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The map label for this gene is pmbA [C]

Identifier: 16127056

GI number: 16127056

Start: 3047315

End: 3048640

Strand: Direct

Name: pmbA [C]

Synonym: CC_2824

Alternate gene names: 16127056

Gene position: 3047315-3048640 (Clockwise)

Preceding gene: 16127055

Following gene: 16127057

Centisome position: 75.86

GC content: 66.74

Gene sequence:

>1326_bases
ATGGGTATCATGACGGAAGCCGAGGCCAAGACGATCCTCGACAAGGTCCTCAAGCTCTCGACGGCGGACGAATGCACCGC
CCAGCTGACCGGCTCGATCGAAGGCAATATCCGCTTTGCGCTGAACAACGTCTCGACCAGCGGCGTGGTCAGCGACACCA
ATCTGGGCGTCTCGGTGGCCTTTGGTCGCCGGGTCGGCACGGCGTCGACCAACGACTTCTCCGACGCGTCCCTGGCCCGT
GCGGTCAAGCGCGCCGAGGAGCTGGCCCGCCTGGCGCCGGAGAACCCCGAGTTCGTGCCCGCGGTCGAAAAGCAGGTCTA
CAAGCCCAGCTCGACCTTCAGCGCGGCCACCGCGGCCATTACGCCTGAACAGCGCGCCGAGATCGCCATGGCCTCGATCG
CGCCCTGTCGCGCCAAGAACCTGATCGCGGCCGGGTTCCTGAACGACGAGCAGAGCTTCGTGGCCTTCGCCAACAGCAAG
GGCGCGTTCGGCTATCAGCGCTCGACCGACATGGACTACACCTGCACCGTGCGTACGGCCGATGGTCGCGGCTCGGGCTG
GGTCGCGCGCAGCCTGCAGGACTCCACCAGCTTCAAGCCGGCCAGCGACATCGAGATCGCCATGCGCAAGGCCAGCGCCT
CGGCCGAGGCCCAGGCTCTGGAGCCGGGCAAGTACACGGTGATCCTCGAGCCGGCCGCGGCCTCGGGCCTGATCTCGTTC
ATGTTCAACTTCTTCGACGCCCGCCAGGCGGACGAGGGCCGCAGCTTCCTGTCCAAGAAGGGCGGCGGCAACAAGCTGGG
CGAGCAGGTCTATGACCCGCGCGTGACCTTCATGTCCGACCCCTGGCACCCCGAGCTCGCCGTGCTGCCGTGGGACGCCA
CGGGCCGCGCCCGCGAGAAGATGGCCATGGTCGAGAACGGCAAGATCGCCAACCTGATCTACACCCCCTACTGGGCGCAG
AAGCAGGGCAAGCCGGTGGTCGGCCGTCCGGGCAACATCATCATGTCGGGCGGGACCAAGTCGACCGCCGACCTGGTGCG
CGAGACCGAGCGCGGCATCCTGGTGACCCGCACCTGGTACATCCGCATGGTCGATCCGCAGACCGTGCTGCTGACGGGCC
TGACCCGCGACGGCACCTTCTACATCGAGAACGGCCAGCTGAAGTATCCGCTGAAGAACTTCCGCTTCAACGAGTCGCCG
GTGATCATGCTCAACAACATCGACGAGCTGGGCCGCCCCGTGCGGGTCGGCGAAGGCATGCCGATGATGATCCCGCCGAT
GCGGGTGCGGGACTTCACCTTCACCTCGCTGTCGGACGCCGTCTGA

Upstream 100 bases:

>100_bases
TTCGGCCGTCAGCCACGGTTCGTCGACCACCCGGTTCGACGGCATCAACGTCATCAATACCGCGCGCTCGCTCGGTTAAG
CGGATCGAGGGAGACACATC

Downstream 100 bases:

>100_bases
CACACACCCATGGCCAGTCGTCGCGTAACCCGTTCGGAGTGTCTGCGTCTGCTGGCCGGTGGTGCGATGGGAGGTTGGCT
TGCCGGCCTCCCATCGGCCT

Product: TldD/PmbA family protein

Products: NA

Alternate protein names: PmbA Protein; TldD/PmbA Family Protein; Zn-Dependent Protease; CalR5 Protein; TldD Protein; Zinc-Dependent Protease; Zinc-Dependent Protease TldD/PmbA Family; Modulator Of DNA Gyrase; TldD/PmbA Family; Zn-Dependent Protease-Like Protein; Peptidase PmbA; TldE-Like Protein; LOW QUALITY PROTEIN CalR5 Protein; Inactivated Zn-Dependent Peptidase PMBA Ortholog; PmbA-Related Protein; Modulator Of DNA Gyrase Protein; DNA Gyrase Modulator Family Protein; Protease PmbA; Modulator Of DNA Gyrase Protein TldD; Microcin-Processing Peptidase PmbA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MGIMTEAEAKTILDKVLKLSTADECTAQLTGSIEGNIRFALNNVSTSGVVSDTNLGVSVAFGRRVGTASTNDFSDASLAR
AVKRAEELARLAPENPEFVPAVEKQVYKPSSTFSAATAAITPEQRAEIAMASIAPCRAKNLIAAGFLNDEQSFVAFANSK
GAFGYQRSTDMDYTCTVRTADGRGSGWVARSLQDSTSFKPASDIEIAMRKASASAEAQALEPGKYTVILEPAAASGLISF
MFNFFDARQADEGRSFLSKKGGGNKLGEQVYDPRVTFMSDPWHPELAVLPWDATGRAREKMAMVENGKIANLIYTPYWAQ
KQGKPVVGRPGNIIMSGGTKSTADLVRETERGILVTRTWYIRMVDPQTVLLTGLTRDGTFYIENGQLKYPLKNFRFNESP
VIMLNNIDELGRPVRVGEGMPMMIPPMRVRDFTFTSLSDAV

Sequences:

>Translated_441_residues
MGIMTEAEAKTILDKVLKLSTADECTAQLTGSIEGNIRFALNNVSTSGVVSDTNLGVSVAFGRRVGTASTNDFSDASLAR
AVKRAEELARLAPENPEFVPAVEKQVYKPSSTFSAATAAITPEQRAEIAMASIAPCRAKNLIAAGFLNDEQSFVAFANSK
GAFGYQRSTDMDYTCTVRTADGRGSGWVARSLQDSTSFKPASDIEIAMRKASASAEAQALEPGKYTVILEPAAASGLISF
MFNFFDARQADEGRSFLSKKGGGNKLGEQVYDPRVTFMSDPWHPELAVLPWDATGRAREKMAMVENGKIANLIYTPYWAQ
KQGKPVVGRPGNIIMSGGTKSTADLVRETERGILVTRTWYIRMVDPQTVLLTGLTRDGTFYIENGQLKYPLKNFRFNESP
VIMLNNIDELGRPVRVGEGMPMMIPPMRVRDFTFTSLSDAV
>Mature_440_residues
GIMTEAEAKTILDKVLKLSTADECTAQLTGSIEGNIRFALNNVSTSGVVSDTNLGVSVAFGRRVGTASTNDFSDASLARA
VKRAEELARLAPENPEFVPAVEKQVYKPSSTFSAATAAITPEQRAEIAMASIAPCRAKNLIAAGFLNDEQSFVAFANSKG
AFGYQRSTDMDYTCTVRTADGRGSGWVARSLQDSTSFKPASDIEIAMRKASASAEAQALEPGKYTVILEPAAASGLISFM
FNFFDARQADEGRSFLSKKGGGNKLGEQVYDPRVTFMSDPWHPELAVLPWDATGRAREKMAMVENGKIANLIYTPYWAQK
QGKPVVGRPGNIIMSGGTKSTADLVRETERGILVTRTWYIRMVDPQTVLLTGLTRDGTFYIENGQLKYPLKNFRFNESPV
IMLNNIDELGRPVRVGEGMPMMIPPMRVRDFTFTSLSDAV

Specific function: May Facilitate The Secretion Of The Peptide Antibiotic Microcin B17 (Mccb17) By Completing Its Maturation. Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 47985; Mature: 47854

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIMTEAEAKTILDKVLKLSTADECTAQLTGSIEGNIRFALNNVSTSGVVSDTNLGVSVA
CCCCCCHHHHHHHHHHHHCCCCHHHHHEEECCCCCEEEEEEECCCCCCEEECCCCCEEEE
FGRRVGTASTNDFSDASLARAVKRAEELARLAPENPEFVPAVEKQVYKPSSTFSAATAAI
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCEEEEC
TPEQRAEIAMASIAPCRAKNLIAAGFLNDEQSFVAFANSKGAFGYQRSTDMDYTCTVRTA
CCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEC
DGRGSGWVARSLQDSTSFKPASDIEIAMRKASASAEAQALEPGKYTVILEPAAASGLISF
CCCCCCEEEECCCCCCCCCCCCCHHHHHHHHCCCCCHHCCCCCCEEEEECCCHHHHHHHH
MFNFFDARQADEGRSFLSKKGGGNKLGEQVYDPRVTFMSDPWHPELAVLPWDATGRAREK
HHHHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCHHHH
MAMVENGKIANLIYTPYWAQKQGKPVVGRPGNIIMSGGTKSTADLVRETERGILVTRTWY
HHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCEEEEEEEE
IRMVDPQTVLLTGLTRDGTFYIENGQLKYPLKNFRFNESPVIMLNNIDELGRPVRVGEGM
EEEECCCEEEEEEECCCCEEEEECCEEECCHHHCCCCCCCEEEEECHHHHCCCEEECCCC
PMMIPPMRVRDFTFTSLSDAV
CEECCCCEECCEEECHHHCCC
>Mature Secondary Structure 
GIMTEAEAKTILDKVLKLSTADECTAQLTGSIEGNIRFALNNVSTSGVVSDTNLGVSVA
CCCCCHHHHHHHHHHHHCCCCHHHHHEEECCCCCEEEEEEECCCCCCEEECCCCCEEEE
FGRRVGTASTNDFSDASLARAVKRAEELARLAPENPEFVPAVEKQVYKPSSTFSAATAAI
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCEEEEC
TPEQRAEIAMASIAPCRAKNLIAAGFLNDEQSFVAFANSKGAFGYQRSTDMDYTCTVRTA
CCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEC
DGRGSGWVARSLQDSTSFKPASDIEIAMRKASASAEAQALEPGKYTVILEPAAASGLISF
CCCCCCEEEECCCCCCCCCCCCCHHHHHHHHCCCCCHHCCCCCCEEEEECCCHHHHHHHH
MFNFFDARQADEGRSFLSKKGGGNKLGEQVYDPRVTFMSDPWHPELAVLPWDATGRAREK
HHHHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCHHHH
MAMVENGKIANLIYTPYWAQKQGKPVVGRPGNIIMSGGTKSTADLVRETERGILVTRTWY
HHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCEEEEEEEE
IRMVDPQTVLLTGLTRDGTFYIENGQLKYPLKNFRFNESPVIMLNNIDELGRPVRVGEGM
EEEECCCEEEEEEECCCCEEEEECCEEECCHHHCCCCCCCEEEEECHHHHCCCEEECCCC
PMMIPPMRVRDFTFTSLSDAV
CEECCCCEECCEEECHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA