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The map label for this gene is ruvA

Identifier: 15927222

GI number: 15927222

Start: 1677328

End: 1677930

Strand: Reverse

Name: ruvA

Synonym: SA1468

Alternate gene names: 15927222

Gene position: 1677930-1677328 (Counterclockwise)

Preceding gene: 15927223

Following gene: 15927221

Centisome position: 59.61

GC content: 33.5

Gene sequence:

>603_bases
ATGTACGCGTATGTCAAAGGTAAGTTAACACATTTATATCCTACACACGTAGTTGTTGAAACTGCTGGTGTTGGTTATGA
AATTCAAACACCAAATTCTTATCGTTTTCAAAAGCATCTAGATCATGAAGTTTTAATTCGTACATCTTTAATTGTTCGTG
AAGATGCACAATTATTGTATGGATTTAGTAGTGAAGAAGAGAAAGATATGTTCTTGAGTTTAATTAAAGTTACTGGTATT
GGTCCGAAATCAGCTTTAGCTATTTTAGCGACAAGTACGCCTAATGAAGTAAAACGTGCCATTGAAAATGAAAATGATAC
GTATTTAACTAAATTCCCAGGAATTGGTAAGAAAACGGCAAGACAGATTGTCTTAGATTTAAAAGGTAAAGTGAAAATCA
CTGAAGAAGATAGCGATTCATTATTACAAGTAGACGCTACTTCGACGGTGCAAGATCAATTCGTGCAAGAAGCAATGTTA
GCGTTAGAAGCATTAGGTTATTCTAAACGAGAGCTTGCAAAAGTTGAGAAAACGTTAAATAAAAATAAATATGACTCAGT
TGATGAAGCTGTTAAGGCAGGTCTTCAATTAGTTGTATCTTAA

Upstream 100 bases:

>100_bases
AAAGAAACTTCAGTAGAAGATGTTATTGGTGCTTTGAGAAATTTAGATTATGTATCAAAAGTAGAATTAATTAGTATGAG
TATGTAAGGATGTGCCTATA

Downstream 100 bases:

>100_bases
TTTTAAATAGATTAATAGGGGAAGTGTTGTCATGAATGAGCGTATGGTTGATCAATCAATGCATAGTGAAGAAACTGATT
TCGAATTGTCGCTTAGACCT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MYAYVKGKLTHLYPTHVVVETAGVGYEIQTPNSYRFQKHLDHEVLIRTSLIVREDAQLLYGFSSEEEKDMFLSLIKVTGI
GPKSALAILATSTPNEVKRAIENENDTYLTKFPGIGKKTARQIVLDLKGKVKITEEDSDSLLQVDATSTVQDQFVQEAML
ALEALGYSKRELAKVEKTLNKNKYDSVDEAVKAGLQLVVS

Sequences:

>Translated_200_residues
MYAYVKGKLTHLYPTHVVVETAGVGYEIQTPNSYRFQKHLDHEVLIRTSLIVREDAQLLYGFSSEEEKDMFLSLIKVTGI
GPKSALAILATSTPNEVKRAIENENDTYLTKFPGIGKKTARQIVLDLKGKVKITEEDSDSLLQVDATSTVQDQFVQEAML
ALEALGYSKRELAKVEKTLNKNKYDSVDEAVKAGLQLVVS
>Mature_200_residues
MYAYVKGKLTHLYPTHVVVETAGVGYEIQTPNSYRFQKHLDHEVLIRTSLIVREDAQLLYGFSSEEEKDMFLSLIKVTGI
GPKSALAILATSTPNEVKRAIENENDTYLTKFPGIGKKTARQIVLDLKGKVKITEEDSDSLLQVDATSTVQDQFVQEAML
ALEALGYSKRELAKVEKTLNKNKYDSVDEAVKAGLQLVVS

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=203, Percent_Identity=35.4679802955665, Blast_Score=125, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_STAA1 (A7X358)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442219.1
- ProteinModelPortal:   A7X358
- SMR:   A7X358
- STRING:   A7X358
- EnsemblBacteria:   EBSTAT00000003364
- GeneID:   5559850
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1629
- eggNOG:   COG0632
- GeneTree:   EBGT00050000023787
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- ProtClustDB:   PRK00116
- BioCyc:   SAUR418127:SAHV_1629-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 22282; Mature: 22282

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYAYVKGKLTHLYPTHVVVETAGVGYEIQTPNSYRFQKHLDHEVLIRTSLIVREDAQLLY
CEEEEECCEEEECCCEEEEEECCCCEEEECCCCCHHHHHCCHHHHHHHHHHHCCCCHHEE
GFSSEEEKDMFLSLIKVTGIGPKSALAILATSTPNEVKRAIENENDTYLTKFPGIGKKTA
CCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHCCCCCEEEEECCCCCHHHH
RQIVLDLKGKVKITEEDSDSLLQVDATSTVQDQFVQEAMLALEALGYSKRELAKVEKTLN
HHHHEECCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
KNKYDSVDEAVKAGLQLVVS
CCCCCCHHHHHHHHHHEECC
>Mature Secondary Structure
MYAYVKGKLTHLYPTHVVVETAGVGYEIQTPNSYRFQKHLDHEVLIRTSLIVREDAQLLY
CEEEEECCEEEECCCEEEEEECCCCEEEECCCCCHHHHHCCHHHHHHHHHHHCCCCHHEE
GFSSEEEKDMFLSLIKVTGIGPKSALAILATSTPNEVKRAIENENDTYLTKFPGIGKKTA
CCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHCCCCCEEEEECCCCCHHHH
RQIVLDLKGKVKITEEDSDSLLQVDATSTVQDQFVQEAMLALEALGYSKRELAKVEKTLN
HHHHEECCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
KNKYDSVDEAVKAGLQLVVS
CCCCCCHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA