTC
TATTAGTAAGGATTTTTTACCTAAGCTACTTAGAACTAAGTCCATTTCAGTGTATAAATATCACGGGATATGGGCAGATA
TAGGAGTCCCAGACGACTATCTTAGACTCAATTTTGAAGTATTAGTACAGAAATACCCTAAGGGTTATATAAACTCGTCA
GCTAAGGTCAGTGAAAAATCTACGCTTATTCCGCCCTATTATATTGGTTCGAAAAATGTTATTGGAGAGGATGCATATAT
TACCTCTAATACTATTTTGGGTAATGATGTAGAAATAGGAAAAGGAACATACATATCTGAGAGTATACTAATGAATAAAG
TGCAAGTTAAAGAATATACATATATCTCAGGATCTATAATAGCTGACAAAACTAAGATAGGGAGATGGAATCATATATTA
GATGGGTCTATTTTAGGTGAAGAGGTAATTACTAGCGATGGAGTACTTATAAATCGACGTACGATAATCTTGCCTAATAA
GGAAGTGAAGGAACACGTTTATGATAAAGGCAAAATAATACTATAA

Upstream 100 bases:

>100_bases
GCTTGGTGGAATGTAGTAAATTGGGATGCAGCGGAAAAGAAGTTACAGAAATATTTAACGAAGTAAATAGTTTTTTATCT
ATTATCGCATTTTTCTTAGT

Downstream 100 bases:

>100_bases
GGTGACAATTATGATCCTTAGGGAAATTATTGACGAATTGTCATATCAGTTGAAGCAAAGAAGAATTATTAACGTATGTG
TTAGCCCTGCTTACACATCA

Product: sugar phosphate nucleotydyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MVSAIVLAGGYATRLRPLSLTKPKALFPILNKPILGYILESLINSDVSDIYLSLRVMADKIIDYLKDTSMLDKVKIEVES
EPLGDAGPLKLISQKYNLDDDVLVIYGDIYSEINIKSLLDFYYKKSCDAVVVGTEVEDPRRYGVLYTENDVLVELIEKPK
KPISNLINGGVYIFKKDLFKLVETPSSISKDFLPKLLRTKSISVYKYHGIWADIGVPDDYLRLNFEVLVQKYPKGYINSS
AKVSEKSTLIPPYYIGSKNVIGEDAYITSNTILGNDVEIGKGTYISESILMNKVQVKEYTYISGSIIADKTKIGRWNHIL
DGSILGEEVITSDGVLINRRTIILPNKEVKEHVYDKGKIIL

Sequences:

>Translated_361_residues
MVSAIVLAGGYATRLRPLSLTKPKALFPILNKPILGYILESLINSDVSDIYLSLRVMADKIIDYLKDTSMLDKVKIEVES
EPLGDAGPLKLISQKYNLDDDVLVIYGDIYSEINIKSLLDFYYKKSCDAVVVGTEVEDPRRYGVLYTENDVLVELIEKPK
KPISNLINGGVYIFKKDLFKLVETPSSISKDFLPKLLRTKSISVYKYHGIWADIGVPDDYLRLNFEVLVQKYPKGYINSS
AKVSEKSTLIPPYYIGSKNVIGEDAYITSNTILGNDVEIGKGTYISESILMNKVQVKEYTYISGSIIADKTKIGRWNHIL
DGSILGEEVITSDGVLINRRTIILPNKEVKEHVYDKGKIIL
>Mature_361_residues
MVSAIVLAGGYATRLRPLSLTKPKALFPILNKPILGYILESLINSDVSDIYLSLRVMADKIIDYLKDTSMLDKVKIEVES
EPLGDAGPLKLISQKYNLDDDVLVIYGDIYSEINIKSLLDFYYKKSCDAVVVGTEVEDPRRYGVLYTENDVLVELIEKPK
KPISNLINGGVYIFKKDLFKLVETPSSISKDFLPKLLRTKSISVYKYHGIWADIGVPDDYLRLNFEVLVQKYPKGYINSS
AKVSEKSTLIPPYYIGSKNVIGEDAYITSNTILGNDVEIGKGTYISESILMNKVQVKEYTYISGSIIADKTKIGRWNHIL
DGSILGEEVITSDGVLINRRTIILPNKEVKEHVYDKGKIIL

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=361, Percent_Identity=29.0858725761773, Blast_Score=178, Evalue=8e-45,
Organism=Homo sapiens, GI11761619, Length=388, Percent_Identity=27.319587628866, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI31881779, Length=385, Percent_Identity=24.1558441558442, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI45447090, Length=385, Percent_Identity=24.1558441558442, Blast_Score=96, Evalue=7e-20,
Organism=Escherichia coli, GI1788351, Length=193, Percent_Identity=30.5699481865285, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790224, Length=178, Percent_Identity=30.3370786516854, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI133931050, Length=368, Percent_Identity=29.0760869565217, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI17509979, Length=334, Percent_Identity=26.3473053892216, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17509981, Length=324, Percent_Identity=25.6172839506173, Blast_Score=88, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6320148, Length=364, Percent_Identity=31.043956043956, Blast_Score=183, Evalue=4e-47,
Organism=Drosophila melanogaster, GI21355443, Length=360, Percent_Identity=32.7777777777778, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24644084, Length=360, Percent_Identity=32.7777777777778, Blast_Score=186, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 40520; Mature: 40520

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSAIVLAGGYATRLRPLSLTKPKALFPILNKPILGYILESLINSDVSDIYLSLRVMADK
CCEEEEEECCCHHHEEECCCCCCCHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
IIDYLKDTSMLDKVKIEVESEPLGDAGPLKLISQKYNLDDDVLVIYGDIYSEINIKSLLD
HHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCCCCEEEEEECHHCCCCHHHHHH
FYYKKSCDAVVVGTEVEDPRRYGVLYTENDVLVELIEKPKKPISNLINGGVYIFKKDLFK
HHHHCCCCEEEEECCCCCCHHEEEEEECCHHHHHHHHCCHHHHHHHHCCCEEEEHHHHHH
LVETPSSISKDFLPKLLRTKSISVYKYHGIWADIGVPDDYLRLNFEVLVQKYPKGYINSS
HHCCCHHHHHHHHHHHHHHCCCEEEEEECEEEECCCCCHHHEEHHHHHHHHCCCCCCCCC
AKVSEKSTLIPPYYIGSKNVIGEDAYITSNTILGNDVEIGKGTYISESILMNKVQVKEYT
CCCCCCCCCCCCEEECCCCCCCCCCEEECCEEECCCEECCCCCEEHHHHHHHHEEEEEEE
YISGSIIADKTKIGRWNHILDGSILGEEVITSDGVLINRRTIILPNKEVKEHVYDKGKII
EECCEEEECCCCCCCCCEECCCCHHCHHHHCCCCEEEECEEEEECCHHHHHHHHCCCCEE
L
C
>Mature Secondary Structure
MVSAIVLAGGYATRLRPLSLTKPKALFPILNKPILGYILESLINSDVSDIYLSLRVMADK
CCEEEEEECCCHHHEEECCCCCCCHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
IIDYLKDTSMLDKVKIEVESEPLGDAGPLKLISQKYNLDDDVLVIYGDIYSEINIKSLLD
HHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCCCCEEEEEECHHCCCCHHHHHH
FYYKKSCDAVVVGTEVEDPRRYGVLYTENDVLVELIEKPKKPISNLINGGVYIFKKDLFK
HHHHCCCCEEEEECCCCCCHHEEEEEECCHHHHHHHHCCHHHHHHHHCCCEEEEHHHHHH
LVETPSSISKDFLPKLLRTKSISVYKYHGIWADIGVPDDYLRLNFEVLVQKYPKGYINSS
HHCCCHHHHHHHHHHHHHHCCCEEEEEECEEEECCCCCHHHEEHHHHHHHHCCCCCCCCC
AKVSEKSTLIPPYYIGSKNVIGEDAYITSNTILGNDVEIGKGTYISESILMNKVQVKEYT
CCCCCCCCCCCCEEECCCCCCCCCCEEECCEEECCCEECCCCCEEHHHHHHHHEEEEEEE
YISGSIIADKTKIGRWNHILDGSILGEEVITSDGVLINRRTIILPNKEVKEHVYDKGKII
EECCEEEECCCCCCCCCEECCCCHHCHHHHCCCCEEEECEEEEECCHHHHHHHHCCCCEE
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]