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The map label for this gene is can [H]

Identifier: 16127799

GI number: 16127799

Start: 3819321

End: 3819989

Strand: Direct

Name: can [H]

Synonym: CC_3569

Alternate gene names: 16127799

Gene position: 3819321-3819989 (Clockwise)

Preceding gene: 16127798

Following gene: 16127804

Centisome position: 95.08

GC content: 65.17

Gene sequence:

>669_bases
ATGCTTGAAGACCTGAAAGCCAAGAACGCCGCCTGGTCGAAGAGCAAGACGGCGGAAGATCCGGATTTCTTTACACGCCT
GGCCAAGCAGCAAAGCCCGGAATATCTGTGGATCGGCTGCAGCGACAGCCGCGTGCCGGCCAACGAGATCGTCGGGCTCG
ACCCCGGCGAGCTCTTCGTGCACCGCAATGTGGCCAACCTCGCCCCGCCGCAGGACGCCAACTATTTGAGCGTGCTGCAG
TTCGCGGTCGACGTCTTGAAGGTCAAGCACATCATGGTCGTGGGCCACTATGGCTGCGGCGGGGTGGCGGCGGCGATCGA
CGGCAAGCGCCGGGGCCTGGTCGATCACTGGCTCCACCCGATCCGCGAGGTCTACGCCGAACACCGCCCAGAGCTCGAGG
CGATCCCGGAAAAGCGCGAGATGATCGACCGCCTGACCGAGCTGAACGTCGCCCGCCAGGTGCGCAACGTCGCCGCCGAC
GTCTTCGTCCAGGACGCCTGGGCGCGCGGCCAGTCACTGGCCGTGCACGGCTGGGTCTATTCGCTGGCCAATGGCCTGGT
GAACGACCTCAATGTCGGCATTGCCAGCCTCGAGGATTATGAGCGCACGGTGGCGGAGACGGTGGTTCCGGATCGTCCGT
TCTGGAAGCGGGGCCAGGCGGAAGGATAG

Upstream 100 bases:

>100_bases
CGACCTGTCGCCGTTTCCGGCCCTGGAAGCCGCCGCCGCGCATGCCCGGGCGCATCCGGCGATCGCCGCAGCTCACCCTG
ACCACCATCCGGAACGCTAG

Downstream 100 bases:

>100_bases
AGGGCTCTAAATCTCTGATTTATAGCCTTTTTATCTGGTTTAGAGACTGGGGTGGAACACCAACGAACTTCACCGGACTA
TTCTCCCTTGATCCGCACCT

Product: carbonic anhydrase family protein

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MLEDLKAKNAAWSKSKTAEDPDFFTRLAKQQSPEYLWIGCSDSRVPANEIVGLDPGELFVHRNVANLAPPQDANYLSVLQ
FAVDVLKVKHIMVVGHYGCGGVAAAIDGKRRGLVDHWLHPIREVYAEHRPELEAIPEKREMIDRLTELNVARQVRNVAAD
VFVQDAWARGQSLAVHGWVYSLANGLVNDLNVGIASLEDYERTVAETVVPDRPFWKRGQAEG

Sequences:

>Translated_222_residues
MLEDLKAKNAAWSKSKTAEDPDFFTRLAKQQSPEYLWIGCSDSRVPANEIVGLDPGELFVHRNVANLAPPQDANYLSVLQ
FAVDVLKVKHIMVVGHYGCGGVAAAIDGKRRGLVDHWLHPIREVYAEHRPELEAIPEKREMIDRLTELNVARQVRNVAAD
VFVQDAWARGQSLAVHGWVYSLANGLVNDLNVGIASLEDYERTVAETVVPDRPFWKRGQAEG
>Mature_222_residues
MLEDLKAKNAAWSKSKTAEDPDFFTRLAKQQSPEYLWIGCSDSRVPANEIVGLDPGELFVHRNVANLAPPQDANYLSVLQ
FAVDVLKVKHIMVVGHYGCGGVAAAIDGKRRGLVDHWLHPIREVYAEHRPELEAIPEKREMIDRLTELNVARQVRNVAAD
VFVQDAWARGQSLAVHGWVYSLANGLVNDLNVGIASLEDYERTVAETVVPDRPFWKRGQAEG

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=201, Percent_Identity=50.7462686567164, Blast_Score=221, Evalue=4e-59,
Organism=Escherichia coli, GI1786534, Length=191, Percent_Identity=32.9842931937173, Blast_Score=89, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324292, Length=194, Percent_Identity=35.0515463917526, Blast_Score=115, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24777; Mature: 24777

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEDLKAKNAAWSKSKTAEDPDFFTRLAKQQSPEYLWIGCSDSRVPANEIVGLDPGELFV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHCCCCCCHHEEE
HRNVANLAPPQDANYLSVLQFAVDVLKVKHIMVVGHYGCGGVAAAIDGKRRGLVDHWLHP
ECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHCCCCCCHHHHHHHH
IREVYAEHRPELEAIPEKREMIDRLTELNVARQVRNVAADVFVQDAWARGQSLAVHGWVY
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHH
SLANGLVNDLNVGIASLEDYERTVAETVVPDRPFWKRGQAEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MLEDLKAKNAAWSKSKTAEDPDFFTRLAKQQSPEYLWIGCSDSRVPANEIVGLDPGELFV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHCCCCCCHHEEE
HRNVANLAPPQDANYLSVLQFAVDVLKVKHIMVVGHYGCGGVAAAIDGKRRGLVDHWLHP
ECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHCCCCCCHHHHHHHH
IREVYAEHRPELEAIPEKREMIDRLTELNVARQVRNVAADVFVQDAWARGQSLAVHGWVY
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHH
SLANGLVNDLNVGIASLEDYERTVAETVVPDRPFWKRGQAEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]