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The map label for this gene is 16127139

Identifier: 16127139

GI number: 16127139

Start: 3130503

End: 3132173

Strand: Direct

Name: 16127139

Synonym: CC_2909

Alternate gene names: NA

Gene position: 3130503-3132173 (Clockwise)

Preceding gene: 16127137

Following gene: 16127140

Centisome position: 77.93

GC content: 70.62

Gene sequence:

>1671_bases
ATGCCAGGGCTCGAAACGGCGGAACACGGCCTGCGCCGGCGCGTCAGCTCGGTGCGTGGCCGCCTGGTGCTTCTGACCGT
CAGCCTGTTGGTTCCAGCCCTGCTGGCGATGGGCTTTCTGCTGGCCAGCGCCGATCGCGAGTCGCGCGGACGCCTTTATC
AGCAGCTTCTGACCACCGCGCGCGCGCTGAACGGCGCCGTCGACCGCCAGGCCGCCACCGGGATCTCGGTGGCCGAGACC
CTGGCCACCGACGAGGCCCTGCTGGCCGGCGACTGGGCTGGGTTCCACGCCCGGGCGCGACGGGCCATGGAGCGGCGCAC
AGGCTGGATCGTGGTGGCCGACGCCAACGGCCAGCAGGTGCTCAACACCCGCGTTCCCTATGGCCGCCCCCTGCCCCGCA
TCCAGCGCACGCCTGAAGAAACCAAGGCTTTTCTGGCGGGGCGCAGCAAGGTCTCGGACCTGCTGGCCGGCCCTGTCGCC
GGCACGCCGGTGATCACGGTCGGCACGCCGATCACCGTCAAGGGCCGATTCTATGTGCTGTCCTATGTGGTGGACGCCGC
GTCGTTCACCTCGGTGTTCCGCCAGCAGCGGGTGCCGGACACCTGGGTGGCGACCCTGCTGGACAACCGGCAGCGGGTGA
TCGCCCGCTCGCGGCTCAATGAGAAGTTCACCGGCGCCCAGGCCTCGGCCGACATGACCGAGAATCTCCGCCACTCCACC
GAGGGGGTGAACAGGAGCATCTCCCTGGAAGGCGTGCCGACCAGGGTCGCCTATACCCGCTCGCCGCAGACGGGCTGGAC
CCTGGTGGTGGCCATTCCGCGCAAGGAGCTGGCCAGCACCGTCAATCGCTCGGTCGCGGTCGGCACCGGGATCTTCCTGC
TGCTCCTGGTGCTGGGCTTGTGGCTGGCGCTGGTCTATTCGCGGCGGATCAACCGCGACATGCGGCGGCTGGTGCGCGAC
GCCTCGGCGATCGGGCGCGGCGAGTCGCTGCAGCCGGCGCCGCGCGACAGCCTGGAGGAGATCGCCGCCGTTCACGCCGC
CCTGCTGACCGCCTCGGAGGAGCTGAAGGCCCGCGAGGAACGCCAGGGCGTGATGATCAACGAGCTGAACCACCGGGTGA
AGAACACGCTGGCCACGGTGCAGGCCCTGGCCCGCCAGACCTTCGCCAAGGTCGACGGCGCGCCGCTGGGCGTCTTTACC
GATCGCCTGATCGCCCTGTCCGGCGCCCATGATCTCCTGACCCGCACCGGCTGGCGCGAGGCCGACATGGCCGCGCTGAT
AGAGGCCAGCCTCGGCGCGCACGGCGATCGCGTGGATCGCGAAGGTCCCACCGTGGCCCTGGCCCCGCATACGGCCGTCG
GCCTGTCGATGGTGTTCCACGAACTGGCCACCAACAGCGCCAAGTACGGCGCGCTGTCGGCGCCGGGCGGGCGCGTGGCC
CTGACCTGGCGACGCGATCCGGTCAGCGACACCCTGTTCTTCACCTGGCGGGACGTCGGCGGCCCGCAGGTCATCCCGCC
CGCCTCGCTGGGCTTTGGCACCCGCCTGATCGAAAGCTCCATCCGGCGCGAGCAGAAGGGTCAGGCCCGTTTCGACTTCC
TGCCCGACGGCCTGGTGTTCGAGGCCTCGCTGCCGCTGCCCGAGGCGGTGCGCTGGAGCAATCCGCTCTGA

Upstream 100 bases:

>100_bases
TAACCACGCTGGGGGATTTTTCGGACGCGGGACGCGACTCGCTCCGATATACAAAACCGGAGAGCGGCACGGCGCTCTTG
TCGATGCGGGCGCGCCAGGC

Downstream 100 bases:

>100_bases
TGGCCCCGCCGCCGGCCGATACGGCCGCCGCCTTGGCGCGCTTCATCGATCAGGAACGCCTGCCGCCCGCCTTCGCCGCC
CTGGCCCAGCGCCTGCACCT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 556; Mature: 555

Protein sequence:

>556_residues
MPGLETAEHGLRRRVSSVRGRLVLLTVSLLVPALLAMGFLLASADRESRGRLYQQLLTTARALNGAVDRQAATGISVAET
LATDEALLAGDWAGFHARARRAMERRTGWIVVADANGQQVLNTRVPYGRPLPRIQRTPEETKAFLAGRSKVSDLLAGPVA
GTPVITVGTPITVKGRFYVLSYVVDAASFTSVFRQQRVPDTWVATLLDNRQRVIARSRLNEKFTGAQASADMTENLRHST
EGVNRSISLEGVPTRVAYTRSPQTGWTLVVAIPRKELASTVNRSVAVGTGIFLLLLVLGLWLALVYSRRINRDMRRLVRD
ASAIGRGESLQPAPRDSLEEIAAVHAALLTASEELKAREERQGVMINELNHRVKNTLATVQALARQTFAKVDGAPLGVFT
DRLIALSGAHDLLTRTGWREADMAALIEASLGAHGDRVDREGPTVALAPHTAVGLSMVFHELATNSAKYGALSAPGGRVA
LTWRRDPVSDTLFFTWRDVGGPQVIPPASLGFGTRLIESSIRREQKGQARFDFLPDGLVFEASLPLPEAVRWSNPL

Sequences:

>Translated_556_residues
MPGLETAEHGLRRRVSSVRGRLVLLTVSLLVPALLAMGFLLASADRESRGRLYQQLLTTARALNGAVDRQAATGISVAET
LATDEALLAGDWAGFHARARRAMERRTGWIVVADANGQQVLNTRVPYGRPLPRIQRTPEETKAFLAGRSKVSDLLAGPVA
GTPVITVGTPITVKGRFYVLSYVVDAASFTSVFRQQRVPDTWVATLLDNRQRVIARSRLNEKFTGAQASADMTENLRHST
EGVNRSISLEGVPTRVAYTRSPQTGWTLVVAIPRKELASTVNRSVAVGTGIFLLLLVLGLWLALVYSRRINRDMRRLVRD
ASAIGRGESLQPAPRDSLEEIAAVHAALLTASEELKAREERQGVMINELNHRVKNTLATVQALARQTFAKVDGAPLGVFT
DRLIALSGAHDLLTRTGWREADMAALIEASLGAHGDRVDREGPTVALAPHTAVGLSMVFHELATNSAKYGALSAPGGRVA
LTWRRDPVSDTLFFTWRDVGGPQVIPPASLGFGTRLIESSIRREQKGQARFDFLPDGLVFEASLPLPEAVRWSNPL
>Mature_555_residues
PGLETAEHGLRRRVSSVRGRLVLLTVSLLVPALLAMGFLLASADRESRGRLYQQLLTTARALNGAVDRQAATGISVAETL
ATDEALLAGDWAGFHARARRAMERRTGWIVVADANGQQVLNTRVPYGRPLPRIQRTPEETKAFLAGRSKVSDLLAGPVAG
TPVITVGTPITVKGRFYVLSYVVDAASFTSVFRQQRVPDTWVATLLDNRQRVIARSRLNEKFTGAQASADMTENLRHSTE
GVNRSISLEGVPTRVAYTRSPQTGWTLVVAIPRKELASTVNRSVAVGTGIFLLLLVLGLWLALVYSRRINRDMRRLVRDA
SAIGRGESLQPAPRDSLEEIAAVHAALLTASEELKAREERQGVMINELNHRVKNTLATVQALARQTFAKVDGAPLGVFTD
RLIALSGAHDLLTRTGWREADMAALIEASLGAHGDRVDREGPTVALAPHTAVGLSMVFHELATNSAKYGALSAPGGRVAL
TWRRDPVSDTLFFTWRDVGGPQVIPPASLGFGTRLIESSIRREQKGQARFDFLPDGLVFEASLPLPEAVRWSNPL

Specific function: Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG3920

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR011102 [H]

Pfam domain/function: PF07536 HWE_HK; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60448; Mature: 60317

Theoretical pI: Translated: 11.08; Mature: 11.08

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGLETAEHGLRRRVSSVRGRLVLLTVSLLVPALLAMGFLLASADRESRGRLYQQLLTTA
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RALNGAVDRQAATGISVAETLATDEALLAGDWAGFHARARRAMERRTGWIVVADANGQQV
HHHHHHHHHHHHCCCHHHHHHHCCCHHEECCCHHHHHHHHHHHHHCCCEEEEECCCCCCH
LNTRVPYGRPLPRIQRTPEETKAFLAGRSKVSDLLAGPVAGTPVITVGTPITVKGRFYVL
HHCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEECCHHHHH
SYVVDAASFTSVFRQQRVPDTWVATLLDNRQRVIARSRLNEKFTGAQASADMTENLRHST
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHH
EGVNRSISLEGVPTRVAYTRSPQTGWTLVVAIPRKELASTVNRSVAVGTGIFLLLLVLGL
HCCCCEEEECCCCCEEEEECCCCCCCEEEEEECHHHHHHHHHCHHHHHHHHHHHHHHHHH
WLALVYSRRINRDMRRLVRDASAIGRGESLQPAPRDSLEEIAAVHAALLTASEELKAREE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RQGVMINELNHRVKNTLATVQALARQTFAKVDGAPLGVFTDRLIALSGAHDLLTRTGWRE
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHCCCCH
ADMAALIEASLGAHGDRVDREGPTVALAPHTAVGLSMVFHELATNSAKYGALSAPGGRVA
HHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
LTWRRDPVSDTLFFTWRDVGGPQVIPPASLGFGTRLIESSIRREQKGQARFDFLPDGLVF
EEECCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
EASLPLPEAVRWSNPL
EECCCCCHHCCCCCCC
>Mature Secondary Structure 
PGLETAEHGLRRRVSSVRGRLVLLTVSLLVPALLAMGFLLASADRESRGRLYQQLLTTA
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RALNGAVDRQAATGISVAETLATDEALLAGDWAGFHARARRAMERRTGWIVVADANGQQV
HHHHHHHHHHHHCCCHHHHHHHCCCHHEECCCHHHHHHHHHHHHHCCCEEEEECCCCCCH
LNTRVPYGRPLPRIQRTPEETKAFLAGRSKVSDLLAGPVAGTPVITVGTPITVKGRFYVL
HHCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEECCHHHHH
SYVVDAASFTSVFRQQRVPDTWVATLLDNRQRVIARSRLNEKFTGAQASADMTENLRHST
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHH
EGVNRSISLEGVPTRVAYTRSPQTGWTLVVAIPRKELASTVNRSVAVGTGIFLLLLVLGL
HCCCCEEEECCCCCEEEEECCCCCCCEEEEEECHHHHHHHHHCHHHHHHHHHHHHHHHHH
WLALVYSRRINRDMRRLVRDASAIGRGESLQPAPRDSLEEIAAVHAALLTASEELKAREE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RQGVMINELNHRVKNTLATVQALARQTFAKVDGAPLGVFTDRLIALSGAHDLLTRTGWRE
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHCCCCH
ADMAALIEASLGAHGDRVDREGPTVALAPHTAVGLSMVFHELATNSAKYGALSAPGGRVA
HHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
LTWRRDPVSDTLFFTWRDVGGPQVIPPASLGFGTRLIESSIRREQKGQARFDFLPDGLVF
EEECCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
EASLPLPEAVRWSNPL
EECCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA