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The map label for this gene is ald [H]

Identifier: 16127804

GI number: 16127804

Start: 3828903

End: 3830015

Strand: Direct

Name: ald [H]

Synonym: CC_3574

Alternate gene names: 16127804

Gene position: 3828903-3830015 (Clockwise)

Preceding gene: 16127799

Following gene: 16127807

Centisome position: 95.32

GC content: 69.99

Gene sequence:

>1113_bases
ATGCGCGTTGGCGTCCCTTCCGAGATCAAACCGGGCGAACACCGGGTCGGACTTACCCCCACCGCCGTCCGTGAATATGT
CGGCCACGGCCACACCGTCATCGTCCAGTCGGGCGCGGGCCTCGGCGCCGGCTATGCCGACGACGTCTACGTCAAGGCGG
GCGCGAGCATCGTCGCCGACGCCGACGCGGTGTTCGCCGGCGCGGACATGATCGTGAAGGTCAAGGAGCCGCAGAAGGTC
GAGTGGGAAAAGCTGGAGCCGCGCCACATCCTCTTCACCTATCTGCACCTGGCGCCCGATCCGGCCCAGACCGAAGGCCT
GCTCAAGAGCGGCTGCGCGGCCATCGCCTATGAAACCGTGACCGACGCCAAGGGCGGCCTGCCGCTGCTGGCCCCGATGT
CGGAAGTGGCCGGCCGCATCGCCGTGTTCTCGGCGGCCGAGACGTTGCTCAAGCACAATGGCGGCATGGGCCTGCTGCTC
AGCGGCGTGCCCGGCGTGCCCCCGGCCCGCGTCGCCGTGCTGGGCGGCGGCGTGGTCGGCAGCAACGCCGCGCGCATGGC
CGCGGGCCTGGGCGCCGAGGTCGTGGTGCTGGAACGCTCGATCCCGCGCATGCGCGAACTGGACGATCTCTACCAGGGCC
GGATCCTGACCCGCTACTCGACCTTCGGGGCGGTGGAAGAAGAGATCCTCAAGGCCGACGTCGTGATCGGCGCGGTGCTG
ACCGCCGGTGCGGCCGCGCCCAAGCTGGTGCGTCGCGAGCACCTCAAGCAGATGAAGCCGGGCTCGGTGCTGGTCGACGT
CTCGATCGACCAGGGCGGCTGCTTTGAGACCAGCAAGCCGACCACCCACGCCCAGCCGACCTACACGGTCGACGGCGTCG
TCCACTACTGCGTGGCCAACATGCCGGGCGCGGCGCCGCGCACCTCGTCCGAAGCGCTGGGCAACGCCACCCTGCCCTTC
GGCCTGGCCCTGGCCGACAAGGGTCTCGACGCCCTGAAGGCCAACGCCCACCTGGCCCGGGGCCTCAACGTCCTGAACGG
CGAACTGACCCACCCGGCCGTGGCCGAGGCTTTGGGCAAGACCTCGATCGATCCCTACGGCGCCTGGAAGTAG

Upstream 100 bases:

>100_bases
GGATTCCTGCATCAACCGATGTCTCGAGGCCGAAAACGCCATGAAAACTGCAAGGAAAGAGGCGCATGATCGATCTCAAA
GCGCTTTTGGAGGAAACATC

Downstream 100 bases:

>100_bases
GGGCCTCCGATCATCGGACAGAAGAAGGGCGCCGTGCGGGTTTCGCGCGGCGCCCTTTGAGTTTTTGGGAGAGGAACACA
GACGCTTACGAAAACTCAGG

Product: alanine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MRVGVPSEIKPGEHRVGLTPTAVREYVGHGHTVIVQSGAGLGAGYADDVYVKAGASIVADADAVFAGADMIVKVKEPQKV
EWEKLEPRHILFTYLHLAPDPAQTEGLLKSGCAAIAYETVTDAKGGLPLLAPMSEVAGRIAVFSAAETLLKHNGGMGLLL
SGVPGVPPARVAVLGGGVVGSNAARMAAGLGAEVVVLERSIPRMRELDDLYQGRILTRYSTFGAVEEEILKADVVIGAVL
TAGAAAPKLVRREHLKQMKPGSVLVDVSIDQGGCFETSKPTTHAQPTYTVDGVVHYCVANMPGAAPRTSSEALGNATLPF
GLALADKGLDALKANAHLARGLNVLNGELTHPAVAEALGKTSIDPYGAWK

Sequences:

>Translated_370_residues
MRVGVPSEIKPGEHRVGLTPTAVREYVGHGHTVIVQSGAGLGAGYADDVYVKAGASIVADADAVFAGADMIVKVKEPQKV
EWEKLEPRHILFTYLHLAPDPAQTEGLLKSGCAAIAYETVTDAKGGLPLLAPMSEVAGRIAVFSAAETLLKHNGGMGLLL
SGVPGVPPARVAVLGGGVVGSNAARMAAGLGAEVVVLERSIPRMRELDDLYQGRILTRYSTFGAVEEEILKADVVIGAVL
TAGAAAPKLVRREHLKQMKPGSVLVDVSIDQGGCFETSKPTTHAQPTYTVDGVVHYCVANMPGAAPRTSSEALGNATLPF
GLALADKGLDALKANAHLARGLNVLNGELTHPAVAEALGKTSIDPYGAWK
>Mature_370_residues
MRVGVPSEIKPGEHRVGLTPTAVREYVGHGHTVIVQSGAGLGAGYADDVYVKAGASIVADADAVFAGADMIVKVKEPQKV
EWEKLEPRHILFTYLHLAPDPAQTEGLLKSGCAAIAYETVTDAKGGLPLLAPMSEVAGRIAVFSAAETLLKHNGGMGLLL
SGVPGVPPARVAVLGGGVVGSNAARMAAGLGAEVVVLERSIPRMRELDDLYQGRILTRYSTFGAVEEEILKADVVIGAVL
TAGAAAPKLVRREHLKQMKPGSVLVDVSIDQGGCFETSKPTTHAQPTYTVDGVVHYCVANMPGAAPRTSSEALGNATLPF
GLALADKGLDALKANAHLARGLNVLNGELTHPAVAEALGKTSIDPYGAWK

Specific function: May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=343, Percent_Identity=28.2798833819242, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI122939153, Length=343, Percent_Identity=28.2798833819242, Blast_Score=116, Evalue=4e-26,
Organism=Escherichia coli, GI1787887, Length=380, Percent_Identity=30.5263157894737, Blast_Score=123, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17550456, Length=372, Percent_Identity=29.5698924731183, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 38395; Mature: 38395

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVGVPSEIKPGEHRVGLTPTAVREYVGHGHTVIVQSGAGLGAGYADDVYVKAGASIVAD
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEECCCCEEEC
ADAVFAGADMIVKVKEPQKVEWEKLEPRHILFTYLHLAPDPAQTEGLLKSGCAAIAYETV
CCCEEECCCEEEEECCCCCCCHHHCCCCEEEEEEEEECCCCHHHHHHHHHCCHHEEEHHH
TDAKGGLPLLAPMSEVAGRIAVFSAAETLLKHNGGMGLLLSGVPGVPPARVAVLGGGVVG
HCCCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCEEC
SNAARMAAGLGAEVVVLERSIPRMRELDDLYQGRILTRYSTFGAVEEEILKADVVIGAVL
CCHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
TAGAAAPKLVRREHLKQMKPGSVLVDVSIDQGGCFETSKPTTHAQPTYTVDGVVHYCVAN
HCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHC
MPGAAPRTSSEALGNATLPFGLALADKGLDALKANAHLARGLNVLNGELTHPAVAEALGK
CCCCCCCCCHHHCCCCCCCCEEHHHHCCHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHCC
TSIDPYGAWK
CCCCCCCCCC
>Mature Secondary Structure
MRVGVPSEIKPGEHRVGLTPTAVREYVGHGHTVIVQSGAGLGAGYADDVYVKAGASIVAD
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEECCCCEEEC
ADAVFAGADMIVKVKEPQKVEWEKLEPRHILFTYLHLAPDPAQTEGLLKSGCAAIAYETV
CCCEEECCCEEEEECCCCCCCHHHCCCCEEEEEEEEECCCCHHHHHHHHHCCHHEEEHHH
TDAKGGLPLLAPMSEVAGRIAVFSAAETLLKHNGGMGLLLSGVPGVPPARVAVLGGGVVG
HCCCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCEEC
SNAARMAAGLGAEVVVLERSIPRMRELDDLYQGRILTRYSTFGAVEEEILKADVVIGAVL
CCHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
TAGAAAPKLVRREHLKQMKPGSVLVDVSIDQGGCFETSKPTTHAQPTYTVDGVVHYCVAN
HCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHC
MPGAAPRTSSEALGNATLPFGLALADKGLDALKANAHLARGLNVLNGELTHPAVAEALGK
CCCCCCCCCHHHCCCCCCCCEEHHHHCCHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHCC
TSIDPYGAWK
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA