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The map label for this gene is add

Identifier: 16127410

GI number: 16127410

Start: 3427908

End: 3428942

Strand: Direct

Name: add

Synonym: CC_3180

Alternate gene names: 16127410

Gene position: 3427908-3428942 (Clockwise)

Preceding gene: 16127408

Following gene: 16127411

Centisome position: 85.34

GC content: 66.86

Gene sequence:

>1035_bases
ATGACCGACGCTTCCTTCGCCCCATCCGCCTCCGCCGAGTTTGTCAGGGGCCTGCCCAAGGCCGAGCTGCACATGCATAT
CGAGGGCAGCCTCGAACCTGAGCTGATGTTCGAGCTCGCCCAGCGCAACGGGATCACCCTGCCCTTCGCCTCGGTCGAAG
AGATCCGCGCGGCCTACGACTTCTCGAACCTGCAGGACTTCCTGGACATCTATTACCAGGGCGCGGGCGTGCTGATCACC
GAAGCCGACTTCAAGGACCTGGCGCTCGCCTACTTCCAGCGCCTGGCGGCCGATGGCGGCGCCCACGCCGAGATCTTCTT
TGATCCGCAGACCCATACCGATCGCGGGATCGCCTTCGACACGGTGATGAACGGCCTACTGGCCGGCATGGACGAGGCCG
AGAAGACGCTGGGCGTCACCTCCAAGCTGATCCTGTGCTTCCTGCGCCACCTCTCCGAAGAGGCCGCGTTCGAGACGCTG
GAACAGGCCAAGCCATGGCTCGCCAAGCTGGCGGGCGTGGGCCTGGACAGCTCCGAGGTGGGCCACCCGCCGGCCAAGTT
CGCCCGCGTTCTTCAGGCCTCGCGGGATCTGGGCCTGAAGGTCGTCGCCCACGCCGGTGAGGAAGGCCCGCCGGCCTATG
TCTGGGAGGCCATCGACCTCGTAAAGGTCGACCGCATCGACCACGGCAACCGGGCGCTGGAGGACGAGGCCCTGACCGCG
CGCCTCGTCAAGGACGGGATCACCCTGACGGTCTGCCCGCTGTCGAACCTGAAGCTTTGCGGCGTGCCCAGCCTGGACGT
TCACCCGCTCAAGCGGATGCTGGACCTGGGCCTGAAGGCGACCGTCAACTCCGACGACCCGGCCTATTTCGGCGGCTATC
TGCTGGAGAACTACCTGGCCACCGCCGACGCCGTGGGCCTGACCCGCGATGACATCGTCACCCTGGCCAAGAACAGCTTC
GCCGGCTCGTTCCTGACCGACGCCGAGAAGGCCCAGCGGATCGCGGCGGTCGAGGCCTACGCGGCCGCTCACTGA

Upstream 100 bases:

>100_bases
GAACGGGCCCCTTGGCCAAAGTCCGGGCAGCGGCGGTTCGAGGCGCGGGCGCGCCGCGGGCGACGCTTGACCCCGTCACG
AGTGGGCCCATAACTCCCCC

Downstream 100 bases:

>100_bases
GCCGCGCGCCATGAGCCTGATCGCCGCCACCGCCTACAAGGCCGGACAGCCGGTCCGCGTGCTGGACCTGTCCTCGCCCG
AGGACCTGGTTCCGCGCGAG

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTDASFAPSASAEFVRGLPKAELHMHIEGSLEPELMFELAQRNGITLPFASVEEIRAAYDFSNLQDFLDIYYQGAGVLIT
EADFKDLALAYFQRLAADGGAHAEIFFDPQTHTDRGIAFDTVMNGLLAGMDEAEKTLGVTSKLILCFLRHLSEEAAFETL
EQAKPWLAKLAGVGLDSSEVGHPPAKFARVLQASRDLGLKVVAHAGEEGPPAYVWEAIDLVKVDRIDHGNRALEDEALTA
RLVKDGITLTVCPLSNLKLCGVPSLDVHPLKRMLDLGLKATVNSDDPAYFGGYLLENYLATADAVGLTRDDIVTLAKNSF
AGSFLTDAEKAQRIAAVEAYAAAH

Sequences:

>Translated_344_residues
MTDASFAPSASAEFVRGLPKAELHMHIEGSLEPELMFELAQRNGITLPFASVEEIRAAYDFSNLQDFLDIYYQGAGVLIT
EADFKDLALAYFQRLAADGGAHAEIFFDPQTHTDRGIAFDTVMNGLLAGMDEAEKTLGVTSKLILCFLRHLSEEAAFETL
EQAKPWLAKLAGVGLDSSEVGHPPAKFARVLQASRDLGLKVVAHAGEEGPPAYVWEAIDLVKVDRIDHGNRALEDEALTA
RLVKDGITLTVCPLSNLKLCGVPSLDVHPLKRMLDLGLKATVNSDDPAYFGGYLLENYLATADAVGLTRDDIVTLAKNSF
AGSFLTDAEKAQRIAAVEAYAAAH
>Mature_343_residues
TDASFAPSASAEFVRGLPKAELHMHIEGSLEPELMFELAQRNGITLPFASVEEIRAAYDFSNLQDFLDIYYQGAGVLITE
ADFKDLALAYFQRLAADGGAHAEIFFDPQTHTDRGIAFDTVMNGLLAGMDEAEKTLGVTSKLILCFLRHLSEEAAFETLE
QAKPWLAKLAGVGLDSSEVGHPPAKFARVLQASRDLGLKVVAHAGEEGPPAYVWEAIDLVKVDRIDHGNRALEDEALTAR
LVKDGITLTVCPLSNLKLCGVPSLDVHPLKRMLDLGLKATVNSDDPAYFGGYLLENYLATADAVGLTRDDIVTLAKNSFA
GSFLTDAEKAQRIAAVEAYAAAH

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family

Homologues:

Organism=Homo sapiens, GI47078295, Length=341, Percent_Identity=28.1524926686217, Blast_Score=121, Evalue=8e-28,
Organism=Escherichia coli, GI1787910, Length=318, Percent_Identity=29.874213836478, Blast_Score=148, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI32565969, Length=343, Percent_Identity=25.6559766763848, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17538512, Length=343, Percent_Identity=25.9475218658892, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324188, Length=338, Percent_Identity=46.1538461538462, Blast_Score=294, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24645260, Length=346, Percent_Identity=26.5895953757225, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADD_CAUCN (B8H3Z4)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002518656.1
- ProteinModelPortal:   B8H3Z4
- SMR:   B8H3Z4
- GeneID:   7330306
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_03284
- OMA:   YFGGYLN
- ProtClustDB:   PRK09358
- HAMAP:   MF_00540
- InterPro:   IPR001365
- InterPro:   IPR006330
- PANTHER:   PTHR11409
- TIGRFAMs:   TIGR01430

Pfam domain/function: PF00962 A_deaminase

EC number: =3.5.4.4

Molecular weight: Translated: 37194; Mature: 37062

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS00485 A_DEAMINASE

Important sites: ACT_SITE 207-207 BINDING 26-26 BINDING 28-28 BINDING 286-286

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDASFAPSASAEFVRGLPKAELHMHIEGSLEPELMFELAQRNGITLPFASVEEIRAAYD
CCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHH
FSNLQDFLDIYYQGAGVLITEADFKDLALAYFQRLAADGGAHAEIFFDPQTHTDRGIAFD
HHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEHH
TVMNGLLAGMDEAEKTLGVTSKLILCFLRHLSEEAAFETLEQAKPWLAKLAGVGLDSSEV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GHPPAKFARVLQASRDLGLKVVAHAGEEGPPAYVWEAIDLVKVDRIDHGNRALEDEALTA
CCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
RLVKDGITLTVCPLSNLKLCGVPSLDVHPLKRMLDLGLKATVNSDDPAYFGGYLLENYLA
HHHHCCCEEEEECCCCCEECCCCCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHH
TADAVGLTRDDIVTLAKNSFAGSFLTDAEKAQRIAAVEAYAAAH
HHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDASFAPSASAEFVRGLPKAELHMHIEGSLEPELMFELAQRNGITLPFASVEEIRAAYD
CCCCCCCCCCHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHH
FSNLQDFLDIYYQGAGVLITEADFKDLALAYFQRLAADGGAHAEIFFDPQTHTDRGIAFD
HHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEHH
TVMNGLLAGMDEAEKTLGVTSKLILCFLRHLSEEAAFETLEQAKPWLAKLAGVGLDSSEV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GHPPAKFARVLQASRDLGLKVVAHAGEEGPPAYVWEAIDLVKVDRIDHGNRALEDEALTA
CCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
RLVKDGITLTVCPLSNLKLCGVPSLDVHPLKRMLDLGLKATVNSDDPAYFGGYLLENYLA
HHHHCCCEEEEECCCCCEECCCCCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHH
TADAVGLTRDDIVTLAKNSFAGSFLTDAEKAQRIAAVEAYAAAH
HHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA