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The map label for this gene is argK [C]

Identifier: 16126722

GI number: 16126722

Start: 2693283

End: 2694263

Strand: Direct

Name: argK [C]

Synonym: CC_2483

Alternate gene names: 16126722

Gene position: 2693283-2694263 (Clockwise)

Preceding gene: 16126721

Following gene: 16126724

Centisome position: 67.05

GC content: 71.15

Gene sequence:

>981_bases
GTGATCCCCGCGCTCGACATCGATAGCCTGGAACATCGCCTGGTCGCCGGCGACCGCGCGGCCCTGGCGCGCGCCATCAC
CCTGGTCGAGAGCCGTCGCGCCGATCACCAGGTCGCCGCGCGCACCCTGCTCTCGCGCCTGATGCCGCTGACCGGCCGCG
CCCAGCGAATCGGCATCACCGGGGTGCCGGGCGCGGGCAAGTCGACGACGATTGAGCGGTTCGGCTGCAATCTCGTCGAG
GCGGGCCACAGGGTGGCGGTGCTGGCCGTCGATCCCTCGTCCGGCCGCCACGGCGGGTCGATCCTGGGCGACAAGACCCG
GATGGAGCAGCTCAGCGTCCAGGCGAACGCCTTCATCCGCCCCTCCCCCTCGGGCGGCGCCCTGGGCGGGGTGGCGCGCA
AGACCCGCGAGGCGATGCTGCTGTGCGAGGCCGCCGGCTTCGACGTGGTGATCATCGAAACCGTGGGCGTGGGCCAGTCC
GAAACCGTCGTCGCCGACATGGTCGACATCTTCCTGGCGCTGCTCATTCCCGGCGGCGGCGATGAGCTGCAGGGCATCAA
GAAGGGCCTGATCGAGCTGGCTGACCTCCTGGTCATCAACAAGGCCGACGCCGATCCGGCCAAGGCCGAGCGCTCGGCAC
GCGACTATCGCAACGCCCTGCATATCCTCACCCCAGCCCATCCGGACTGGACGCCGCCGGTGCTGACCGCGTCCGGCCTG
ACCGGCCAGGGGTTGGATGTCCTGTGGACCCAGATCCTGCGCCATCGCGAAGTCATGACCGCCAACGGGGCCCGCGCCGC
TCGCCGCGCCGACCAGGACGCCCGCTGGATGTGGGCCATGGTCCGCGACCGCCTGGAAGACGCCTTCAAGACCGCCCCGG
CCGTGGCGGCGCTGGTTCCGGACCTCGAAACCGCCGTGCGTGAGGGCGAGGTTCCCGCATCGGCGGCGGCCGACAGGCTG
CTGGCGGCGTTTGGATTGTGA

Upstream 100 bases:

>100_bases
CAGAAGATCACTCGCGACTTCGTGGCGGCCTGAGGCGAGACCTTCCCTGGGGCGGCCTTGGGGCTTTCATCGCAGCCGGA
CAGGCTCTAAGCGGAAAGCC

Downstream 100 bases:

>100_bases
GGGCTACGCCCTCCCTTCACACAACGGGTAGGATTTCGCGCTGCGGCCGAAATGACACAGGAAATGCGAACGGCCTTCTC
TCCTCCCCCACCGGGGGAGG

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MIPALDIDSLEHRLVAGDRAALARAITLVESRRADHQVAARTLLSRLMPLTGRAQRIGITGVPGAGKSTTIERFGCNLVE
AGHRVAVLAVDPSSGRHGGSILGDKTRMEQLSVQANAFIRPSPSGGALGGVARKTREAMLLCEAAGFDVVIIETVGVGQS
ETVVADMVDIFLALLIPGGGDELQGIKKGLIELADLLVINKADADPAKAERSARDYRNALHILTPAHPDWTPPVLTASGL
TGQGLDVLWTQILRHREVMTANGARAARRADQDARWMWAMVRDRLEDAFKTAPAVAALVPDLETAVREGEVPASAAADRL
LAAFGL

Sequences:

>Translated_326_residues
MIPALDIDSLEHRLVAGDRAALARAITLVESRRADHQVAARTLLSRLMPLTGRAQRIGITGVPGAGKSTTIERFGCNLVE
AGHRVAVLAVDPSSGRHGGSILGDKTRMEQLSVQANAFIRPSPSGGALGGVARKTREAMLLCEAAGFDVVIIETVGVGQS
ETVVADMVDIFLALLIPGGGDELQGIKKGLIELADLLVINKADADPAKAERSARDYRNALHILTPAHPDWTPPVLTASGL
TGQGLDVLWTQILRHREVMTANGARAARRADQDARWMWAMVRDRLEDAFKTAPAVAALVPDLETAVREGEVPASAAADRL
LAAFGL
>Mature_326_residues
MIPALDIDSLEHRLVAGDRAALARAITLVESRRADHQVAARTLLSRLMPLTGRAQRIGITGVPGAGKSTTIERFGCNLVE
AGHRVAVLAVDPSSGRHGGSILGDKTRMEQLSVQANAFIRPSPSGGALGGVARKTREAMLLCEAAGFDVVIIETVGVGQS
ETVVADMVDIFLALLIPGGGDELQGIKKGLIELADLLVINKADADPAKAERSARDYRNALHILTPAHPDWTPPVLTASGL
TGQGLDVLWTQILRHREVMTANGARAARRADQDARWMWAMVRDRLEDAFKTAPAVAALVPDLETAVREGEVPASAAADRL
LAAFGL

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family

Homologues:

Organism=Homo sapiens, GI26892295, Length=330, Percent_Identity=47.8787878787879, Blast_Score=295, Evalue=5e-80,
Organism=Escherichia coli, GI1789285, Length=266, Percent_Identity=55.6390977443609, Blast_Score=281, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI71994271, Length=331, Percent_Identity=42.5981873111783, Blast_Score=263, Evalue=8e-71,
Organism=Caenorhabditis elegans, GI71994275, Length=271, Percent_Identity=44.6494464944649, Blast_Score=244, Evalue=4e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2483_CAUCR (P37895)

Other databases:

- EMBL:   M91449
- EMBL:   AE005673
- PIR:   B87557
- PIR:   S27534
- RefSeq:   NP_421286.1
- ProteinModelPortal:   P37895
- SMR:   P37895
- GeneID:   943968
- GenomeReviews:   AE005673_GR
- KEGG:   ccr:CC_2483
- NMPDR:   fig|190650.1.peg.2466
- TIGR:   CC_2483
- HOGENOM:   HBG728764
- OMA:   GVMELAD
- ProtClustDB:   PRK09435
- InterPro:   IPR005129
- InterPro:   IPR003593
- SMART:   SM00382
- TIGRFAMs:   TIGR00750

Pfam domain/function: PF03308 ArgK

EC number: 2.7.-.- [C]

Molecular weight: Translated: 34551; Mature: 34551

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: BINDING 203-203

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPALDIDSLEHRLVAGDRAALARAITLVESRRADHQVAARTLLSRLMPLTGRAQRIGIT
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEECEE
GVPGAGKSTTIERFGCNLVEAGHRVAVLAVDPSSGRHGGSILGDKTRMEQLSVQANAFIR
CCCCCCCCCHHHHHCCCHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCEEEC
PSPSGGALGGVARKTREAMLLCEAAGFDVVIIETVGVGQSETVVADMVDIFLALLIPGGG
CCCCCCCHHHHHHHHHHHHHEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCC
DELQGIKKGLIELADLLVINKADADPAKAERSARDYRNALHILTPAHPDWTPPVLTASGL
HHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEECCC
TGQGLDVLWTQILRHREVMTANGARAARRADQDARWMWAMVRDRLEDAFKTAPAVAALVP
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DLETAVREGEVPASAAADRLLAAFGL
CHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIPALDIDSLEHRLVAGDRAALARAITLVESRRADHQVAARTLLSRLMPLTGRAQRIGIT
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEECEE
GVPGAGKSTTIERFGCNLVEAGHRVAVLAVDPSSGRHGGSILGDKTRMEQLSVQANAFIR
CCCCCCCCCHHHHHCCCHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCEEEC
PSPSGGALGGVARKTREAMLLCEAAGFDVVIIETVGVGQSETVVADMVDIFLALLIPGGG
CCCCCCCHHHHHHHHHHHHHEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCC
DELQGIKKGLIELADLLVINKADADPAKAERSARDYRNALHILTPAHPDWTPPVLTASGL
HHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEECCC
TGQGLDVLWTQILRHREVMTANGARAARRADQDARWMWAMVRDRLEDAFKTAPAVAALVP
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DLETAVREGEVPASAAADRLLAAFGL
CHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647