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The map label for this gene is est [H]

Identifier: 15926456

GI number: 15926456

Start: 840074

End: 840814

Strand: Direct

Name: est [H]

Synonym: SA0734

Alternate gene names: 15926456

Gene position: 840074-840814 (Clockwise)

Preceding gene: 15926455

Following gene: 15926457

Centisome position: 29.84

GC content: 33.2

Gene sequence:

>741_bases
ATGCAGATAAAATTACCAAAACCTTTCTTTTTTGAAGAAGGCAAACGTGCCGTGTTATTATTACATGGATTTACAGGCAA
TTCGTCTGATGTACGTCAATTAGGTCGATTTTTACAAAAAAAGGGATATACTTCGTATGCACCACAATATGAAGGTCACG
CGGCACCACCAGAGGAAATACTGAAATCTAGTCCTTTCGTTTGGTTTAAAGATGCGTTAGATGGTTATGATTATCTTGTT
GAACAAGGTTATGATGAAATTGTTGTTGCTGGTCTATCATTAGGTGGGGATTTTGCTTTAAAATTAAGCTTAAATAGAGA
TGTAAAGGGTATTGTAACGATGTGTGCACCAATGGGTGGCAAAACTGAAGGTGCCATTTATGAAGGCTTTTTAGAGTATG
CACGTAATTTTAAAAAGTATGAAGGTAAAAATCAAGAGACTATTGATAATGAAATGGATCATTTTAAACCAACTGAAACT
TTAAAAGAACTAAGTGAAGCATTAGATACGATTAAAGATCAAGTTGATGAGGTATTTGACCCAATTTTAGTGATTCAAGT
AGAAAACGACAATATGATTGATCCACAATCCGCAAATTATATATATGACCATGTAGATTCTGATGACAAAGACATCAAGT
GGTATAGTCAATCAGGACATGTTATTACGATTGATAAAGAAAAAGAACAAGTATTTGAAGATATTTATCAATTTTTAGAG
TCATTAGACTGGTCAGAATAA

Upstream 100 bases:

>100_bases
ATGTCGGGCTTTTTTATTTATAATTAAGAATGTAATAGTTTAACAATAAGCTATGTAAAATATATAGCCTAGTTAAGTAT
GCAAAGGGAGCGTTAGATTT

Downstream 100 bases:

>100_bases
AAAGAGATTTTAACATTAGAAAGGAGGGGCATAATGAATTTAAAGCAATCAATAGAAGAGATTATTAATCAACCTGAATA
TGAACCTATGTCAGTGTCAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MQIKLPKPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYAPQYEGHAAPPEEILKSSPFVWFKDALDGYDYLV
EQGYDEIVVAGLSLGGDFALKLSLNRDVKGIVTMCAPMGGKTEGAIYEGFLEYARNFKKYEGKNQETIDNEMDHFKPTET
LKELSEALDTIKDQVDEVFDPILVIQVENDNMIDPQSANYIYDHVDSDDKDIKWYSQSGHVITIDKEKEQVFEDIYQFLE
SLDWSE

Sequences:

>Translated_246_residues
MQIKLPKPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYAPQYEGHAAPPEEILKSSPFVWFKDALDGYDYLV
EQGYDEIVVAGLSLGGDFALKLSLNRDVKGIVTMCAPMGGKTEGAIYEGFLEYARNFKKYEGKNQETIDNEMDHFKPTET
LKELSEALDTIKDQVDEVFDPILVIQVENDNMIDPQSANYIYDHVDSDDKDIKWYSQSGHVITIDKEKEQVFEDIYQFLE
SLDWSE
>Mature_246_residues
MQIKLPKPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYAPQYEGHAAPPEEILKSSPFVWFKDALDGYDYLV
EQGYDEIVVAGLSLGGDFALKLSLNRDVKGIVTMCAPMGGKTEGAIYEGFLEYARNFKKYEGKNQETIDNEMDHFKPTET
LKELSEALDTIKDQVDEVFDPILVIQVENDNMIDPQSANYIYDHVDSDDKDIKWYSQSGHVITIDKEKEQVFEDIYQFLE
SLDWSE

Specific function: Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates, with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones [H]

COG id: COG1647

COG function: function code R; Esterase/lipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012354
- InterPro:   IPR001375 [H]

Pfam domain/function: PF00326 Peptidase_S9 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 28156; Mature: 28156

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKLPKPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYAPQYEGHAAPPEEI
CCCCCCCCHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
LKSSPFVWFKDALDGYDYLVEQGYDEIVVAGLSLGGDFALKLSLNRDVKGIVTMCAPMGG
HCCCCCEEEHHHHCHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHCCCCC
KTEGAIYEGFLEYARNFKKYEGKNQETIDNEMDHFKPTETLKELSEALDTIKDQVDEVFD
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
PILVIQVENDNMIDPQSANYIYDHVDSDDKDIKWYSQSGHVITIDKEKEQVFEDIYQFLE
CEEEEEECCCCCCCCCCCCEEEECCCCCCCCEEEEECCCCEEEEECHHHHHHHHHHHHHH
SLDWSE
HCCCCC
>Mature Secondary Structure
MQIKLPKPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYAPQYEGHAAPPEEI
CCCCCCCCHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
LKSSPFVWFKDALDGYDYLVEQGYDEIVVAGLSLGGDFALKLSLNRDVKGIVTMCAPMGG
HCCCCCEEEHHHHCHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHCCCCC
KTEGAIYEGFLEYARNFKKYEGKNQETIDNEMDHFKPTETLKELSEALDTIKDQVDEVFD
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
PILVIQVENDNMIDPQSANYIYDHVDSDDKDIKWYSQSGHVITIDKEKEQVFEDIYQFLE
CEEEEEECCCCCCCCCCCCEEEECCCCCCCCEEEEECCCCEEEEECHHHHHHHHHHHHHH
SLDWSE
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1369099 [H]