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The map label for this gene is argD [H]

Identifier: 15897111

GI number: 15897111

Start: 133415

End: 134593

Strand: Direct

Name: argD [H]

Synonym: SSO0160

Alternate gene names: 15897111

Gene position: 133415-134593 (Clockwise)

Preceding gene: 15897110

Following gene: 15897112

Centisome position: 4.46

GC content: 34.86

Gene sequence:

>1179_bases
ATGGGTGAAAAAATGATAAAGTTATTAAAATTCTATCAAGACAGAGGAATTAAAATTATTAAAGGAGAAGGGCAATACGT
CTGGGATGAAAAGAACAATAAATATTTGGATATGCACGCGGGGCATGGAGTAGCCTTTCTTGGTCATAGAAATAAAGTTA
TTATTGATCATTTGAAAAAGCAAATGGAGGAAATCTCTACTCTTTCCTTAGCTTTTGATACACCAATACGAGAAGAGATG
ATAAAAGAACTAGATGAGTTAAAACCAGAGGACTTAGATAATTTATTCCTTTTGAATAGTGGATCTGAAGCAGTAGAGTT
GGCATTAAAAATTGCTAGAAAAATTACCAAAAGAAGAAAAATTGTTGCATTTAAAAACTCCTTCCATGGAAGAAGTATGG
GTGCCCTATCAGTAACTTGGAATAAGAAATATAGAGAACCTTTTGAACCATTAATCGGCCCAGTAGAATTCTTAGAATAT
AATAATGTAGATTCTCTAAAGAGTATTACGGAAGATACGGCTGCAGTAATAGTAGAACCAGTACAAGGTGAAGGGGGTGT
AATACCAGCTAAGAAAGAGTTTGTAAAGAGTTTAAGAGAAGTTACGGAAAAGGTTAACGCTCTGTTAATTATAGATGAAG
TCCAAACGGGATTCGGTAGAACTGGTAAAATATGGGCATACCAACATTTTGATATAAAACCAGATATACTAACAGCAGGC
AAAGCTATTGGTGGAGGTTTCCCAGTAAGTGCAGTATTTTTACCAAATTGGATAAGTGAGAAAATAGAGGAAGGTGATCA
TGGTTCTACCTATGGGGGAAATCCATTAGCAGCCGCTGCAGTTACTGCAGCATGTAAAGTTGCAAAGTCCGAGAAGATTG
CAGAACAAGCTCAAAAGAAAGGAGAACTATTTATGAGAATTCTAAAAGAGAAATTAGAAGATTTCAAAATAGTTAGAGAA
ATAAGGGGACTTGGATTAATGATAGGAATAGATTTAAAGGTCAATCCTTCGATTGCTATAAAAGTCTTACAAGATGAGAA
GGTATTATCATTAAAAGCAGGACTTACAACAATAAGATTCCTACCTCCGTATTTAATAACTCAATCAGATATGGAGTGGG
CTTCAGATGCTACAAGAAAAGGAATTAGTGAAACAGAAAGCAAAAGAGTTGCTTCTTGA

Upstream 100 bases:

>100_bases
GATACCTCGTAGATGAAGTTAATGGAGTACCAGAATACAAAAATACTGTAAGAGTAAACAATTTTAATGTATCAAAATTC
CTTTTAGAAAAGGCAGCGGA

Downstream 100 bases:

>100_bases
TCTTTTATCAATATACACACCGTCAAAGAGTGAAGCAAACGCTACAAAATTCTTTGAGAAAATTTCCAAGGACTTAAACC
TTAAACTTGAGATTCTACCA

Product: acetylornithine aminotransferase ArgD

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MGEKMIKLLKFYQDRGIKIIKGEGQYVWDEKNNKYLDMHAGHGVAFLGHRNKVIIDHLKKQMEEISTLSLAFDTPIREEM
IKELDELKPEDLDNLFLLNSGSEAVELALKIARKITKRRKIVAFKNSFHGRSMGALSVTWNKKYREPFEPLIGPVEFLEY
NNVDSLKSITEDTAAVIVEPVQGEGGVIPAKKEFVKSLREVTEKVNALLIIDEVQTGFGRTGKIWAYQHFDIKPDILTAG
KAIGGGFPVSAVFLPNWISEKIEEGDHGSTYGGNPLAAAAVTAACKVAKSEKIAEQAQKKGELFMRILKEKLEDFKIVRE
IRGLGLMIGIDLKVNPSIAIKVLQDEKVLSLKAGLTTIRFLPPYLITQSDMEWASDATRKGISETESKRVAS

Sequences:

>Translated_392_residues
MGEKMIKLLKFYQDRGIKIIKGEGQYVWDEKNNKYLDMHAGHGVAFLGHRNKVIIDHLKKQMEEISTLSLAFDTPIREEM
IKELDELKPEDLDNLFLLNSGSEAVELALKIARKITKRRKIVAFKNSFHGRSMGALSVTWNKKYREPFEPLIGPVEFLEY
NNVDSLKSITEDTAAVIVEPVQGEGGVIPAKKEFVKSLREVTEKVNALLIIDEVQTGFGRTGKIWAYQHFDIKPDILTAG
KAIGGGFPVSAVFLPNWISEKIEEGDHGSTYGGNPLAAAAVTAACKVAKSEKIAEQAQKKGELFMRILKEKLEDFKIVRE
IRGLGLMIGIDLKVNPSIAIKVLQDEKVLSLKAGLTTIRFLPPYLITQSDMEWASDATRKGISETESKRVAS
>Mature_391_residues
GEKMIKLLKFYQDRGIKIIKGEGQYVWDEKNNKYLDMHAGHGVAFLGHRNKVIIDHLKKQMEEISTLSLAFDTPIREEMI
KELDELKPEDLDNLFLLNSGSEAVELALKIARKITKRRKIVAFKNSFHGRSMGALSVTWNKKYREPFEPLIGPVEFLEYN
NVDSLKSITEDTAAVIVEPVQGEGGVIPAKKEFVKSLREVTEKVNALLIIDEVQTGFGRTGKIWAYQHFDIKPDILTAGK
AIGGGFPVSAVFLPNWISEKIEEGDHGSTYGGNPLAAAAVTAACKVAKSEKIAEQAQKKGELFMRILKEKLEDFKIVREI
RGLGLMIGIDLKVNPSIAIKVLQDEKVLSLKAGLTTIRFLPPYLITQSDMEWASDATRKGISETESKRVAS

Specific function: Involved in both the arginine and lysine biosynthetic pathways [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=375, Percent_Identity=33.3333333333333, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI13994255, Length=442, Percent_Identity=28.5067873303167, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI37574042, Length=413, Percent_Identity=29.5399515738499, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI226442705, Length=415, Percent_Identity=29.1566265060241, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI24119277, Length=350, Percent_Identity=29.7142857142857, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI284507298, Length=289, Percent_Identity=36.3321799307958, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI226442709, Length=377, Percent_Identity=28.9124668435013, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI188536080, Length=411, Percent_Identity=23.6009732360097, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI38679950, Length=411, Percent_Identity=23.6009732360097, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI38679946, Length=411, Percent_Identity=23.6009732360097, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI1789759, Length=378, Percent_Identity=36.2433862433862, Blast_Score=254, Evalue=7e-69,
Organism=Escherichia coli, GI1788044, Length=368, Percent_Identity=36.1413043478261, Blast_Score=248, Evalue=7e-67,
Organism=Escherichia coli, GI145693181, Length=373, Percent_Identity=33.2439678284182, Blast_Score=218, Evalue=6e-58,
Organism=Escherichia coli, GI1787560, Length=407, Percent_Identity=30.7125307125307, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1789016, Length=336, Percent_Identity=31.8452380952381, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1786991, Length=404, Percent_Identity=29.4554455445545, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786349, Length=335, Percent_Identity=30.1492537313433, Blast_Score=129, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI25144271, Length=386, Percent_Identity=33.6787564766839, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI32564660, Length=431, Percent_Identity=30.3944315545244, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI71992977, Length=359, Percent_Identity=33.1476323119777, Blast_Score=171, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI25144274, Length=378, Percent_Identity=31.4814814814815, Blast_Score=171, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI17541228, Length=430, Percent_Identity=25.1162790697674, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71981843, Length=172, Percent_Identity=26.1627906976744, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324432, Length=399, Percent_Identity=36.5914786967419, Blast_Score=247, Evalue=3e-66,
Organism=Saccharomyces cerevisiae, GI6323470, Length=403, Percent_Identity=31.7617866004963, Blast_Score=200, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6321456, Length=377, Percent_Identity=27.0557029177719, Blast_Score=109, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6324386, Length=294, Percent_Identity=28.9115646258503, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357415, Length=384, Percent_Identity=35.15625, Blast_Score=214, Evalue=6e-56,
Organism=Drosophila melanogaster, GI28574759, Length=421, Percent_Identity=29.9287410926366, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI161085790, Length=410, Percent_Identity=29.2682926829268, Blast_Score=175, Evalue=6e-44,
Organism=Drosophila melanogaster, GI21356575, Length=355, Percent_Identity=29.2957746478873, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI281366494, Length=297, Percent_Identity=29.2929292929293, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24667139, Length=297, Percent_Identity=29.2929292929293, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24667143, Length=297, Percent_Identity=29.2929292929293, Blast_Score=105, Evalue=6e-23,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43769; Mature: 43638

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEKMIKLLKFYQDRGIKIIKGEGQYVWDEKNNKYLDMHAGHGVAFLGHRNKVIIDHLKK
CCHHHHHHHHHHHHCCEEEEECCCCEEEECCCCEEEEEECCCCEEEECCCCCHHHHHHHH
QMEEISTLSLAFDTPIREEMIKELDELKPEDLDNLFLLNSGSEAVELALKIARKITKRRK
HHHHHHHHHEEECCCHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHH
IVAFKNSFHGRSMGALSVTWNKKYREPFEPLIGPVEFLEYNNVDSLKSITEDTAAVIVEP
EEEEECCCCCCCCCEEEEEECCHHCCCHHHHHCHHHHHHCCCHHHHHHHHCCCEEEEEEE
VQGEGGVIPAKKEFVKSLREVTEKVNALLIIDEVQTGFGRTGKIWAYQHFDIKPDILTAG
ECCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEHHCCCCCCCEEEEEEECCCCCCHHHCC
KAIGGGFPVSAVFLPNWISEKIEEGDHGSTYGGNPLAAAAVTAACKVAKSEKIAEQAQKK
CCCCCCCCCHHEECCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GELFMRILKEKLEDFKIVREIRGLGLMIGIDLKVNPSIAIKVLQDEKVLSLKAGLTTIRF
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCEEEEEECCCCEEEHHHCCCEEEE
LPPYLITQSDMEWASDATRKGISETESKRVAS
CCCHHEECCCHHHHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure 
GEKMIKLLKFYQDRGIKIIKGEGQYVWDEKNNKYLDMHAGHGVAFLGHRNKVIIDHLKK
CHHHHHHHHHHHHCCEEEEECCCCEEEECCCCEEEEEECCCCEEEECCCCCHHHHHHHH
QMEEISTLSLAFDTPIREEMIKELDELKPEDLDNLFLLNSGSEAVELALKIARKITKRRK
HHHHHHHHHEEECCCHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHH
IVAFKNSFHGRSMGALSVTWNKKYREPFEPLIGPVEFLEYNNVDSLKSITEDTAAVIVEP
EEEEECCCCCCCCCEEEEEECCHHCCCHHHHHCHHHHHHCCCHHHHHHHHCCCEEEEEEE
VQGEGGVIPAKKEFVKSLREVTEKVNALLIIDEVQTGFGRTGKIWAYQHFDIKPDILTAG
ECCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEHHCCCCCCCEEEEEEECCCCCCHHHCC
KAIGGGFPVSAVFLPNWISEKIEEGDHGSTYGGNPLAAAAVTAACKVAKSEKIAEQAQKK
CCCCCCCCCHHEECCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GELFMRILKEKLEDFKIVREIRGLGLMIGIDLKVNPSIAIKVLQDEKVLSLKAGLTTIRF
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCEEEEEECCCCEEEHHHCCCEEEE
LPPYLITQSDMEWASDATRKGISETESKRVAS
CCCHHEECCCHHHHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11427726; 12042311 [H]