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The map label for this gene is ybdR [H]

Identifier: 16127069

GI number: 16127069

Start: 3063660

End: 3064700

Strand: Direct

Name: ybdR [H]

Synonym: CC_2837

Alternate gene names: 16127069

Gene position: 3063660-3064700 (Clockwise)

Preceding gene: 16127068

Following gene: 16127072

Centisome position: 76.27

GC content: 72.05

Gene sequence:

>1041_bases
ATGAAAGCCCTGCGCTATCACGGCGCCCGCGACGTCCGGTACGAGAGCATGGACGATCCCACGCCCCAGTCGGACCGCGA
CGCGATCGTCCAGGTCACCGCCTGCTCGATCTGCGGCTCGGACCTGCACATCTATCACGGCCATGGCTTCTCGGAGGACC
TCGGGTTCTGCGTCGGCCACGAGGCGGTCGGCGAGGTGGTCGAGGTCGGGCGCGGCGTCCAGCGGCTGAAGGTCGGCGAC
AAGGTCATGCTGCCGGCCGCCGTAGGCTGCGGGCGTTGCCGCTCGTGCCTGTCGGGCGTGATCCAGACCTGCGAGAACGG
CCAAGGCGCCTGCTATGGCCTGTCGGCGCGGCTGCAGGGCTCGCAGGCGGAAGCCGTGCGCGTGCCGGCCGCCGACATGA
ACGCCGTGCCCGTGCCCGACGGCGTCTCGATGGACCAGGCGCTGATGATGACCGACGCCCTGGCCACGGCCTGGTTCGGG
GCTCGCAACGCCGAGGTGCGGCCGGGCGCCAGCGTGGCGGTGATCGGCCTTGGCCCCATCGGCCTGATGGCGGTCGAGAG
CGCCTATGTGATGGGCGCGCACGTCGTCTACGCCATCGATCCCCTGCCCGCTCGCCGAGCTTTGGCGGAGGAGGCCGGCG
CCATCGCCCTGCATCCCGACGAGGCCCTGGCGCGCGTGCGCGAGGACACCAAGGGGCGCGGCCTGGACTGCGTGATCGAG
GCGGTCGGCGGCGAGGCCACGGTGGATGCGGCCCTGCGCCTGGTGCGGCCGCGCGGCGTGGTGTCGGTGATCGGGGTGCA
GCAGGCCAAGCGCTTCGCGTTCCCGCTAGAGCGCGCCTTCGGGGCGGGCCTGACCTTCCGGGTGGGAACCTGCTCGGTGC
CCGAGGAACTGCCGGCGCTGTTTCCGCTGGTGCGGTCGGGACGCCTGCGGCCCGAGAAATACATCAGCCACCGCCTGCCG
CTCAGCGACGGGCCTGAGGCCTACCGCCTGTTCGAAAGCCGCGAGGCCGGCGCGCTGAAGATGGTGCTGACGCCGGGGTG
A

Upstream 100 bases:

>100_bases
TGGGTCCCGGCTCTACCCCCGGCTTCCGCCGGGGTTCGGCCGGGATGACACGGAGAATGACCGTCGACGGAGCGTGTCCC
AGCCTTTTTGGAGCAATCTC

Downstream 100 bases:

>100_bases
GGCCTGTTCCCTCTCCCCTTGCGGGAGAGGGTGGCCCGAAGGGTCGGGTGAGGGGTCGCGCCGCGCTGTCCGGACAGGTC
TTTCAACCCCTCATCCGTCG

Product: zinc-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKALRYHGARDVRYESMDDPTPQSDRDAIVQVTACSICGSDLHIYHGHGFSEDLGFCVGHEAVGEVVEVGRGVQRLKVGD
KVMLPAAVGCGRCRSCLSGVIQTCENGQGACYGLSARLQGSQAEAVRVPAADMNAVPVPDGVSMDQALMMTDALATAWFG
ARNAEVRPGASVAVIGLGPIGLMAVESAYVMGAHVVYAIDPLPARRALAEEAGAIALHPDEALARVREDTKGRGLDCVIE
AVGGEATVDAALRLVRPRGVVSVIGVQQAKRFAFPLERAFGAGLTFRVGTCSVPEELPALFPLVRSGRLRPEKYISHRLP
LSDGPEAYRLFESREAGALKMVLTPG

Sequences:

>Translated_346_residues
MKALRYHGARDVRYESMDDPTPQSDRDAIVQVTACSICGSDLHIYHGHGFSEDLGFCVGHEAVGEVVEVGRGVQRLKVGD
KVMLPAAVGCGRCRSCLSGVIQTCENGQGACYGLSARLQGSQAEAVRVPAADMNAVPVPDGVSMDQALMMTDALATAWFG
ARNAEVRPGASVAVIGLGPIGLMAVESAYVMGAHVVYAIDPLPARRALAEEAGAIALHPDEALARVREDTKGRGLDCVIE
AVGGEATVDAALRLVRPRGVVSVIGVQQAKRFAFPLERAFGAGLTFRVGTCSVPEELPALFPLVRSGRLRPEKYISHRLP
LSDGPEAYRLFESREAGALKMVLTPG
>Mature_346_residues
MKALRYHGARDVRYESMDDPTPQSDRDAIVQVTACSICGSDLHIYHGHGFSEDLGFCVGHEAVGEVVEVGRGVQRLKVGD
KVMLPAAVGCGRCRSCLSGVIQTCENGQGACYGLSARLQGSQAEAVRVPAADMNAVPVPDGVSMDQALMMTDALATAWFG
ARNAEVRPGASVAVIGLGPIGLMAVESAYVMGAHVVYAIDPLPARRALAEEAGAIALHPDEALARVREDTKGRGLDCVIE
AVGGEATVDAALRLVRPRGVVSVIGVQQAKRFAFPLERAFGAGLTFRVGTCSVPEELPALFPLVRSGRLRPEKYISHRLP
LSDGPEAYRLFESREAGALKMVLTPG

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily [H]

Homologues:

Organism=Homo sapiens, GI71565152, Length=362, Percent_Identity=26.7955801104972, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI4501929, Length=336, Percent_Identity=27.0833333333333, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI156627571, Length=355, Percent_Identity=27.0422535211268, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI34577061, Length=347, Percent_Identity=27.0893371757925, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI4501939, Length=335, Percent_Identity=25.6716417910448, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI156523966, Length=335, Percent_Identity=25.3731343283582, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI71565154, Length=356, Percent_Identity=23.314606741573, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4501933, Length=347, Percent_Identity=26.2247838616715, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI71743840, Length=347, Percent_Identity=24.207492795389, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI262073058, Length=347, Percent_Identity=24.207492795389, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1786825, Length=389, Percent_Identity=37.2750642673522, Blast_Score=234, Evalue=9e-63,
Organism=Escherichia coli, GI87082125, Length=339, Percent_Identity=28.6135693215339, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788073, Length=341, Percent_Identity=27.2727272727273, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI226510992, Length=351, Percent_Identity=28.7749287749288, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1790045, Length=352, Percent_Identity=28.125, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788075, Length=359, Percent_Identity=26.4623955431755, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787863, Length=350, Percent_Identity=27.1428571428571, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790718, Length=336, Percent_Identity=25.5952380952381, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87081918, Length=334, Percent_Identity=28.7425149700599, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788407, Length=255, Percent_Identity=27.4509803921569, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786552, Length=349, Percent_Identity=25.7879656160458, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562876, Length=361, Percent_Identity=27.4238227146814, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17562878, Length=339, Percent_Identity=26.8436578171091, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71988145, Length=257, Percent_Identity=26.4591439688716, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562584, Length=268, Percent_Identity=26.865671641791, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319257, Length=390, Percent_Identity=27.4358974358974, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6319258, Length=387, Percent_Identity=27.390180878553, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323099, Length=335, Percent_Identity=25.6716417910448, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319955, Length=334, Percent_Identity=24.8502994011976, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322619, Length=334, Percent_Identity=24.8502994011976, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6320033, Length=363, Percent_Identity=25.8953168044077, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319621, Length=269, Percent_Identity=28.2527881040892, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=271, Percent_Identity=26.1992619926199, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323961, Length=263, Percent_Identity=26.615969581749, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324486, Length=271, Percent_Identity=26.1992619926199, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319949, Length=143, Percent_Identity=32.8671328671329, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323980, Length=129, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17137530, Length=348, Percent_Identity=28.735632183908, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17737897, Length=348, Percent_Identity=29.3103448275862, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17737895, Length=363, Percent_Identity=25.068870523416, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI45550770, Length=333, Percent_Identity=27.3273273273273, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI221457811, Length=333, Percent_Identity=27.3273273273273, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI45551930, Length=333, Percent_Identity=27.3273273273273, Blast_Score=88, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 36602; Mature: 36602

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALRYHGARDVRYESMDDPTPQSDRDAIVQVTACSICGSDLHIYHGHGFSEDLGFCVGH
CCCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEEEEECCCCEEEEECCCCCCCHHHHHCH
EAVGEVVEVGRGVQRLKVGDKVMLPAAVGCGRCRSCLSGVIQTCENGQGACYGLSARLQG
HHHHHHHHHCCCHHHHCCCCEEEECHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECC
SQAEAVRVPAADMNAVPVPDGVSMDQALMMTDALATAWFGARNAEVRPGASVAVIGLGPI
CCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCH
GLMAVESAYVMGAHVVYAIDPLPARRALAEEAGAIALHPDEALARVREDTKGRGLDCVIE
HHHHHHHHHHEEEEEEEEECCCCHHHHHHHHCCEEEECCHHHHHHHHHHCCCCCCEEEEE
AVGGEATVDAALRLVRPRGVVSVIGVQQAKRFAFPLERAFGAGLTFRVGTCSVPEELPAL
ECCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHCHHHHHHCCCCEEEECCCCCCHHHHHH
FPLVRSGRLRPEKYISHRLPLSDGPEAYRLFESREAGALKMVLTPG
HHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEECCC
>Mature Secondary Structure
MKALRYHGARDVRYESMDDPTPQSDRDAIVQVTACSICGSDLHIYHGHGFSEDLGFCVGH
CCCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEEEEECCCCEEEEECCCCCCCHHHHHCH
EAVGEVVEVGRGVQRLKVGDKVMLPAAVGCGRCRSCLSGVIQTCENGQGACYGLSARLQG
HHHHHHHHHCCCHHHHCCCCEEEECHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECC
SQAEAVRVPAADMNAVPVPDGVSMDQALMMTDALATAWFGARNAEVRPGASVAVIGLGPI
CCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCH
GLMAVESAYVMGAHVVYAIDPLPARRALAEEAGAIALHPDEALARVREDTKGRGLDCVIE
HHHHHHHHHHEEEEEEEEECCCCHHHHHHHHCCEEEECCHHHHHHHHHHCCCCCCEEEEE
AVGGEATVDAALRLVRPRGVVSVIGVQQAKRFAFPLERAFGAGLTFRVGTCSVPEELPAL
ECCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHCHHHHHHCCCCEEEECCCCCCHHHHHH
FPLVRSGRLRPEKYISHRLPLSDGPEAYRLFESREAGALKMVLTPG
HHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]