Click here to switch to the map view.

The map label for this gene is ltaE [H]

Identifier: 16127323

GI number: 16127323

Start: 3324396

End: 3325427

Strand: Direct

Name: ltaE [H]

Synonym: CC_3093

Alternate gene names: 16127323

Gene position: 3324396-3325427 (Clockwise)

Preceding gene: 16127322

Following gene: 16127327

Centisome position: 82.76

GC content: 70.83

Gene sequence:

>1032_bases
ATGACCCAGACCGCGCCCCGCTACGATTTCGCCTCCGACAACGTCGCCGGCGCCATGCCCGAGGTGATGGAGGCGTTGAT
CGCGGCCAATGCGGGGACGGCCTCGGGCTACGGGACCGACCATGTCAGCCGTGCCGCCGCCGATCGCATCCGCGCGGCGC
TGGACGCCGACGCGCAGGTGCGGTTCACAGCCTCGGGCACGGCGGCCAACGCCTTCGCCCTGACCCTGCTGGCCCAGCCG
CACGAGGCGGTGCTGGCCCACGAGCACGCCCACATCTGCACGGACGAGACCGGCGCGCCCGGCTTCTTTGGCCAGGGCGT
CGGCCTGATCGGCTTGCCGGGCGCATCGGGCAAGATGGAGTTGGCGGCCCTGGAGGCGGCGCTGGCCCAGCCGGACGTCT
CGTACCGCCAGCCGGCGGCGGCCTTGTCGCTGACCACCGCCACCGAGTACGGCACGGTCTATTCGGAAGACCACCTGCGG
GCCCTGATCGCGCCGGTGAAGGCCAAGGGCTATGGCGTCCACCTGGACGGCGCGCGGCTGGCCAATGCGGTCGCGGGGGG
CTTTGACCTGAAAAGCATCGCCAAGATGGGCGTCGACATCCTGGTGATGGGCGGCACCAAGGCCGGCTCGACGCCCACCG
AGGCCGTGGTGTTCCTGAACCCCGACCACGCCAAACGCCTGGACGCGCGCCTCAAGCACGCCGGCCAGCTGATCTCGAAG
GGACGCTTCCTGGCCGCGCCGTGGCTGGGCCTGCTGGGCGAGAACGGTCAGACCGCCCCCTGGGCCGCCCGCGCCGCCCA
CGCCAACGCCATGGCGCAGAAGCTGGCCGCGCTGATGCCCGTCCCGATCAAGCACCCGGTCGAGGCCAACGGCATCTTCG
TCGAGATGGACGAACTTGCCCTGGAACGCCTGCGCGGCGAAGGCTGGTTCGTCTATCGCTTCCTGGACGGCACGGTGCGC
TTCATGTGCTCGTGGGCCACGACGCCCGAGATGGTCGAGGATCTGGGCGCGGCGCTGAAGCGAGTGGCTTAG

Upstream 100 bases:

>100_bases
CGCCCTACAAGGCGGGCGTGTCGGTCTGGACGTGCGAGGCGCAGCCGTGGCATCCGATCGACCCGGCCGCTCCGGCCTTT
GCGAAAAACCCCTCAGGTTG

Downstream 100 bases:

>100_bases
CGCGCCGCCTCCGTCACGCGGCTTGGCCGCGCGACCCCTCGCCCGTACGCTCCGCTACGGGTGAGGAGGGCGCCGTCCGA
ACCTCCTGCCCCGCTTGCGG

Product: threonine aldolase, low-specificity

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MTQTAPRYDFASDNVAGAMPEVMEALIAANAGTASGYGTDHVSRAAADRIRAALDADAQVRFTASGTAANAFALTLLAQP
HEAVLAHEHAHICTDETGAPGFFGQGVGLIGLPGASGKMELAALEAALAQPDVSYRQPAAALSLTTATEYGTVYSEDHLR
ALIAPVKAKGYGVHLDGARLANAVAGGFDLKSIAKMGVDILVMGGTKAGSTPTEAVVFLNPDHAKRLDARLKHAGQLISK
GRFLAAPWLGLLGENGQTAPWAARAAHANAMAQKLAALMPVPIKHPVEANGIFVEMDELALERLRGEGWFVYRFLDGTVR
FMCSWATTPEMVEDLGAALKRVA

Sequences:

>Translated_343_residues
MTQTAPRYDFASDNVAGAMPEVMEALIAANAGTASGYGTDHVSRAAADRIRAALDADAQVRFTASGTAANAFALTLLAQP
HEAVLAHEHAHICTDETGAPGFFGQGVGLIGLPGASGKMELAALEAALAQPDVSYRQPAAALSLTTATEYGTVYSEDHLR
ALIAPVKAKGYGVHLDGARLANAVAGGFDLKSIAKMGVDILVMGGTKAGSTPTEAVVFLNPDHAKRLDARLKHAGQLISK
GRFLAAPWLGLLGENGQTAPWAARAAHANAMAQKLAALMPVPIKHPVEANGIFVEMDELALERLRGEGWFVYRFLDGTVR
FMCSWATTPEMVEDLGAALKRVA
>Mature_342_residues
TQTAPRYDFASDNVAGAMPEVMEALIAANAGTASGYGTDHVSRAAADRIRAALDADAQVRFTASGTAANAFALTLLAQPH
EAVLAHEHAHICTDETGAPGFFGQGVGLIGLPGASGKMELAALEAALAQPDVSYRQPAAALSLTTATEYGTVYSEDHLRA
LIAPVKAKGYGVHLDGARLANAVAGGFDLKSIAKMGVDILVMGGTKAGSTPTEAVVFLNPDHAKRLDARLKHAGQLISKG
RFLAAPWLGLLGENGQTAPWAARAAHANAMAQKLAALMPVPIKHPVEANGIFVEMDELALERLRGEGWFVYRFLDGTVRF
MCSWATTPEMVEDLGAALKRVA

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320789, Length=302, Percent_Identity=25.4966887417219, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 35908; Mature: 35777

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTAPRYDFASDNVAGAMPEVMEALIAANAGTASGYGTDHVSRAAADRIRAALDADAQV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
RFTASGTAANAFALTLLAQPHEAVLAHEHAHICTDETGAPGFFGQGVGLIGLPGASGKME
EEEECCCCCCCEEEEEECCCHHHHHHHCCCEEECCCCCCCCCCCCCCCEEECCCCCCCCH
LAALEAALAQPDVSYRQPAAALSLTTATEYGTVYSEDHLRALIAPVKAKGYGVHLDGARL
HHHHHHHHCCCCCCCCCCCHHEEEEEHHHCCCEECHHHHHHHHHHHCCCCEEEEECHHHH
ANAVAGGFDLKSIAKMGVDILVMGGTKAGSTPTEAVVFLNPDHAKRLDARLKHAGQLISK
HHHHHCCCCHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHC
GRFLAAPWLGLLGENGQTAPWAARAAHANAMAQKLAALMPVPIKHPVEANGIFVEMDELA
CCEEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHH
LERLRGEGWFVYRFLDGTVRFMCSWATTPEMVEDLGAALKRVA
HHHHCCCCEEEEEEECCEEEEEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQTAPRYDFASDNVAGAMPEVMEALIAANAGTASGYGTDHVSRAAADRIRAALDADAQV
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
RFTASGTAANAFALTLLAQPHEAVLAHEHAHICTDETGAPGFFGQGVGLIGLPGASGKME
EEEECCCCCCCEEEEEECCCHHHHHHHCCCEEECCCCCCCCCCCCCCCEEECCCCCCCCH
LAALEAALAQPDVSYRQPAAALSLTTATEYGTVYSEDHLRALIAPVKAKGYGVHLDGARL
HHHHHHHHCCCCCCCCCCCHHEEEEEHHHCCCEECHHHHHHHHHHHCCCCEEEEECHHHH
ANAVAGGFDLKSIAKMGVDILVMGGTKAGSTPTEAVVFLNPDHAKRLDARLKHAGQLISK
HHHHHCCCCHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHC
GRFLAAPWLGLLGENGQTAPWAARAAHANAMAQKLAALMPVPIKHPVEANGIFVEMDELA
CCEEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHH
LERLRGEGWFVYRFLDGTVRFMCSWATTPEMVEDLGAALKRVA
HHHHCCCCEEEEEEECCEEEEEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]