| Definition | Caulobacter crescentus CB15 chromosome, complete genome. |
|---|---|
| Accession | NC_002696 |
| Length | 4,016,947 |
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The map label for this gene is yafB [C]
Identifier: 16127658
GI number: 16127658
Start: 3672095
End: 3672934
Strand: Direct
Name: yafB [C]
Synonym: CC_3428
Alternate gene names: 16127658
Gene position: 3672095-3672934 (Clockwise)
Preceding gene: 16127657
Following gene: 16127660
Centisome position: 91.42
GC content: 66.67
Gene sequence:
>840_bases ATGTCCAAGCTTGTTCCCGCCGTCCGCTCGGGCGATGTCCTGATGCCCGCCCTGGGCTTTGGCACCTGGCAGCTGGAGAA CGGAACCGCCGTTCCGCTGGTCGAAAAGGCCCTGGAGATCGGCTACCGCCACATCGACACCGCCCAGATCTACGGCAACG AGCGCGATGTCGGCGCGGCGATCAGGAACAGCGGGGTCAAGCGCGACGAGATCTTCCTGACCACCAAGGTCTGGATCGAC CAGTTCGCGGACGGCGACTTGCAGCGCTCGGCCGAGAAGAGCCTGGAGAAGCTGGGCGTCGACCAGGTCGACCTCCTCTT GCTGCACTGGCCCAAGCCCGAGGTCCCGCTGGCCGAGACCCTGAAGGCCCTGAACGCGGTTCGCGCCAAGGGCTGGACCC GCGCCATCGGCCTGTCGAACTTCCCATCCGCCCAGCTGGAGGAGGCCGCCAAGCTGTCGGAGGCCCCCATCGCCACCGAT CAGGTCGAGTATCACCCCTACCTGTCGCTGAAGACCCTGAAGGCCAAGGCCGACCAGCTGGGCGTGTCGATCACCGCCTG GTCGCCACTGGCCCAGGGCAAGGTCGCGCAGGATCCGGTGCTGATCGAGATCGGCCGCGCCCACGGCAAGACGCCCGGCC AGGTCACCCTGCGCTGGATCATCCAGCAGGGGATCATCGCCATCCCGCGCACCAGCAATCCCAAGCGCATCGAGGAGAAC TTCGACATCCTCGACTTCGAGCTGTCGGAGAAGGAGATGGCGCAGATCCACGGCCTGGCGCGCCCGGACGGGCGGATCGG GGATTGGATCGATCGGGCGTATGCCTGGGACGCTGAGTAG
Upstream 100 bases:
>100_bases TGGTCGCGCTGATCTTCATCGCCCTCTCGCGCGTTCGGGCCAGGGTGGCGCCCAGCCACAGCGAGCCCCTATCGGCCTGA CGCCCTTTTCGGAGCCTTCG
Downstream 100 bases:
>100_bases GGAGCGAGGCCCAGATGTGAACGAATTCTCGGATTGGGAAAGTCAAGCAACTATCTGGGCCTACTACAAGCCCCGCCAAA CTCATGCGTGGAACATGCTG
Product: aldo/keto reductase family oxidoreductase
Products: 2-keto-L-gulonate; NADP [C]
Alternate protein names: NA
Number of amino acids: Translated: 279; Mature: 278
Protein sequence:
>279_residues MSKLVPAVRSGDVLMPALGFGTWQLENGTAVPLVEKALEIGYRHIDTAQIYGNERDVGAAIRNSGVKRDEIFLTTKVWID QFADGDLQRSAEKSLEKLGVDQVDLLLLHWPKPEVPLAETLKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLSEAPIATD QVEYHPYLSLKTLKAKADQLGVSITAWSPLAQGKVAQDPVLIEIGRAHGKTPGQVTLRWIIQQGIIAIPRTSNPKRIEEN FDILDFELSEKEMAQIHGLARPDGRIGDWIDRAYAWDAE
Sequences:
>Translated_279_residues MSKLVPAVRSGDVLMPALGFGTWQLENGTAVPLVEKALEIGYRHIDTAQIYGNERDVGAAIRNSGVKRDEIFLTTKVWID QFADGDLQRSAEKSLEKLGVDQVDLLLLHWPKPEVPLAETLKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLSEAPIATD QVEYHPYLSLKTLKAKADQLGVSITAWSPLAQGKVAQDPVLIEIGRAHGKTPGQVTLRWIIQQGIIAIPRTSNPKRIEEN FDILDFELSEKEMAQIHGLARPDGRIGDWIDRAYAWDAE >Mature_278_residues SKLVPAVRSGDVLMPALGFGTWQLENGTAVPLVEKALEIGYRHIDTAQIYGNERDVGAAIRNSGVKRDEIFLTTKVWIDQ FADGDLQRSAEKSLEKLGVDQVDLLLLHWPKPEVPLAETLKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLSEAPIATDQ VEYHPYLSLKTLKAKADQLGVSITAWSPLAQGKVAQDPVLIEIGRAHGKTPGQVTLRWIIQQGIIAIPRTSNPKRIEENF DILDFELSEKEMAQIHGLARPDGRIGDWIDRAYAWDAE
Specific function: Reduction [C]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI24497577, Length=281, Percent_Identity=35.5871886120996, Blast_Score=184, Evalue=8e-47, Organism=Homo sapiens, GI5174391, Length=281, Percent_Identity=35.5871886120996, Blast_Score=184, Evalue=8e-47, Organism=Homo sapiens, GI93277124, Length=300, Percent_Identity=33.3333333333333, Blast_Score=164, Evalue=1e-40, Organism=Homo sapiens, GI223468663, Length=283, Percent_Identity=33.2155477031802, Blast_Score=163, Evalue=2e-40, Organism=Homo sapiens, GI24497585, Length=288, Percent_Identity=34.0277777777778, Blast_Score=162, Evalue=3e-40, Organism=Homo sapiens, GI310109922, Length=269, Percent_Identity=32.7137546468402, Blast_Score=160, Evalue=1e-39, Organism=Homo sapiens, GI5453543, Length=288, Percent_Identity=32.2916666666667, Blast_Score=159, Evalue=2e-39, Organism=Homo sapiens, GI310109920, Length=288, Percent_Identity=31.9444444444444, Blast_Score=156, Evalue=2e-38, Organism=Homo sapiens, GI45446745, Length=288, Percent_Identity=31.9444444444444, Blast_Score=156, Evalue=2e-38, Organism=Homo sapiens, GI4503285, Length=288, Percent_Identity=31.9444444444444, Blast_Score=156, Evalue=2e-38, Organism=Homo sapiens, GI4502049, Length=283, Percent_Identity=34.982332155477, Blast_Score=155, Evalue=4e-38, Organism=Homo sapiens, GI24497583, Length=289, Percent_Identity=33.2179930795848, Blast_Score=154, Evalue=1e-37, Organism=Homo sapiens, GI5174695, Length=288, Percent_Identity=32.6388888888889, Blast_Score=152, Evalue=3e-37, Organism=Homo sapiens, GI291291012, Length=264, Percent_Identity=31.4393939393939, Blast_Score=137, Evalue=9e-33, Organism=Homo sapiens, GI300116273, Length=270, Percent_Identity=31.4814814814815, Blast_Score=135, Evalue=5e-32, Organism=Homo sapiens, GI300116271, Length=266, Percent_Identity=31.9548872180451, Blast_Score=130, Evalue=1e-30, Organism=Homo sapiens, GI310109926, Length=105, Percent_Identity=40.9523809523809, Blast_Score=86, Evalue=5e-17, Organism=Homo sapiens, GI207028673, Length=105, Percent_Identity=40.9523809523809, Blast_Score=86, Evalue=5e-17, Organism=Homo sapiens, GI310109924, Length=145, Percent_Identity=29.6551724137931, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI27436969, Length=202, Percent_Identity=29.7029702970297, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI4504825, Length=202, Percent_Identity=29.7029702970297, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI27436964, Length=204, Percent_Identity=27.4509803921569, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI27436962, Length=202, Percent_Identity=27.2277227722772, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI27436971, Length=203, Percent_Identity=27.0935960591133, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI27436966, Length=204, Percent_Identity=27.4509803921569, Blast_Score=69, Evalue=4e-12, Organism=Escherichia coli, GI1786400, Length=264, Percent_Identity=40.530303030303, Blast_Score=191, Evalue=5e-50, Organism=Escherichia coli, GI87082198, Length=261, Percent_Identity=37.9310344827586, Blast_Score=183, Evalue=1e-47, Organism=Escherichia coli, GI1788081, Length=266, Percent_Identity=33.4586466165414, Blast_Score=122, Evalue=3e-29, Organism=Escherichia coli, GI1787674, Length=281, Percent_Identity=27.4021352313167, Blast_Score=94, Evalue=8e-21, Organism=Escherichia coli, GI87081735, Length=298, Percent_Identity=26.8456375838926, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI48994888, Length=194, Percent_Identity=30.9278350515464, Blast_Score=75, Evalue=7e-15, Organism=Escherichia coli, GI1789375, Length=306, Percent_Identity=23.8562091503268, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1788070, Length=317, Percent_Identity=23.6593059936909, Blast_Score=66, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17537075, Length=294, Percent_Identity=34.3537414965986, Blast_Score=176, Evalue=2e-44, Organism=Caenorhabditis elegans, GI17537077, Length=292, Percent_Identity=33.9041095890411, Blast_Score=175, Evalue=2e-44, Organism=Caenorhabditis elegans, GI71998625, Length=277, Percent_Identity=31.7689530685921, Blast_Score=166, Evalue=1e-41, Organism=Caenorhabditis elegans, GI17566692, Length=288, Percent_Identity=32.6388888888889, Blast_Score=159, Evalue=2e-39, Organism=Caenorhabditis elegans, GI17561298, Length=279, Percent_Identity=30.8243727598566, Blast_Score=152, Evalue=2e-37, Organism=Caenorhabditis elegans, GI17550248, Length=289, Percent_Identity=31.4878892733564, Blast_Score=152, Evalue=3e-37, Organism=Caenorhabditis elegans, GI17564128, Length=284, Percent_Identity=30.2816901408451, Blast_Score=145, Evalue=2e-35, Organism=Caenorhabditis elegans, GI17538386, Length=263, Percent_Identity=30.4182509505703, Blast_Score=138, Evalue=3e-33, Organism=Caenorhabditis elegans, GI17537079, Length=284, Percent_Identity=31.3380281690141, Blast_Score=137, Evalue=4e-33, Organism=Caenorhabditis elegans, GI17552492, Length=281, Percent_Identity=28.8256227758007, Blast_Score=137, Evalue=6e-33, Organism=Caenorhabditis elegans, GI17561300, Length=262, Percent_Identity=28.6259541984733, Blast_Score=123, Evalue=1e-28, Organism=Caenorhabditis elegans, GI17562292, Length=268, Percent_Identity=27.6119402985075, Blast_Score=116, Evalue=1e-26, Organism=Saccharomyces cerevisiae, GI6320576, Length=288, Percent_Identity=35.7638888888889, Blast_Score=164, Evalue=1e-41, Organism=Saccharomyces cerevisiae, GI6324694, Length=281, Percent_Identity=35.2313167259786, Blast_Score=162, Evalue=4e-41, Organism=Saccharomyces cerevisiae, GI6322556, Length=255, Percent_Identity=30.9803921568627, Blast_Score=140, Evalue=3e-34, Organism=Saccharomyces cerevisiae, GI6321896, Length=326, Percent_Identity=27.3006134969325, Blast_Score=125, Evalue=6e-30, Organism=Saccharomyces cerevisiae, GI6319625, Length=287, Percent_Identity=31.3588850174216, Blast_Score=110, Evalue=2e-25, Organism=Saccharomyces cerevisiae, GI6320079, Length=240, Percent_Identity=32.0833333333333, Blast_Score=103, Evalue=2e-23, Organism=Drosophila melanogaster, GI24663317, Length=290, Percent_Identity=36.551724137931, Blast_Score=175, Evalue=3e-44, Organism=Drosophila melanogaster, GI24644950, Length=296, Percent_Identity=35.472972972973, Blast_Score=172, Evalue=2e-43, Organism=Drosophila melanogaster, GI221378297, Length=316, Percent_Identity=32.5949367088608, Blast_Score=167, Evalue=9e-42, Organism=Drosophila melanogaster, GI20129731, Length=282, Percent_Identity=34.7517730496454, Blast_Score=166, Evalue=2e-41, Organism=Drosophila melanogaster, GI24657054, Length=272, Percent_Identity=34.5588235294118, Blast_Score=163, Evalue=9e-41, Organism=Drosophila melanogaster, GI21356425, Length=287, Percent_Identity=33.4494773519164, Blast_Score=159, Evalue=2e-39, Organism=Drosophila melanogaster, GI24662789, Length=281, Percent_Identity=33.4519572953737, Blast_Score=154, Evalue=6e-38, Organism=Drosophila melanogaster, GI45553081, Length=286, Percent_Identity=31.4685314685315, Blast_Score=149, Evalue=2e-36, Organism=Drosophila melanogaster, GI24662781, Length=269, Percent_Identity=35.6877323420074, Blast_Score=144, Evalue=7e-35, Organism=Drosophila melanogaster, GI24662785, Length=269, Percent_Identity=35.3159851301115, Blast_Score=143, Evalue=1e-34, Organism=Drosophila melanogaster, GI281366140, Length=248, Percent_Identity=30.241935483871, Blast_Score=127, Evalue=1e-29, Organism=Drosophila melanogaster, GI24640980, Length=193, Percent_Identity=25.9067357512953, Blast_Score=64, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: NA
Molecular weight: Translated: 30816; Mature: 30684
Theoretical pI: Translated: 5.44; Mature: 5.44
Prosite motif: PS00798 ALDOKETO_REDUCTASE_1 ; PS00062 ALDOKETO_REDUCTASE_2 ; PS00063 ALDOKETO_REDUCTASE_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.1 %Met (Translated Protein) 1.1 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 0.7 %Met (Mature Protein) 0.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSKLVPAVRSGDVLMPALGFGTWQLENGTAVPLVEKALEIGYRHIDTAQIYGNERDVGAA CCCCCCCCCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHCCCCCCHHEECCCCCHHHHH IRNSGVKRDEIFLTTKVWIDQFADGDLQRSAEKSLEKLGVDQVDLLLLHWPKPEVPLAET HHHCCCCCHHEEEEHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHH LKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLSEAPIATDQVEYHPYLSLKTLKAKADQL HHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCEEEHHHHHHHHHH GVSITAWSPLAQGKVAQDPVLIEIGRAHGKTPGQVTLRWIIQQGIIAIPRTSNPKRIEEN CEEEEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCEEECCCCCCCHHHCC FDILDFELSEKEMAQIHGLARPDGRIGDWIDRAYAWDAE CCEEEEECCHHHHHHHHCCCCCCCCHHHHHHHCCCCCCC >Mature Secondary Structure SKLVPAVRSGDVLMPALGFGTWQLENGTAVPLVEKALEIGYRHIDTAQIYGNERDVGAA CCCCCCCCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHCCCCCCHHEECCCCCHHHHH IRNSGVKRDEIFLTTKVWIDQFADGDLQRSAEKSLEKLGVDQVDLLLLHWPKPEVPLAET HHHCCCCCHHEEEEHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHH LKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLSEAPIATDQVEYHPYLSLKTLKAKADQL HHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCEEEHHHHHHHHHH GVSITAWSPLAQGKVAQDPVLIEIGRAHGKTPGQVTLRWIIQQGIIAIPRTSNPKRIEEN CEEEEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCEEECCCCCCCHHHCC FDILDFELSEKEMAQIHGLARPDGRIGDWIDRAYAWDAE CCEEEEECCHHHHHHHHCCCCCCCCHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: 2,5-diketo-D-gluconate; NADPH [C]
Specific reaction: 2,5-diketo-D-gluconate + NADPH = 2-keto-L-gulonate + NADP [C]
General reaction: Oxidoreductases [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA