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The map label for this gene is ygjG [C]

Identifier: 16127373

GI number: 16127373

Start: 3385038

End: 3386357

Strand: Direct

Name: ygjG [C]

Synonym: CC_3143

Alternate gene names: 16127373

Gene position: 3385038-3386357 (Clockwise)

Preceding gene: 16127361

Following gene: 16127375

Centisome position: 84.27

GC content: 67.12

Gene sequence:

>1320_bases
ATGCCCGATTTCGGCGCCAACGACCTCGACGCCTTCTGGATGCCGTTCACGCCGAACCGGCGGTTCAAGCGCCATCCGCG
CATGCTCTCCTCAGCCAGCGGCATGTGGTACCGCACGCCCGAGAGCCGCGAGGTGCTGGACGCGACCTCGGGCCTCTGGT
GCGTCAACGCCGGCCATGATCGCCCCAAGATCCGCGAGGCCATCCAGAAGCAGGCGGCCGAAATGGACTACGCGCCCTGC
TTCAACATGGGCCATCCGCTAGCCTTCCAGTTCGCCTCGCGTCTGGCGCAGATCACGCCGAAGGGCCTGGACCGGATCTT
CTTCACCAATTCGGGTTCGGAGTCGGTCGACACGGCGCTGAAGATCGCCCTGGCCTATCATCGCGCGCGCGGCAAGGGGA
CCAAGACCCGGCTGATCGGGCGCGAGCGCGGCTATCACGGCGTCGGCTTTGGCGGCATCTCGGTGGGGGGCATTCCCAAG
AACCGGATGTATTTCGGCAGCTTGCTGACCGGCGTCGACCACCTGCCCCACACCCATGGCCTGCCGGGCAACACCTGCGC
TAAGGGCCAACCCGAGAACGGCGCGCACCTGGCCGATGATCTGGAACGGATCGTCGCCTTGCACGACGCCTCCAACATCG
CCGCCGTCATCGTCGAGCCGGTCGCCGGTTCAACGGGCGTGCTGATTCCGCCGAAGGGTTATCTGGAACGCCTGCGAGCG
ATCTGCGACAAGCACGACATCCTGCTGATCTTCGACGAGGTGATCACCGGCTTTGGACGGGTCGGCGCGCCGTTCGCCGC
CGAACGCTTCGGCGTCACGCCCGACCTGATCTGCATGGCCAAGGGCCTGACCAACGCCGCCGTGCCCTGCGGCGCCGTGG
CGGCCTCGGGTAAGATCTATGATGCGATGATGGACGGCGCCGACGCGCCCATCGAGCTCTTCCACGGCTACACCTATTCG
GCCCACCCGCTGGCCTGCGCCGCCGGTCTCGCGACGCTGGAGACCTATCGCGAGGACGACCTCTTCGCGCGCGCCGCCGG
GCTGGAGGGCTATTGGCAGGACGCGATGCACAGCCTGGCCGACGCCCGCCACGTCGTGGATGTCCGCAATCTCGGGCTCG
TCGCCGGGATCGAGCTTGAACCCCGTCCCGGCGCCCCCACCGCGCGGGCGATGGAGGTCTTCGAGACCTGCTTCGACGAG
GGTCTGCTGATCCGTGTGACCGGCGACATCATCGCCCTGTCGCCGCCGCTGATCCTGGAGAAGGATCACATCGACCGGAT
GGTCGAGACGATCCGCAGGGTGCTGGGTCAGGTCGATTAG

Upstream 100 bases:

>100_bases
GCGAGAGGCCGGCGGGTCTTCATGCATGGGTTTCCAAGAAGGCCTTGCCAGTTGGCCCTGAATTGCGATCACAATGCAAG
CGCTCGCAAGGATGCTGCCC

Downstream 100 bases:

>100_bases
ACCAGCTTAGCTCCAGAAGGCGCCGCCCTAGGCGGTCGCGTCCGGGAAGCCGCGCCACTCGACCCATTCGCCGTAGGGAT
GGCAGATGGCGAGGATCGTC

Product: beta alanine--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MPDFGANDLDAFWMPFTPNRRFKRHPRMLSSASGMWYRTPESREVLDATSGLWCVNAGHDRPKIREAIQKQAAEMDYAPC
FNMGHPLAFQFASRLAQITPKGLDRIFFTNSGSESVDTALKIALAYHRARGKGTKTRLIGRERGYHGVGFGGISVGGIPK
NRMYFGSLLTGVDHLPHTHGLPGNTCAKGQPENGAHLADDLERIVALHDASNIAAVIVEPVAGSTGVLIPPKGYLERLRA
ICDKHDILLIFDEVITGFGRVGAPFAAERFGVTPDLICMAKGLTNAAVPCGAVAASGKIYDAMMDGADAPIELFHGYTYS
AHPLACAAGLATLETYREDDLFARAAGLEGYWQDAMHSLADARHVVDVRNLGLVAGIELEPRPGAPTARAMEVFETCFDE
GLLIRVTGDIIALSPPLILEKDHIDRMVETIRRVLGQVD

Sequences:

>Translated_439_residues
MPDFGANDLDAFWMPFTPNRRFKRHPRMLSSASGMWYRTPESREVLDATSGLWCVNAGHDRPKIREAIQKQAAEMDYAPC
FNMGHPLAFQFASRLAQITPKGLDRIFFTNSGSESVDTALKIALAYHRARGKGTKTRLIGRERGYHGVGFGGISVGGIPK
NRMYFGSLLTGVDHLPHTHGLPGNTCAKGQPENGAHLADDLERIVALHDASNIAAVIVEPVAGSTGVLIPPKGYLERLRA
ICDKHDILLIFDEVITGFGRVGAPFAAERFGVTPDLICMAKGLTNAAVPCGAVAASGKIYDAMMDGADAPIELFHGYTYS
AHPLACAAGLATLETYREDDLFARAAGLEGYWQDAMHSLADARHVVDVRNLGLVAGIELEPRPGAPTARAMEVFETCFDE
GLLIRVTGDIIALSPPLILEKDHIDRMVETIRRVLGQVD
>Mature_438_residues
PDFGANDLDAFWMPFTPNRRFKRHPRMLSSASGMWYRTPESREVLDATSGLWCVNAGHDRPKIREAIQKQAAEMDYAPCF
NMGHPLAFQFASRLAQITPKGLDRIFFTNSGSESVDTALKIALAYHRARGKGTKTRLIGRERGYHGVGFGGISVGGIPKN
RMYFGSLLTGVDHLPHTHGLPGNTCAKGQPENGAHLADDLERIVALHDASNIAAVIVEPVAGSTGVLIPPKGYLERLRAI
CDKHDILLIFDEVITGFGRVGAPFAAERFGVTPDLICMAKGLTNAAVPCGAVAASGKIYDAMMDGADAPIELFHGYTYSA
HPLACAAGLATLETYREDDLFARAAGLEGYWQDAMHSLADARHVVDVRNLGLVAGIELEPRPGAPTARAMEVFETCFDEG
LLIRVTGDIIALSPPLILEKDHIDRMVETIRRVLGQVD

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=416, Percent_Identity=27.6442307692308, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI13994255, Length=442, Percent_Identity=28.0542986425339, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI284507298, Length=332, Percent_Identity=29.5180722891566, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI37574042, Length=401, Percent_Identity=26.9326683291771, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI226442709, Length=391, Percent_Identity=26.8542199488491, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI226442705, Length=364, Percent_Identity=26.9230769230769, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI24119277, Length=430, Percent_Identity=24.4186046511628, Blast_Score=106, Evalue=4e-23,
Organism=Escherichia coli, GI145693181, Length=401, Percent_Identity=32.9177057356608, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1786991, Length=433, Percent_Identity=30.715935334873, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1789759, Length=410, Percent_Identity=28.5365853658537, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1789016, Length=435, Percent_Identity=28.735632183908, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI1788044, Length=413, Percent_Identity=27.6029055690073, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1787560, Length=437, Percent_Identity=28.1464530892449, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1786349, Length=326, Percent_Identity=28.2208588957055, Blast_Score=101, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI32564660, Length=441, Percent_Identity=28.7981859410431, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI25144271, Length=423, Percent_Identity=26.0047281323877, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71992977, Length=446, Percent_Identity=27.8026905829596, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI25144274, Length=308, Percent_Identity=26.9480519480519, Blast_Score=114, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6323470, Length=422, Percent_Identity=29.1469194312796, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6324386, Length=439, Percent_Identity=26.4236902050114, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324432, Length=414, Percent_Identity=24.8792270531401, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI161085790, Length=448, Percent_Identity=28.5714285714286, Blast_Score=151, Evalue=9e-37,
Organism=Drosophila melanogaster, GI21357415, Length=417, Percent_Identity=25.6594724220624, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI28574759, Length=432, Percent_Identity=28.7037037037037, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI21356575, Length=430, Percent_Identity=26.7441860465116, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 47629; Mature: 47498

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDFGANDLDAFWMPFTPNRRFKRHPRMLSSASGMWYRTPESREVLDATSGLWCVNAGHD
CCCCCCCCCCCEECCCCCCCHHHHCCHHHHHCCCCEEECCCCHHHHHHCCCEEEEECCCC
RPKIREAIQKQAAEMDYAPCFNMGHPLAFQFASRLAQITPKGLDRIFFTNSGSESVDTAL
CHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHH
KIALAYHRARGKGTKTRLIGRERGYHGVGFGGISVGGIPKNRMYFGSLLTGVDHLPHTHG
HHHHHHHHHCCCCCHHEEEECCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCC
LPGNTCAKGQPENGAHLADDLERIVALHDASNIAAVIVEPVAGSTGVLIPPKGYLERLRA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEECCHHHHHHHHH
ICDKHDILLIFDEVITGFGRVGAPFAAERFGVTPDLICMAKGLTNAAVPCGAVAASGKIY
HHCCCCEEEEEHHHHHHCCCCCCCHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHCCCCHH
DAMMDGADAPIELFHGYTYSAHPLACAAGLATLETYREDDLFARAAGLEGYWQDAMHSLA
HHHHCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
DARHVVDVRNLGLVAGIELEPRPGAPTARAMEVFETCFDEGLLIRVTGDIIALSPPLILE
HHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCEEEECCCCEEC
KDHIDRMVETIRRVLGQVD
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PDFGANDLDAFWMPFTPNRRFKRHPRMLSSASGMWYRTPESREVLDATSGLWCVNAGHD
CCCCCCCCCCEECCCCCCCHHHHCCHHHHHCCCCEEECCCCHHHHHHCCCEEEEECCCC
RPKIREAIQKQAAEMDYAPCFNMGHPLAFQFASRLAQITPKGLDRIFFTNSGSESVDTAL
CHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHH
KIALAYHRARGKGTKTRLIGRERGYHGVGFGGISVGGIPKNRMYFGSLLTGVDHLPHTHG
HHHHHHHHHCCCCCHHEEEECCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCC
LPGNTCAKGQPENGAHLADDLERIVALHDASNIAAVIVEPVAGSTGVLIPPKGYLERLRA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEECCHHHHHHHHH
ICDKHDILLIFDEVITGFGRVGAPFAAERFGVTPDLICMAKGLTNAAVPCGAVAASGKIY
HHCCCCEEEEEHHHHHHCCCCCCCHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHCCCCHH
DAMMDGADAPIELFHGYTYSAHPLACAAGLATLETYREDDLFARAAGLEGYWQDAMHSLA
HHHHCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
DARHVVDVRNLGLVAGIELEPRPGAPTARAMEVFETCFDEGLLIRVTGDIIALSPPLILE
HHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCEEEECCCCEEC
KDHIDRMVETIRRVLGQVD
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]