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The map label for this gene is yflS [H]

Identifier: 15928280

GI number: 15928280

Start: 2796512

End: 2797930

Strand: Direct

Name: yflS [H]

Synonym: SA2486

Alternate gene names: 15928280

Gene position: 2796512-2797930 (Clockwise)

Preceding gene: 15928279

Following gene: 15928282

Centisome position: 99.35

GC content: 38.27

Gene sequence:

>1419_bases
ATGGAAAACACGGTTAAATATCGTAAGTTTATACTCCCTATCGTTGTAGGTCTCCTTATTTGGGCACTTACACCTTTTAA
ACCGGATGCTGTGGATCCAACAGCATGGTATATGTTCGCAATATTCGTCGCGACAATCATTGCTTGTATTACACAACCGA
TGCCAATTGGGGCCGTCTCTATAATTGGATTTACAATCATGGTACTCGTTGGCATTGTTGACATGAAAACGGCTGTCGCT
GGTTTTGGTAATAATAGCATTTGGTTAATTGCTATGGCATTTTTCATTTCGAGAGGATTTGTGAAAACAGGTCTTGGTAG
ACGGATCGCACTTCATTTCGTCAAATTATTTGGTAAAAAAACATTAGGCTTAGCATATTCTATCGTCGGTGTAGATTTAA
TTCTAGCGCCTGCTACACCGAGTAATACCGCGCGTGCTGGTGGAATCATGTTCCCAATTATCAAATCACTTTCTGAATCA
TTTGGTTCGAAACCGAAAGACGGATCAGCACGCAAAATGGGTGCATTTCTTGTTTTCACAGAATTCCAAGGTAATTTAAT
TACTGCGGCTATGTTTTTAACTGCAATGGCCGGTAACCCCCTTGCACAAAATTTAGCATCTAGCACATCTAATGTTCACA
TTACATGGATGAATTGGTTCCTAGCTGCTTTAGTTCCTGGACTTGTTTCCTTAATTGTTGTACCTTTTATTATTTATAAA
ATTTATCCACCAACTGTTAAAGAAACACCAAATGCTAAGAGTTGGGCTGAAAATGAATTAGCGACTATGGGTAAAATCGC
TTTAGCTGAAAAATTTATGATTGGTATTTTTGTCATTGCTCTAACATTATGGATTGTCGGAAGTTTCATTCATATTGATG
CAACTTTAACGGCCTTTATTGCGCTAGCATTGTTATTATTGACAGGTGTCTTAACATGGCAAGACATTTTAAACGAAACA
GGTGCTTGGAACACATTAGTATGGTTCTCAGTATTAGTGTTAATGGCCGACCAATTAAACAAGCTTGGATTTATTCCTTG
GTTAAGTAAATCCATTGCTACAAGTCTTGGTGGCTTAAGCTGGCCTATAGTACTGGTCATTTTAATATTGTTCTACTTCT
ATTCACATTACTTATTTGCAAGTTCTACAGCACATATCAGTGCGATGTATGCAGCATTACTAGGCGTTGCCATCGCAGCC
GGTGCACCACCATTATTCAGTGCATTAATGTTAGGTTTCTTCGGTAACCTATTAGCTTCAACAACACACTATAGTAGTGG
TCCAGCGCCGATTCTATTCTCTTCAGGTTACGTGACTCAAAAACGTTGGTGGACAATGAACTTGATCTTAGGTTTCGTCT
ACTTTATTATCTGGATTGGTTTAGGATCACTTTGGATGAAAGTAATTGGTATATTTTAA

Upstream 100 bases:

>100_bases
TAATTTAATTTTATATTTAATTATTACTGTACATCTTTTGTAGTTAGCTTTATTCTTAAATTGAAATATGTATAAAACAT
AGAAAGAAGGACGTTTTAAC

Downstream 100 bases:

>100_bases
AATATTTAAATTAGTGCTCGAATCTCATTGATTTGGGCGCTTTTTAATTTGTATTTAAAATCAACCTTTGCTAAATCAAG
ACTCCCTTTTTAAAATACGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MENTVKYRKFILPIVVGLLIWALTPFKPDAVDPTAWYMFAIFVATIIACITQPMPIGAVSIIGFTIMVLVGIVDMKTAVA
GFGNNSIWLIAMAFFISRGFVKTGLGRRIALHFVKLFGKKTLGLAYSIVGVDLILAPATPSNTARAGGIMFPIIKSLSES
FGSKPKDGSARKMGAFLVFTEFQGNLITAAMFLTAMAGNPLAQNLASSTSNVHITWMNWFLAALVPGLVSLIVVPFIIYK
IYPPTVKETPNAKSWAENELATMGKIALAEKFMIGIFVIALTLWIVGSFIHIDATLTAFIALALLLLTGVLTWQDILNET
GAWNTLVWFSVLVLMADQLNKLGFIPWLSKSIATSLGGLSWPIVLVILILFYFYSHYLFASSTAHISAMYAALLGVAIAA
GAPPLFSALMLGFFGNLLASTTHYSSGPAPILFSSGYVTQKRWWTMNLILGFVYFIIWIGLGSLWMKVIGIF

Sequences:

>Translated_472_residues
MENTVKYRKFILPIVVGLLIWALTPFKPDAVDPTAWYMFAIFVATIIACITQPMPIGAVSIIGFTIMVLVGIVDMKTAVA
GFGNNSIWLIAMAFFISRGFVKTGLGRRIALHFVKLFGKKTLGLAYSIVGVDLILAPATPSNTARAGGIMFPIIKSLSES
FGSKPKDGSARKMGAFLVFTEFQGNLITAAMFLTAMAGNPLAQNLASSTSNVHITWMNWFLAALVPGLVSLIVVPFIIYK
IYPPTVKETPNAKSWAENELATMGKIALAEKFMIGIFVIALTLWIVGSFIHIDATLTAFIALALLLLTGVLTWQDILNET
GAWNTLVWFSVLVLMADQLNKLGFIPWLSKSIATSLGGLSWPIVLVILILFYFYSHYLFASSTAHISAMYAALLGVAIAA
GAPPLFSALMLGFFGNLLASTTHYSSGPAPILFSSGYVTQKRWWTMNLILGFVYFIIWIGLGSLWMKVIGIF
>Mature_472_residues
MENTVKYRKFILPIVVGLLIWALTPFKPDAVDPTAWYMFAIFVATIIACITQPMPIGAVSIIGFTIMVLVGIVDMKTAVA
GFGNNSIWLIAMAFFISRGFVKTGLGRRIALHFVKLFGKKTLGLAYSIVGVDLILAPATPSNTARAGGIMFPIIKSLSES
FGSKPKDGSARKMGAFLVFTEFQGNLITAAMFLTAMAGNPLAQNLASSTSNVHITWMNWFLAALVPGLVSLIVVPFIIYK
IYPPTVKETPNAKSWAENELATMGKIALAEKFMIGIFVIALTLWIVGSFIHIDATLTAFIALALLLLTGVLTWQDILNET
GAWNTLVWFSVLVLMADQLNKLGFIPWLSKSIATSLGGLSWPIVLVILILFYFYSHYLFASSTAHISAMYAALLGVAIAA
GAPPLFSALMLGFFGNLLASTTHYSSGPAPILFSSGYVTQKRWWTMNLILGFVYFIIWIGLGSLWMKVIGIF

Specific function: Might be a malate transporter [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family [H]

Homologues:

Organism=Escherichia coli, GI1786829, Length=446, Percent_Identity=37.6681614349776, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI1789444, Length=488, Percent_Identity=36.6803278688525, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1786986, Length=445, Percent_Identity=37.0786516853933, Blast_Score=287, Evalue=8e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 51356; Mature: 51356

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENTVKYRKFILPIVVGLLIWALTPFKPDAVDPTAWYMFAIFVATIIACITQPMPIGAVS
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHH
IIGFTIMVLVGIVDMKTAVAGFGNNSIWLIAMAFFISRGFVKTGLGRRIALHFVKLFGKK
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCH
TLGLAYSIVGVDLILAPATPSNTARAGGIMFPIIKSLSESFGSKPKDGSARKMGAFLVFT
HHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCEEEEEE
EFQGNLITAAMFLTAMAGNPLAQNLASSTSNVHITWMNWFLAALVPGLVSLIVVPFIIYK
ECCCCHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
IYPPTVKETPNAKSWAENELATMGKIALAEKFMIGIFVIALTLWIVGSFIHIDATLTAFI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALALLLLTGVLTWQDILNETGAWNTLVWFSVLVLMADQLNKLGFIPWLSKSIATSLGGLS
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCH
WPIVLVILILFYFYSHYLFASSTAHISAMYAALLGVAIAAGAPPLFSALMLGFFGNLLAS
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TTHYSSGPAPILFSSGYVTQKRWWTMNLILGFVYFIIWIGLGSLWMKVIGIF
CCCCCCCCCCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENTVKYRKFILPIVVGLLIWALTPFKPDAVDPTAWYMFAIFVATIIACITQPMPIGAVS
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHH
IIGFTIMVLVGIVDMKTAVAGFGNNSIWLIAMAFFISRGFVKTGLGRRIALHFVKLFGKK
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCH
TLGLAYSIVGVDLILAPATPSNTARAGGIMFPIIKSLSESFGSKPKDGSARKMGAFLVFT
HHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCEEEEEE
EFQGNLITAAMFLTAMAGNPLAQNLASSTSNVHITWMNWFLAALVPGLVSLIVVPFIIYK
ECCCCHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
IYPPTVKETPNAKSWAENELATMGKIALAEKFMIGIFVIALTLWIVGSFIHIDATLTAFI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALALLLLTGVLTWQDILNETGAWNTLVWFSVLVLMADQLNKLGFIPWLSKSIATSLGGLS
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCH
WPIVLVILILFYFYSHYLFASSTAHISAMYAALLGVAIAAGAPPLFSALMLGFFGNLLAS
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TTHYSSGPAPILFSSGYVTQKRWWTMNLILGFVYFIIWIGLGSLWMKVIGIF
CCCCCCCCCCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 12949159 [H]