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The map label for this gene is qor [H]

Identifier: 16127989

GI number: 16127989

Start: 4011404

End: 4012369

Strand: Direct

Name: qor [H]

Synonym: CC_3759

Alternate gene names: 16127989

Gene position: 4011404-4012369 (Clockwise)

Preceding gene: 16127988

Following gene: NA

Centisome position: 99.86

GC content: 68.32

Gene sequence:

>966_bases
ATGCTGGCGGTCCAAGCGGTCAGGACCGGCGGCCCCGAGGTTCTGGAGGTCGTCGATCTTCCCCTACCCTCGCCGGGTCC
GGGTCAGATCCTCGTCCGCCACCAGGCGGTGGGTCTGAACTATATCGACACCTATCACCGATCCGGCCTGTATCCCGTGA
AAACACCGCTGGTGATCGGGCTGGAAGCGGCCGGCGTGGTCGAGTCCGTCGGCGAGGCGGTCACACGCTTCAAGGTCGGT
GACCGGGTAGCCTATAACGGAACCATGGGCGCCTATGCCCAAGCCGCCGTCGTGCCAGCGGAGCGCGCGGTGCTTGTTCC
CGACGGTGTCAGCCTGGAGGTCGCGGCCGCCGCTCTGTTGAAGGGCATGACCGCGGAGTTTCTGGTGCGTCGATGTTTCC
ACGTGAAACAAGGCGACTGGGTTCTGGTCCATGCGGCGGCCGGCGGCGTCGGTCAGATCCTGGTCCAATGGTGCAAGGCC
CTTGGCGCCACGGTGGTGGCCACAGTCGGATCGACGGCGAAGGCCACGATCGCCCGCGATCTCGGCGCCGACCATGTCAT
CGACTACAGCCACGAGGATGTCGCGGCTCGGGTCGCCGAACTCACGGGCGGCCGGGGCGTCGCGGTCGTCTATGACGGTG
TCGGCAAGGATACCTGGGAGGCCAGTCTCGCCAGCCTCGCCCGGCGCGGCATGCTGGTGACGTTCGGCAACGCCTCGGGT
CCGGCGCCCGCCTTCCCGCCGCTGGCGCTGGCGCCCAAGTCCGCCTTCGTCACCCGGCCCAAGCTGTTCGACTACATCGT
CACGACCGAGGAACTGGACGAAAGCGCCCAGGCGCTGTTCGCGGTGATCGCCTCGGGCGCCATCAAGATCGACATCGGCC
AGACCTTCCCCCTCGCCGAGGCCCGCGCGGCGCACGAGGCCCTGGAAGGCCGTCGCACCACCGGCGCCACCCTGCTCCTT
CCGTAG

Upstream 100 bases:

>100_bases
ACCACGCCTTCGCCCGCGAGGGTGGCGCGCACTACGACGCGGCCGACGCCGCCAAGGCCAACGGCCGCAGCCTGACCTTC
TTCCAGCAGGCCCTGGCCTG

Downstream 100 bases:

>100_bases
GGCCTGACCGGGTACGACCGAACAAAAAAGGCGCCGGGTAGCACCGGCGCCTTTCTCGTTTCGGTATGAGTCTGTTTGGA
CTCAGGTGTTCATCGACTGG

Product: quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MLAVQAVRTGGPEVLEVVDLPLPSPGPGQILVRHQAVGLNYIDTYHRSGLYPVKTPLVIGLEAAGVVESVGEAVTRFKVG
DRVAYNGTMGAYAQAAVVPAERAVLVPDGVSLEVAAAALLKGMTAEFLVRRCFHVKQGDWVLVHAAAGGVGQILVQWCKA
LGATVVATVGSTAKATIARDLGADHVIDYSHEDVAARVAELTGGRGVAVVYDGVGKDTWEASLASLARRGMLVTFGNASG
PAPAFPPLALAPKSAFVTRPKLFDYIVTTEELDESAQALFAVIASGAIKIDIGQTFPLAEARAAHEALEGRRTTGATLLL
P

Sequences:

>Translated_321_residues
MLAVQAVRTGGPEVLEVVDLPLPSPGPGQILVRHQAVGLNYIDTYHRSGLYPVKTPLVIGLEAAGVVESVGEAVTRFKVG
DRVAYNGTMGAYAQAAVVPAERAVLVPDGVSLEVAAAALLKGMTAEFLVRRCFHVKQGDWVLVHAAAGGVGQILVQWCKA
LGATVVATVGSTAKATIARDLGADHVIDYSHEDVAARVAELTGGRGVAVVYDGVGKDTWEASLASLARRGMLVTFGNASG
PAPAFPPLALAPKSAFVTRPKLFDYIVTTEELDESAQALFAVIASGAIKIDIGQTFPLAEARAAHEALEGRRTTGATLLL
P
>Mature_321_residues
MLAVQAVRTGGPEVLEVVDLPLPSPGPGQILVRHQAVGLNYIDTYHRSGLYPVKTPLVIGLEAAGVVESVGEAVTRFKVG
DRVAYNGTMGAYAQAAVVPAERAVLVPDGVSLEVAAAALLKGMTAEFLVRRCFHVKQGDWVLVHAAAGGVGQILVQWCKA
LGATVVATVGSTAKATIARDLGADHVIDYSHEDVAARVAELTGGRGVAVVYDGVGKDTWEASLASLARRGMLVTFGNASG
PAPAFPPLALAPKSAFVTRPKLFDYIVTTEELDESAQALFAVIASGAIKIDIGQTFPLAEARAAHEALEGRRTTGATLLL
P

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=338, Percent_Identity=31.0650887573964, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI22538444, Length=338, Percent_Identity=31.0650887573964, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI194239674, Length=325, Percent_Identity=31.3846153846154, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI13236495, Length=325, Percent_Identity=31.3846153846154, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=31.5112540192926, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI24308257, Length=241, Percent_Identity=32.3651452282158, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI28557745, Length=225, Percent_Identity=37.7777777777778, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI194239676, Length=325, Percent_Identity=30.4615384615385, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI156627571, Length=215, Percent_Identity=32.5581395348837, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI197927207, Length=187, Percent_Identity=28.8770053475936, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1790485, Length=319, Percent_Identity=48.2758620689655, Blast_Score=293, Evalue=9e-81,
Organism=Escherichia coli, GI87081918, Length=211, Percent_Identity=27.0142180094787, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=242, Percent_Identity=35.5371900826446, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17556000, Length=310, Percent_Identity=27.0967741935484, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17536829, Length=279, Percent_Identity=29.7491039426523, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71988145, Length=257, Percent_Identity=27.6264591439689, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17562584, Length=260, Percent_Identity=28.4615384615385, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=316, Percent_Identity=41.1392405063291, Blast_Score=247, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6324486, Length=296, Percent_Identity=28.3783783783784, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323961, Length=296, Percent_Identity=27.3648648648649, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6319621, Length=253, Percent_Identity=29.2490118577075, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319955, Length=260, Percent_Identity=30, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI45550423, Length=316, Percent_Identity=25.6329113924051, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33364; Mature: 33364

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAVQAVRTGGPEVLEVVDLPLPSPGPGQILVRHQAVGLNYIDTYHRSGLYPVKTPLVIG
CCEEEEECCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCEEEE
LEAAGVVESVGEAVTRFKVGDRVAYNGTMGAYAQAAVVPAERAVLVPDGVSLEVAAAALL
ECHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHEEECCCCCEEECCCCCCHHHHHHHHH
KGMTAEFLVRRCFHVKQGDWVLVHAAAGGVGQILVQWCKALGATVVATVGSTAKATIARD
HCCHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHH
LGADHVIDYSHEDVAARVAELTGGRGVAVVYDGVGKDTWEASLASLARRGMLVTFGNASG
CCCCCEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEEEECCCCC
PAPAFPPLALAPKSAFVTRPKLFDYIVTTEELDESAQALFAVIASGAIKIDIGQTFPLAE
CCCCCCCCEECCCHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHH
ARAAHEALEGRRTTGATLLLP
HHHHHHHHCCCCCCCEEEECC
>Mature Secondary Structure
MLAVQAVRTGGPEVLEVVDLPLPSPGPGQILVRHQAVGLNYIDTYHRSGLYPVKTPLVIG
CCEEEEECCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCEEEE
LEAAGVVESVGEAVTRFKVGDRVAYNGTMGAYAQAAVVPAERAVLVPDGVSLEVAAAALL
ECHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHEEECCCCCEEECCCCCCHHHHHHHHH
KGMTAEFLVRRCFHVKQGDWVLVHAAAGGVGQILVQWCKALGATVVATVGSTAKATIARD
HCCHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHH
LGADHVIDYSHEDVAARVAELTGGRGVAVVYDGVGKDTWEASLASLARRGMLVTFGNASG
CCCCCEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEEEECCCCC
PAPAFPPLALAPKSAFVTRPKLFDYIVTTEELDESAQALFAVIASGAIKIDIGQTFPLAE
CCCCCCCCEECCCHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHH
ARAAHEALEGRRTTGATLLLP
HHHHHHHHCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]