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The map label for this gene is tdcB [H]

Identifier: 15897192

GI number: 15897192

Start: 214339

End: 215556

Strand: Reverse

Name: tdcB [H]

Synonym: SSO0248

Alternate gene names: 15897192

Gene position: 215556-214339 (Counterclockwise)

Preceding gene: 15897193

Following gene: 15897191

Centisome position: 7.2

GC content: 34.15

Gene sequence:

>1218_bases
ATGAATTACTTAGAATATTTTGATAGAATTAGACTAGCAAAAGAGAAAATAGAAAAATATGTGCATATTACTCCAATAGA
TTATTCTACAACGTTTTCCAGAATTATAAACGCAAAAGTTTATCTTAAGTTGGAAAATCTACAGAAAACTGGATCATTCA
AAGTTAGAGGTGCCTTTAATAAGTTATTATCTTTAAAGGAGGAAGAAAAAAAGAATGGCGTTATTGCAGTTTCAGCAGGT
AATCATGCTCAAGGAGTTGCTTATGCAGCCTCCACGTTAAATATCAAATCGACTATAGTGATGCCAGAAACAGCTCCAGC
TTCCAAGTATTTAGCTACAAAATCCTATGGGGCAGAAGTAGTTCTTTATGGTAAGTACTTGCATGAGAGTATGAAGAAAG
CGGAAGAATTGATTCAAAATACTGGTTTAATATTTGTTCATCCTTATAGTGATTTAGATGTGATAACGGGTCAAGGTACC
ATAGGATTAGAATTGTATGATATCGAACCAGATTACGTAATTATTCCAATAGGGGGTGGAGGATTGATTTCTGGTATAAG
TATAGCTTTAAAGTATAGATTCCCAAACGTCAAGATAATAGGCGTTCAGTCTTCTTCTTCTCCTTCAATGAAGGTTTCTA
AGGATCTTGGGAGGCTTGTAGAAATAGAGCCTAGTTATTCCATAGCTGATGGCATATTGGTTAAGTCTCCTTCTGAATTA
ACCTTTAGTATAATTAATGAGTTAGTAGATGATATAGTATTAGTGGATGATGAAGAAATAGCTGAGGCAATAGTTTTACT
ACTTGAAAGAAGTAAAACGCTAGCAGAAGGAGCAGGAGCTGCAGCATTAGCGTCACTAATTTCAGGGAAGGTTAAAGTAA
ATGGAATAGACAAAAAAGTAATTTCATTAGTAAGTGGGGGAAATATTGACTTATCATTATTGTCTACTCTAACAGAGAAG
TTTTTATATAGACAAAAAAGGGTAGTCAAAGTGAGGGTAATAGTTCCAGATAAGCCAGGACAGTTAAATAAAGTATTAAG
CTATGTAGTTAAGATCAGAGGTAATATAATAGATATTGTTCATGATAGGCACAGTAGTGATGTATTGCCTGGATACACTA
AAATATATATAACTTTCGAGCTTCAGTCTTCAGAGGCTATTACCTTACTTCTGACAAATCTGGCAAACGAGGGAATAGAC
GTGAAAATTGTAGAATAG

Upstream 100 bases:

>100_bases
AAACACTCAGCGATACGTTTAAAAAATTAAATACAAAAGTTAATGAGATTATGAAGAAGCCCTCGAGATCTGAGTAATTG
ATGAAGGCAGGGTTTTACAG

Downstream 100 bases:

>100_bases
TTTATAAGTCTTCTATGTAGAGATTTAGGTGGTAGATGCGGATGGAATTTATTATTTAGGTCCAGAGGGAAGTTTTACAC
ACGAAGCAGCTAGTTTGTTT

Product: threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MNYLEYFDRIRLAKEKIEKYVHITPIDYSTTFSRIINAKVYLKLENLQKTGSFKVRGAFNKLLSLKEEEKKNGVIAVSAG
NHAQGVAYAASTLNIKSTIVMPETAPASKYLATKSYGAEVVLYGKYLHESMKKAEELIQNTGLIFVHPYSDLDVITGQGT
IGLELYDIEPDYVIIPIGGGGLISGISIALKYRFPNVKIIGVQSSSSPSMKVSKDLGRLVEIEPSYSIADGILVKSPSEL
TFSIINELVDDIVLVDDEEIAEAIVLLLERSKTLAEGAGAAALASLISGKVKVNGIDKKVISLVSGGNIDLSLLSTLTEK
FLYRQKRVVKVRVIVPDKPGQLNKVLSYVVKIRGNIIDIVHDRHSSDVLPGYTKIYITFELQSSEAITLLLTNLANEGID
VKIVE

Sequences:

>Translated_405_residues
MNYLEYFDRIRLAKEKIEKYVHITPIDYSTTFSRIINAKVYLKLENLQKTGSFKVRGAFNKLLSLKEEEKKNGVIAVSAG
NHAQGVAYAASTLNIKSTIVMPETAPASKYLATKSYGAEVVLYGKYLHESMKKAEELIQNTGLIFVHPYSDLDVITGQGT
IGLELYDIEPDYVIIPIGGGGLISGISIALKYRFPNVKIIGVQSSSSPSMKVSKDLGRLVEIEPSYSIADGILVKSPSEL
TFSIINELVDDIVLVDDEEIAEAIVLLLERSKTLAEGAGAAALASLISGKVKVNGIDKKVISLVSGGNIDLSLLSTLTEK
FLYRQKRVVKVRVIVPDKPGQLNKVLSYVVKIRGNIIDIVHDRHSSDVLPGYTKIYITFELQSSEAITLLLTNLANEGID
VKIVE
>Mature_405_residues
MNYLEYFDRIRLAKEKIEKYVHITPIDYSTTFSRIINAKVYLKLENLQKTGSFKVRGAFNKLLSLKEEEKKNGVIAVSAG
NHAQGVAYAASTLNIKSTIVMPETAPASKYLATKSYGAEVVLYGKYLHESMKKAEELIQNTGLIFVHPYSDLDVITGQGT
IGLELYDIEPDYVIIPIGGGGLISGISIALKYRFPNVKIIGVQSSSSPSMKVSKDLGRLVEIEPSYSIADGILVKSPSEL
TFSIINELVDDIVLVDDEEIAEAIVLLLERSKTLAEGAGAAALASLISGKVKVNGIDKKVISLVSGGNIDLSLLSTLTEK
FLYRQKRVVKVRVIVPDKPGQLNKVLSYVVKIRGNIIDIVHDRHSSDVLPGYTKIYITFELQSSEAITLLLTNLANEGID
VKIVE

Specific function: Acts on both serine and threonine, and properly considered as a hydroxy amino acid deaminase [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=320, Percent_Identity=38.4375, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI33469958, Length=311, Percent_Identity=29.2604501607717, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI19923959, Length=307, Percent_Identity=28.3387622149837, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789505, Length=315, Percent_Identity=47.3015873015873, Blast_Score=242, Evalue=3e-65,
Organism=Escherichia coli, GI1790207, Length=329, Percent_Identity=34.6504559270517, Blast_Score=182, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI71991565, Length=393, Percent_Identity=36.8956743002545, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17537387, Length=360, Percent_Identity=35.5555555555556, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17508781, Length=316, Percent_Identity=28.4810126582279, Blast_Score=127, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6322631, Length=307, Percent_Identity=39.0879478827362, Blast_Score=192, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6320930, Length=412, Percent_Identity=31.7961165048544, Blast_Score=174, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6319788, Length=271, Percent_Identity=26.5682656826568, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21355833, Length=346, Percent_Identity=39.8843930635838, Blast_Score=182, Evalue=5e-46,
Organism=Drosophila melanogaster, GI24645328, Length=266, Percent_Identity=36.4661654135338, Blast_Score=113, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005789 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 44364; Mature: 44364

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYLEYFDRIRLAKEKIEKYVHITPIDYSTTFSRIINAKVYLKLENLQKTGSFKVRGAFN
CCHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHCEEEEEEEECCCCCCCEEEEEHHH
KLLSLKEEEKKNGVIAVSAGNHAQGVAYAASTLNIKSTIVMPETAPASKYLATKSYGAEV
HHHHCHHHHCCCCEEEEECCCCCCCEEEEEEEEEEEEEEEECCCCCCHHHEEECCCCCEE
VLYGKYLHESMKKAEELIQNTGLIFVHPYSDLDVITGQGTIGLELYDIEPDYVIIPIGGG
EEEHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCEEEEEEEEECCCEEEEEECCC
GLISGISIALKYRFPNVKIIGVQSSSSPSMKVSKDLGRLVEIEPSYSIADGILVKSPSEL
CHHCCEEEEEEEECCCEEEEEEECCCCCCEEEHHCCCCEEEECCCCCCCCCEEEECCCHH
TFSIINELVDDIVLVDDEEIAEAIVLLLERSKTLAEGAGAAALASLISGKVKVNGIDKKV
HHHHHHHHHHHEEEECCHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHCCCEEEECCCHHH
ISLVSGGNIDLSLLSTLTEKFLYRQKRVVKVRVIVPDKPGQLNKVLSYVVKIRGNIIDIV
HHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEE
HDRHSSDVLPGYTKIYITFELQSSEAITLLLTNLANEGIDVKIVE
ECCCCCCCCCCEEEEEEEEEECCCCEEEEEEEHHCCCCCEEEEEC
>Mature Secondary Structure
MNYLEYFDRIRLAKEKIEKYVHITPIDYSTTFSRIINAKVYLKLENLQKTGSFKVRGAFN
CCHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHCEEEEEEEECCCCCCCEEEEEHHH
KLLSLKEEEKKNGVIAVSAGNHAQGVAYAASTLNIKSTIVMPETAPASKYLATKSYGAEV
HHHHCHHHHCCCCEEEEECCCCCCCEEEEEEEEEEEEEEEECCCCCCHHHEEECCCCCEE
VLYGKYLHESMKKAEELIQNTGLIFVHPYSDLDVITGQGTIGLELYDIEPDYVIIPIGGG
EEEHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCEEEEEEEEECCCEEEEEECCC
GLISGISIALKYRFPNVKIIGVQSSSSPSMKVSKDLGRLVEIEPSYSIADGILVKSPSEL
CHHCCEEEEEEEECCCEEEEEEECCCCCCEEEHHCCCCEEEECCCCCCCCCEEEECCCHH
TFSIINELVDDIVLVDDEEIAEAIVLLLERSKTLAEGAGAAALASLISGKVKVNGIDKKV
HHHHHHHHHHHEEEECCHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHCCCEEEECCCHHH
ISLVSGGNIDLSLLSTLTEKFLYRQKRVVKVRVIVPDKPGQLNKVLSYVVKIRGNIIDIV
HHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEE
HDRHSSDVLPGYTKIYITFELQSSEAITLLLTNLANEGIDVKIVE
ECCCCCCCCCCEEEEEEEEEECCCCEEEEEEEHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA