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The map label for this gene is rocD

Identifier: 15926546

GI number: 15926546

Start: 921890

End: 923080

Strand: Direct

Name: rocD

Synonym: SA0818

Alternate gene names: 15926546

Gene position: 921890-923080 (Clockwise)

Preceding gene: 15926545

Following gene: 15926547

Centisome position: 32.75

GC content: 35.68

Gene sequence:

>1191_bases
ATGACTAAATCTGAAAAAATTATTGAGTTAACAAATCATTACGGAGCACATAATTATTTACCATTGCCAATTGTCATTTC
AGAAGCTGAAGGGGTATGGGTTAAAGATCCTGAAGGCAATAAATATATGGATATGTTATCTGCATATTCCGCTGTTAACC
AAGGTCATAGACATCCGAAAATTATTCAAGCATTAAAAGATCAAGCTGATAAAGTGACTCTAGTTTCACGTGCTTTTCAT
AGTGATAACTTAGGTGAATGGTACGAAAAAATTTGTAAACTGGCAGGTAAAGATAAAGCTTTACCAATGAATACAGGTGC
TGAAGCAGTAGAAACAGCTTTGAAAGCAGCACGACGCTGGGCATACGATGTTAAAGGAATTGAGCCAAATAAAGCAGAAA
TCATTGCATTTAATGGTAACTTCCATGGTCGAACAATGGCGCCAGTTTCATTATCTTCAGAAGCAGAATACCAACGTGGT
TATGGTCCGTTATTAGATGGATTTAGAAAAGTTGATTTTGGAGATGTAGATGCATTGAAAGCTGCAATTAATGAAAATAC
TGCAGCAGTTTTAGTAGAACCAATTCAAGGTGAAGCGGGTATAAATATACCGCCAGAAGGATATTTGAAAGCAATTAGAG
AATTATGTGATGAACATAATGTCTTATTTATTGCTGACGAAATCCAAGCAGGATTAGGTCGTTCGGGTAAATTATTTGCT
ACGGATTGGGATAATGTAAAACCTGATGTCTATATTTTAGGTAAAGCACTAGGTGGTGGTGTCTTCCCAATTTCTGTTGT
ATTAGCAGATAAAGAAGTATTAGATGTCTTTACACCTGGCTCACATGGTTCAACATTTGGTGGTAATCCACTTGCTTGTG
CTGCATCAATTGCTGCATTAGATGTTATCGTTGATGAGGATTTACCAGGGCGCTCTTTAGAATTAGGAGATTATTTTAAA
GAACAATTAAAGCAAATTGATCATCCATCAATTAAAGAAGTCCGTGGACGTGGTTTGTTTATAGGTGTGGAACTTAATGA
AAGTGCTAGACCATATTGTGAAGCTTTGAAAGAAGAAGGCTTATTATGTAAAGAAACGCATGATACTGTCATTCGTTTTG
CACCACCATTAATTATTACTAAAGAAGAATTGGACCTTGCACTTGAAAAAATAAGACATGTATTTCAATAA

Upstream 100 bases:

>100_bases
CATCTTTTTTGGTGGAAAAGTATCTGCTTTGAAAACTAATGTAATTATTTGGATAATGTTTCATGTATAATAGTTATAAA
TGATGAAAAGGGGAGATATG

Downstream 100 bases:

>100_bases
TGTCAAAAAGTTGTAACAATCAGTTTGTAAGGGCTTTAAAAAGGAATACGTTATGTTACAATATGTTTGAAAGCGAAATC
ATTAGGTAAAGAAGAGGCGA

Product: ornithine--oxo-acid transaminase

Products: NA

Alternate protein names: OAT 2; Ornithine--oxo-acid aminotransferase 2

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFH
SDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRG
YGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFA
TDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFK
EQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ

Sequences:

>Translated_396_residues
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFH
SDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRG
YGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFA
TDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFK
EQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>Mature_395_residues
TKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHS
DNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGY
GPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFAT
DWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKE
QLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ

Specific function: Catalyzes the interconversion of ornithine to glutamate semialdehyde

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily

Homologues:

Organism=Homo sapiens, GI4557809, Length=393, Percent_Identity=49.3638676844784, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI284507298, Length=294, Percent_Identity=47.2789115646259, Blast_Score=282, Evalue=4e-76,
Organism=Homo sapiens, GI13994255, Length=431, Percent_Identity=29.4663573085847, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI37574042, Length=420, Percent_Identity=28.0952380952381, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI226442709, Length=388, Percent_Identity=28.0927835051546, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI226442705, Length=420, Percent_Identity=27.3809523809524, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI24119277, Length=411, Percent_Identity=27.2506082725061, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI188536080, Length=418, Percent_Identity=24.4019138755981, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI38679950, Length=418, Percent_Identity=24.4019138755981, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI38679946, Length=418, Percent_Identity=24.4019138755981, Blast_Score=89, Evalue=5e-18,
Organism=Escherichia coli, GI145693181, Length=374, Percent_Identity=37.1657754010695, Blast_Score=258, Evalue=4e-70,
Organism=Escherichia coli, GI1789759, Length=383, Percent_Identity=37.0757180156658, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1788044, Length=379, Percent_Identity=36.1477572559367, Blast_Score=245, Evalue=3e-66,
Organism=Escherichia coli, GI1787560, Length=404, Percent_Identity=33.9108910891089, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1789016, Length=412, Percent_Identity=33.0097087378641, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1786991, Length=408, Percent_Identity=29.656862745098, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786349, Length=298, Percent_Identity=27.8523489932886, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25144271, Length=391, Percent_Identity=49.616368286445, Blast_Score=400, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI25144274, Length=270, Percent_Identity=46.6666666666667, Blast_Score=251, Evalue=6e-67,
Organism=Caenorhabditis elegans, GI71981843, Length=173, Percent_Identity=47.9768786127168, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=31.4814814814815, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI71992977, Length=421, Percent_Identity=29.4536817102138, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17541228, Length=416, Percent_Identity=25.7211538461538, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6323470, Length=410, Percent_Identity=49.0243902439024, Blast_Score=375, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6324432, Length=372, Percent_Identity=33.0645161290323, Blast_Score=196, Evalue=7e-51,
Organism=Saccharomyces cerevisiae, GI6324386, Length=406, Percent_Identity=25.8620689655172, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321456, Length=371, Percent_Identity=27.4932614555256, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21357415, Length=394, Percent_Identity=49.238578680203, Blast_Score=401, Evalue=1e-112,
Organism=Drosophila melanogaster, GI161085790, Length=431, Percent_Identity=29.6983758700696, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI28574759, Length=424, Percent_Identity=29.7169811320755, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI21356575, Length=444, Percent_Identity=26.5765765765766, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI281366494, Length=421, Percent_Identity=25.1781472684086, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24667139, Length=421, Percent_Identity=25.1781472684086, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24667143, Length=421, Percent_Identity=25.1781472684086, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OAT2_STAAC (Q5HHC8)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_185829.1
- ProteinModelPortal:   Q5HHC8
- SMR:   Q5HHC8
- STRING:   Q5HHC8
- EnsemblBacteria:   EBSTAT00000010935
- GeneID:   3237697
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL0960
- TIGR:   SACOL0960
- eggNOG:   COG4992
- GeneTree:   EBGT00050000024123
- HOGENOM:   HBG725944
- OMA:   RSNIVRD
- ProtClustDB:   PRK04073
- BioCyc:   SAUR93062:SACOL0960-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01689
- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PANTHER:   PTHR11986
- PANTHER:   PTHR11986:SF18
- TIGRFAMs:   TIGR01885

Pfam domain/function: PF00202 Aminotran_3; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.13

Molecular weight: Translated: 43418; Mature: 43287

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPK
CCCCCHHHHHHHCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHH
IIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRW
HHHHHHHCCCCEEHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
AYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALK
HHHCCCCCCCCEEEEEECCCCCCCEECCEECCCCCHHHCCCCHHHHHHHCCCCCCHHHHH
AAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFA
HHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEEE
TDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAAL
ECCCCCCCCEEEEEEHHCCCCCEEEEEEECCHHHEEECCCCCCCCCCCCHHHHHHHHHHE
DVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEG
EEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCEEEEEEEECCCCCHHHHHHHHCC
LLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
CEEECCCCCEEEECCCEEEEHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPK
CCCCHHHHHHHCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHH
IIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRW
HHHHHHHCCCCEEHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
AYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALK
HHHCCCCCCCCEEEEEECCCCCCCEECCEECCCCCHHHCCCCHHHHHHHCCCCCCHHHHH
AAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFA
HHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEEE
TDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAAL
ECCCCCCCCEEEEEEHHCCCCCEEEEEEECCHHHEEECCCCCCCCCCCCHHHHHHHHHHE
DVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEG
EEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCEEEEEEEECCCCCHHHHHHHHCC
LLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
CEEECCCCCEEEECCCEEEEHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA