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The map label for this gene is queC

Identifier: 15896988

GI number: 15896988

Start: 13920

End: 15314

Strand: Reverse

Name: queC

Synonym: SSO0016

Alternate gene names: 15896988

Gene position: 15314-13920 (Counterclockwise)

Preceding gene: 15896991

Following gene: 15896987

Centisome position: 0.51

GC content: 36.92

Gene sequence:

>1395_bases
GTGTGCAGTGTATCTGGAGTCCTCATATTAAACCCTAAAAATTTTGAGAAAGTTGAGCTGAAATTAGCTAGTATCCTCAA
AAAGGCAGAAGATAGGGGTAGGGACAGTTTTGGTATTGTTGTAATTCAAAAGGATGGTACAGTAAAAGTAAGAAAATCCA
TAGGAAAGCCCTCAGAAAAAGAGGAATTACTATACGGCATTTTAGATGAAGACTCTAGGGTTGTCATAGCTAATAATAGG
GCAGAACCCACTACTGAATACGTTAGACAGAAAACTGAGGACGACATTCAACCTTTTATTGGAGACAGATATATTGTAAC
TCATAATGGAATAATCGCAAATGATTTAGAATTAGAGAAAAAATATGAATTAAAAAGAAAAACTAAGATAGATAGTGCAA
TTCTTCCACTACTTTTGGACAAGACGTGGGACGGTAATCTTGAAGCACTAAAGGGAATATTAGAGCAAATCAAAGGAAGT
TTTGCTTTGGTTATAGGAGATAAGAAAAACCCTGATAGAATATTTCTAGCTCAGAACTTTAAGCCATTATACATGGCTTA
TGACCACTCGTTGGAGTCCCTATTCTTTACATCTCTTGACGAATATTTTGATGCAAAACCATTCGACCCAGTAAATATAA
CTAAATTGGAACCATATTCGGTAGTAATGGTCACTTCGAATAAACTAATAACTACGTTGCCTATCATGGAAAAAAGAAAG
AAGTATAGGGTACTTGTTGTGGCAAGTGGTGGGTTAGATTCCACTGTAGCAGCAACTAAACTTCTAAGAGAAGGTCATGA
AGTTACTCTAATACACTTTAATTACCACCATAAGGCTGAGGAAAAGGAAAGAGAGGCCGTGAGGAAAATTGCCGAATATT
TGCAAATACCACTGCTTGAAATAAATACAGATTTATTCAAAATAATAGGTCATGCCACGTTAATAAAGGGAGGAGGAGAG
ATAGTTAAGGATAGGAAAGGAGAAGAAGGAGCAGAGTTTGCACATGAATGGGTTCCTGCAAGAAATCTAATTTTCTTCTC
TGTTTCATTAGCAATTGCCGAAGCCTATGGATATGATGCCATAGCATCTGGAATAAATTTAGAGGAAGCTGGAGCTTATC
CAGATAACGAGATGGAATTCATAAGGATGTTAAATAAGTTAAGCCCATATGCAACTGGTCCAAACAAGAGAATTGAGATA
TTAATGCCAGTTGGTAATTTAGTAAAGCACGAAATAGTAAAGCTGGGATACGAAATTGGTGCCCCACTACATTTGACCTG
GAGCTGTTATGAAGGTGGGCAAAAACATTGTGGGAAATGTGGGCCTTGTTATATGAGGAAGATGGCGTTTAGGATCAATG
GACTTAAAGATCCAGTTGAATATGATGAAGAGTGA

Upstream 100 bases:

>100_bases
GGATTCTCCATGGTCGATGGCGAAAATTTAGAAGAAGACCTAATTATGATAAAATTAGAGTTTAGACAGATTTTTAGGTA
AGTTATAAAGGTATAAACAA

Downstream 100 bases:

>100_bases
TAGAATACTTTAATAACCATTTAGTTAGTAGTATATTTTATGTTGACGCCAATAGAATTTTTTGTTACAGTTGTGCTAAT
AAGTGCTCTTTCAGGTATAC

Product: transcription regulator (exsB) related protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; Archaeosine biosynthesis protein queC; PreQ(0) synthase

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MCSVSGVLILNPKNFEKVELKLASILKKAEDRGRDSFGIVVIQKDGTVKVRKSIGKPSEKEELLYGILDEDSRVVIANNR
AEPTTEYVRQKTEDDIQPFIGDRYIVTHNGIIANDLELEKKYELKRKTKIDSAILPLLLDKTWDGNLEALKGILEQIKGS
FALVIGDKKNPDRIFLAQNFKPLYMAYDHSLESLFFTSLDEYFDAKPFDPVNITKLEPYSVVMVTSNKLITTLPIMEKRK
KYRVLVVASGGLDSTVAATKLLREGHEVTLIHFNYHHKAEEKEREAVRKIAEYLQIPLLEINTDLFKIIGHATLIKGGGE
IVKDRKGEEGAEFAHEWVPARNLIFFSVSLAIAEAYGYDAIASGINLEEAGAYPDNEMEFIRMLNKLSPYATGPNKRIEI
LMPVGNLVKHEIVKLGYEIGAPLHLTWSCYEGGQKHCGKCGPCYMRKMAFRINGLKDPVEYDEE

Sequences:

>Translated_464_residues
MCSVSGVLILNPKNFEKVELKLASILKKAEDRGRDSFGIVVIQKDGTVKVRKSIGKPSEKEELLYGILDEDSRVVIANNR
AEPTTEYVRQKTEDDIQPFIGDRYIVTHNGIIANDLELEKKYELKRKTKIDSAILPLLLDKTWDGNLEALKGILEQIKGS
FALVIGDKKNPDRIFLAQNFKPLYMAYDHSLESLFFTSLDEYFDAKPFDPVNITKLEPYSVVMVTSNKLITTLPIMEKRK
KYRVLVVASGGLDSTVAATKLLREGHEVTLIHFNYHHKAEEKEREAVRKIAEYLQIPLLEINTDLFKIIGHATLIKGGGE
IVKDRKGEEGAEFAHEWVPARNLIFFSVSLAIAEAYGYDAIASGINLEEAGAYPDNEMEFIRMLNKLSPYATGPNKRIEI
LMPVGNLVKHEIVKLGYEIGAPLHLTWSCYEGGQKHCGKCGPCYMRKMAFRINGLKDPVEYDEE
>Mature_464_residues
MCSVSGVLILNPKNFEKVELKLASILKKAEDRGRDSFGIVVIQKDGTVKVRKSIGKPSEKEELLYGILDEDSRVVIANNR
AEPTTEYVRQKTEDDIQPFIGDRYIVTHNGIIANDLELEKKYELKRKTKIDSAILPLLLDKTWDGNLEALKGILEQIKGS
FALVIGDKKNPDRIFLAQNFKPLYMAYDHSLESLFFTSLDEYFDAKPFDPVNITKLEPYSVVMVTSNKLITTLPIMEKRK
KYRVLVVASGGLDSTVAATKLLREGHEVTLIHFNYHHKAEEKEREAVRKIAEYLQIPLLEINTDLFKIIGHATLIKGGGE
IVKDRKGEEGAEFAHEWVPARNLIFFSVSLAIAEAYGYDAIASGINLEEAGAYPDNEMEFIRMLNKLSPYATGPNKRIEI
LMPVGNLVKHEIVKLGYEIGAPLHLTWSCYEGGQKHCGKCGPCYMRKMAFRINGLKDPVEYDEE

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-2 domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_SULSO (Q981C9)

Other databases:

- EMBL:   AE006641
- PIR:   H90140
- RefSeq:   NP_341593.1
- ProteinModelPortal:   Q981C9
- SMR:   Q981C9
- GeneID:   1455274
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO0016
- NMPDR:   fig|273057.1.peg.16
- HOGENOM:   HBG391796
- OMA:   TLLHFNY
- PhylomeDB:   Q981C9
- ProtClustDB:   CLSK883593
- BioCyc:   SSOL273057:SSO0016-MONOMER
- HAMAP:   MF_01633_A
- InterPro:   IPR017932
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 52383; Mature: 52383

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS51278 GATASE_TYPE_2

Important sites: ACT_SITE 2-2

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCSVSGVLILNPKNFEKVELKLASILKKAEDRGRDSFGIVVIQKDGTVKVRKSIGKPSEK
CCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEHHHCCCCCCH
EELLYGILDEDSRVVIANNRAEPTTEYVRQKTEDDIQPFIGDRYIVTHNGIIANDLELEK
HHHEEEEECCCCEEEEECCCCCCHHHHHHHCCCCCCCHHHCCEEEEEECCEEECCCCHHH
KYELKRKTKIDSAILPLLLDKTWDGNLEALKGILEQIKGSFALVIGDKKNPDRIFLAQNF
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCC
KPLYMAYDHSLESLFFTSLDEYFDAKPFDPVNITKLEPYSVVMVTSNKLITTLPIMEKRK
CEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEEEEEEECCCEEEECCHHHCCC
KYRVLVVASGGLDSTVAATKLLREGHEVTLIHFNYHHKAEEKEREAVRKIAEYLQIPLLE
CEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEE
INTDLFKIIGHATLIKGGGEIVKDRKGEEGAEFAHEWVPARNLIFFSVSLAIAEAYGYDA
ECHHHHHHHCCCEEEECCCHHHHCCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHCCCHH
IASGINLEEAGAYPDNEMEFIRMLNKLSPYATGPNKRIEILMPVGNLVKHEIVKLGYEIG
HHCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCC
APLHLTWSCYEGGQKHCGKCGPCYMRKMAFRINGLKDPVEYDEE
CCEEEEEEHHCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MCSVSGVLILNPKNFEKVELKLASILKKAEDRGRDSFGIVVIQKDGTVKVRKSIGKPSEK
CCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEHHHCCCCCCH
EELLYGILDEDSRVVIANNRAEPTTEYVRQKTEDDIQPFIGDRYIVTHNGIIANDLELEK
HHHEEEEECCCCEEEEECCCCCCHHHHHHHCCCCCCCHHHCCEEEEEECCEEECCCCHHH
KYELKRKTKIDSAILPLLLDKTWDGNLEALKGILEQIKGSFALVIGDKKNPDRIFLAQNF
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCC
KPLYMAYDHSLESLFFTSLDEYFDAKPFDPVNITKLEPYSVVMVTSNKLITTLPIMEKRK
CEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEEEEEEECCCEEEECCHHHCCC
KYRVLVVASGGLDSTVAATKLLREGHEVTLIHFNYHHKAEEKEREAVRKIAEYLQIPLLE
CEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEE
INTDLFKIIGHATLIKGGGEIVKDRKGEEGAEFAHEWVPARNLIFFSVSLAIAEAYGYDA
ECHHHHHHHCCCEEEECCCHHHHCCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHCCCHH
IASGINLEEAGAYPDNEMEFIRMLNKLSPYATGPNKRIEILMPVGNLVKHEIVKLGYEIG
HHCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCC
APLHLTWSCYEGGQKHCGKCGPCYMRKMAFRINGLKDPVEYDEE
CCEEEEEEHHCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11427726