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The map label for this gene is regX3 [H]

Identifier: 16127555

GI number: 16127555

Start: 3571971

End: 3572681

Strand: Direct

Name: regX3 [H]

Synonym: CC_3325

Alternate gene names: 16127555

Gene position: 3571971-3572681 (Clockwise)

Preceding gene: 16127554

Following gene: 16127556

Centisome position: 88.92

GC content: 65.68

Gene sequence:

>711_bases
ATGAAAGTCGCCCTGCTCGACGACGACCAAAGTCACAACGCGCTCGTGGCTTCGGTTCTGGAGCCCGCCGGATTCGTCTG
CACCAGCTTCACGACGCCGTCGCGCTTGCTGGCCGAGCTGCGCAAACAGACCTTCGATCTGATCATTCTCGACTGGAACA
TGCCCGAGCTGTCCGGCGTCGAGACCTTGAAGCTTCTGCGGGAGGATCCCGCGACGGCCCCGCCCGTGCTGCTGCTCACC
AGTCGGTCGGTGGAGGCCGATCTCGTCGAGGGCCTGAACGCCGGCGCCGACGACTACATCGTCAAGCCGCTGCAGCCGCA
GGTGCTGCTGGCGCGCGTGAACGCCGTTGTCCGGCGCATCCATCGGCCGGCGTCACAGCCGCAGACGGAACAGTATGGAC
ACTACCGACTGGACCCCGGCGCCCAGACCGCCAGCTGGAACGGCCAGGTCGAGGCCCTGACACCCAAGGAGTTCCAGTTG
GCTTCGCTGCTGTTCAGCAATCTCTCACGGCCCCTGTCGCGGGAGTATCTGTTGCGGCGCATCTGGGGGCAGAGGCCGGA
CCTGGAGACCCGCACCCTGGACGCCCATGTCTCTCGGCTGCGCTCAAAGCTTCACCTTCGTCCCAGCAACGGTTTCCGGC
TGAGCACGGTCTACGGTTTCGGCTATCGTCTTGAGGCGTGCGACCCGGATACGGCGGGCGGGGGAGACTGA

Upstream 100 bases:

>100_bases
GAACAGCTGGACGCCTGCTTGTCGCCCCACCGACAGAGAGTCGCCCGCGGCGCGTTCCGCTCCCCCGCGGGACGCGCCAC
TTCCCAGCTTAAGTGAGCTT

Downstream 100 bases:

>100_bases
GCATGATCAAGGCCGCTGGGGTGAGTTTCGTGGTTCTGGCGCTGGCGGGCGGCGCGAGCGCCTGGGCCCAGACCCCGCCC
GCCGAGCCGCCGGTGGCCTA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKVALLDDDQSHNALVASVLEPAGFVCTSFTTPSRLLAELRKQTFDLIILDWNMPELSGVETLKLLREDPATAPPVLLLT
SRSVEADLVEGLNAGADDYIVKPLQPQVLLARVNAVVRRIHRPASQPQTEQYGHYRLDPGAQTASWNGQVEALTPKEFQL
ASLLFSNLSRPLSREYLLRRIWGQRPDLETRTLDAHVSRLRSKLHLRPSNGFRLSTVYGFGYRLEACDPDTAGGGD

Sequences:

>Translated_236_residues
MKVALLDDDQSHNALVASVLEPAGFVCTSFTTPSRLLAELRKQTFDLIILDWNMPELSGVETLKLLREDPATAPPVLLLT
SRSVEADLVEGLNAGADDYIVKPLQPQVLLARVNAVVRRIHRPASQPQTEQYGHYRLDPGAQTASWNGQVEALTPKEFQL
ASLLFSNLSRPLSREYLLRRIWGQRPDLETRTLDAHVSRLRSKLHLRPSNGFRLSTVYGFGYRLEACDPDTAGGGD
>Mature_236_residues
MKVALLDDDQSHNALVASVLEPAGFVCTSFTTPSRLLAELRKQTFDLIILDWNMPELSGVETLKLLREDPATAPPVLLLT
SRSVEADLVEGLNAGADDYIVKPLQPQVLLARVNAVVRRIHRPASQPQTEQYGHYRLDPGAQTASWNGQVEALTPKEFQL
ASLLFSNLSRPLSREYLLRRIWGQRPDLETRTLDAHVSRLRSKLHLRPSNGFRLSTVYGFGYRLEACDPDTAGGGD

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=36.4444444444444, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=35.8744394618834, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=34.375, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=30.9734513274336, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=35.3711790393013, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=31.1111111111111, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=32.9004329004329, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=35.2422907488987, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=31.6964285714286, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=31.4655172413793, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=31.1688311688312, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=25.3275109170306, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787375, Length=180, Percent_Identity=30.5555555555556, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1790437, Length=146, Percent_Identity=31.5068493150685, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788191, Length=122, Percent_Identity=29.5081967213115, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=25.2173913043478, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26255; Mature: 26255

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVALLDDDQSHNALVASVLEPAGFVCTSFTTPSRLLAELRKQTFDLIILDWNMPELSGV
CEEEEECCCCCCCHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCEEEEEEECCCCCCCCH
ETLKLLREDPATAPPVLLLTSRSVEADLVEGLNAGADDYIVKPLQPQVLLARVNAVVRRI
HHHHHHHHCCCCCCCEEEEECCCCHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHH
HRPASQPQTEQYGHYRLDPGAQTASWNGQVEALTPKEFQLASLLFSNLSRPLSREYLLRR
HCCCCCCCCHHCCCEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHH
IWGQRPDLETRTLDAHVSRLRSKLHLRPSNGFRLSTVYGFGYRLEACDPDTAGGGD
HHCCCCCCCHHHHHHHHHHHHHHEECCCCCCEEEEEEECCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MKVALLDDDQSHNALVASVLEPAGFVCTSFTTPSRLLAELRKQTFDLIILDWNMPELSGV
CEEEEECCCCCCCHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCEEEEEEECCCCCCCCH
ETLKLLREDPATAPPVLLLTSRSVEADLVEGLNAGADDYIVKPLQPQVLLARVNAVVRRI
HHHHHHHHCCCCCCCEEEEECCCCHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHH
HRPASQPQTEQYGHYRLDPGAQTASWNGQVEALTPKEFQLASLLFSNLSRPLSREYLLRR
HCCCCCCCCHHCCCEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHH
IWGQRPDLETRTLDAHVSRLRSKLHLRPSNGFRLSTVYGFGYRLEACDPDTAGGGD
HHCCCCCCCHHHHHHHHHHHHHHEECCCCCCEEEEEEECCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA