Click here to switch to the map view.

The map label for this gene is infC

Identifier: 15927259

GI number: 15927259

Start: 1711348

End: 1711866

Strand: Reverse

Name: infC

Synonym: SA1504

Alternate gene names: 15927259

Gene position: 1711866-1711348 (Counterclockwise)

Preceding gene: 15927260

Following gene: 15927258

Centisome position: 60.82

GC content: 34.3

Gene sequence:

>519_bases
ATAGCAAAAGATCAAACTCAAATCAATGACAAAATTCGTGCAAAAGAATTACGTTTAATCGGTCAAGATGGTGAACAAAT
TGGTGTTAAATCAAAGCGTGAAGCTTTAGAAATGGCTGAACGTGTAGATTTAGACTTAGTGGTCGTTGCACCGAATGCGA
AACCACCAGTTGCAAGAATTATGGATTACGGTAAATTCAAATTCGAACAACAGAAAAAAGAAAAAGAAATGAAAAAGAAA
CAAAAAATTATCAATGTTAAAGAAATTCGTTTAAGTCCAACAATTGAGGAACATGATTTCCAAACTAAGTTGAAAAACGG
ACGTAAATTCTTAACTAAAGGCGATAAATGTAAAGTATCTATTCGTTTCAGAGGGCGTGCCATTACGCATAAGGAAATTG
GTCAACGTGTGCTAGAAAAATATGCAGATGAATGCAAAGATATAGCAACAGTTGAACAAAAACCTAAAATGGACGGGCGT
CAAATGTTTATCATGTTAGCGCCAACAGCTGAAAAATAA

Upstream 100 bases:

>100_bases
CACATTACACATAACTGTGTATAAGGAAGAGCGGGTATTTTATACCTGCTCTTCCTTTTTGCTTGGTGCAAATTTCGTAA
AAATTTTGGAGGTGTCAACC

Downstream 100 bases:

>100_bases
TTAAAGCTATTACAGGAGGACTTATATTATGCCAAAAATGAAAACTCACCGCGGAGCAGCTAAACGTGTTAAAAGAACTG
CTTCAGGTCAATTAAAACGT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MAKDQTQINDKIRAKELRLIGQDGEQIGVKSKREALEMAERVDLDLVVVAPNAKPPVARIMDYGKFKFEQQKKEKEMKKK
QKIINVKEIRLSPTIEEHDFQTKLKNGRKFLTKGDKCKVSIRFRGRAITHKEIGQRVLEKYADECKDIATVEQKPKMDGR
QMFIMLAPTAEK

Sequences:

>Translated_172_residues
MAKDQTQINDKIRAKELRLIGQDGEQIGVKSKREALEMAERVDLDLVVVAPNAKPPVARIMDYGKFKFEQQKKEKEMKKK
QKIINVKEIRLSPTIEEHDFQTKLKNGRKFLTKGDKCKVSIRFRGRAITHKEIGQRVLEKYADECKDIATVEQKPKMDGR
QMFIMLAPTAEK
>Mature_171_residues
AKDQTQINDKIRAKELRLIGQDGEQIGVKSKREALEMAERVDLDLVVVAPNAKPPVARIMDYGKFKFEQQKKEKEMKKKQ
KIINVKEIRLSPTIEEHDFQTKLKNGRKFLTKGDKCKVSIRFRGRAITHKEIGQRVLEKYADECKDIATVEQKPKMDGRQ
MFIMLAPTAEK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=53.0487804878049, Blast_Score=162, Evalue=9e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19913; Mature: 19781

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDQTQINDKIRAKELRLIGQDGEQIGVKSKREALEMAERVDLDLVVVAPNAKPPVARI
CCCCCHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHH
MDYGKFKFEQQKKEKEMKKKQKIINVKEIRLSPTIEEHDFQTKLKNGRKFLTKGDKCKVS
HHCCCHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCHHHHHHHHHCCCEECCCCCEEEEE
IRFRGRAITHKEIGQRVLEKYADECKDIATVEQKPKMDGRQMFIMLAPTAEK
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
AKDQTQINDKIRAKELRLIGQDGEQIGVKSKREALEMAERVDLDLVVVAPNAKPPVARI
CCCCHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHH
MDYGKFKFEQQKKEKEMKKKQKIINVKEIRLSPTIEEHDFQTKLKNGRKFLTKGDKCKVS
HHCCCHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCHHHHHHHHHCCCEECCCCCEEEEE
IRFRGRAITHKEIGQRVLEKYADECKDIATVEQKPKMDGRQMFIMLAPTAEK
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA