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The map label for this gene is kdpD

Identifier: 15925774

GI number: 15925774

Start: 74179

End: 76812

Strand: Reverse

Name: kdpD

Synonym: SA0067

Alternate gene names: 15925774

Gene position: 76812-74179 (Counterclockwise)

Preceding gene: 15925779

Following gene: 15925773

Centisome position: 2.73

GC content: 36.71

Gene sequence:

>2634_bases
ATTTATTTAGGCTATAGCCCAGGGGTAGGTAAAACGTATGAAATGTTATCAAATGGTATTGATCAGTATCAAGAAGGTGC
AGATATTAAAATTGGTTATATCGAACCCCATCAACGCCCTGAAACCAATGCACTGGTTCAACAATTGCCTGAAATTTCGA
CCTCCAGCCGTAAATTTGGCAGCCACACCTTTCACTATATAGATGTCTCTAAAATCATAGAAGCTAATCCAGATGTGGTC
TTAATTGATGAACTAGCACATACAAACATTTCAAAAGAGCGCCATTTAAAACGTTATAAGGATATAGAAGAAATTCTATC
GCATGGTATCGATGTCTGGACAACACTCAACATCCAACATATCGAGAGTCTAAGCGGACAAATTGCGTTAATGACAGGTA
TTCAAGTTACAGAACGTGTGCCCGACCAATTCATTACGTCAGCAGATGCCTTTGAAGTTGTGGATATTTCACCAAATATG
TTGATTCAGCGCCTTAAAGCAGGAAAAGTATATAAAAAAGAACGCTTAGAAACAGCCTTTTCTAATTTCTTTACGTATGA
AAATCTGACAGAGCTGCGTGAACTTACACTCAGAACTGTCGCAGATATTATGAGTCAAAAAGGACAACAATATAAAACTA
AACATACCGACATTACACCGCATATTGCGGTAGCTATCAGCGGCAGTATTTATAACGAACGGGTCATACGAGAAGCAAGA
CGTGCTGCCTATAAAGAACATGCTAAATTCACAGCTGTGTATATTGATGTCTTTGAGACACCGTCAGAAAGCAGAAAACA
AGATCATTATGTCCATAAAAATCTAATGCTCGCCAAAGCGTTAGGTGCAGAAATCAAAGTGTTGTATGCACAAGATATTG
CGAAAGCGTTAACCGATTGGTGTGATCTCGCTTTTGTGACGAAGCTAGTCCTTGGACAGTCAGAACAGCCACGTTGGAAA
GATTACTTTAAACAGTCACTCATTGAACAAATTAATCACGTACCACACCATTTCAAGTTAGAAATTGTACCGATTCATTA
TATTCATTCAGACAAACCTACAAATACACCTAAGCAAGCTCAAAAATCCTCTCGTTTAACTGTAGAGATTATGAAGATGC
TTGTAATTCAAACGATCTGTGTCTTGCTCGGTATATGGGTTTACAACTTAGATAAAAGCGAATCCAGTGCCATTATCTTG
CTGATGTTCTTTATCGGTATTATCGTGCTTTCTATTTGGACCCAATCCTATTTAATCGGATTCTTTGCGTCTATCTTAAA
TGTGTTTGTTTTTAATTATTTCTTTACGGTGCCAAGATTCACTTTAGAAATGTATCGCTTTGAATATCCGATTACGTTTG
CGACCAGTATTTTTGCTAGTATCTTTACGAGTGCCATCTTAAAGAATTTAAAACATCAGCATTCCTTAACAGAACGGCAG
TTATATCGGACCAATATTATGCTGCAATTTAACCAGTCCATTAAAGAATCTTATTCAATTGAACGCTTATTAAATATTGC
TGGTGATCAGATTCATCAGCTACTCAATCAGGATGTCACGGTATTCTTAATTCAAAGTAAGAAAGTCGCTGCTTCCAACT
CATTTGGAAACAGAAGCATTTCAAGCTCAGATAAGACACATGATGCTGAGACATTGAGCTGGGTCATTGAAAATGAAAGC
CGTGCCGGTAAATTAACCGATACCTTTCCTGGCAGTAAATTTTTGTGTATTCCCATTGGCACAAATCCAGTCAAAGGTGT
GATTTCTATCCGCTTCACCGACGAAACTTACATCGACACCTATGACAATTCAATATTAGACTCTATGTTGAACGATATTA
CCCTGGCAATAGAGAATGTGGATCTATTAAAACAAACCAGACAATCCATATTGAAAGCTGAACGAGAAGCCACACGTTCA
AACTTCTTGCATTCAATTTCACATGATATTAGAACACCACTGACTTCCATTATGGGCAACTTAGATATGCTGAAATACCA
TAACGAGCATTTAAACGATCAACAACAAGCAGAACTCTTAACTGCTTCTTATGGCGAAGCACAATATCTGCATACCTTAG
TCACAAATATTTTATCTTTGACTAAGTTAGAAAGCTCTGACATTCAAATACAACGCACCCCTTATTTAGTAGAAGAACTT
CTAGAAGAATTTGAAGAAGGCCTCATACGCAGACACCAAGCAAATCATGTCATTATTGAAAATGAGGATGACGCTTCACT
CATTAATATCGACAGTAAATTAATACTGCAAGTGCTATTCAACCTTATCGATAATGCTTTAAAGCATGCAGAATCACATT
CTGAAATAAAACTGCACGTTCAACATGAAACAAACAAAATAAAATTCGAAATGATAGATTGCGGAAAAGGTATTCCAGAA
GAAGAACGTCAATTGATTTTTAATCCCTATTATTCAGGAGACAACTTTAAAGACAATAAAAAAGATAGTTTGGGATTAGG
GCTCTATTTAGTACAACTCATCTTGAAACAACACAACAGTGAATTAGAATATCAACCGAATACACCACAAGGCAGTATTT
TTTATTTTTATTTGACTGTTAATCCAATTGAAATGGAGGGAGCCATGGATGAAAACAACATTATTGGTCGTTGA

Upstream 100 bases:

>100_bases
AACAGAAAGATAAATGGATAATATGTTGTATATTAATTATGATGTGATTAAGAGGGGGTGCCTCATGGAAAGTACATAAA
AAAAAAGAGGGAAACTTACC

Downstream 100 bases:

>100_bases
AGATGATGAAGCGATTTTACATTTAATCGATGTTGCGCTAACTATGAATTATTATAAAGTGGTTACGGCGAAGACGGGGA
AAGAAGCGGACTTTCGCCTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 877; Mature: 877

Protein sequence:

>877_residues
MYLGYSPGVGKTYEMLSNGIDQYQEGADIKIGYIEPHQRPETNALVQQLPEISTSSRKFGSHTFHYIDVSKIIEANPDVV
LIDELAHTNISKERHLKRYKDIEEILSHGIDVWTTLNIQHIESLSGQIALMTGIQVTERVPDQFITSADAFEVVDISPNM
LIQRLKAGKVYKKERLETAFSNFFTYENLTELRELTLRTVADIMSQKGQQYKTKHTDITPHIAVAISGSIYNERVIREAR
RAAYKEHAKFTAVYIDVFETPSESRKQDHYVHKNLMLAKALGAEIKVLYAQDIAKALTDWCDLAFVTKLVLGQSEQPRWK
DYFKQSLIEQINHVPHHFKLEIVPIHYIHSDKPTNTPKQAQKSSRLTVEIMKMLVIQTICVLLGIWVYNLDKSESSAIIL
LMFFIGIIVLSIWTQSYLIGFFASILNVFVFNYFFTVPRFTLEMYRFEYPITFATSIFASIFTSAILKNLKHQHSLTERQ
LYRTNIMLQFNQSIKESYSIERLLNIAGDQIHQLLNQDVTVFLIQSKKVAASNSFGNRSISSSDKTHDAETLSWVIENES
RAGKLTDTFPGSKFLCIPIGTNPVKGVISIRFTDETYIDTYDNSILDSMLNDITLAIENVDLLKQTRQSILKAEREATRS
NFLHSISHDIRTPLTSIMGNLDMLKYHNEHLNDQQQAELLTASYGEAQYLHTLVTNILSLTKLESSDIQIQRTPYLVEEL
LEEFEEGLIRRHQANHVIIENEDDASLINIDSKLILQVLFNLIDNALKHAESHSEIKLHVQHETNKIKFEMIDCGKGIPE
EERQLIFNPYYSGDNFKDNKKDSLGLGLYLVQLILKQHNSELEYQPNTPQGSIFYFYLTVNPIEMEGAMDENNIIGR

Sequences:

>Translated_877_residues
MYLGYSPGVGKTYEMLSNGIDQYQEGADIKIGYIEPHQRPETNALVQQLPEISTSSRKFGSHTFHYIDVSKIIEANPDVV
LIDELAHTNISKERHLKRYKDIEEILSHGIDVWTTLNIQHIESLSGQIALMTGIQVTERVPDQFITSADAFEVVDISPNM
LIQRLKAGKVYKKERLETAFSNFFTYENLTELRELTLRTVADIMSQKGQQYKTKHTDITPHIAVAISGSIYNERVIREAR
RAAYKEHAKFTAVYIDVFETPSESRKQDHYVHKNLMLAKALGAEIKVLYAQDIAKALTDWCDLAFVTKLVLGQSEQPRWK
DYFKQSLIEQINHVPHHFKLEIVPIHYIHSDKPTNTPKQAQKSSRLTVEIMKMLVIQTICVLLGIWVYNLDKSESSAIIL
LMFFIGIIVLSIWTQSYLIGFFASILNVFVFNYFFTVPRFTLEMYRFEYPITFATSIFASIFTSAILKNLKHQHSLTERQ
LYRTNIMLQFNQSIKESYSIERLLNIAGDQIHQLLNQDVTVFLIQSKKVAASNSFGNRSISSSDKTHDAETLSWVIENES
RAGKLTDTFPGSKFLCIPIGTNPVKGVISIRFTDETYIDTYDNSILDSMLNDITLAIENVDLLKQTRQSILKAEREATRS
NFLHSISHDIRTPLTSIMGNLDMLKYHNEHLNDQQQAELLTASYGEAQYLHTLVTNILSLTKLESSDIQIQRTPYLVEEL
LEEFEEGLIRRHQANHVIIENEDDASLINIDSKLILQVLFNLIDNALKHAESHSEIKLHVQHETNKIKFEMIDCGKGIPE
EERQLIFNPYYSGDNFKDNKKDSLGLGLYLVQLILKQHNSELEYQPNTPQGSIFYFYLTVNPIEMEGAMDENNIIGR
>Mature_877_residues
MYLGYSPGVGKTYEMLSNGIDQYQEGADIKIGYIEPHQRPETNALVQQLPEISTSSRKFGSHTFHYIDVSKIIEANPDVV
LIDELAHTNISKERHLKRYKDIEEILSHGIDVWTTLNIQHIESLSGQIALMTGIQVTERVPDQFITSADAFEVVDISPNM
LIQRLKAGKVYKKERLETAFSNFFTYENLTELRELTLRTVADIMSQKGQQYKTKHTDITPHIAVAISGSIYNERVIREAR
RAAYKEHAKFTAVYIDVFETPSESRKQDHYVHKNLMLAKALGAEIKVLYAQDIAKALTDWCDLAFVTKLVLGQSEQPRWK
DYFKQSLIEQINHVPHHFKLEIVPIHYIHSDKPTNTPKQAQKSSRLTVEIMKMLVIQTICVLLGIWVYNLDKSESSAIIL
LMFFIGIIVLSIWTQSYLIGFFASILNVFVFNYFFTVPRFTLEMYRFEYPITFATSIFASIFTSAILKNLKHQHSLTERQ
LYRTNIMLQFNQSIKESYSIERLLNIAGDQIHQLLNQDVTVFLIQSKKVAASNSFGNRSISSSDKTHDAETLSWVIENES
RAGKLTDTFPGSKFLCIPIGTNPVKGVISIRFTDETYIDTYDNSILDSMLNDITLAIENVDLLKQTRQSILKAEREATRS
NFLHSISHDIRTPLTSIMGNLDMLKYHNEHLNDQQQAELLTASYGEAQYLHTLVTNILSLTKLESSDIQIQRTPYLVEEL
LEEFEEGLIRRHQANHVIIENEDDASLINIDSKLILQVLFNLIDNALKHAESHSEIKLHVQHETNKIKFEMIDCGKGIPE
EERQLIFNPYYSGDNFKDNKKDSLGLGLYLVQLILKQHNSELEYQPNTPQGSIFYFYLTVNPIEMEGAMDENNIIGR

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=875, Percent_Identity=26.4, Blast_Score=332, Evalue=4e-92,
Organism=Escherichia coli, GI1788713, Length=269, Percent_Identity=28.2527881040892, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI145693157, Length=239, Percent_Identity=26.3598326359833, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788549, Length=240, Percent_Identity=26.25, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=24.2152466367713, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1789149, Length=273, Percent_Identity=24.9084249084249, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI48994928, Length=258, Percent_Identity=25.1937984496124, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1790346, Length=217, Percent_Identity=22.5806451612903, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI87081816, Length=244, Percent_Identity=26.6393442622951, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788393, Length=205, Percent_Identity=21.4634146341463, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87082128, Length=210, Percent_Identity=24.2857142857143, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR014729
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 100612; Mature: 100612

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLGYSPGVGKTYEMLSNGIDQYQEGADIKIGYIEPHQRPETNALVQQLPEISTSSRKFG
CCCCCCCCCCHHHHHHHCCHHHHHCCCCEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCC
SHTFHYIDVSKIIEANPDVVLIDELAHTNISKERHLKRYKDIEEILSHGIDVWTTLNIQH
CCEEEEEEHHHHHCCCCCEEEEECHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCHHH
IESLSGQIALMTGIQVTERVPDQFITSADAFEVVDISPNMLIQRLKAGKVYKKERLETAF
HHHCCCCEEEEECCHHHHHCCHHHHCCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHH
SNFFTYENLTELRELTLRTVADIMSQKGQQYKTKHTDITPHIAVAISGSIYNERVIREAR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCEEEEEEECCHHHHHHHHHHH
RAAYKEHAKFTAVYIDVFETPSESRKQDHYVHKNLMLAKALGAEIKVLYAQDIAKALTDW
HHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
CDLAFVTKLVLGQSEQPRWKDYFKQSLIEQINHVPHHFKLEIVPIHYIHSDKPTNTPKQA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCCCHHHH
QKSSRLTVEIMKMLVIQTICVLLGIWVYNLDKSESSAIILLMFFIGIIVLSIWTQSYLIG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FFASILNVFVFNYFFTVPRFTLEMYRFEYPITFATSIFASIFTSAILKNLKHQHSLTERQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYRTNIMLQFNQSIKESYSIERLLNIAGDQIHQLLNQDVTVFLIQSKKVAASNSFGNRSI
HHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEECCCCCCCCCC
SSSDKTHDAETLSWVIENESRAGKLTDTFPGSKFLCIPIGTNPVKGVISIRFTDETYIDT
CCCCCCCCHHHHHEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCEEEC
YDNSILDSMLNDITLAIENVDLLKQTRQSILKAEREATRSNFLHSISHDIRTPLTSIMGN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LDMLKYHNEHLNDQQQAELLTASYGEAQYLHTLVTNILSLTKLESSDIQIQRTPYLVEEL
HHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHH
LEEFEEGLIRRHQANHVIIENEDDASLINIDSKLILQVLFNLIDNALKHAESHSEIKLHV
HHHHHHHHHHHHCCCEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
QHETNKIKFEMIDCGKGIPEEERQLIFNPYYSGDNFKDNKKDSLGLGLYLVQLILKQHNS
EECCCEEEEEEEECCCCCCCHHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
ELEYQPNTPQGSIFYFYLTVNPIEMEGAMDENNIIGR
CCCCCCCCCCCCEEEEEEEECEEEECCCCCCCCCCCC
>Mature Secondary Structure
MYLGYSPGVGKTYEMLSNGIDQYQEGADIKIGYIEPHQRPETNALVQQLPEISTSSRKFG
CCCCCCCCCCHHHHHHHCCHHHHHCCCCEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCC
SHTFHYIDVSKIIEANPDVVLIDELAHTNISKERHLKRYKDIEEILSHGIDVWTTLNIQH
CCEEEEEEHHHHHCCCCCEEEEECHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCHHH
IESLSGQIALMTGIQVTERVPDQFITSADAFEVVDISPNMLIQRLKAGKVYKKERLETAF
HHHCCCCEEEEECCHHHHHCCHHHHCCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHH
SNFFTYENLTELRELTLRTVADIMSQKGQQYKTKHTDITPHIAVAISGSIYNERVIREAR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCEEEEEEECCHHHHHHHHHHH
RAAYKEHAKFTAVYIDVFETPSESRKQDHYVHKNLMLAKALGAEIKVLYAQDIAKALTDW
HHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
CDLAFVTKLVLGQSEQPRWKDYFKQSLIEQINHVPHHFKLEIVPIHYIHSDKPTNTPKQA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCCCHHHH
QKSSRLTVEIMKMLVIQTICVLLGIWVYNLDKSESSAIILLMFFIGIIVLSIWTQSYLIG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FFASILNVFVFNYFFTVPRFTLEMYRFEYPITFATSIFASIFTSAILKNLKHQHSLTERQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYRTNIMLQFNQSIKESYSIERLLNIAGDQIHQLLNQDVTVFLIQSKKVAASNSFGNRSI
HHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEECCCCCCCCCC
SSSDKTHDAETLSWVIENESRAGKLTDTFPGSKFLCIPIGTNPVKGVISIRFTDETYIDT
CCCCCCCCHHHHHEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCEEEC
YDNSILDSMLNDITLAIENVDLLKQTRQSILKAEREATRSNFLHSISHDIRTPLTSIMGN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LDMLKYHNEHLNDQQQAELLTASYGEAQYLHTLVTNILSLTKLESSDIQIQRTPYLVEEL
HHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHH
LEEFEEGLIRRHQANHVIIENEDDASLINIDSKLILQVLFNLIDNALKHAESHSEIKLHV
HHHHHHHHHHHHCCCEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
QHETNKIKFEMIDCGKGIPEEERQLIFNPYYSGDNFKDNKKDSLGLGLYLVQLILKQHNS
EECCCEEEEEEEECCCCCCCHHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
ELEYQPNTPQGSIFYFYLTVNPIEMEGAMDENNIIGR
CCCCCCCCCCCCEEEEEEEECEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9226259; 11466286 [H]