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The map label for this gene is icaC

Identifier: 15928255

GI number: 15928255

Start: 2772860

End: 2773912

Strand: Direct

Name: icaC

Synonym: SA2462

Alternate gene names: 15928255

Gene position: 2772860-2773912 (Clockwise)

Preceding gene: 15928254

Following gene: 15928256

Centisome position: 98.51

GC content: 27.16

Gene sequence:

>1053_bases
ATGAAAAAGATTAGACTTGAACTCGTATATTTACGTGCTATTATATGTGCAATTATTATTATCACACATTTACTTACACA
AATTACTTTAAAACATGAAAATATGGAGGGAGGATCCTTAGTATTACAATTTTACATTCGTAATATTGTGATTTTTGGTA
CACCTTGCTTTATTATCTTGTCACAGTTACTGACAACCTTGAATTACCAAAAAGTCACCTATAGATACTTAACTACACGC
GTAAAATATATACTTATTCCTTACATATTAATGGGATTGTTTTACAGTTATAGTGAATCATTATTAACAGATTCAAGTTT
CAATAAACAATTCATTGAAAATGTCCTATTAGGTCAATGGTATGGCTATTTTATCGTTGTTATCATGCAATTCTTTATTT
TGAGTTATATCATTTTTAAAATTAACTATAACCTATTCAACAGTAAAATATTATTATTGTTATCTTTTATTTTACAGCAA
TCATTTTTATATTACTTTACGAACAACACAGCGTTTCACGATACCGTGCTACACTATTATCCATTAAGTGAAAACACTAT
AATATTCGGATGGATTTTTTATTTCTTTTTAGGTGCATATATGGGTTATAACTACGAACGTGTATTAAATTTCTTAGAAC
GTTATTTAGTTATTATGATTGTATTAGCTGTAGCTACTTATTTTGTGTTTATTGCGTTAGCAAATGGAGACTATTGGAAC
GTTACCAGCTTTTCATATTCATTAACACCATATAATAGTATTATGTTTATTGTTATCTTGGGTATTTGCACGCATTTTAA
AACAATGTTATTTAATACGATTCAAATGATTAGTGCTTTCTCATTCTTTATTTATTTATTACATCCAATCATTCTAGACT
CATTGTTTGCATATACAAATATATTTGAGGATAATACAATGGTCTTTCTAGCGATATCACTACTATTCATTTTAGGGTTA
TGTATAGGTGTCGGTATGATATTGCGTGAATTCTATATCTTTAGGTTTATTATTGGAAAACAACCATATAAATTGAACAT
TAATGCTTATTAA

Upstream 100 bases:

>100_bases
GAAAAAGCAGTCACTCCGAACTCCAATGATTATTACATCCCTAGAATATTAATTAGTGATGATGCTTTTGAGCATTTAAT
TAAGAGATGGGACGGATTCC

Downstream 100 bases:

>100_bases
TTATTAAGCTATGTTAAAAACACGCGGTGGGCGAAATCAGTTTGAATTGACTGACTTCGTTTTACCGCGTGTTTAATAAT
GTTATACATATATTCTAATT

Product: intercellular adhesion protein C

Products: NA

Alternate protein names: PGA export protein; Poly-beta-1,6-GlcNAc export protein; Biofilm polysaccharide intercellular adhesin export protein; Biofilm PIA export protein; Intercellular adhesion protein C

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKKIRLELVYLRAIICAIIIITHLLTQITLKHENMEGGSLVLQFYIRNIVIFGTPCFIILSQLLTTLNYQKVTYRYLTTR
VKYILIPYILMGLFYSYSESLLTDSSFNKQFIENVLLGQWYGYFIVVIMQFFILSYIIFKINYNLFNSKILLLLSFILQQ
SFLYYFTNNTAFHDTVLHYYPLSENTIIFGWIFYFFLGAYMGYNYERVLNFLERYLVIMIVLAVATYFVFIALANGDYWN
VTSFSYSLTPYNSIMFIVILGICTHFKTMLFNTIQMISAFSFFIYLLHPIILDSLFAYTNIFEDNTMVFLAISLLFILGL
CIGVGMILREFYIFRFIIGKQPYKLNINAY

Sequences:

>Translated_350_residues
MKKIRLELVYLRAIICAIIIITHLLTQITLKHENMEGGSLVLQFYIRNIVIFGTPCFIILSQLLTTLNYQKVTYRYLTTR
VKYILIPYILMGLFYSYSESLLTDSSFNKQFIENVLLGQWYGYFIVVIMQFFILSYIIFKINYNLFNSKILLLLSFILQQ
SFLYYFTNNTAFHDTVLHYYPLSENTIIFGWIFYFFLGAYMGYNYERVLNFLERYLVIMIVLAVATYFVFIALANGDYWN
VTSFSYSLTPYNSIMFIVILGICTHFKTMLFNTIQMISAFSFFIYLLHPIILDSLFAYTNIFEDNTMVFLAISLLFILGL
CIGVGMILREFYIFRFIIGKQPYKLNINAY
>Mature_350_residues
MKKIRLELVYLRAIICAIIIITHLLTQITLKHENMEGGSLVLQFYIRNIVIFGTPCFIILSQLLTTLNYQKVTYRYLTTR
VKYILIPYILMGLFYSYSESLLTDSSFNKQFIENVLLGQWYGYFIVVIMQFFILSYIIFKINYNLFNSKILLLLSFILQQ
SFLYYFTNNTAFHDTVLHYYPLSENTIIFGWIFYFFLGAYMGYNYERVLNFLERYLVIMIVLAVATYFVFIALANGDYWN
VTSFSYSLTPYNSIMFIVILGICTHFKTMLFNTIQMISAFSFFIYLLHPIILDSLFAYTNIFEDNTMVFLAISLLFILGL
CIGVGMILREFYIFRFIIGKQPYKLNINAY

Specific function: Presumably involved in the export of the biofilm adhesin polysaccharide poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA) across the cell membrane

COG id: COG3936

COG function: function code G; Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyltransferase 3 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ICAC_STAA8 (Q9RQP6)

Other databases:

- EMBL:   AF086783
- EMBL:   CP000253
- PIR:   E90075
- RefSeq:   YP_501454.1
- STRING:   Q9RQP6
- EnsemblBacteria:   EBSTAT00000029523
- GeneID:   3921487
- GenomeReviews:   CP000253_GR
- KEGG:   sao:SAOUHSC_03005
- eggNOG:   COG3936
- GeneTree:   EBGT00050000025406
- HOGENOM:   HBG535610
- OMA:   AFIFISE
- ProtClustDB:   CLSK886143
- GO:   GO:0006810
- InterPro:   IPR002656

Pfam domain/function: PF01757 Acyl_transf_3

EC number: NA

Molecular weight: Translated: 41345; Mature: 41345

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10246e44)-; HASH(0x1041caf8)-; HASH(0x108e06b4)-; HASH(0x10631384)-; HASH(0x10d7502c)-; HASH(0x10a17474)-; HASH(0x107e3dd4)-; HASH(0x102359f0)-; HASH(0x10d4cc28)-; HASH(0x107808fc)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIRLELVYLRAIICAIIIITHLLTQITLKHENMEGGSLVLQFYIRNIVIFGTPCFIIL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
SQLLTTLNYQKVTYRYLTTRVKYILIPYILMGLFYSYSESLLTDSSFNKQFIENVLLGQW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
YGYFIVVIMQFFILSYIIFKINYNLFNSKILLLLSFILQQSFLYYFTNNTAFHDTVLHYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHEEEE
PLSENTIIFGWIFYFFLGAYMGYNYERVLNFLERYLVIMIVLAVATYFVFIALANGDYWN
ECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VTSFSYSLTPYNSIMFIVILGICTHFKTMLFNTIQMISAFSFFIYLLHPIILDSLFAYTN
EEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFEDNTMVFLAISLLFILGLCIGVGMILREFYIFRFIIGKQPYKLNINAY
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCH
>Mature Secondary Structure
MKKIRLELVYLRAIICAIIIITHLLTQITLKHENMEGGSLVLQFYIRNIVIFGTPCFIIL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
SQLLTTLNYQKVTYRYLTTRVKYILIPYILMGLFYSYSESLLTDSSFNKQFIENVLLGQW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
YGYFIVVIMQFFILSYIIFKINYNLFNSKILLLLSFILQQSFLYYFTNNTAFHDTVLHYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHEEEE
PLSENTIIFGWIFYFFLGAYMGYNYERVLNFLERYLVIMIVLAVATYFVFIALANGDYWN
ECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VTSFSYSLTPYNSIMFIVILGICTHFKTMLFNTIQMISAFSFFIYLLHPIILDSLFAYTN
EEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFEDNTMVFLAISLLFILGLCIGVGMILREFYIFRFIIGKQPYKLNINAY
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10496925