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The map label for this gene is suhB

Identifier: 16127499

GI number: 16127499

Start: 3524882

End: 3525652

Strand: Direct

Name: suhB

Synonym: CC_3269

Alternate gene names: 16127499

Gene position: 3524882-3525652 (Clockwise)

Preceding gene: 16127495

Following gene: 16127502

Centisome position: 87.75

GC content: 67.44

Gene sequence:

>771_bases
ATGATCGAAGCGGCTCGGAAGGCCGCCCGTGGCCTGGCTCGTGACTTCGGCGAAGTCACCGAACTGCAGGTCTCCAAGAA
GGGCGCGGCGGACTTCGTCACCAACGCCGACATCAAGGCCGAACAGACCCTGTTCGAACTGCTGACCAAGGCCCGCCCCG
GCTACGGCTTCCTCGGGGAAGAGCGCGGGATGGTCGAGGGCACCGACAAGACCCACACCTGGATCGTCGACCCGCTGGAC
GGCACCACCAACTTCATGCACGCCATCCCGCACTTTGCGGTGAACATCGCCTTGCAGCGCGAGGGCGAAGGCATCGTCGC
CGGCGTCACCTACAACCCCATCACCAACGACCTGTTCTGGGTCGAAAAGGGCAAGGGCGCCTTCCTGGGCGCCGAAAAGC
GCCTGCGCGTCGCCGCCCGCCGCCACCTGGACGAGGCGATCCTCGCCACCGGCGTGCCGTTCGCCGGCAAGCCGGGCCAC
GGCCAGTTCCTGAAAGAGCTGCACCAGGTCAGCCAGAAGGTCGCCGGCGTCCGTCGCTTCGGCGCGGCCTCGCTGGACCT
GGCCTGGGTCGCCGCGGGTCGTTTCGACGCCTTCTGGGAGCGCAACCTCAACAGCTGGGACGTCGCGGCCGGCGTGCTGA
TGATCCAGGAGTCGGGCGGCAAGATCACCACGATCGACGAGAGCGACCACGACGTCGTCCAGGGCAAGTCGATCCTGGCC
AGCAACCAGGACCTCCACCCGCAGATCCTGGAACGCCTGCGGGCGGCTTAG

Upstream 100 bases:

>100_bases
ACCGTCGACCTACCGCTCCGCCGCCGGACTTTCCGGCGGGCGTCGACGGCTTCTTGAGGATAGCCCGCCCGTGCCCACGC
CCTCCGCCCTGCTGAACGTC

Downstream 100 bases:

>100_bases
TCCGTCTGTTCGCTGGAGCCCCGGCGATCTATCCGCAGGATGTCGCCGGGCTCGCAGTCCAGAAATTCACAGATCTTCTC
AAGCGTCTCGAACCGAACGC

Product: extragenic suppressor protein SuhB

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MIEAARKAARGLARDFGEVTELQVSKKGAADFVTNADIKAEQTLFELLTKARPGYGFLGEERGMVEGTDKTHTWIVDPLD
GTTNFMHAIPHFAVNIALQREGEGIVAGVTYNPITNDLFWVEKGKGAFLGAEKRLRVAARRHLDEAILATGVPFAGKPGH
GQFLKELHQVSQKVAGVRRFGAASLDLAWVAAGRFDAFWERNLNSWDVAAGVLMIQESGGKITTIDESDHDVVQGKSILA
SNQDLHPQILERLRAA

Sequences:

>Translated_256_residues
MIEAARKAARGLARDFGEVTELQVSKKGAADFVTNADIKAEQTLFELLTKARPGYGFLGEERGMVEGTDKTHTWIVDPLD
GTTNFMHAIPHFAVNIALQREGEGIVAGVTYNPITNDLFWVEKGKGAFLGAEKRLRVAARRHLDEAILATGVPFAGKPGH
GQFLKELHQVSQKVAGVRRFGAASLDLAWVAAGRFDAFWERNLNSWDVAAGVLMIQESGGKITTIDESDHDVVQGKSILA
SNQDLHPQILERLRAA
>Mature_256_residues
MIEAARKAARGLARDFGEVTELQVSKKGAADFVTNADIKAEQTLFELLTKARPGYGFLGEERGMVEGTDKTHTWIVDPLD
GTTNFMHAIPHFAVNIALQREGEGIVAGVTYNPITNDLFWVEKGKGAFLGAEKRLRVAARRHLDEAILATGVPFAGKPGH
GQFLKELHQVSQKVAGVRRFGAASLDLAWVAAGRFDAFWERNLNSWDVAAGVLMIQESGGKITTIDESDHDVVQGKSILA
SNQDLHPQILERLRAA

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family

Homologues:

Organism=Homo sapiens, GI5031789, Length=258, Percent_Identity=31.0077519379845, Blast_Score=121, Evalue=6e-28,
Organism=Homo sapiens, GI221625487, Length=257, Percent_Identity=31.1284046692607, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI7657236, Length=237, Percent_Identity=31.6455696202532, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI221625507, Length=137, Percent_Identity=37.2262773722628, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1788882, Length=253, Percent_Identity=40.7114624505929, Blast_Score=189, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI193202570, Length=255, Percent_Identity=34.1176470588235, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI193202572, Length=252, Percent_Identity=34.1269841269841, Blast_Score=128, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320493, Length=207, Percent_Identity=35.2657004830918, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6321836, Length=230, Percent_Identity=30, Blast_Score=102, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24664922, Length=243, Percent_Identity=34.5679012345679, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24664926, Length=237, Percent_Identity=31.2236286919831, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI21357329, Length=249, Percent_Identity=30.9236947791165, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24664918, Length=262, Percent_Identity=30.9160305343511, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21357957, Length=259, Percent_Identity=33.976833976834, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21357303, Length=225, Percent_Identity=31.1111111111111, Blast_Score=117, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SUHB_CAUCR (Q9A3D5)

Other databases:

- EMBL:   AE005673
- PIR:   C87654
- RefSeq:   NP_422063.1
- ProteinModelPortal:   Q9A3D5
- SMR:   Q9A3D5
- GeneID:   940933
- GenomeReviews:   AE005673_GR
- KEGG:   ccr:CC_3269
- NMPDR:   fig|190650.1.peg.3243
- TIGR:   CC_3269
- HOGENOM:   HBG730251
- OMA:   TGFPFKQ
- ProtClustDB:   CLSK891386
- BRENDA:   3.1.3.25
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337
- PANTHER:   PTHR20854
- PRINTS:   PR00377
- PRINTS:   PR01959

Pfam domain/function: PF00459 Inositol_P

EC number: =3.1.3.25

Molecular weight: Translated: 27927; Mature: 27927

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00629 IMP_1; PS00630 IMP_2

Important sites: BINDING 60-60 BINDING 178-178 BINDING 207-207

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEAARKAARGLARDFGEVTELQVSKKGAADFVTNADIKAEQTLFELLTKARPGYGFLGE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCC
ERGMVEGTDKTHTWIVDPLDGTTNFMHAIPHFAVNIALQREGEGIVAGVTYNPITNDLFW
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHEEEEEEEECCCEEEEEEEECCCCCCEEE
VEKGKGAFLGAEKRLRVAARRHLDEAILATGVPFAGKPGHGQFLKELHQVSQKVAGVRRF
EECCCCCEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GAASLDLAWVAAGRFDAFWERNLNSWDVAAGVLMIQESGGKITTIDESDHDVVQGKSILA
CCCCCCCEEEECCCHHHHHHCCCCCHHHHEEEEEEEECCCEEEEECCCCCHHHHCCHHHC
SNQDLHPQILERLRAA
CCCCCCHHHHHHHHCC
>Mature Secondary Structure
MIEAARKAARGLARDFGEVTELQVSKKGAADFVTNADIKAEQTLFELLTKARPGYGFLGE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCC
ERGMVEGTDKTHTWIVDPLDGTTNFMHAIPHFAVNIALQREGEGIVAGVTYNPITNDLFW
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHEEEEEEEECCCEEEEEEEECCCCCCEEE
VEKGKGAFLGAEKRLRVAARRHLDEAILATGVPFAGKPGHGQFLKELHQVSQKVAGVRRF
EECCCCCEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GAASLDLAWVAAGRFDAFWERNLNSWDVAAGVLMIQESGGKITTIDESDHDVVQGKSILA
CCCCCCCEEEECCCHHHHHHCCCCCHHHHEEEEEEEECCCEEEEECCCCCHHHHCCHHHC
SNQDLHPQILERLRAA
CCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647