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The map label for this gene is sirC

Identifier: 15925817

GI number: 15925817

Start: 125543

End: 126460

Strand: Reverse

Name: sirC

Synonym: SA0109

Alternate gene names: 15925817

Gene position: 126460-125543 (Counterclockwise)

Preceding gene: 15925818

Following gene: 15925816

Centisome position: 4.49

GC content: 37.04

Gene sequence:

>918_bases
ATGATGATTGGTTCAAGCTTTATACCATTACAACGCGTACTGATGTACTTTATAAATCCAAATGACAGTATGGATCAATT
CACTTTAGAAGTATTACGCTTACCTCGCATTACACTTGCGATTTTAGCAGGTGCCGCACTAGGAATGAGTGGTTTAATGT
TGCAAAATGTATTAAAAAATCCAATTGCCTCACCTGATATTATCGGTATCACAGGTGGTGCTAGCTTAAGTGCTGTTGTC
TTTATTGCATTTTTCAGCCATTTAACGATACATTTACTTCCACTATTTGCAGTATTAGGTGGCGCAGTTGCAATGATGAT
ACTATTAGTGTTTCAAACGAAAGGACAAATACGCCCGACAATACTCATAATCATCGGTATTTCGATGCAAACGTTGTTTA
TTGCGCTTGTCCAAGGATTACTCATTACAACGAAGCAATTATCTGCTGCCAAAGCTTATACATGGCTAGTCGGAAGTCTT
TACGGTGCTACGTTTAAAGATACAATCATTTTGGGTATGGTTATTTTAGCTGTTGTGCCGTTGTTATTTCTTGTTATACC
AAAAATGAAAATATCTATACTTGATGACCCTGTAGCGATTGGCTTAGGCTTACATGTACAACGTATGAAACTAATCCAAT
TAATCACTTCTACTATACTCGTATCTATGGCAATCAGTTTAGTAGGTAACATTGGGTTTGTCGGTTTAATCGCACCACAT
ATCGCGAAAACAATCGTTCGCGGAAGTTATGCTAAAAAGTTACTAATGTCAGCAATGATTGGTGCCATATCAATTGTTAT
TGCAGACTTAATTGGGCGTACCTTATTCTTGCCTAAAGAAGTGCCAGCAGGTGTATTTATTGCTGCTTTTGGTGCCCCAT
TCTTCATATACTTATTATTAACCGTGAAAAAGTTATAA

Upstream 100 bases:

>100_bases
AGAAAGGACGTCAACGCTTATGACCGAAAAGATTAATAAAAAAGACAATTACCATCTCATCTTCGCGTTAATCTTTTTAG
CCATCGTTTCAGTGGTAAGT

Downstream 100 bases:

>100_bases
CGATATTATTAAAACAAAATGACCTCACAACGAAGTTAGCTAAATGATTCAGTTAACTAACAGTTGCGAGGTTTTTTTAT
ACATATAGTTGTTGTTATTG

Product: lipoprotein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MMIGSSFIPLQRVLMYFINPNDSMDQFTLEVLRLPRITLAILAGAALGMSGLMLQNVLKNPIASPDIIGITGGASLSAVV
FIAFFSHLTIHLLPLFAVLGGAVAMMILLVFQTKGQIRPTILIIIGISMQTLFIALVQGLLITTKQLSAAKAYTWLVGSL
YGATFKDTIILGMVILAVVPLLFLVIPKMKISILDDPVAIGLGLHVQRMKLIQLITSTILVSMAISLVGNIGFVGLIAPH
IAKTIVRGSYAKKLLMSAMIGAISIVIADLIGRTLFLPKEVPAGVFIAAFGAPFFIYLLLTVKKL

Sequences:

>Translated_305_residues
MMIGSSFIPLQRVLMYFINPNDSMDQFTLEVLRLPRITLAILAGAALGMSGLMLQNVLKNPIASPDIIGITGGASLSAVV
FIAFFSHLTIHLLPLFAVLGGAVAMMILLVFQTKGQIRPTILIIIGISMQTLFIALVQGLLITTKQLSAAKAYTWLVGSL
YGATFKDTIILGMVILAVVPLLFLVIPKMKISILDDPVAIGLGLHVQRMKLIQLITSTILVSMAISLVGNIGFVGLIAPH
IAKTIVRGSYAKKLLMSAMIGAISIVIADLIGRTLFLPKEVPAGVFIAAFGAPFFIYLLLTVKKL
>Mature_305_residues
MMIGSSFIPLQRVLMYFINPNDSMDQFTLEVLRLPRITLAILAGAALGMSGLMLQNVLKNPIASPDIIGITGGASLSAVV
FIAFFSHLTIHLLPLFAVLGGAVAMMILLVFQTKGQIRPTILIIIGISMQTLFIALVQGLLITTKQLSAAKAYTWLVGSL
YGATFKDTIILGMVILAVVPLLFLVIPKMKISILDDPVAIGLGLHVQRMKLIQLITSTILVSMAISLVGNIGFVGLIAPH
IAKTIVRGSYAKKLLMSAMIGAISIVIADLIGRTLFLPKEVPAGVFIAAFGAPFFIYLLLTVKKL

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=277, Percent_Identity=32.129963898917, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1786347, Length=274, Percent_Identity=31.3868613138686, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786804, Length=277, Percent_Identity=33.5740072202166, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790741, Length=285, Percent_Identity=32.280701754386, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786805, Length=302, Percent_Identity=30.1324503311258, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788004, Length=296, Percent_Identity=27.027027027027, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 32653; Mature: 32653

Theoretical pI: Translated: 10.77; Mature: 10.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIGSSFIPLQRVLMYFINPNDSMDQFTLEVLRLPRITLAILAGAALGMSGLMLQNVLKN
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
PIASPDIIGITGGASLSAVVFIAFFSHLTIHLLPLFAVLGGAVAMMILLVFQTKGQIRPT
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
ILIIIGISMQTLFIALVQGLLITTKQLSAAKAYTWLVGSLYGATFKDTIILGMVILAVVP
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LLFLVIPKMKISILDDPVAIGLGLHVQRMKLIQLITSTILVSMAISLVGNIGFVGLIAPH
HHHHHHCCHHEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IAKTIVRGSYAKKLLMSAMIGAISIVIADLIGRTLFLPKEVPAGVFIAAFGAPFFIYLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHH
TVKKL
HHHCC
>Mature Secondary Structure
MMIGSSFIPLQRVLMYFINPNDSMDQFTLEVLRLPRITLAILAGAALGMSGLMLQNVLKN
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
PIASPDIIGITGGASLSAVVFIAFFSHLTIHLLPLFAVLGGAVAMMILLVFQTKGQIRPT
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
ILIIIGISMQTLFIALVQGLLITTKQLSAAKAYTWLVGSLYGATFKDTIILGMVILAVVP
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LLFLVIPKMKISILDDPVAIGLGLHVQRMKLIQLITSTILVSMAISLVGNIGFVGLIAPH
HHHHHHCCHHEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IAKTIVRGSYAKKLLMSAMIGAISIVIADLIGRTLFLPKEVPAGVFIAAFGAPFFIYLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHH
TVKKL
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]