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The map label for this gene is ftsK

Identifier: 16127934

GI number: 16127934

Start: 3957904

End: 3960363

Strand: Direct

Name: ftsK

Synonym: CC_3704

Alternate gene names: 16127934

Gene position: 3957904-3960363 (Clockwise)

Preceding gene: 16127933

Following gene: 16127935

Centisome position: 98.53

GC content: 69.67

Gene sequence:

>2460_bases
ATGGCGCGAGCCGCGCGGCGATCCACGACGGAGCTCCTTTGGGATGCGATCCGTTATGGCTGGGCCCAGCCCTGGACGGC
CCGGTTCCGGGGCGGGATCGTCACCGTCGTCGGGGCGGTGCTGCTGCTCGCTATCGCCACCTATAACGCCACCGATCCCA
GCTTCAACGCCGTGACGGGCGAGCCGGCTAGCAATGCGCTGGGCGGCCTGGGCGCGGCGATTTCCGATATTCTGATGCAG
TCGCTGGGCCTGTCGGCCTGGGGCATTGCGCTGCTGATGCTGGTGTTCGGCGTCACCCGCGTGGCCCAGGCCGACCCCGA
CGCCGACCGCAAGGACCTGCGCCAGCGGGCGCTGGTCGGGGCGCTGGGCCTCTTGGCGCTGTCGGCCGTGCTGGCCGCGC
CGCCGCCACCCGCCATCTGGCAGCTAGAAAAGGGTCTGGGCGGCTTCTGGGGCGACTCCCTGCTGCACATGGTCGCCGCT
GTCCTCAGCTTCGCCCACATCCCCGGCGCGACCATCATCGCCGCCATCCTGTTCGGGATCGCCGCCATCGCGGCGCTCGG
CTTCGCCATCGGCGTGCGTGAGGTCGACCCCGACGCCATCCACGCCGCCGTCAGCAACGCCCTGCAACCCCGCGCGCGCC
CTGAGCCGGAACCGGAACCCGCGCCCGCAGCCAAGCCCGTCCGCGCCAGGCGCGAGAAGGCCGAACCCGCGGCCCCGCGC
GCCGGTCGCCTGCCCCCCCTGGAGGCCGACGAGGACGAAACCCCGATCGCGGCCTCGCAGCCGGCCGCTGCGCAGCGCGC
CTATACCCCGCCGCCGGCGGTCCAGGACGACGAGGACGACTTCGAGGACAGCCTGGACGCCCGGCCCATGGCCATCGCCA
AGCCCAAGACGCCTGTGAAGGAGTCCGGCCGTGAGGCGCGCGAGCAGCAGAAGGCCTTCGACTTCGAGGAAGACGCCGGC
TTCCAGCTGCCCGAACTGGCCATGCTGGCCAAGTCCAAGCCGCGCTCGTCCGAGGTGGACGCCGCGGCCCTGCGCCAGAA
CGCCCGCCTGCTGGAAAGCGTGCTGGCCGAGTTCGGCGTCAAGGGCCAGATCGACCAGATCCGCCCCGGCCCGGTGGTCA
CCATGTACGAGCTGGTGCCCGCCCCGGGCGTCAAGACCGCCCGCGTCGTTGCGCTCGCCGATGACATCGCCCGCTCGATG
AGCGTGATCTCGTGCCGCGTGGCCGTGGCCCAGGGCCGCAACGCCATCGGCATCGAAATGCCCAACCAGCGGCGCGAGAC
CGTCTATCTGCGCGACCTGCTGTCCAGCGCCGACTATGAGAAGGCCAGCCAGATCCTGCCCATGGCGCTGGGCGAGACCA
TCGGCGGCGAGCCGTATATCGCCGACCTCGCCAAGATGCCCCACTTGCTGATCGCCGGCACCACCGGCTCGGGCAAGTCG
GTCGGCGTCAACGCCATGATCCTGTCGATCCTGTACAAGCTGCCGCCCGAGAAGTGCCGCTTCATCATGGTCGATCCCAA
GATGCTGGAACTGAGCGTCTATGACGGCATCCCGCACCTTCTGGCCCCCGTCGTGACCGATCCGAAGAAGGCCGTCGTGG
CCCTGAAGTGGACCGTCCGCGAGATGGAGGACCGCTATCGGCGGATGTCCAAGATCGGCGTGCGCAACATCGGCGGCTAC
AACGAGAAGGCCAACGAGGCGGCCGCCAAGGGCGAGCACTTCGAGCGCACGGTCCAGACGGGCTTCGACGACGCCGGGCG
TCCGATCTATGAGACCGAGCAGATCCGCCCCGAGCCCATGCCCTATCTCGTCGTGGTCATCGACGAGGTGGCCGACCTGA
TGATGGTGGCCGGCAAGGATATCGAAGGCGCCGTGCAGCGCCTGGCCCAGATGGCCCGCGCCGCCGGCATCCACCTGATC
ATGGCCACCCAGCGCCCGTCGGTCGACGTCATCACCGGCACGATCAAGGCCAACTTCCCGACCCGGATCAGCTTCCAGGT
CACTTCGAAGATCGACGCCCGCACCATTCTGGGCGAGCAGGGCGCCGAGCAGCTGCTGGGCCAGGGCGACATGCTCTACA
TGGCCGGCGGCGGTCGCATCACCCGCCTGCACGGCCCGTTCGTGTCGGACGGTGAAGTCGAGGCCGTGGCCAGGTTCCTG
CGCGACCAGGGCATTCCGCAGTACCTCGACGAGGTCACCGCCGGCGGCGACGAGGAGCAGGAAGAGGCCATCGAAGGCGC
ATTCTCAGGCGAAGGCGGCGCCAACGACCTCTACGACCACGCCGTGGCCGTGGTCACCCGCGACCGCAAGGCCTCGACCA
GCTACATCCAGCGCCGCCTGCAGATCGGCTACAACCGCGCCGCCTCGCTGATGGAACGGATGGAGAAGGAGGGCGTCGTC
GGCGCCGCCAATCACGCCGGCAAGCGGGAGATTTTGGCCCCGCCGACGCCGCCGCTCTAG

Upstream 100 bases:

>100_bases
GGACGTCGTAAACAGCCCTTAACGCTCTTCAGGCACAACATCGCGGTTCGACCCGTCTTGCGCGGGTCCAAAGAGACGAC
GGTTGAGTTCGGAGACTTTC

Downstream 100 bases:

>100_bases
GCGGCCTCGAGCGATGCTGCGGCGTTTCGGACGCCCCCAACCTGAACGCGGCTTCATCGCGCCGCCGGAAAATGGCCTTG
CGACGGCCTTCGCGGCGGCC

Product: cell division protein FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 819; Mature: 818

Protein sequence:

>819_residues
MARAARRSTTELLWDAIRYGWAQPWTARFRGGIVTVVGAVLLLAIATYNATDPSFNAVTGEPASNALGGLGAAISDILMQ
SLGLSAWGIALLMLVFGVTRVAQADPDADRKDLRQRALVGALGLLALSAVLAAPPPPAIWQLEKGLGGFWGDSLLHMVAA
VLSFAHIPGATIIAAILFGIAAIAALGFAIGVREVDPDAIHAAVSNALQPRARPEPEPEPAPAAKPVRARREKAEPAAPR
AGRLPPLEADEDETPIAASQPAAAQRAYTPPPAVQDDEDDFEDSLDARPMAIAKPKTPVKESGREAREQQKAFDFEEDAG
FQLPELAMLAKSKPRSSEVDAAALRQNARLLESVLAEFGVKGQIDQIRPGPVVTMYELVPAPGVKTARVVALADDIARSM
SVISCRVAVAQGRNAIGIEMPNQRRETVYLRDLLSSADYEKASQILPMALGETIGGEPYIADLAKMPHLLIAGTTGSGKS
VGVNAMILSILYKLPPEKCRFIMVDPKMLELSVYDGIPHLLAPVVTDPKKAVVALKWTVREMEDRYRRMSKIGVRNIGGY
NEKANEAAAKGEHFERTVQTGFDDAGRPIYETEQIRPEPMPYLVVVIDEVADLMMVAGKDIEGAVQRLAQMARAAGIHLI
MATQRPSVDVITGTIKANFPTRISFQVTSKIDARTILGEQGAEQLLGQGDMLYMAGGGRITRLHGPFVSDGEVEAVARFL
RDQGIPQYLDEVTAGGDEEQEEAIEGAFSGEGGANDLYDHAVAVVTRDRKASTSYIQRRLQIGYNRAASLMERMEKEGVV
GAANHAGKREILAPPTPPL

Sequences:

>Translated_819_residues
MARAARRSTTELLWDAIRYGWAQPWTARFRGGIVTVVGAVLLLAIATYNATDPSFNAVTGEPASNALGGLGAAISDILMQ
SLGLSAWGIALLMLVFGVTRVAQADPDADRKDLRQRALVGALGLLALSAVLAAPPPPAIWQLEKGLGGFWGDSLLHMVAA
VLSFAHIPGATIIAAILFGIAAIAALGFAIGVREVDPDAIHAAVSNALQPRARPEPEPEPAPAAKPVRARREKAEPAAPR
AGRLPPLEADEDETPIAASQPAAAQRAYTPPPAVQDDEDDFEDSLDARPMAIAKPKTPVKESGREAREQQKAFDFEEDAG
FQLPELAMLAKSKPRSSEVDAAALRQNARLLESVLAEFGVKGQIDQIRPGPVVTMYELVPAPGVKTARVVALADDIARSM
SVISCRVAVAQGRNAIGIEMPNQRRETVYLRDLLSSADYEKASQILPMALGETIGGEPYIADLAKMPHLLIAGTTGSGKS
VGVNAMILSILYKLPPEKCRFIMVDPKMLELSVYDGIPHLLAPVVTDPKKAVVALKWTVREMEDRYRRMSKIGVRNIGGY
NEKANEAAAKGEHFERTVQTGFDDAGRPIYETEQIRPEPMPYLVVVIDEVADLMMVAGKDIEGAVQRLAQMARAAGIHLI
MATQRPSVDVITGTIKANFPTRISFQVTSKIDARTILGEQGAEQLLGQGDMLYMAGGGRITRLHGPFVSDGEVEAVARFL
RDQGIPQYLDEVTAGGDEEQEEAIEGAFSGEGGANDLYDHAVAVVTRDRKASTSYIQRRLQIGYNRAASLMERMEKEGVV
GAANHAGKREILAPPTPPL
>Mature_818_residues
ARAARRSTTELLWDAIRYGWAQPWTARFRGGIVTVVGAVLLLAIATYNATDPSFNAVTGEPASNALGGLGAAISDILMQS
LGLSAWGIALLMLVFGVTRVAQADPDADRKDLRQRALVGALGLLALSAVLAAPPPPAIWQLEKGLGGFWGDSLLHMVAAV
LSFAHIPGATIIAAILFGIAAIAALGFAIGVREVDPDAIHAAVSNALQPRARPEPEPEPAPAAKPVRARREKAEPAAPRA
GRLPPLEADEDETPIAASQPAAAQRAYTPPPAVQDDEDDFEDSLDARPMAIAKPKTPVKESGREAREQQKAFDFEEDAGF
QLPELAMLAKSKPRSSEVDAAALRQNARLLESVLAEFGVKGQIDQIRPGPVVTMYELVPAPGVKTARVVALADDIARSMS
VISCRVAVAQGRNAIGIEMPNQRRETVYLRDLLSSADYEKASQILPMALGETIGGEPYIADLAKMPHLLIAGTTGSGKSV
GVNAMILSILYKLPPEKCRFIMVDPKMLELSVYDGIPHLLAPVVTDPKKAVVALKWTVREMEDRYRRMSKIGVRNIGGYN
EKANEAAAKGEHFERTVQTGFDDAGRPIYETEQIRPEPMPYLVVVIDEVADLMMVAGKDIEGAVQRLAQMARAAGIHLIM
ATQRPSVDVITGTIKANFPTRISFQVTSKIDARTILGEQGAEQLLGQGDMLYMAGGGRITRLHGPFVSDGEVEAVARFLR
DQGIPQYLDEVTAGGDEEQEEAIEGAFSGEGGANDLYDHAVAVVTRDRKASTSYIQRRLQIGYNRAASLMERMEKEGVVG
AANHAGKREILAPPTPPL

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain

Homologues:

Organism=Escherichia coli, GI1787117, Length=497, Percent_Identity=53.5211267605634, Blast_Score=500, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSK_CAUCR (Q9A262)

Other databases:

- EMBL:   AE005673
- PIR:   F87708
- RefSeq:   NP_422498.1
- ProteinModelPortal:   Q9A262
- SMR:   Q9A262
- GeneID:   943473
- GenomeReviews:   AE005673_GR
- KEGG:   ccr:CC_3704
- NMPDR:   fig|190650.1.peg.3678
- TIGR:   CC_3704
- HOGENOM:   HBG662140
- OMA:   GEHFERT
- ProtClustDB:   CLSK891658
- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- SMART:   SM00382
- SMART:   SM00843

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE

EC number: NA

Molecular weight: Translated: 87843; Mature: 87712

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12cf1fc0)-; HASH(0x12220098)-; HASH(0x11d2b484)-; HASH(0x12ae8034)-; HASH(0x12e84af4)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARAARRSTTELLWDAIRYGWAQPWTARFRGGIVTVVGAVLLLAIATYNATDPSFNAVTG
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
EPASNALGGLGAAISDILMQSLGLSAWGIALLMLVFGVTRVAQADPDADRKDLRQRALVG
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ALGLLALSAVLAAPPPPAIWQLEKGLGGFWGDSLLHMVAAVLSFAHIPGATIIAAILFGI
HHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AAIAALGFAIGVREVDPDAIHAAVSNALQPRARPEPEPEPAPAAKPVRARREKAEPAAPR
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCC
AGRLPPLEADEDETPIAASQPAAAQRAYTPPPAVQDDEDDFEDSLDARPMAIAKPKTPVK
CCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHCCCCCEEECCCCCCHH
ESGREAREQQKAFDFEEDAGFQLPELAMLAKSKPRSSEVDAAALRQNARLLESVLAEFGV
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
KGQIDQIRPGPVVTMYELVPAPGVKTARVVALADDIARSMSVISCRVAVAQGRNAIGIEM
CCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
PNQRRETVYLRDLLSSADYEKASQILPMALGETIGGEPYIADLAKMPHLLIAGTTGSGKS
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEECCCCCCC
VGVNAMILSILYKLPPEKCRFIMVDPKMLELSVYDGIPHLLAPVVTDPKKAVVALKWTVR
CCHHHHHHHHHHHCCCCCCCEEEECCCEEEEEHHCCCHHHHHHHCCCCCCEEEEHHHHHH
EMEDRYRRMSKIGVRNIGGYNEKANEAAAKGEHFERTVQTGFDDAGRPIYETEQIRPEPM
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHCCCCCCC
PYLVVVIDEVADLMMVAGKDIEGAVQRLAQMARAAGIHLIMATQRPSVDVITGTIKANFP
CEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEEECCC
TRISFQVTSKIDARTILGEQGAEQLLGQGDMLYMAGGGRITRLHGPFVSDGEVEAVARFL
CEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHH
RDQGIPQYLDEVTAGGDEEQEEAIEGAFSGEGGANDLYDHAVAVVTRDRKASTSYIQRRL
HHCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHEEECCCCHHHHHHHHHH
QIGYNRAASLMERMEKEGVVGAANHAGKREILAPPTPPL
HHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCH
>Mature Secondary Structure 
ARAARRSTTELLWDAIRYGWAQPWTARFRGGIVTVVGAVLLLAIATYNATDPSFNAVTG
CCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
EPASNALGGLGAAISDILMQSLGLSAWGIALLMLVFGVTRVAQADPDADRKDLRQRALVG
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ALGLLALSAVLAAPPPPAIWQLEKGLGGFWGDSLLHMVAAVLSFAHIPGATIIAAILFGI
HHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AAIAALGFAIGVREVDPDAIHAAVSNALQPRARPEPEPEPAPAAKPVRARREKAEPAAPR
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCC
AGRLPPLEADEDETPIAASQPAAAQRAYTPPPAVQDDEDDFEDSLDARPMAIAKPKTPVK
CCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHCCCCCEEECCCCCCHH
ESGREAREQQKAFDFEEDAGFQLPELAMLAKSKPRSSEVDAAALRQNARLLESVLAEFGV
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
KGQIDQIRPGPVVTMYELVPAPGVKTARVVALADDIARSMSVISCRVAVAQGRNAIGIEM
CCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
PNQRRETVYLRDLLSSADYEKASQILPMALGETIGGEPYIADLAKMPHLLIAGTTGSGKS
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEECCCCCCC
VGVNAMILSILYKLPPEKCRFIMVDPKMLELSVYDGIPHLLAPVVTDPKKAVVALKWTVR
CCHHHHHHHHHHHCCCCCCCEEEECCCEEEEEHHCCCHHHHHHHCCCCCCEEEEHHHHHH
EMEDRYRRMSKIGVRNIGGYNEKANEAAAKGEHFERTVQTGFDDAGRPIYETEQIRPEPM
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHCCCCCCC
PYLVVVIDEVADLMMVAGKDIEGAVQRLAQMARAAGIHLIMATQRPSVDVITGTIKANFP
CEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEEECCC
TRISFQVTSKIDARTILGEQGAEQLLGQGDMLYMAGGGRITRLHGPFVSDGEVEAVARFL
CEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHH
RDQGIPQYLDEVTAGGDEEQEEAIEGAFSGEGGANDLYDHAVAVVTRDRKASTSYIQRRL
HHCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHEEECCCCHHHHHHHHHH
QIGYNRAASLMERMEKEGVVGAANHAGKREILAPPTPPL
HHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647