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The map label for this gene is cdd [H]

Identifier: 16127242

GI number: 16127242

Start: 3231043

End: 3231465

Strand: Direct

Name: cdd [H]

Synonym: CC_3012

Alternate gene names: 16127242

Gene position: 3231043-3231465 (Clockwise)

Preceding gene: 16127241

Following gene: 16127244

Centisome position: 80.44

GC content: 69.74

Gene sequence:

>423_bases
ATGAACGCCGACACCGTTTCTAAAGCTGTTGAGGACGAGATCGCCGCCGCGCTGCCGCCGCTGCTGTCGCGAGCCTATGC
CCGCTATTCGAAGTTCACGGTGGCGGCGGCGGTCATCGACGAGACCGGGGCGGTCCACTACGGCGTCAATGTCGAGAACG
CCGCCTATCCGCAGGGCACCTGCGCCGAGCAGACGGCGATCGGGGCGATGATCACGGCCGCCGGCGCGCGCCGCATCGAC
AAGGTGCTGATCGCCGCCGGCTCCGGCGCCGTAGTTCAGCCCTGCGGTGGTTGCCGCCAGCGCATCGCCGAGTTCGCCGG
CGAGGCCTGCGAGATCATCTCGGTGCAGGGTGGCAAGCCCACCGAGCGGGTGGCGTTCTGGGACCTGCTGCCGCGCTCGT
TCGGCCCGCGCGACCTGGACTGA

Upstream 100 bases:

>100_bases
TAAATCAAACACTTAGAGCGTGACTCGCGCCGAAACCGGTTCCCACTTTCGGCGTCACGCTCTGACCCCGGCGCGATCTT
GCCGGAGGGCAGGAACACCG

Downstream 100 bases:

>100_bases
GCCCCGCCAACGCCTCGAACACGCCGCCGCCGCCCGTCGGCGGCGGCTTTTTCGCGCCCTATCGGCAAAGAAAAAGGGGC
GGTCCGAAGACCGCCCCTTT

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MNADTVSKAVEDEIAAALPPLLSRAYARYSKFTVAAAVIDETGAVHYGVNVENAAYPQGTCAEQTAIGAMITAAGARRID
KVLIAAGSGAVVQPCGGCRQRIAEFAGEACEIISVQGGKPTERVAFWDLLPRSFGPRDLD

Sequences:

>Translated_140_residues
MNADTVSKAVEDEIAAALPPLLSRAYARYSKFTVAAAVIDETGAVHYGVNVENAAYPQGTCAEQTAIGAMITAAGARRID
KVLIAAGSGAVVQPCGGCRQRIAEFAGEACEIISVQGGKPTERVAFWDLLPRSFGPRDLD
>Mature_140_residues
MNADTVSKAVEDEIAAALPPLLSRAYARYSKFTVAAAVIDETGAVHYGVNVENAAYPQGTCAEQTAIGAMITAAGARRID
KVLIAAGSGAVVQPCGGCRQRIAEFAGEACEIISVQGGKPTERVAFWDLLPRSFGPRDLD

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=117, Percent_Identity=37.6068376068376, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551074, Length=119, Percent_Identity=35.2941176470588, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17540514, Length=141, Percent_Identity=31.2056737588652, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6323274, Length=119, Percent_Identity=33.6134453781513, Blast_Score=71, Evalue=7e-14,
Organism=Drosophila melanogaster, GI19920920, Length=145, Percent_Identity=31.7241379310345, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14627; Mature: 14627

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNADTVSKAVEDEIAAALPPLLSRAYARYSKFTVAAAVIDETGAVHYGVNVENAAYPQGT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCC
CAEQTAIGAMITAAGARRIDKVLIAAGSGAVVQPCGGCRQRIAEFAGEACEIISVQGGKP
CHHHHHHHHHHHHHHHHHHHHHEEECCCCCEECCCHHHHHHHHHHCCCCEEEEEECCCCC
TERVAFWDLLPRSFGPRDLD
HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNADTVSKAVEDEIAAALPPLLSRAYARYSKFTVAAAVIDETGAVHYGVNVENAAYPQGT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCC
CAEQTAIGAMITAAGARRIDKVLIAAGSGAVVQPCGGCRQRIAEFAGEACEIISVQGGKP
CHHHHHHHHHHHHHHHHHHHHHEEECCCCCEECCCHHHHHHHHHHCCCCEEEEEECCCCC
TERVAFWDLLPRSFGPRDLD
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]