Click here to switch to the map view.

The map label for this gene is acuC [H]

Identifier: 15896999

GI number: 15896999

Start: 25702

End: 26757

Strand: Reverse

Name: acuC [H]

Synonym: SSO0028

Alternate gene names: 15896999

Gene position: 26757-25702 (Counterclockwise)

Preceding gene: 15897002

Following gene: 15896996

Centisome position: 0.89

GC content: 37.88

Gene sequence:

>1056_bases
TTGCACAAAACGGCTTTTATATGGACAGACGAATATTATAACTATTCGTTCCCAGACTATCATCCATTTAAATCCCTGAG
AGAAAGCATGACTAAAAGGCTCCTAGAAGAAAGAGGTGCATTTCATTTCATCACACTAGTTGAACCCAAGTCGATTCCAG
AAGAGGCTCTTCAGCTGGTACACTCCAAAGAATATATAGAATTTGTAAAATATAAAAGTAAGGAGGGTCAAGGCTATTTG
GATGACGGAGATACTCCAGCGTTTAAGGGTATATATGAGGCGGCATTAATCAGAGTAAGTGGTAGTGTAAAGGCATTAGA
GTTAATAAAAAGTGGAGAATTTAACCACACTATCAATATTGGTGGAGGTTTTCATCATGCAAAGAGGAATAGAGCAGCTG
GTTTTTGCGTTTTTAACGATGTGGCTCTAATATCTAAATTAGGGGAGAGTTTCTTTTCAAGAATAGCCATAGTTGATATA
GATGGTCATCACGCTGATGGTACACAAGAGCTATTAATTGATGATAATAATATTTTGAAAATTTCTTTACACATGTTTCA
TCCTAATTTCTTCCCGGGTACCGGGGATGTGAACGAGATCGGGCTAGGGAAAGGGGAAGGGTATACTATCAATATCCCTC
TTCCACCTGGTACTGGAGATGATGGTTATCTCTTAGCCTTCGACGAAATAGTAGTCCCCGCTATAGAAAGATATAAGCCA
GAACTAATTATTCTTGTAGCAGGTGGTGATTCTCATTTTAACGACCCTTTAGTTGAGTTAAAATTATCTACCCATGGCTA
TTTAGATGTGGTAACCAAGATCCATCGCCTAGTTCACGAATATTCTAATGGTAGGCTCATAATGTTAGGTGGGGGTGGAT
ATAATTACGATGCGACTGCCAGAATTTGGACAATTTCAATAGCCGAGATAGCTGGAATATACGACTTAGAATATGAAACT
CTTCATGACTCCTTCTCAACTAAATCGTCGCAGTTTGTTATGGAGAAAATAAGAAACACTATAAGTCTAATAAAGAAGAT
ACATTCACTTAACTAA

Upstream 100 bases:

>100_bases
TCCATACTATGCGCAACATAACTCGGCTTTGTGATGAGTGTGTTATCTATCATACTAGATAAGTATTTTAAATTGAAAAA
TAAAAAAGTAGTGATATACT

Downstream 100 bases:

>100_bases
TATTATTGAAGATGCCTTTCTAACTTTTTCTAACGCCTCTTCTACACTATTTCCAGTTGCCAATACTACACCCATTCTTC
TCTTCTCGTATGTAACAGGT

Product: acetylpolyamine aminohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MHKTAFIWTDEYYNYSFPDYHPFKSLRESMTKRLLEERGAFHFITLVEPKSIPEEALQLVHSKEYIEFVKYKSKEGQGYL
DDGDTPAFKGIYEAALIRVSGSVKALELIKSGEFNHTINIGGGFHHAKRNRAAGFCVFNDVALISKLGESFFSRIAIVDI
DGHHADGTQELLIDDNNILKISLHMFHPNFFPGTGDVNEIGLGKGEGYTINIPLPPGTGDDGYLLAFDEIVVPAIERYKP
ELIILVAGGDSHFNDPLVELKLSTHGYLDVVTKIHRLVHEYSNGRLIMLGGGGYNYDATARIWTISIAEIAGIYDLEYET
LHDSFSTKSSQFVMEKIRNTISLIKKIHSLN

Sequences:

>Translated_351_residues
MHKTAFIWTDEYYNYSFPDYHPFKSLRESMTKRLLEERGAFHFITLVEPKSIPEEALQLVHSKEYIEFVKYKSKEGQGYL
DDGDTPAFKGIYEAALIRVSGSVKALELIKSGEFNHTINIGGGFHHAKRNRAAGFCVFNDVALISKLGESFFSRIAIVDI
DGHHADGTQELLIDDNNILKISLHMFHPNFFPGTGDVNEIGLGKGEGYTINIPLPPGTGDDGYLLAFDEIVVPAIERYKP
ELIILVAGGDSHFNDPLVELKLSTHGYLDVVTKIHRLVHEYSNGRLIMLGGGGYNYDATARIWTISIAEIAGIYDLEYET
LHDSFSTKSSQFVMEKIRNTISLIKKIHSLN
>Mature_351_residues
MHKTAFIWTDEYYNYSFPDYHPFKSLRESMTKRLLEERGAFHFITLVEPKSIPEEALQLVHSKEYIEFVKYKSKEGQGYL
DDGDTPAFKGIYEAALIRVSGSVKALELIKSGEFNHTINIGGGFHHAKRNRAAGFCVFNDVALISKLGESFFSRIAIVDI
DGHHADGTQELLIDDNNILKISLHMFHPNFFPGTGDVNEIGLGKGEGYTINIPLPPGTGDDGYLLAFDEIVVPAIERYKP
ELIILVAGGDSHFNDPLVELKLSTHGYLDVVTKIHRLVHEYSNGRLIMLGGGGYNYDATARIWTISIAEIAGIYDLEYET
LHDSFSTKSSQFVMEKIRNTISLIKKIHSLN

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI8923769, Length=338, Percent_Identity=31.6568047337278, Blast_Score=175, Evalue=5e-44,
Organism=Homo sapiens, GI13128860, Length=315, Percent_Identity=31.1111111111111, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI13128862, Length=367, Percent_Identity=29.9727520435967, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI293336691, Length=314, Percent_Identity=32.1656050955414, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI262073092, Length=222, Percent_Identity=35.1351351351351, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI262073088, Length=256, Percent_Identity=31.25, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI13128864, Length=309, Percent_Identity=30.42071197411, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI30795204, Length=317, Percent_Identity=30.9148264984227, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI30795202, Length=317, Percent_Identity=30.9148264984227, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI20070354, Length=325, Percent_Identity=26.7692307692308, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI17158039, Length=243, Percent_Identity=34.156378600823, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI148539870, Length=139, Percent_Identity=42.4460431654676, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI169234807, Length=139, Percent_Identity=42.4460431654676, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI153085395, Length=319, Percent_Identity=30.0940438871473, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI62750349, Length=211, Percent_Identity=33.6492890995261, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI62750347, Length=211, Percent_Identity=33.6492890995261, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI209862883, Length=299, Percent_Identity=27.0903010033445, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI226529806, Length=246, Percent_Identity=28.4552845528455, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI217272877, Length=315, Percent_Identity=27.3015873015873, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17508561, Length=314, Percent_Identity=29.9363057324841, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17561978, Length=311, Percent_Identity=32.1543408360129, Blast_Score=164, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI17534739, Length=319, Percent_Identity=28.8401253918495, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17540334, Length=348, Percent_Identity=27.0114942528736, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI193206283, Length=348, Percent_Identity=27.0114942528736, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17540332, Length=348, Percent_Identity=27.0114942528736, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI193209491, Length=323, Percent_Identity=27.5541795665635, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17537347, Length=350, Percent_Identity=24, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI25154020, Length=269, Percent_Identity=26.7657992565056, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI25154022, Length=271, Percent_Identity=25.4612546125461, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI193207430, Length=299, Percent_Identity=26.4214046822742, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321244, Length=348, Percent_Identity=31.3218390804598, Blast_Score=172, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6323999, Length=334, Percent_Identity=28.4431137724551, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6325325, Length=233, Percent_Identity=33.9055793991416, Blast_Score=135, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6324307, Length=323, Percent_Identity=29.7213622291022, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24657891, Length=363, Percent_Identity=32.2314049586777, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24644244, Length=314, Percent_Identity=29.2993630573248, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24642146, Length=305, Percent_Identity=27.2131147540984, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24642144, Length=305, Percent_Identity=27.2131147540984, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24642142, Length=305, Percent_Identity=27.2131147540984, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281360899, Length=309, Percent_Identity=27.831715210356, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24641720, Length=186, Percent_Identity=33.8709677419355, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI281360801, Length=186, Percent_Identity=33.8709677419355, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI281360799, Length=186, Percent_Identity=33.8709677419355, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24649807, Length=306, Percent_Identity=25.8169934640523, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003085
- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 39389; Mature: 39389

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKTAFIWTDEYYNYSFPDYHPFKSLRESMTKRLLEERGAFHFITLVEPKSIPEEALQLV
CCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHH
HSKEYIEFVKYKSKEGQGYLDDGDTPAFKGIYEAALIRVSGSVKALELIKSGEFNHTINI
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHEEEEEECCCHHHHHHHHCCCCCEEEEC
GGGFHHAKRNRAAGFCVFNDVALISKLGESFFSRIAIVDIDGHHADGTQELLIDDNNILK
CCCCCHHHCCCCCEEEEEHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCEEEEECCCEEE
ISLHMFHPNFFPGTGDVNEIGLGKGEGYTINIPLPPGTGDDGYLLAFDEIVVPAIERYKP
EEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEHHHHHHHHHHCCC
ELIILVAGGDSHFNDPLVELKLSTHGYLDVVTKIHRLVHEYSNGRLIMLGGGGYNYDATA
CEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCE
RIWTISIAEIAGIYDLEYETLHDSFSTKSSQFVMEKIRNTISLIKKIHSLN
EEEEEEHHHHCCEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHKTAFIWTDEYYNYSFPDYHPFKSLRESMTKRLLEERGAFHFITLVEPKSIPEEALQLV
CCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHH
HSKEYIEFVKYKSKEGQGYLDDGDTPAFKGIYEAALIRVSGSVKALELIKSGEFNHTINI
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHEEEEEECCCHHHHHHHHCCCCCEEEEC
GGGFHHAKRNRAAGFCVFNDVALISKLGESFFSRIAIVDIDGHHADGTQELLIDDNNILK
CCCCCHHHCCCCCEEEEEHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCEEEEECCCEEE
ISLHMFHPNFFPGTGDVNEIGLGKGEGYTINIPLPPGTGDDGYLLAFDEIVVPAIERYKP
EEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEHHHHHHHHHHCCC
ELIILVAGGDSHFNDPLVELKLSTHGYLDVVTKIHRLVHEYSNGRLIMLGGGGYNYDATA
CEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCE
RIWTISIAEIAGIYDLEYETLHDSFSTKSSQFVMEKIRNTISLIKKIHSLN
EEEEEEHHHHCCEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]