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The map label for this gene is czcC [H]

Identifier: 16126954

GI number: 16126954

Start: 2935081

End: 2936319

Strand: Direct

Name: czcC [H]

Synonym: CC_2721

Alternate gene names: 16126954

Gene position: 2935081-2936319 (Clockwise)

Preceding gene: 16126953

Following gene: 16126955

Centisome position: 73.07

GC content: 70.46

Gene sequence:

>1239_bases
ATGCCATCGTCATATGCCTGGCCCGTCGCCTTCGGCGCGGCTCTAGGCTTCATGAGCCTCGGCGCGCCCAGCGGCGCGGC
CGTCGCCCCGGTGACGCTCGCCCAAGCGCTGCAACGCGCCCAAGCGCAGTCACCGCTCATCAGCTCGGCCCAGGCGGCTC
TGGACGCCGCTCGGGGACGGGCGCGTCAGGCCGGTTTCTCGCCCAACCCTGAAGCCGGCCTTCAAAGTGAGAACATCGCC
GGTTCGGGACCCTATCAAGGGATCTCAAACGCTGAGACGACCTTCTCGCTCGGTCAACGACTCGAACTGGGCGGTAAGCG
CCGCACCCGCGTCGCAACCGCCCAAGCCGAGGTCGAGACCGCCGCCGTGCGGGCCGCCATCGCACGCGCCGACCTCACCC
AAGAGGTGAAGACCCGATATGCTCTGGCTCTTGAAGCCAAAGCCCGCGTCGCCGTGGCTCAGGAGGCCGCCGAGCGCGCG
CGGGATCTGGCCAGAGTGGCCGCCGCCCTGGTCGAGGCGGGCCGCGAGCCGCCGCTAAGGGCGTTGCGCGCCAGGACCGC
AAGCGACGAAGCTGAAGCCGCCGTCTTGGCCGCGCAGACCCTAGCTCTCGCCGCGAGACGCGCCCTGACCAGCCTTTGGG
GCGATCCGGATTTTGAGATCGAGCTCGTCGAGCCCTTGGCCGCCCCGACGCCACAGATGGCCGTCGATCCGAACATTTCC
CTGGACGTCCGACTGGCGCAAGCTGAGCGGGCCGCGGCCGAGGCGGCGATCGAGCGTGAACGCGCGGCGGGCGACCCCGA
CCTGACCATTCAGGCTGGGGTTCGCCGGTTCGAACAGACGGGCGACCGGGCGCTGATCGTCGGGTTCACCGCCCCTATTC
CGATCCGCGACCGAAACCAGGGCAATGTCGCCGCAGCGCGGGCTGACGCTAACGCCGCACAGGCGCGCGAGCGCCTGGCG
CTGACGGGCTCGATCCGCGCCATGCGTGACGCCCAGGCCTCGCTCAAGGCCGCTGAGGCCAGGCTCGAGGTGCTGTCCAG
CCGAACGGTTCCACAGGCTCAGCAAGCCGTGGACCTGGCGCGCCAGGGCTTTGAGGCTGGGAAGTTCTCCCTGCTCGACG
TGCTGGACGCCCAGGCGGCCCTATTGGCCTCCCGCAATGACCTCATCGCTGCGCGCCTGGAGCGCGCCCTGGCGCTGGCC
GCGCTCGAACGCGCCGCCGCGCAGGAGGACCGCTCATGA

Upstream 100 bases:

>100_bases
CGTCTTCGGCGCAGGGCCGCCTCGAAGAACCCCCTCGCGCCTGACCAGGCCGCGCTTTCGCGCGTGTTCGCCTCTGTCAG
AACGCAAGTAGGGATCTCCC

Downstream 100 bases:

>100_bases
TCAGAGCTCTTGATTGGAAAAAGCTGCTGGCCGCCTTGGCGATCAGCGGCCTGATCGCGGTGAGCGCCGCCGCCCTGATC
GGTCGCTCACGCCCGGCCCC

Product: metal ion efflux outer membrane factor protein family

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MPSSYAWPVAFGAALGFMSLGAPSGAAVAPVTLAQALQRAQAQSPLISSAQAALDAARGRARQAGFSPNPEAGLQSENIA
GSGPYQGISNAETTFSLGQRLELGGKRRTRVATAQAEVETAAVRAAIARADLTQEVKTRYALALEAKARVAVAQEAAERA
RDLARVAAALVEAGREPPLRALRARTASDEAEAAVLAAQTLALAARRALTSLWGDPDFEIELVEPLAAPTPQMAVDPNIS
LDVRLAQAERAAAEAAIERERAAGDPDLTIQAGVRRFEQTGDRALIVGFTAPIPIRDRNQGNVAAARADANAAQARERLA
LTGSIRAMRDAQASLKAAEARLEVLSSRTVPQAQQAVDLARQGFEAGKFSLLDVLDAQAALLASRNDLIAARLERALALA
ALERAAAQEDRS

Sequences:

>Translated_412_residues
MPSSYAWPVAFGAALGFMSLGAPSGAAVAPVTLAQALQRAQAQSPLISSAQAALDAARGRARQAGFSPNPEAGLQSENIA
GSGPYQGISNAETTFSLGQRLELGGKRRTRVATAQAEVETAAVRAAIARADLTQEVKTRYALALEAKARVAVAQEAAERA
RDLARVAAALVEAGREPPLRALRARTASDEAEAAVLAAQTLALAARRALTSLWGDPDFEIELVEPLAAPTPQMAVDPNIS
LDVRLAQAERAAAEAAIERERAAGDPDLTIQAGVRRFEQTGDRALIVGFTAPIPIRDRNQGNVAAARADANAAQARERLA
LTGSIRAMRDAQASLKAAEARLEVLSSRTVPQAQQAVDLARQGFEAGKFSLLDVLDAQAALLASRNDLIAARLERALALA
ALERAAAQEDRS
>Mature_411_residues
PSSYAWPVAFGAALGFMSLGAPSGAAVAPVTLAQALQRAQAQSPLISSAQAALDAARGRARQAGFSPNPEAGLQSENIAG
SGPYQGISNAETTFSLGQRLELGGKRRTRVATAQAEVETAAVRAAIARADLTQEVKTRYALALEAKARVAVAQEAAERAR
DLARVAAALVEAGREPPLRALRARTASDEAEAAVLAAQTLALAARRALTSLWGDPDFEIELVEPLAAPTPQMAVDPNISL
DVRLAQAERAAAEAAIERERAAGDPDLTIQAGVRRFEQTGDRALIVGFTAPIPIRDRNQGNVAAARADANAAQARERLAL
TGSIRAMRDAQASLKAAEARLEVLSSRTVPQAQQAVDLARQGFEAGKFSLLDVLDAQAALLASRNDLIAARLERALALAA
LERAAAQEDRS

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 43077; Mature: 42946

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSYAWPVAFGAALGFMSLGAPSGAAVAPVTLAQALQRAQAQSPLISSAQAALDAARGR
CCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ARQAGFSPNPEAGLQSENIAGSGPYQGISNAETTFSLGQRLELGGKRRTRVATAQAEVET
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AAVRAAIARADLTQEVKTRYALALEAKARVAVAQEAAERARDLARVAAALVEAGREPPLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ALRARTASDEAEAAVLAAQTLALAARRALTSLWGDPDFEIELVEPLAAPTPQMAVDPNIS
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEECCCCC
LDVRLAQAERAAAEAAIERERAAGDPDLTIQAGVRRFEQTGDRALIVGFTAPIPIRDRNQ
EEEEEHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCEEEEEEECCCCCCCCCC
GNVAAARADANAAQARERLALTGSIRAMRDAQASLKAAEARLEVLSSRTVPQAQQAVDLA
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RQGFEAGKFSLLDVLDAQAALLASRNDLIAARLERALALAALERAAAQEDRS
HCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PSSYAWPVAFGAALGFMSLGAPSGAAVAPVTLAQALQRAQAQSPLISSAQAALDAARGR
CCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ARQAGFSPNPEAGLQSENIAGSGPYQGISNAETTFSLGQRLELGGKRRTRVATAQAEVET
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AAVRAAIARADLTQEVKTRYALALEAKARVAVAQEAAERARDLARVAAALVEAGREPPLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ALRARTASDEAEAAVLAAQTLALAARRALTSLWGDPDFEIELVEPLAAPTPQMAVDPNIS
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEECCCCC
LDVRLAQAERAAAEAAIERERAAGDPDLTIQAGVRRFEQTGDRALIVGFTAPIPIRDRNQ
EEEEEHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCEEEEEEECCCCCCCCCC
GNVAAARADANAAQARERLALTGSIRAMRDAQASLKAAEARLEVLSSRTVPQAQQAVDLA
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RQGFEAGKFSLLDVLDAQAALLASRNDLIAARLERALALAALERAAAQEDRS
HCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]