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The map label for this gene is gapB [H]

Identifier: 16127478

GI number: 16127478

Start: 3510127

End: 3511134

Strand: Direct

Name: gapB [H]

Synonym: CC_3248

Alternate gene names: 16127478

Gene position: 3510127-3511134 (Clockwise)

Preceding gene: 16127471

Following gene: 16127479

Centisome position: 87.38

GC content: 67.16

Gene sequence:

>1008_bases
ATGGCTGTTCGCGTCGCCATCAACGGCTTCGGCCGCATCGGACGTCTGGTCCTGCGCTCCATCGCCGAGCATGGCCGTCG
CGATATCGAGGTCGTCGCTATCAACGACCTGGGCCCGGTCGAGACCAACGCCCACCTGCTGCGCTATGACAGCGTGCATG
GCCGCTTCCCCGGCGTCGTCACCTCGGGCGAGGACTGGATCGACGTCGGCATGGGCAAGATCAAGGTCACGGCCATCCGT
AACCCGGCCGAGCTGCCGCACAAGGACCTGGGCGTCGACATCGCGTTCGAGTGCACCGGCATCTTCACCAGCAAGGAAAA
GGCCGCCGCGCACCTGGAAGCCGGCGCCAAGCGCGTGCTGGTCAGCGCCCCGTGCGACGGCGCCGACAAGACCATCGTCT
TCAAGGTCAACGACGACACCCTGTCGGCTGACGACCTGGTTGTCTCGAACGGCTCGTGCACCACCAACTGCCTGGCCCCG
ATCGCCAAGGTCATCCACGACCTGGTCGGCATCGAGCGCGGCTACATGACGACCATCCACAGCTACACCGGCGACCAGCC
GACGCTGGATACGATGCACAAGGACCTCTACCGCGGCCGCGCGGCGGCCCTGTCGATGATCCCGACCTCGACCGGCGCGG
CCAAGGCCCTGGGCCTCGTCTTGCCGGCCCTGAAGGGCAAGCTGGACGGCTCGTCGATCCGCGTCCCGACCCCGAACGTC
TCGGTGGTCGACCTGAAGTTCGTCCCCGGTCGCGAAACCACTGTCGCCGAGCTGAACGACGCCCTGAAGGCCGCCGCCGC
CGGCCCGCTGAAGGGCGTGCTGGGCGTCACCGACGAGGCCCTGGTCTCGACGGACTTCAACCACATCGCCGAAAGCTCGA
CGGCGGCCCTGGCCCAGACCCAGGTCATCGAAGGCAAGCTGGGCCGCGTGCTCAGCTGGTACGACAACGAATGGGGCTTC
GCGACCCGCATGAGCGACACCGCGCTCGTGATGGCGAAGTTCCTGTAA

Upstream 100 bases:

>100_bases
TTCTCGGGCTTGACTTCGCGTCTTTCCCCCGCAAAACGCGCAGCAAAATAGGGAACGCCGGTCGATCACGCCTGGCGGCC
ACACATCAGGAGAATGACCC

Downstream 100 bases:

>100_bases
GGGACACTCCAACCCCCGCTCCGCAAGGCGCGGGGGTTTTGCTTGGCCGTCGCCGCGCGGCCGCCCTCGTCCTTCGACGG
GCTCAGGATGAGGGCTATTG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MAVRVAINGFGRIGRLVLRSIAEHGRRDIEVVAINDLGPVETNAHLLRYDSVHGRFPGVVTSGEDWIDVGMGKIKVTAIR
NPAELPHKDLGVDIAFECTGIFTSKEKAAAHLEAGAKRVLVSAPCDGADKTIVFKVNDDTLSADDLVVSNGSCTTNCLAP
IAKVIHDLVGIERGYMTTIHSYTGDQPTLDTMHKDLYRGRAAALSMIPTSTGAAKALGLVLPALKGKLDGSSIRVPTPNV
SVVDLKFVPGRETTVAELNDALKAAAAGPLKGVLGVTDEALVSTDFNHIAESSTAALAQTQVIEGKLGRVLSWYDNEWGF
ATRMSDTALVMAKFL

Sequences:

>Translated_335_residues
MAVRVAINGFGRIGRLVLRSIAEHGRRDIEVVAINDLGPVETNAHLLRYDSVHGRFPGVVTSGEDWIDVGMGKIKVTAIR
NPAELPHKDLGVDIAFECTGIFTSKEKAAAHLEAGAKRVLVSAPCDGADKTIVFKVNDDTLSADDLVVSNGSCTTNCLAP
IAKVIHDLVGIERGYMTTIHSYTGDQPTLDTMHKDLYRGRAAALSMIPTSTGAAKALGLVLPALKGKLDGSSIRVPTPNV
SVVDLKFVPGRETTVAELNDALKAAAAGPLKGVLGVTDEALVSTDFNHIAESSTAALAQTQVIEGKLGRVLSWYDNEWGF
ATRMSDTALVMAKFL
>Mature_334_residues
AVRVAINGFGRIGRLVLRSIAEHGRRDIEVVAINDLGPVETNAHLLRYDSVHGRFPGVVTSGEDWIDVGMGKIKVTAIRN
PAELPHKDLGVDIAFECTGIFTSKEKAAAHLEAGAKRVLVSAPCDGADKTIVFKVNDDTLSADDLVVSNGSCTTNCLAPI
AKVIHDLVGIERGYMTTIHSYTGDQPTLDTMHKDLYRGRAAALSMIPTSTGAAKALGLVLPALKGKLDGSSIRVPTPNVS
VVDLKFVPGRETTVAELNDALKAAAAGPLKGVLGVTDEALVSTDFNHIAESSTAALAQTQVIEGKLGRVLSWYDNEWGFA
TRMSDTALVMAKFL

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=332, Percent_Identity=44.2771084337349, Blast_Score=265, Evalue=5e-71,
Organism=Homo sapiens, GI7657116, Length=331, Percent_Identity=43.5045317220544, Blast_Score=258, Evalue=8e-69,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=46.1077844311377, Blast_Score=290, Evalue=6e-80,
Organism=Escherichia coli, GI1788079, Length=327, Percent_Identity=48.0122324159021, Blast_Score=286, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI17534677, Length=330, Percent_Identity=45.1515151515152, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17534679, Length=330, Percent_Identity=44.8484848484849, Blast_Score=268, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17568413, Length=329, Percent_Identity=45.5927051671732, Blast_Score=267, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI32566163, Length=329, Percent_Identity=45.5927051671732, Blast_Score=267, Evalue=5e-72,
Organism=Saccharomyces cerevisiae, GI6322468, Length=335, Percent_Identity=49.2537313432836, Blast_Score=296, Evalue=4e-81,
Organism=Saccharomyces cerevisiae, GI6322409, Length=335, Percent_Identity=47.7611940298507, Blast_Score=291, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6321631, Length=335, Percent_Identity=49.8507462686567, Blast_Score=291, Evalue=1e-79,
Organism=Drosophila melanogaster, GI85725000, Length=325, Percent_Identity=47.3846153846154, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI22023983, Length=325, Percent_Identity=47.3846153846154, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI17933600, Length=325, Percent_Identity=47.3846153846154, Blast_Score=271, Evalue=4e-73,
Organism=Drosophila melanogaster, GI18110149, Length=325, Percent_Identity=47.3846153846154, Blast_Score=271, Evalue=4e-73,
Organism=Drosophila melanogaster, GI19922412, Length=328, Percent_Identity=41.1585365853659, Blast_Score=238, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35554; Mature: 35423

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVRVAINGFGRIGRLVLRSIAEHGRRDIEVVAINDLGPVETNAHLLRYDSVHGRFPGVV
CEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCEE
TSGEDWIDVGMGKIKVTAIRNPAELPHKDLGVDIAFECTGIFTSKEKAAAHLEAGAKRVL
ECCCCEEECCCCEEEEEEECCHHHCCHHHCCEEEEEEEEEEEECHHHHHHHHHCCCCEEE
VSAPCDGADKTIVFKVNDDTLSADDLVVSNGSCTTNCLAPIAKVIHDLVGIERGYMTTIH
EECCCCCCCCEEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
SYTGDQPTLDTMHKDLYRGRAAALSMIPTSTGAAKALGLVLPALKGKLDGSSIRVPTPNV
CCCCCCCCHHHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCC
SVVDLKFVPGRETTVAELNDALKAAAAGPLKGVLGVTDEALVSTDFNHIAESSTAALAQT
EEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHCCHHHHHCCHHHHHHHH
QVIEGKLGRVLSWYDNEWGFATRMSDTALVMAKFL
HHHHHHHHHEEEEECCCCCEEEECCCHHHHHEECC
>Mature Secondary Structure 
AVRVAINGFGRIGRLVLRSIAEHGRRDIEVVAINDLGPVETNAHLLRYDSVHGRFPGVV
EEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCEE
TSGEDWIDVGMGKIKVTAIRNPAELPHKDLGVDIAFECTGIFTSKEKAAAHLEAGAKRVL
ECCCCEEECCCCEEEEEEECCHHHCCHHHCCEEEEEEEEEEEECHHHHHHHHHCCCCEEE
VSAPCDGADKTIVFKVNDDTLSADDLVVSNGSCTTNCLAPIAKVIHDLVGIERGYMTTIH
EECCCCCCCCEEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
SYTGDQPTLDTMHKDLYRGRAAALSMIPTSTGAAKALGLVLPALKGKLDGSSIRVPTPNV
CCCCCCCCHHHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCC
SVVDLKFVPGRETTVAELNDALKAAAAGPLKGVLGVTDEALVSTDFNHIAESSTAALAQT
EEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHCCHHHHHCCHHHHHHHH
QVIEGKLGRVLSWYDNEWGFATRMSDTALVMAKFL
HHHHHHHHHEEEEECCCCCEEEECCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1939098 [H]