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The map label for this gene is mcpA [H]

Identifier: 16127579

GI number: 16127579

Start: 3595840

End: 3597609

Strand: Direct

Name: mcpA [H]

Synonym: CC_3349

Alternate gene names: 16127579

Gene position: 3595840-3597609 (Clockwise)

Preceding gene: 16127578

Following gene: 16127586

Centisome position: 89.52

GC content: 64.92

Gene sequence:

>1770_bases
ATGTTTTACCCGAAATTCACCGAGACAAATCAGCGTTATATGGACTTGGGCGGTGTTCCGCCTCGCAAGACGCACGGATC
GCGGCGAATGATCAAACTTCTGAACGGCTCCGCGGGCGACGCCAGCCAGAAGATCGACGCACTCGACAAGTCGCTCGCGA
TGATCGAGTTCGACGTCAAGGGAACGATCCTCGCGGCCAACGCCAACTTCTGCAAAGCCATGGGCTATGAGGCGCGGGAG
ATCATCGGCAAGCACCACAGCCTGTTCGTGGATCCCGAATACGCCGCCAGCCAGGCCTATCGCGACTTTTGGATGCAGCT
GGGCCAGGGCCAGTTCGACGCGCGGGAGTATCTGCGCCTGGGCAAGGGCGGCAGGGAAGTCTGGATCCAGGCCTCCTACA
ACCCGGTCAAGAACAGCGCCGGCAAGGTGACCCGGATTCTGAAGGTCGCGACCGACATCACGGCTCAGAAAGAGGTCGAA
GCCGAGCGGACGGCCAAGCTCGACGCCGTGGAACGCGTGCAGGCCACGATCGAATTCACGGTCGACGGCGTCATCCTGAA
CGCCAACGAGAACTTCCTGGCCACCGTCGGCTATGCGCTGTCCGAGATCCAGGGCAAGCATCACAGCATGTTCGTCGATC
CGGCCGAAGCGCGCTCGGAGGCCTATGCCGCATTCTGGCGCCGGCTGAACACCGGCGAGTTCGTCGCCGCAGAGTTCCGG
CGGATAGGCAAGGGCGGCAAGGAGGTCTGGATCCAGGCGTCCTACAATCCGGTGTTCGACGCCAAGGGTCGGGTGGTCAA
GGTCGTCAAGTTCGCGACCGACGTGACCGGCCGCGTCGATGCGGTCAATCAGATCGCCCAGGCCCTGGCGCGTCTCGCCG
CCAACGATCTGAGCTATCGGATGGCGGCGCAGATCGACGCCCAGTTCGCCTCTGTCCGCGACGACTTCAACGACGCCGTG
GCCGCGCTTGATGAAACGATTGGAGCGGTCGCCTCGGCCACACGGAACGTCGCCACCGGCGCCAATGAAATCTCGACCGC
GTCGGACAATCTCTCGCGGCGTACGGAGCAGCAGGCCGCCAGTCTTGAAGAAACCGCTGCGGCGCTGGATGAGATCACCG
CCACGGTCAGCCGCAGCGCCGACGGCGCCAAGCGCGCGTCGGTGGCGGCCTCCGATGCGCGCGTTGACGCGGCCAAGTCC
GGAGAGATCGTCGGAGAAGCGGTCTCGGCGATGGATGGCATCGAGTCGAGCTCCAACCAGATCAACCAGATCATCAGCGT
GATCGACGAGATCGCCTTCCAGACTAACCTTCTGGCCCTGAACGCCGGCGTCGAGGCCGCGCGCGCAGGCGAGGCGGGCC
GAGGCTTCGCCGTGGTGGCTCAGGAAGTGCGCGCCCTGGCGCAACGCTCGGCCGAAGCCGCCAAGGAGATCAAGGTCCTG
ATCGCCAACAGCTCAACCCAGGTCGAACGCGGGGTGAAACTGGTCGGCGAAACCGGCCGCGCCTTGCAATCGATCGTCAG
CAAGGTGAGCGAGATCGACACCCTGATCAGCGAGATCGCCCAGTCGTCGCGGGAGCAGGCGACAGGGCTGGGCGAGGTCA
ATGTGGCCGTCAACCAGATGGACCAGGTCACCCAGCAGAACGCGGCCATGGTGGAGGAAGCGACGGCGGCGGCGGCGAGC
CTGCGCCACGAAGCCGACGAACTCGACAAGCTGATCGCGCGCTTCCATGTGACGGCGCGCGCGGCCCGTCGTCCCCGGCT
GGTGGCGTAG

Upstream 100 bases:

>100_bases
CATCGCCGGTCTTTGAGATTGAAAATCAAGACGCCGCTGCAATTCCAGAAACGCCCCCAATCCGAGCTGAGCGACAAAAG
GCCACACTATTCGAAAGGTT

Downstream 100 bases:

>100_bases
GATCATCAACCGCCCCCCGCGCGCCCCCCGCGCCGGCTGATGGGCCACATCAGATCGGGTGAAGAGAGCTGTCCTTGGCC
GCCGACAAGGGGGCCGGCGG

Product: methyl-accepting chemotaxis protein McpH

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 589; Mature: 589

Protein sequence:

>589_residues
MFYPKFTETNQRYMDLGGVPPRKTHGSRRMIKLLNGSAGDASQKIDALDKSLAMIEFDVKGTILAANANFCKAMGYEARE
IIGKHHSLFVDPEYAASQAYRDFWMQLGQGQFDAREYLRLGKGGREVWIQASYNPVKNSAGKVTRILKVATDITAQKEVE
AERTAKLDAVERVQATIEFTVDGVILNANENFLATVGYALSEIQGKHHSMFVDPAEARSEAYAAFWRRLNTGEFVAAEFR
RIGKGGKEVWIQASYNPVFDAKGRVVKVVKFATDVTGRVDAVNQIAQALARLAANDLSYRMAAQIDAQFASVRDDFNDAV
AALDETIGAVASATRNVATGANEISTASDNLSRRTEQQAASLEETAAALDEITATVSRSADGAKRASVAASDARVDAAKS
GEIVGEAVSAMDGIESSSNQINQIISVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVRALAQRSAEAAKEIKVL
IANSSTQVERGVKLVGETGRALQSIVSKVSEIDTLISEIAQSSREQATGLGEVNVAVNQMDQVTQQNAAMVEEATAAAAS
LRHEADELDKLIARFHVTARAARRPRLVA

Sequences:

>Translated_589_residues
MFYPKFTETNQRYMDLGGVPPRKTHGSRRMIKLLNGSAGDASQKIDALDKSLAMIEFDVKGTILAANANFCKAMGYEARE
IIGKHHSLFVDPEYAASQAYRDFWMQLGQGQFDAREYLRLGKGGREVWIQASYNPVKNSAGKVTRILKVATDITAQKEVE
AERTAKLDAVERVQATIEFTVDGVILNANENFLATVGYALSEIQGKHHSMFVDPAEARSEAYAAFWRRLNTGEFVAAEFR
RIGKGGKEVWIQASYNPVFDAKGRVVKVVKFATDVTGRVDAVNQIAQALARLAANDLSYRMAAQIDAQFASVRDDFNDAV
AALDETIGAVASATRNVATGANEISTASDNLSRRTEQQAASLEETAAALDEITATVSRSADGAKRASVAASDARVDAAKS
GEIVGEAVSAMDGIESSSNQINQIISVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVRALAQRSAEAAKEIKVL
IANSSTQVERGVKLVGETGRALQSIVSKVSEIDTLISEIAQSSREQATGLGEVNVAVNQMDQVTQQNAAMVEEATAAAAS
LRHEADELDKLIARFHVTARAARRPRLVA
>Mature_589_residues
MFYPKFTETNQRYMDLGGVPPRKTHGSRRMIKLLNGSAGDASQKIDALDKSLAMIEFDVKGTILAANANFCKAMGYEARE
IIGKHHSLFVDPEYAASQAYRDFWMQLGQGQFDAREYLRLGKGGREVWIQASYNPVKNSAGKVTRILKVATDITAQKEVE
AERTAKLDAVERVQATIEFTVDGVILNANENFLATVGYALSEIQGKHHSMFVDPAEARSEAYAAFWRRLNTGEFVAAEFR
RIGKGGKEVWIQASYNPVFDAKGRVVKVVKFATDVTGRVDAVNQIAQALARLAANDLSYRMAAQIDAQFASVRDDFNDAV
AALDETIGAVASATRNVATGANEISTASDNLSRRTEQQAASLEETAAALDEITATVSRSADGAKRASVAASDARVDAAKS
GEIVGEAVSAMDGIESSSNQINQIISVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVRALAQRSAEAAKEIKVL
IANSSTQVERGVKLVGETGRALQSIVSKVSEIDTLISEIAQSSREQATGLGEVNVAVNQMDQVTQQNAAMVEEATAAAAS
LRHEADELDKLIARFHVTARAARRPRLVA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=288, Percent_Identity=48.2638888888889, Blast_Score=215, Evalue=6e-57,
Organism=Escherichia coli, GI1787690, Length=292, Percent_Identity=43.1506849315069, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI2367378, Length=269, Percent_Identity=46.4684014869888, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1788195, Length=258, Percent_Identity=49.2248062015504, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI1789453, Length=253, Percent_Identity=40.3162055335968, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI87081921, Length=464, Percent_Identity=21.551724137931, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 63350; Mature: 63350

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYPKFTETNQRYMDLGGVPPRKTHGSRRMIKLLNGSAGDASQKIDALDKSLAMIEFDVK
CCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEEECC
GTILAANANFCKAMGYEAREIIGKHHSLFVDPEYAASQAYRDFWMQLGQGQFDAREYLRL
CEEEEECCHHHHHCCCHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHH
GKGGREVWIQASYNPVKNSAGKVTRILKVATDITAQKEVEAERTAKLDAVERVQATIEFT
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
VDGVILNANENFLATVGYALSEIQGKHHSMFVDPAEARSEAYAAFWRRLNTGEFVAAEFR
EEEEEEECCCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHCCCCHHHHHHHH
RIGKGGKEVWIQASYNPVFDAKGRVVKVVKFATDVTGRVDAVNQIAQALARLAANDLSYR
HHCCCCCEEEEEECCCCCCCCCCCEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
MAAQIDAQFASVRDDFNDAVAALDETIGAVASATRNVATGANEISTASDNLSRRTEQQAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHH
SLEETAAALDEITATVSRSADGAKRASVAASDARVDAAKSGEIVGEAVSAMDGIESSSNQ
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHCCCCCHHH
INQIISVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVRALAQRSAEAAKEIKVL
HHHHHHHHHHHHHHHCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEE
IANSSTQVERGVKLVGETGRALQSIVSKVSEIDTLISEIAQSSREQATGLGEVNVAVNQM
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
DQVTQQNAAMVEEATAAAASLRHEADELDKLIARFHVTARAARRPRLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFYPKFTETNQRYMDLGGVPPRKTHGSRRMIKLLNGSAGDASQKIDALDKSLAMIEFDVK
CCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEEECC
GTILAANANFCKAMGYEAREIIGKHHSLFVDPEYAASQAYRDFWMQLGQGQFDAREYLRL
CEEEEECCHHHHHCCCHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHH
GKGGREVWIQASYNPVKNSAGKVTRILKVATDITAQKEVEAERTAKLDAVERVQATIEFT
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
VDGVILNANENFLATVGYALSEIQGKHHSMFVDPAEARSEAYAAFWRRLNTGEFVAAEFR
EEEEEEECCCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHCCCCHHHHHHHH
RIGKGGKEVWIQASYNPVFDAKGRVVKVVKFATDVTGRVDAVNQIAQALARLAANDLSYR
HHCCCCCEEEEEECCCCCCCCCCCEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
MAAQIDAQFASVRDDFNDAVAALDETIGAVASATRNVATGANEISTASDNLSRRTEQQAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHH
SLEETAAALDEITATVSRSADGAKRASVAASDARVDAAKSGEIVGEAVSAMDGIESSSNQ
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHCCCCCHHH
INQIISVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVRALAQRSAEAAKEIKVL
HHHHHHHHHHHHHHHCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEE
IANSSTQVERGVKLVGETGRALQSIVSKVSEIDTLISEIAQSSREQATGLGEVNVAVNQM
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
DQVTQQNAAMVEEATAAAASLRHEADELDKLIARFHVTARAARRPRLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]