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The map label for this gene is lysK [H]

Identifier: 15897112

GI number: 15897112

Start: 134541

End: 135581

Strand: Direct

Name: lysK [H]

Synonym: SSO0162

Alternate gene names: 15897112

Gene position: 134541-135581 (Clockwise)

Preceding gene: 15897111

Following gene: 15897113

Centisome position: 4.5

GC content: 33.53

Gene sequence:

>1041_bases
ATGCTACAAGAAAAGGAATTAGTGAAACAGAAAGCAAAAGAGTTGCTTCTTGATCTTTTATCAATATACACACCGTCAAA
GAGTGAAGCAAACGCTACAAAATTCTTTGAGAAAATTTCCAAGGACTTAAACCTTAAACTTGAGATTCTACCAGACTCAA
ATTCATTTATACTAGGAGAAGGAGATATACTGTTAGCGTCTCACGTAGATACTGTTTATGGGTATATTGAACCAAAGATA
GAAAACGAACTAATCTATGGGAGAGGCGCAGTAGACGCCAAAGGTCCATTAATAAGTATGATAATAGCTACATGGCTACT
TAATGAGAAAGGAATAAAAGTTAGGGTAAGCGGATTAGCAGATGAGGAAAGTACGAGTATAGGAGCTAAAGAACTTATAG
CGAAAAATTACAATTTTAAATATATAATTGTGGGAGAACCATCGAATGCTACTGATATAGTAGTAGAGTACAGAGGATCA
ATACAACTAGATATAATGTGTGAAGGTACTCCGGAACACTCTTCGTCAGCTAAGAACAATCTGATCGTGGACATTTCTAA
AAAGATAATTGAAGTTTATAAACAGCCTGAAAACTACGATAAACCATCAATAGTACCAACAATAATCCGTGCAGGAGAGT
CTTATAATGTCACACCAGCAAAATTATATCTACATTTGGATATAAGATATGCAATAAATAATAAGAGAGAAGATTTAATC
AAAGAGATCACCGACAAATTTCCAGAATGTAATCTTAAAATAGTTGATGAAACGCCGCCAGTAAAAGTAAGTATAAATAA
TCCAGTAGTAAAGTCCTTAGCTAGGGCGTTATTAAAACAAAATATAAAGCCAAGACTGGTTAAAAAAGCAGGAACAAGTG
ACATGAATATATTGCAGAGGATAACAACAAATATAGCAACATATGGTCCTGGAAATTCTATGCTAGAACATACTACTCAA
GAAAAAATTAGCTTGGATGAAATATATATAGGAGTAAAAACTTATATGTTGGCAATAGAAGAGCTATGGCAAAAGATCTA
A

Upstream 100 bases:

>100_bases
TTACAAGATGAGAAGGTATTATCATTAAAAGCAGGACTTACAACAATAAGATTCCTACCTCCGTATTTAATAACTCAATC
AGATATGGAGTGGGCTTCAG

Downstream 100 bases:

>100_bases
CTAGAGGCCTTCTCTTTAAGCCTATTTATAAACTGTATGAGTTAGTATTATGGAATCAGATTCGTAATGGTCCATTGCCA
GATCACGTGGGAATTATACC

Product: acetyl-lysine deacetylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MLQEKELVKQKAKELLLDLLSIYTPSKSEANATKFFEKISKDLNLKLEILPDSNSFILGEGDILLASHVDTVYGYIEPKI
ENELIYGRGAVDAKGPLISMIIATWLLNEKGIKVRVSGLADEESTSIGAKELIAKNYNFKYIIVGEPSNATDIVVEYRGS
IQLDIMCEGTPEHSSSAKNNLIVDISKKIIEVYKQPENYDKPSIVPTIIRAGESYNVTPAKLYLHLDIRYAINNKREDLI
KEITDKFPECNLKIVDETPPVKVSINNPVVKSLARALLKQNIKPRLVKKAGTSDMNILQRITTNIATYGPGNSMLEHTTQ
EKISLDEIYIGVKTYMLAIEELWQKI

Sequences:

>Translated_346_residues
MLQEKELVKQKAKELLLDLLSIYTPSKSEANATKFFEKISKDLNLKLEILPDSNSFILGEGDILLASHVDTVYGYIEPKI
ENELIYGRGAVDAKGPLISMIIATWLLNEKGIKVRVSGLADEESTSIGAKELIAKNYNFKYIIVGEPSNATDIVVEYRGS
IQLDIMCEGTPEHSSSAKNNLIVDISKKIIEVYKQPENYDKPSIVPTIIRAGESYNVTPAKLYLHLDIRYAINNKREDLI
KEITDKFPECNLKIVDETPPVKVSINNPVVKSLARALLKQNIKPRLVKKAGTSDMNILQRITTNIATYGPGNSMLEHTTQ
EKISLDEIYIGVKTYMLAIEELWQKI
>Mature_346_residues
MLQEKELVKQKAKELLLDLLSIYTPSKSEANATKFFEKISKDLNLKLEILPDSNSFILGEGDILLASHVDTVYGYIEPKI
ENELIYGRGAVDAKGPLISMIIATWLLNEKGIKVRVSGLADEESTSIGAKELIAKNYNFKYIIVGEPSNATDIVVEYRGS
IQLDIMCEGTPEHSSSAKNNLIVDISKKIIEVYKQPENYDKPSIVPTIIRAGESYNVTPAKLYLHLDIRYAINNKREDLI
KEITDKFPECNLKIVDETPPVKVSINNPVVKSLARALLKQNIKPRLVKKAGTSDMNILQRITTNIATYGPGNSMLEHTTQ
EKISLDEIYIGVKTYMLAIEELWQKI

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fifth step. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. LysK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR010175
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: 3.5.1.-

Molecular weight: Translated: 38810; Mature: 38810

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQEKELVKQKAKELLLDLLSIYTPSKSEANATKFFEKISKDLNLKLEILPDSNSFILGE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCEEEEC
GDILLASHVDTVYGYIEPKIENELIYGRGAVDAKGPLISMIIATWLLNEKGIKVRVSGLA
CCEEEEECHHHHHHEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCC
DEESTSIGAKELIAKNYNFKYIIVGEPSNATDIVVEYRGSIQLDIMCEGTPEHSSSAKNN
CCCCCCCCHHHHHHCCCCEEEEEEECCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCC
LIVDISKKIIEVYKQPENYDKPSIVPTIIRAGESYNVTPAKLYLHLDIRYAINNKREDLI
EEEEHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEEEEEEEEECCCHHHHH
KEITDKFPECNLKIVDETPPVKVSINNPVVKSLARALLKQNIKPRLVKKAGTSDMNILQR
HHHHHCCCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHH
ITTNIATYGPGNSMLEHTTQEKISLDEIYIGVKTYMLAIEELWQKI
HHHHHEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLQEKELVKQKAKELLLDLLSIYTPSKSEANATKFFEKISKDLNLKLEILPDSNSFILGE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCEEEEC
GDILLASHVDTVYGYIEPKIENELIYGRGAVDAKGPLISMIIATWLLNEKGIKVRVSGLA
CCEEEEECHHHHHHEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCC
DEESTSIGAKELIAKNYNFKYIIVGEPSNATDIVVEYRGSIQLDIMCEGTPEHSSSAKNN
CCCCCCCCHHHHHHCCCCEEEEEEECCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCC
LIVDISKKIIEVYKQPENYDKPSIVPTIIRAGESYNVTPAKLYLHLDIRYAINNKREDLI
EEEEHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEEEEEEEEECCCHHHHH
KEITDKFPECNLKIVDETPPVKVSINNPVVKSLARALLKQNIKPRLVKKAGTSDMNILQR
HHHHHCCCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHH
ITTNIATYGPGNSMLEHTTQEKISLDEIYIGVKTYMLAIEELWQKI
HHHHHEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA