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The map label for this gene is yrkH [H]

Identifier: 15925750

GI number: 15925750

Start: 51392

End: 52330

Strand: Reverse

Name: yrkH [H]

Synonym: SA0043

Alternate gene names: 15925750

Gene position: 52330-51392 (Counterclockwise)

Preceding gene: 15925751

Following gene: 15925749

Centisome position: 1.86

GC content: 33.12

Gene sequence:

>939_bases
TTGTTTTTCAAACAATTTTATGAAGACAATTTTTCACAAGCATCTTATTTAATTGGATGTCAACGTACAGGAGAAGCAAT
GATTATTGACCCTATACGAGATTTAACAAAATATTTAAAAGTTGCAGATAAAGAAGGATTCACAATTACTAAAGCTGCAG
AAACACATATTCATGCTGATTTTGCTTCAGGTATTAGAGATGTGGCAAATAAATTGAATGCAAGTATATACGTATCTGAT
GAAGGTAAAGATGAATTTAATTATAAAAATATGCCTAAACAAACACATTTCGTTAAGCATCAAGATATTATCTATTTAGG
AAAGATTAAATTAGAAGTCTTACACACTCCAGGCCATCCCCCTGAGAGTATTAGTTTTTTACTTACTGACGAAGGTGGGG
GTTCCAGTATACCAATGGGATTATTTAGCGGTGACTTCATCTTTGTTGGTGATGTAGGTAGACCAGATCTATTAGAAAAA
GCTGTAAATGTTGAAGGTTCTACAAAAATCGGAGCAAAACAAATGTATCAGTCCATACAATTTGCTGCAACATTACCAGA
CTATATTCAAATTTGGCCAGGTCATGGTGCAGGGAGTCCTTGTGGTAAAGCGCTAGGTTCATTACCTACAACTACTTTGG
GTTATGAGAAAATAAACAACTGGGCTTTTAATGTTAAAGATGAAACTTCATTTATCGAAACTTTAACACTCAATCAGCCA
GCTCCACCACACCATTTTTCACAAATGAAAAAAATAAATCAATTTGGTATGCAAATGTACCAACCATATAATGTTTACCC
TAGTTCAAGCAATACACAAACTGCTTTTGATCTTCGAAGTAAAGAAGCATTCCATGGTGGTCATATGCATGGAACTATCA
ATATTCCTTTTAATAAAACTTTTATAAATCAAATTGGTTGGTATTTAGATTATGACTAA

Upstream 100 bases:

>100_bases
TCGATTATGGTGGCGTAGGTACTTATATTGGACATACTGAGCAAGCAAATCATAACTTATTTATCTAATCAATAAAATCT
ATTTTAAAAAGGAGTTTTTT

Downstream 100 bases:

>100_bases
GATATTGAATTAATTGGCGATAAATCTACCGTTCAACAAGCTATTCATGCTTTACAATTAATTGGTTTTGAAAATGTAAA
AAGTTACCGTTTGCCACAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MFFKQFYEDNFSQASYLIGCQRTGEAMIIDPIRDLTKYLKVADKEGFTITKAAETHIHADFASGIRDVANKLNASIYVSD
EGKDEFNYKNMPKQTHFVKHQDIIYLGKIKLEVLHTPGHPPESISFLLTDEGGGSSIPMGLFSGDFIFVGDVGRPDLLEK
AVNVEGSTKIGAKQMYQSIQFAATLPDYIQIWPGHGAGSPCGKALGSLPTTTLGYEKINNWAFNVKDETSFIETLTLNQP
APPHHFSQMKKINQFGMQMYQPYNVYPSSSNTQTAFDLRSKEAFHGGHMHGTINIPFNKTFINQIGWYLDYD

Sequences:

>Translated_312_residues
MFFKQFYEDNFSQASYLIGCQRTGEAMIIDPIRDLTKYLKVADKEGFTITKAAETHIHADFASGIRDVANKLNASIYVSD
EGKDEFNYKNMPKQTHFVKHQDIIYLGKIKLEVLHTPGHPPESISFLLTDEGGGSSIPMGLFSGDFIFVGDVGRPDLLEK
AVNVEGSTKIGAKQMYQSIQFAATLPDYIQIWPGHGAGSPCGKALGSLPTTTLGYEKINNWAFNVKDETSFIETLTLNQP
APPHHFSQMKKINQFGMQMYQPYNVYPSSSNTQTAFDLRSKEAFHGGHMHGTINIPFNKTFINQIGWYLDYD
>Mature_312_residues
MFFKQFYEDNFSQASYLIGCQRTGEAMIIDPIRDLTKYLKVADKEGFTITKAAETHIHADFASGIRDVANKLNASIYVSD
EGKDEFNYKNMPKQTHFVKHQDIIYLGKIKLEVLHTPGHPPESISFLLTDEGGGSSIPMGLFSGDFIFVGDVGRPDLLEK
AVNVEGSTKIGAKQMYQSIQFAATLPDYIQIWPGHGAGSPCGKALGSLPTTTLGYEKINNWAFNVKDETSFIETLTLNQP
APPHHFSQMKKINQFGMQMYQPYNVYPSSSNTQTAFDLRSKEAFHGGHMHGTINIPFNKTFINQIGWYLDYD

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI21703352, Length=188, Percent_Identity=30.8510638297872, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI116642887, Length=188, Percent_Identity=30.8510638297872, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1787158, Length=225, Percent_Identity=29.3333333333333, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538952, Length=242, Percent_Identity=25.2066115702479, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI221330176, Length=199, Percent_Identity=25.6281407035176, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR001763 [H]

Pfam domain/function: PF00753 Lactamase_B; PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 34958; Mature: 34958

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFKQFYEDNFSQASYLIGCQRTGEAMIIDPIRDLTKYLKVADKEGFTITKAAETHIHAD
CCCHHHHHCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCCEEEECHHHHHHHH
FASGIRDVANKLNASIYVSDEGKDEFNYKNMPKQTHFVKHQDIIYLGKIKLEVLHTPGHP
HHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHEECCCCEEEEEEEEEEEEECCCCC
PESISFLLTDEGGGSSIPMGLFSGDFIFVGDVGRPDLLEKAVNVEGSTKIGAKQMYQSIQ
CCCEEEEEEECCCCCCCCCEEECCCEEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHH
FAATLPDYIQIWPGHGAGSPCGKALGSLPTTTLGYEKINNWAFNVKDETSFIETLTLNQP
HHHCCCCCEEEECCCCCCCHHHHHHCCCCCCCCCHHHHCCCEEEECCCCCEEEEEECCCC
APPHHFSQMKKINQFGMQMYQPYNVYPSSSNTQTAFDLRSKEAFHGGHMHGTINIPFNKT
CCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCHH
FINQIGWYLDYD
HHHHCCCEEECC
>Mature Secondary Structure
MFFKQFYEDNFSQASYLIGCQRTGEAMIIDPIRDLTKYLKVADKEGFTITKAAETHIHAD
CCCHHHHHCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCCEEEECHHHHHHHH
FASGIRDVANKLNASIYVSDEGKDEFNYKNMPKQTHFVKHQDIIYLGKIKLEVLHTPGHP
HHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHEECCCCEEEEEEEEEEEEECCCCC
PESISFLLTDEGGGSSIPMGLFSGDFIFVGDVGRPDLLEKAVNVEGSTKIGAKQMYQSIQ
CCCEEEEEEECCCCCCCCCEEECCCEEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHH
FAATLPDYIQIWPGHGAGSPCGKALGSLPTTTLGYEKINNWAFNVKDETSFIETLTLNQP
HHHCCCCCEEEECCCCCCCHHHHHHCCCCCCCCCHHHHCCCEEEECCCCCEEEEEECCCC
APPHHFSQMKKINQFGMQMYQPYNVYPSSSNTQTAFDLRSKEAFHGGHMHGTINIPFNKT
CCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCHH
FINQIGWYLDYD
HHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]