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The map label for this gene is cfxB [H]

Identifier: 16127480

GI number: 16127480

Start: 3512670

End: 3513761

Strand: Direct

Name: cfxB [H]

Synonym: CC_3250

Alternate gene names: 16127480

Gene position: 3512670-3513761 (Clockwise)

Preceding gene: 16127479

Following gene: 16127481

Centisome position: 87.45

GC content: 65.2

Gene sequence:

>1092_bases
GTGGCTCGCATCACGCTGCGCCAGCTGTTGGACCATGCCGCCGAGCATGAGTACGGGCTGCCCGCCTTTAATATCAACAA
CATGGAACAGGGCCTGGCGATCATGGAGGCCGCAGATGCGGTCAACTCGCCGGTCATCATCCAGGCCTCGCGCGGCGCGC
GGAACTACGCCAACGACATCATGCTGGCCAAGATGATCGACGCCCTGGTCGACATCTACCCGCACATCCCGGTCTGCATG
CACCAGGACCACGGCAACGGCCCGGCGACCTGCGCCACGGCGATCCAGTATGGCTTCACCTCGGTGATGATGGACGGCTC
GCTGATGGAGGACGCCAAGACCCCCGCCAGCTACGAGTACAACGTCGAAGTGACCCGCAAGGTCGTGCAGATGGCGCACA
GCTGCGGCGTTTCCGTCGAGGGCGAGCTGGGCGTGCTGGGCTCGCTGGAGACCGGCATGGGCGAGGCTGAGGACGGCCAC
GGCTTCGAAGGCAAGCTGTCGCACGACGAGCTGCTGACCGATCCGGACCAGGCGGTCGACTTCGTCGCCCAGACCGGCGT
CGACGCCCTGGCCATCGCCATGGGCACCAGCCACGGCGCCTACAAGTTCACGCGCAAGCCGGACGGCGACGTTCTGGCCA
TGAACGTGATCGAGGAAATCCACCGCCGCCTGCCCAACACCCACCTGGTGATGCACGGCTCCTCGTCGGTCCCTCAGGAC
CTGCAGGACATCATCAACCAGTACGGCGGCGAGATGCCCCAGACCTGGGGCGTGCCGGTCGAAGAGATCCAGCGCGGTAT
CAAGCACGGCGTGCGCAAGATCAATGTCGACACCGACAATCGGATGGCCATCACCGGCGCGATCCGCAAACTGTTGGTCG
AGAAGCCGGGCGAGTTTGATCCCCGCGCCTATCTGAAGCCCGCCAAGGAAGCCATGCGCAAGGTCTGTCAGGCCCGCTTC
GTCGAGTTCGGTTCTGCCGGTCACGCCGACAAAATCAAGCCGATGTCGACCGCGACCATGGCCAAGCGCTACGCGTCCGG
CGAACTGCACGCCAAGTTCGGCGCCAGCGCCGCCAAGGCCGCCGCCGAGTAA

Upstream 100 bases:

>100_bases
CGACTTAAAGACTGACGATCCTGGGCAGAGAGCGCTTCAGCGCCGGGCCCCAAAAACAAGAAACGACCCAAACCACTTAA
CGCTTGCAGGAGAGAAATAC

Downstream 100 bases:

>100_bases
CCGGCGCGATCGAATGGATGTGAAAAAGGGAGGTCTTGGCCTCCCTTTTTTATTCGACCGCCGCGCCCTCGATCAGGGGC
GCGCGGGCGCGCCTGATCCG

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase; Fructose-bisphosphate aldolase II [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MARITLRQLLDHAAEHEYGLPAFNINNMEQGLAIMEAADAVNSPVIIQASRGARNYANDIMLAKMIDALVDIYPHIPVCM
HQDHGNGPATCATAIQYGFTSVMMDGSLMEDAKTPASYEYNVEVTRKVVQMAHSCGVSVEGELGVLGSLETGMGEAEDGH
GFEGKLSHDELLTDPDQAVDFVAQTGVDALAIAMGTSHGAYKFTRKPDGDVLAMNVIEEIHRRLPNTHLVMHGSSSVPQD
LQDIINQYGGEMPQTWGVPVEEIQRGIKHGVRKINVDTDNRMAITGAIRKLLVEKPGEFDPRAYLKPAKEAMRKVCQARF
VEFGSAGHADKIKPMSTATMAKRYASGELHAKFGASAAKAAAE

Sequences:

>Translated_363_residues
MARITLRQLLDHAAEHEYGLPAFNINNMEQGLAIMEAADAVNSPVIIQASRGARNYANDIMLAKMIDALVDIYPHIPVCM
HQDHGNGPATCATAIQYGFTSVMMDGSLMEDAKTPASYEYNVEVTRKVVQMAHSCGVSVEGELGVLGSLETGMGEAEDGH
GFEGKLSHDELLTDPDQAVDFVAQTGVDALAIAMGTSHGAYKFTRKPDGDVLAMNVIEEIHRRLPNTHLVMHGSSSVPQD
LQDIINQYGGEMPQTWGVPVEEIQRGIKHGVRKINVDTDNRMAITGAIRKLLVEKPGEFDPRAYLKPAKEAMRKVCQARF
VEFGSAGHADKIKPMSTATMAKRYASGELHAKFGASAAKAAAE
>Mature_362_residues
ARITLRQLLDHAAEHEYGLPAFNINNMEQGLAIMEAADAVNSPVIIQASRGARNYANDIMLAKMIDALVDIYPHIPVCMH
QDHGNGPATCATAIQYGFTSVMMDGSLMEDAKTPASYEYNVEVTRKVVQMAHSCGVSVEGELGVLGSLETGMGEAEDGHG
FEGKLSHDELLTDPDQAVDFVAQTGVDALAIAMGTSHGAYKFTRKPDGDVLAMNVIEEIHRRLPNTHLVMHGSSSVPQDL
QDIINQYGGEMPQTWGVPVEEIQRGIKHGVRKINVDTDNRMAITGAIRKLLVEKPGEFDPRAYLKPAKEAMRKVCQARFV
EFGSAGHADKIKPMSTATMAKRYASGELHAKFGASAAKAAAE

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI87082041, Length=329, Percent_Identity=33.434650455927, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789526, Length=328, Percent_Identity=33.2317073170732, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788072, Length=329, Percent_Identity=28.8753799392097, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 39300; Mature: 39169

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARITLRQLLDHAAEHEYGLPAFNINNMEQGLAIMEAADAVNSPVIIQASRGARNYANDI
CCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
MLAKMIDALVDIYPHIPVCMHQDHGNGPATCATAIQYGFTSVMMDGSLMEDAKTPASYEY
HHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEE
NVEVTRKVVQMAHSCGVSVEGELGVLGSLETGMGEAEDGHGFEGKLSHDELLTDPDQAVD
CHHHHHHHHHHHHHCCCCCCCCCCEEECHHCCCCCCCCCCCCCCCCCCHHHCCCHHHHHH
FVAQTGVDALAIAMGTSHGAYKFTRKPDGDVLAMNVIEEIHRRLPNTHLVMHGSSSVPQD
HHHHCCCHHEEHHHCCCCCCEEECCCCCCCEEHHHHHHHHHHHCCCCEEEEECCCCCCHH
LQDIINQYGGEMPQTWGVPVEEIQRGIKHGVRKINVDTDNRMAITGAIRKLLVEKPGEFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCCEEHHHHHHHHHHHCCCCCC
PRAYLKPAKEAMRKVCQARFVEFGSAGHADKIKPMSTATMAKRYASGELHAKFGASAAKA
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCHHHHH
AAE
CCC
>Mature Secondary Structure 
ARITLRQLLDHAAEHEYGLPAFNINNMEQGLAIMEAADAVNSPVIIQASRGARNYANDI
CCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
MLAKMIDALVDIYPHIPVCMHQDHGNGPATCATAIQYGFTSVMMDGSLMEDAKTPASYEY
HHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEE
NVEVTRKVVQMAHSCGVSVEGELGVLGSLETGMGEAEDGHGFEGKLSHDELLTDPDQAVD
CHHHHHHHHHHHHHCCCCCCCCCCEEECHHCCCCCCCCCCCCCCCCCCHHHCCCHHHHHH
FVAQTGVDALAIAMGTSHGAYKFTRKPDGDVLAMNVIEEIHRRLPNTHLVMHGSSSVPQD
HHHHCCCHHEEHHHCCCCCCEEECCCCCCCEEHHHHHHHHHHHCCCCEEEEECCCCCCHH
LQDIINQYGGEMPQTWGVPVEEIQRGIKHGVRKINVDTDNRMAITGAIRKLLVEKPGEFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCCEEHHHHHHHHHHHCCCCCC
PRAYLKPAKEAMRKVCQARFVEFGSAGHADKIKPMSTATMAKRYASGELHAKFGASAAKA
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCHHHHH
AAE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1939098 [H]