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The map label for this gene is TRAP

Identifier: 15927409

GI number: 15927409

Start: 1887575

End: 1888078

Strand: Direct

Name: TRAP

Synonym: SA1653

Alternate gene names: 15927409

Gene position: 1887575-1888078 (Clockwise)

Preceding gene: 15927397

Following gene: 15927412

Centisome position: 67.06

GC content: 31.35

Gene sequence:

>504_bases
ATGAAGAAACTATATACATCTTATGGCACTTATGGATTTTTACATCAAATAAAAATCAATAACCCGACCCATCAACTATT
CCAATTTTCAGCATCAGATACTTCAGTTATTTTTGAAGAAACTGATGGTGAGACTGTTTTAAAATCACCTTCAATATATG
AAGTTATTAAAGAAATTGGTGAATTCAGTGAACATCATTTCTATTGTGCAATCTTCATTCCTTCAACAGAAGATCATGCA
TATCAACTTGAAAAGAAACTGATTAGTGTAGACGATAATTTCAGAAACTTTGGTGGCTTTAAAAGCTATCGTTTGTTAAG
ACCTGCTAAAGGTACAACATATAAAATTTATTTCGGATTTGCTGATCGACATGCATACGAAGACTTTAAGCAATCTGATG
CCTTTAATGACCATTTTTCAAAAGACGCATTAAGTCATTACTTTGGTTCAAGCGGACAACATTCAAGTTATTTTGAAAGA
TATCTATACCCAATAAAAGAATAG

Upstream 100 bases:

>100_bases
TCTCGCAAGATTCATTATAGTAATTTTAATCAATTATTAATAGTGGTAATGACTAGTTTATCATCGTATAATAAATAAAA
ACATAAGGGGGACCTTTCAT

Downstream 100 bases:

>100_bases
ACTCGAAGAAAACTTCCATTGGTTATGCTGTTAACGTATAGATGCTAATGTAATCTGAACGCCGTATCATTTGGCGTTCA
ACATTACATGCACCTTTACA

Product: signal transduction protein TRAP

Products: NA

Alternate protein names: Target of RNAIII-activating protein

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MKKLYTSYGTYGFLHQIKINNPTHQLFQFSASDTSVIFEETDGETVLKSPSIYEVIKEIGEFSEHHFYCAIFIPSTEDHA
YQLEKKLISVDDNFRNFGGFKSYRLLRPAKGTTYKIYFGFADRHAYEDFKQSDAFNDHFSKDALSHYFGSSGQHSSYFER
YLYPIKE

Sequences:

>Translated_167_residues
MKKLYTSYGTYGFLHQIKINNPTHQLFQFSASDTSVIFEETDGETVLKSPSIYEVIKEIGEFSEHHFYCAIFIPSTEDHA
YQLEKKLISVDDNFRNFGGFKSYRLLRPAKGTTYKIYFGFADRHAYEDFKQSDAFNDHFSKDALSHYFGSSGQHSSYFER
YLYPIKE
>Mature_167_residues
MKKLYTSYGTYGFLHQIKINNPTHQLFQFSASDTSVIFEETDGETVLKSPSIYEVIKEIGEFSEHHFYCAIFIPSTEDHA
YQLEKKLISVDDNFRNFGGFKSYRLLRPAKGTTYKIYFGFADRHAYEDFKQSDAFNDHFSKDALSHYFGSSGQHSSYFER
YLYPIKE

Specific function: Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the exp

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane. Note=Membrane-associated

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TRAP family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRAP_STAA3 (Q2FFR1)

Other databases:

- EMBL:   CP000255
- RefSeq:   YP_494467.1
- STRING:   Q2FFR1
- EnsemblBacteria:   EBSTAT00000037976
- GeneID:   3912928
- GenomeReviews:   CP000255_GR
- KEGG:   saa:SAUSA300_1784
- eggNOG:   NOG145299
- GeneTree:   EBGT00050000025290
- HOGENOM:   HBG693144
- OMA:   TAYEDFK
- ProtClustDB:   CLSK885591
- GO:   GO:0005737
- GO:   GO:0016020
- GO:   GO:0009405
- InterPro:   IPR007138
- InterPro:   IPR011008

Pfam domain/function: PF03992 ABM; SSF54909 Dimer_A_B_barrel

EC number: NA

Molecular weight: Translated: 19548; Mature: 19548

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLYTSYGTYGFLHQIKINNPTHQLFQFSASDTSVIFEETDGETVLKSPSIYEVIKEIG
CCCEECCCCCCEEEEEEEECCCHHHHEEECCCCCEEEEECCCCCEEECCCCHHHHHHHHH
EFSEHHFYCAIFIPSTEDHAYQLEKKLISVDDNFRNFGGFKSYRLLRPAKGTTYKIYFGF
HHCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCHHCCCCCCEEEECCCCCCEEEEEEEC
ADRHAYEDFKQSDAFNDHFSKDALSHYFGSSGQHSSYFERYLYPIKE
CHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MKKLYTSYGTYGFLHQIKINNPTHQLFQFSASDTSVIFEETDGETVLKSPSIYEVIKEIG
CCCEECCCCCCEEEEEEEECCCHHHHEEECCCCCEEEEECCCCCEEECCCCHHHHHHHHH
EFSEHHFYCAIFIPSTEDHAYQLEKKLISVDDNFRNFGGFKSYRLLRPAKGTTYKIYFGF
HHCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCHHCCCCCCEEEECCCCCCEEEEEEEC
ADRHAYEDFKQSDAFNDHFSKDALSHYFGSSGQHSSYFERYLYPIKE
CHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA