| Definition | Sulfolobus solfataricus P2 chromosome, complete genome. |
|---|---|
| Accession | NC_002754 |
| Length | 2,992,245 |
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The map label for this gene is hit
Identifier: 15897193
GI number: 15897193
Start: 215580
End: 216095
Strand: Reverse
Name: hit
Synonym: SSO0249
Alternate gene names: NA
Gene position: 216095-215580 (Counterclockwise)
Preceding gene: 15897194
Following gene: 15897192
Centisome position: 7.22
GC content: 34.88
Gene sequence:
>516_bases ATGGATATTTTATGGGCACCATGGAGAGCTAAATATATTTCTGAAACTAGCAAGGTAAAACAAGATGAATGCTTATTTTG TAGAGTAATAAAAGAAGAAAATGACGAACAAAATTACATAGTATATAGAGGAAAACACGCTTTTATAATACTCAACGCTT TTCCCTATAATACCGCTCATGTGATGGTTGTTCCTTACAGACACGTCCCTTCAGTTGAGCTTTTAAGTAATGATGAGGCA TTAGACATATTTACTTTATCTACTATTGCAATAAGAGCTATAAGAGATATTTATGCTCCAGACGGTTTTAATATAGGCGT AAACATAGGTAGAGTGGCAGGAGCAGGTATAGAATCTCATATTCACGTTCATATCGTGCCGAGATGGAATGGTGATTCCA ATTTTATGCCGGTCATTTTTAACACTAAGGTCATGCCAGAAACACTCAGCGATACGTTTAAAAAATTAAATACAAAAGTT AATGAGATTATGAAGAAGCCCTCGAGATCTGAGTAA
Upstream 100 bases:
>100_bases GCCAGAAGGAGAAGTAGTGTTTGCATTAACTGAAGAAGGAATAAGGGATGCGGAAGAGTAAAAGTTAATATTTTATGTGT TATTATAGTCTATTTTACTT
Downstream 100 bases:
>100_bases TTGATGAAGGCAGGGTTTTACAGATGAATTACTTAGAATATTTTGATAGAATTAGACTAGCAAAAGAGAAAATAGAAAAA TATGTGCATATTACTCCAAT
Product: HIT-like protein
Products: NA
Alternate protein names: ATP adenylyltransferase; Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase; AP,A phosphorylase [H]
Number of amino acids: Translated: 171; Mature: 171
Protein sequence:
>171_residues MDILWAPWRAKYISETSKVKQDECLFCRVIKEENDEQNYIVYRGKHAFIILNAFPYNTAHVMVVPYRHVPSVELLSNDEA LDIFTLSTIAIRAIRDIYAPDGFNIGVNIGRVAGAGIESHIHVHIVPRWNGDSNFMPVIFNTKVMPETLSDTFKKLNTKV NEIMKKPSRSE
Sequences:
>Translated_171_residues MDILWAPWRAKYISETSKVKQDECLFCRVIKEENDEQNYIVYRGKHAFIILNAFPYNTAHVMVVPYRHVPSVELLSNDEA LDIFTLSTIAIRAIRDIYAPDGFNIGVNIGRVAGAGIESHIHVHIVPRWNGDSNFMPVIFNTKVMPETLSDTFKKLNTKV NEIMKKPSRSE >Mature_171_residues MDILWAPWRAKYISETSKVKQDECLFCRVIKEENDEQNYIVYRGKHAFIILNAFPYNTAHVMVVPYRHVPSVELLSNDEA LDIFTLSTIAIRAIRDIYAPDGFNIGVNIGRVAGAGIESHIHVHIVPRWNGDSNFMPVIFNTKVMPETLSDTFKKLNTKV NEIMKKPSRSE
Specific function: Catabolizes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) into ADP and ATP. It does not catalyze the reverse phosphorolysis reaction. The optimum substrates are dinucleoside polyphosphates containing four or five phosphate residues [H]
COG id: COG0537
COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HIT domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011146 - InterPro: IPR011151 - InterPro: IPR001310 [H]
Pfam domain/function: PF01230 HIT [H]
EC number: =2.7.7.53 [H]
Molecular weight: Translated: 19593; Mature: 19593
Theoretical pI: Translated: 7.67; Mature: 7.67
Prosite motif: PS00133 CARBOXYPEPT_ZN_2 ; PS51084 HIT_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDILWAPWRAKYISETSKVKQDECLFCRVIKEENDEQNYIVYRGKHAFIILNAFPYNTAH CCEEECCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCEEEEEEEECCCCCEE VMVVPYRHVPSVELLSNDEALDIFTLSTIAIRAIRDIYAPDGFNIGVNIGRVAGAGIESH EEEEECCCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHCCCCCEECEEECCEECCCCCCE IHVHIVPRWNGDSNFMPVIFNTKVMPETLSDTFKKLNTKVNEIMKKPSRSE EEEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCC >Mature Secondary Structure MDILWAPWRAKYISETSKVKQDECLFCRVIKEENDEQNYIVYRGKHAFIILNAFPYNTAH CCEEECCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCEEEEEEEECCCCCEE VMVVPYRHVPSVELLSNDEALDIFTLSTIAIRAIRDIYAPDGFNIGVNIGRVAGAGIESH EEEEECCCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHCCCCCEECEEECCEECCCCCCE IHVHIVPRWNGDSNFMPVIFNTKVMPETLSDTFKKLNTKVNEIMKKPSRSE EEEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9634230; 12368430; 12218036 [H]