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The map label for this gene is dapD

Identifier: 15926977

GI number: 15926977

Start: 1403636

End: 1404355

Strand: Direct

Name: dapD

Synonym: SA1229

Alternate gene names: 15926977

Gene position: 1403636-1404355 (Clockwise)

Preceding gene: 15926976

Following gene: 15926978

Centisome position: 49.87

GC content: 38.19

Gene sequence:

>720_bases
ATGGTACAACATTTAACAGCTGAAGAAATTATTCAATATATAAGTGATGCTAAAAAGTCTACACCAATAAAAGTATATTT
AAATGGTAATTTTGAAGGCATCACATACCCAGAAAGTTTTAAAGTATTTGGTTCAGAACAATCTAAAGTAATCTTTTGTG
AAGCGGATGATTGGAAACCTTTTTACGAAGCATATGGTAGTCAATTCGAAGATATAGAAATTGAAATGGATCGTCGCAAT
TCTGCCATTCCATTAAAAGACTTAACAAATACGAATGCACGTATTGAACCAGGTGCATTTATTAGAGAACAAGCCATTAT
TGAAGATGGTGCTGTCGTTATGATGGGCGCAACAATTAATATTGGCGCAGTCGTTGGCGAAGGTACAATGATTGATATGA
ATGCTACTCTCGGTGGTCGTGCTACAACTGGTAAAAATGTACATGTAGGGGCTGGCGCAGTATTGGCAGGTGTGATTGAA
CCCCCTAGTGCATCACCAGTTATAATCGAGGATGATGTATTAATCGGTGCAAATGCAGTTATTTTAGAAGGTGTACGTGT
TGGTAAAGGTGCTATTGTTGCAGCTGGCGCGATTGTGACACAAGATGTACCAGCTGGTGCAGTTGTTGCTGGTACACCTG
CAAAAGTGATTAAGCAAGCTTCTGAAGTACAAGATACTAAAAAAGAGATTGTAGCAGCATTAAGAAAACTGAATGACTAG

Upstream 100 bases:

>100_bases
CGAATGGTGCTATACAAGCAGCAGAACGCTTAGTTAATAAACCAAACGGCTTTTATACGTTTGACAACTTATAAACATAT
TAAAGGAGATCGATTATTTT

Downstream 100 bases:

>100_bases
TGACGTCAACGTATAATAATTTCAAGGTTGAGATACGATTATGTCTCAACCTTATTGTTTATCATTGAATAAACTTATGA
TCACAAATTTCGAAATACGT

Product: tetrahydrodipicolinate acetyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-acetyltransferase; THP acetyltransferase; Tetrahydropicolinate acetylase

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MVQHLTAEEIIQYISDAKKSTPIKVYLNGNFEGITYPESFKVFGSEQSKVIFCEADDWKPFYEAYGSQFEDIEIEMDRRN
SAIPLKDLTNTNARIEPGAFIREQAIIEDGAVVMMGATINIGAVVGEGTMIDMNATLGGRATTGKNVHVGAGAVLAGVIE
PPSASPVIIEDDVLIGANAVILEGVRVGKGAIVAAGAIVTQDVPAGAVVAGTPAKVIKQASEVQDTKKEIVAALRKLND

Sequences:

>Translated_239_residues
MVQHLTAEEIIQYISDAKKSTPIKVYLNGNFEGITYPESFKVFGSEQSKVIFCEADDWKPFYEAYGSQFEDIEIEMDRRN
SAIPLKDLTNTNARIEPGAFIREQAIIEDGAVVMMGATINIGAVVGEGTMIDMNATLGGRATTGKNVHVGAGAVLAGVIE
PPSASPVIIEDDVLIGANAVILEGVRVGKGAIVAAGAIVTQDVPAGAVVAGTPAKVIKQASEVQDTKKEIVAALRKLND
>Mature_239_residues
MVQHLTAEEIIQYISDAKKSTPIKVYLNGNFEGITYPESFKVFGSEQSKVIFCEADDWKPFYEAYGSQFEDIEIEMDRRN
SAIPLKDLTNTNARIEPGAFIREQAIIEDGAVVMMGATINIGAVVGEGTMIDMNATLGGRATTGKNVHVGAGAVLAGVIE
PPSASPVIIEDDVLIGANAVILEGVRVGKGAIVAAGAIVTQDVPAGAVVAGTPAKVIKQASEVQDTKKEIVAALRKLND

Specific function: Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. DapH subfamily

Homologues:

Organism=Escherichia coli, GI1786362, Length=131, Percent_Identity=41.2213740458015, Blast_Score=82, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322243, Length=139, Percent_Identity=31.6546762589928, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPH_STAA1 (A7X274)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441975.1
- ProteinModelPortal:   A7X274
- SMR:   A7X274
- STRING:   A7X274
- EnsemblBacteria:   EBSTAT00000003562
- GeneID:   5559568
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1385
- eggNOG:   COG2171
- GeneTree:   EBGT00050000024445
- HOGENOM:   HBG704071
- OMA:   KNAVIMM
- ProtClustDB:   CLSK885324
- BioCyc:   SAUR418127:SAHV_1385-MONOMER
- HAMAP:   MF_01691
- InterPro:   IPR013710
- InterPro:   IPR018357
- InterPro:   IPR019873
- InterPro:   IPR011004
- TIGRFAMs:   TIGR03532

Pfam domain/function: PF08503 DapD_N; SSF51161 Trimer_LpxA_like

EC number: =2.3.1.89

Molecular weight: Translated: 25258; Mature: 25258

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQHLTAEEIIQYISDAKKSTPIKVYLNGNFEGITYPESFKVFGSEQSKVIFCEADDWKP
CCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCEEEECCCCCEEEEEECCCCCH
FYEAYGSQFEDIEIEMDRRNSAIPLKDLTNTNARIEPGAFIREQAIIEDGAVVMMGATIN
HHHHHCCCCEEEEEEECCCCCCCCHHHCCCCCCEECCCCHHHHHHHHCCCCEEEEECEEE
IGAVVGEGTMIDMNATLGGRATTGKNVHVGAGAVLAGVIEPPSASPVIIEDDVLIGANAV
EEEEECCCEEEEEECCCCCCCCCCCEEEECCCEEEEEEECCCCCCCEEEECCEEECCCEE
ILEGVRVGKGAIVAAGAIVTQDVPAGAVVAGTPAKVIKQASEVQDTKKEIVAALRKLND
EEECEEECCCEEEEECEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVQHLTAEEIIQYISDAKKSTPIKVYLNGNFEGITYPESFKVFGSEQSKVIFCEADDWKP
CCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCEEEECCCCCEEEEEECCCCCH
FYEAYGSQFEDIEIEMDRRNSAIPLKDLTNTNARIEPGAFIREQAIIEDGAVVMMGATIN
HHHHHCCCCEEEEEEECCCCCCCCHHHCCCCCCEECCCCHHHHHHHHCCCCEEEEECEEE
IGAVVGEGTMIDMNATLGGRATTGKNVHVGAGAVLAGVIEPPSASPVIIEDDVLIGANAV
EEEEECCCEEEEEECCCCCCCCCCCEEEECCCEEEEEEECCCCCCCEEEECCEEECCCEE
ILEGVRVGKGAIVAAGAIVTQDVPAGAVVAGTPAKVIKQASEVQDTKKEIVAALRKLND
EEECEEECCCEEEEECEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA