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The map label for this gene is ndk [H]

Identifier: 15897176

GI number: 15897176

Start: 198996

End: 199412

Strand: Reverse

Name: ndk [H]

Synonym: SSO0230

Alternate gene names: 15897176

Gene position: 199412-198996 (Counterclockwise)

Preceding gene: 15897177

Following gene: 15897174

Centisome position: 6.66

GC content: 37.65

Gene sequence:

>417_bases
ATGGTTGCACAAAGAACATTTGTAATGATAAAGCCAGATGGAGTTAAGAGGGGATTAATAGGCGAGATAATTAGTAGATT
TGAGAAAAGGGGATTAAAAATTGTATCTCTTAAAATGGTGAAAATGTCAAGGGACACAGCTGAAAAATTGTATGAGGAGC
ACAAAGGAAAAAGTTTCTTTGAAGAACTTGTAAATTACGTGACCTCTGGTCCAGTAGTATGCATGGTGATAGAAGGCGAT
GACGTAGTGCAAGTGATAAGGCGAATGATTGGTAATACAGATCCTAAAGAGGCACCTCCTGGCACTATAAGAGGAGATTA
TGCGTTATCTAAGTCAGAAAACGTCATTCATGCATCTGATTCTATTGAAAAAGCTCAGCGAGAGATGTCGTTATTCTTCG
ATAAATCAGATCTGTAA

Upstream 100 bases:

>100_bases
GTGGTTTTGTTCAAGTAAGTGTAGGAAATCAATGCTGAAGTATCATAGAGATCCAAAGAAGTATAAATGGACTACTAGAT
ATATGAAGGTTCGATGAAAA

Downstream 100 bases:

>100_bases
TCCTAATCCATATAAAGGATCTTCTTTTCTCTTTATTCTTATTATTTCTTTTATTACTTCCCTCATATCATCTGTAATAG
AACTTGGATACTTGTTGACT

Product: nucleoside diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase [H]

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MVAQRTFVMIKPDGVKRGLIGEIISRFEKRGLKIVSLKMVKMSRDTAEKLYEEHKGKSFFEELVNYVTSGPVVCMVIEGD
DVVQVIRRMIGNTDPKEAPPGTIRGDYALSKSENVIHASDSIEKAQREMSLFFDKSDL

Sequences:

>Translated_138_residues
MVAQRTFVMIKPDGVKRGLIGEIISRFEKRGLKIVSLKMVKMSRDTAEKLYEEHKGKSFFEELVNYVTSGPVVCMVIEGD
DVVQVIRRMIGNTDPKEAPPGTIRGDYALSKSENVIHASDSIEKAQREMSLFFDKSDL
>Mature_138_residues
MVAQRTFVMIKPDGVKRGLIGEIISRFEKRGLKIVSLKMVKMSRDTAEKLYEEHKGKSFFEELVNYVTSGPVVCMVIEGD
DVVQVIRRMIGNTDPKEAPPGTIRGDYALSKSENVIHASDSIEKAQREMSLFFDKSDL

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate [H]

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family [H]

Homologues:

Organism=Homo sapiens, GI37693993, Length=135, Percent_Identity=49.6296296296296, Blast_Score=152, Evalue=9e-38,
Organism=Homo sapiens, GI4826862, Length=135, Percent_Identity=51.1111111111111, Blast_Score=152, Evalue=9e-38,
Organism=Homo sapiens, GI38045913, Length=136, Percent_Identity=49.2647058823529, Blast_Score=147, Evalue=2e-36,
Organism=Homo sapiens, GI4557797, Length=136, Percent_Identity=49.2647058823529, Blast_Score=147, Evalue=3e-36,
Organism=Homo sapiens, GI66392227, Length=135, Percent_Identity=48.1481481481481, Blast_Score=145, Evalue=1e-35,
Organism=Homo sapiens, GI66392205, Length=135, Percent_Identity=48.1481481481481, Blast_Score=145, Evalue=1e-35,
Organism=Homo sapiens, GI4505409, Length=135, Percent_Identity=48.1481481481481, Blast_Score=145, Evalue=1e-35,
Organism=Homo sapiens, GI66392192, Length=135, Percent_Identity=48.1481481481481, Blast_Score=145, Evalue=1e-35,
Organism=Homo sapiens, GI66392203, Length=135, Percent_Identity=48.1481481481481, Blast_Score=145, Evalue=1e-35,
Organism=Homo sapiens, GI37574614, Length=140, Percent_Identity=35, Blast_Score=90, Evalue=5e-19,
Organism=Homo sapiens, GI7019465, Length=140, Percent_Identity=35, Blast_Score=90, Evalue=6e-19,
Organism=Homo sapiens, GI5031951, Length=134, Percent_Identity=31.3432835820896, Blast_Score=88, Evalue=2e-18,
Organism=Homo sapiens, GI30023828, Length=135, Percent_Identity=32.5925925925926, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI4505413, Length=134, Percent_Identity=30.5970149253731, Blast_Score=69, Evalue=1e-12,
Organism=Homo sapiens, GI148839372, Length=136, Percent_Identity=27.9411764705882, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1788866, Length=138, Percent_Identity=46.3768115942029, Blast_Score=139, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17506807, Length=135, Percent_Identity=47.4074074074074, Blast_Score=144, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71995094, Length=134, Percent_Identity=33.5820895522388, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322783, Length=136, Percent_Identity=47.7941176470588, Blast_Score=148, Evalue=4e-37,
Organism=Drosophila melanogaster, GI45549037, Length=135, Percent_Identity=49.6296296296296, Blast_Score=155, Evalue=5e-39,
Organism=Drosophila melanogaster, GI18860097, Length=135, Percent_Identity=30.3703703703704, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24645457, Length=136, Percent_Identity=30.1470588235294, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001564
- InterPro:   IPR023005 [H]

Pfam domain/function: PF00334 NDK [H]

EC number: =2.7.4.6 [H]

Molecular weight: Translated: 15554; Mature: 15554

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00469 NDP_KINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAQRTFVMIKPDGVKRGLIGEIISRFEKRGLKIVSLKMVKMSRDTAEKLYEEHKGKSFF
CCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCHHHH
EELVNYVTSGPVVCMVIEGDDVVQVIRRMIGNTDPKEAPPGTIRGDYALSKSENVIHASD
HHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCEEECCH
SIEKAQREMSLFFDKSDL
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVAQRTFVMIKPDGVKRGLIGEIISRFEKRGLKIVSLKMVKMSRDTAEKLYEEHKGKSFF
CCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCHHHH
EELVNYVTSGPVVCMVIEGDDVVQVIRRMIGNTDPKEAPPGTIRGDYALSKSENVIHASD
HHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCEEECCH
SIEKAQREMSLFFDKSDL
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA