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The map label for this gene is argC

Identifier: 15897106

GI number: 15897106

Start: 130070

End: 131128

Strand: Direct

Name: argC

Synonym: SSO0155

Alternate gene names: 15897106

Gene position: 130070-131128 (Clockwise)

Preceding gene: 15897104

Following gene: 15897107

Centisome position: 4.35

GC content: 38.34

Gene sequence:

>1059_bases
ATGAAAGATAAAGTTAGAGTTGCCGTAGTTGGAGGTTCAGGATATACGGGCGGAGAATTACTAAGAATATTAGTTACACA
TCCGAAGACAGAAATATCAGTCATAACTTCTAGAGAATATGCGGGAAAACCAGTATCATTGATACATCCGAATTTAAGAG
GACTAATATCTCTTAATTTTACAAATTTCTCAATAGATAAGATCTCAGACAAAGCTGACGCAATTTTTCTTGCTCTACCT
CATGGAGTATCGTTAAATTACGCGCCTAAATTACTAGATTTAGGATTGACAGTCGTGGATTTAAGTGCAGATTTTAGACT
CAAAAATCCAGAACTTTATAAAATATGGTACAATTATGAACATCCTTATCCAGATCTATTAGACAAGGCGGTATATGGGC
TACCAGAGTTACATTACGAGGAATTAAAAAATGCTAAACTTATAGCATCCCCAGGCTGTAATGCAACTGCAACTATACTA
GCGTTAGCCCCAATTGTGGCAACAAAAATAACTGACGAGAAAAAGTTCATCAGCGACGTAAAAGTAGGCAGTAGCGAAGG
AGGAGCAAAACCATCAGAAGGTAGCCATCATCCAGAGAGACAAAATGCAATTAGACCTTATGAAGCTGAAGGGCATAGAC
ACGCAGCAGAGGCTGAACAAGAACTGTCTAGAATAGCTAAAGCAAATATAAGCGTGAGTATTGTCCCTCATGCAGTGAGT
AGCATCAGAGGAGCCTTAGCGTCTGCACATACGTGGTTAACTAATGAACTAGAAGAGATTGAAATATGGAAAAAAATAGC
TGAGTTTTATAGGGGTAAGAGATTCATTAGAATAATTAGGGGAAACATACACCCATATCCTGATCCAAAATTCGTTATCG
GAAGCAACTTTGCTGATATAGGATTCGCTGTAGAAAAGAGAATTTCAAGACTAACAACGTTCTCCGCTATAGATAATTTA
ATGAAAGGCGCTGCTGGCCAAGCTGTCCAAGCTTTCAATATTTCTATGGGATTTAACGAAGATGACGGATTAAAACTAGT
ACCCTTGAGGCCTGCCTAA

Upstream 100 bases:

>100_bases
TTACTCTCAAGGAATTTTTTTAGTTCATCAGTGTTAACACTCATCACAAATATCTATATACATTAAACTATATATAACCT
AAACTGCAATAGTTAGTTTA

Downstream 100 bases:

>100_bases
AATGATAGTAGTTAAAATAGGTGGAAGAGTAGTTAAGAATTCATTAGATAAGATAATTTTAGATATATTAAATATAAATG
ACAAGGTAATCTTGGTGCAT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde/N-acetyl-aminoadipate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MKDKVRVAVVGGSGYTGGELLRILVTHPKTEISVITSREYAGKPVSLIHPNLRGLISLNFTNFSIDKISDKADAIFLALP
HGVSLNYAPKLLDLGLTVVDLSADFRLKNPELYKIWYNYEHPYPDLLDKAVYGLPELHYEELKNAKLIASPGCNATATIL
ALAPIVATKITDEKKFISDVKVGSSEGGAKPSEGSHHPERQNAIRPYEAEGHRHAAEAEQELSRIAKANISVSIVPHAVS
SIRGALASAHTWLTNELEEIEIWKKIAEFYRGKRFIRIIRGNIHPYPDPKFVIGSNFADIGFAVEKRISRLTTFSAIDNL
MKGAAGQAVQAFNISMGFNEDDGLKLVPLRPA

Sequences:

>Translated_352_residues
MKDKVRVAVVGGSGYTGGELLRILVTHPKTEISVITSREYAGKPVSLIHPNLRGLISLNFTNFSIDKISDKADAIFLALP
HGVSLNYAPKLLDLGLTVVDLSADFRLKNPELYKIWYNYEHPYPDLLDKAVYGLPELHYEELKNAKLIASPGCNATATIL
ALAPIVATKITDEKKFISDVKVGSSEGGAKPSEGSHHPERQNAIRPYEAEGHRHAAEAEQELSRIAKANISVSIVPHAVS
SIRGALASAHTWLTNELEEIEIWKKIAEFYRGKRFIRIIRGNIHPYPDPKFVIGSNFADIGFAVEKRISRLTTFSAIDNL
MKGAAGQAVQAFNISMGFNEDDGLKLVPLRPA
>Mature_352_residues
MKDKVRVAVVGGSGYTGGELLRILVTHPKTEISVITSREYAGKPVSLIHPNLRGLISLNFTNFSIDKISDKADAIFLALP
HGVSLNYAPKLLDLGLTVVDLSADFRLKNPELYKIWYNYEHPYPDLLDKAVYGLPELHYEELKNAKLIASPGCNATATIL
ALAPIVATKITDEKKFISDVKVGSSEGGAKPSEGSHHPERQNAIRPYEAEGHRHAAEAEQELSRIAKANISVSIVPHAVS
SIRGALASAHTWLTNELEEIEIWKKIAEFYRGKRFIRIIRGNIHPYPDPKFVIGSNFADIGFAVEKRISRLTTFSAIDNL
MKGAAGQAVQAFNISMGFNEDDGLKLVPLRPA

Specific function: Involved in both the arginine and lysine biosynthetic pathways

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=341, Percent_Identity=34.8973607038123, Blast_Score=179, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6320913, Length=344, Percent_Identity=28.4883720930233, Blast_Score=96, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_SULSO (Q980X1)

Other databases:

- EMBL:   AE006641
- EMBL:   BK000545
- PIR:   F90155
- RefSeq:   NP_341711.1
- ProteinModelPortal:   Q980X1
- SMR:   Q980X1
- GeneID:   1453328
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO0155
- NMPDR:   fig|273057.1.peg.134
- HOGENOM:   HBG294213
- OMA:   GCMATAS
- PhylomeDB:   Q980X1
- ProtClustDB:   PRK00436
- BioCyc:   SSOL273057:SSO0155-MONOMER
- BRENDA:   1.2.1.38
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 38686; Mature: 38686

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 153-153

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDKVRVAVVGGSGYTGGELLRILVTHPKTEISVITSREYAGKPVSLIHPNLRGLISLNF
CCCCEEEEEECCCCCCHHHEEEEEEECCCCEEEEEECCCCCCCCCEEECCCCCEEEEEEE
TNFSIDKISDKADAIFLALPHGVSLNYAPKLLDLGLTVVDLSADFRLKNPELYKIWYNYE
CCEEHHHCCCCCCEEEEEECCCCCCCCCCHHHHCCCEEEEECCCEEECCCCEEEEEECCC
HPYPDLLDKAVYGLPELHYEELKNAKLIASPGCNATATILALAPIVATKITDEKKFISDV
CCCHHHHHHHHHCCCCHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
KVGSSEGGAKPSEGSHHPERQNAIRPYEAEGHRHAAEAEQELSRIAKANISVSIVPHAVS
CCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHH
SIRGALASAHTWLTNELEEIEIWKKIAEFYRGKRFIRIIRGNIHPYPDPKFVIGSNFADI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEECCCCHHH
GFAVEKRISRLTTFSAIDNLMKGAAGQAVQAFNISMGFNEDDGLKLVPLRPA
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEEEECCCC
>Mature Secondary Structure
MKDKVRVAVVGGSGYTGGELLRILVTHPKTEISVITSREYAGKPVSLIHPNLRGLISLNF
CCCCEEEEEECCCCCCHHHEEEEEEECCCCEEEEEECCCCCCCCCEEECCCCCEEEEEEE
TNFSIDKISDKADAIFLALPHGVSLNYAPKLLDLGLTVVDLSADFRLKNPELYKIWYNYE
CCEEHHHCCCCCCEEEEEECCCCCCCCCCHHHHCCCEEEEECCCEEECCCCEEEEEECCC
HPYPDLLDKAVYGLPELHYEELKNAKLIASPGCNATATILALAPIVATKITDEKKFISDV
CCCHHHHHHHHHCCCCHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
KVGSSEGGAKPSEGSHHPERQNAIRPYEAEGHRHAAEAEQELSRIAKANISVSIVPHAVS
CCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHH
SIRGALASAHTWLTNELEEIEIWKKIAEFYRGKRFIRIIRGNIHPYPDPKFVIGSNFADI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEECCCCHHH
GFAVEKRISRLTTFSAIDNLMKGAAGQAVQAFNISMGFNEDDGLKLVPLRPA
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726; 12042311