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The map label for this gene is pepN

Identifier: 16126720

GI number: 16126720

Start: 2687928

End: 2690519

Strand: Direct

Name: pepN

Synonym: CC_2481

Alternate gene names: 16126720

Gene position: 2687928-2690519 (Clockwise)

Preceding gene: 16126719

Following gene: 16126721

Centisome position: 66.91

GC content: 67.55

Gene sequence:

>2592_bases
ATGCGCACCGACACGCCCCAAGCCGTGAACCTCGCGGACTATCGCCCGTTCCCGTTCGCCATCGAGACCACGCGACTGGT
CTTCGACCTGCACCCGACCCGGACACGCGTCAGCGCCGAGCTTTCGGTGCGCAGGACGGGCGGCAAGAACGAACCGCTCG
TGCTGAACGGCGAACGGCTGAAGCTGGTGTCGATCGCGATCGACGGCCGCCCGTTGGCTGCGGGCGAGTATGGTGTCGAT
GCGGAACGTCTCACGATCGCCGAGGCGCCCGACGCCTTTGTGCTGACGACCGAGGTCGAGATCGATCCGTCGTCGAACAA
GGCCCTGATGGGCCTCTACATGTCCGGCGGTCGCTTCTGCACCCAGTGCGAAGCCGAAGGGTTCCGCACCATCACCTATT
TCCCGGATCGTCCTGACGTGCTGTCGCGCTACAGCGTCCGGATCGAGGCCGACGGCAAGTTCCCGCACCTGCTGAGCAAC
GGCAATCCGGTGGCTTCGGGCTCGCTGGACGGCGGGCGGCACTTCGCCGAATGGTCCGACCCGTTCCCCAAGCCAAGCTA
TCTCTTCGCGCTGGTGGCCGGCGATCTCGACGTCCTGGCCGACAAGTTCATCACGATGAGCGGCCGCGAAGTCGCGTTGC
GGGTGTTCGTGGATCCCGGCCAGGCCTCGCGCGCGGCCTATGCGCTGGACAGCCTGAAACGCGCGATGAAATGGGACGAA
GAGGCGTTCGGTCGCGAATACGATCTGGATCTCTTCATGATCGTCGCCGTGCGCGACTTCAACTTCGGCGCCATGGAGAA
CAAGGGGCTGAACATCTTCAACAGCTCGCTGCTCCTGGCCGATCCCCAGACGGCGACCGACCTCGACTATGAGCGGATCG
AGGCCGTGGTCGCCCACGAATACTTCCACAACTGGACCGGCAACCGCATCACCTGCCGCGACTGGTTCCAGCTGTGCCTG
AAGGAAGGCTTCACCGTCTTCCGCGACCAGGGCTTAAGCGCCGACATGCGCGGCGCGGCCGTGCAGCGGATCAAGGATGT
CCGCGCCCTGCGCGCCCGCCAGTTCGCCGAGGACGCCGGTCCCCTCGCCCACCCCGTCCGTCCGTCCAGCTATCTGAAGA
TCGACAACTTCTACACCGCGACCATCTACGAGAAGGGCGCGGAGATCATCCGGATGCTGAAGGCCATCCTGGGCGCGCCA
GCGTTCCGGAAGGGCTGCGACCTCTACTTCCAGCGCCACGATGGCGAAGCGACCACGGTGGAGGCGTTCATCGCCTGCTT
CGCCGAGGCCTCCGGCCGCGACCTTTCGGGCTTCTTTGGCTGGTACGAGCAGGCCGGCACCCCGTCGGTCACCATCGAGA
CCGCCTATGACGCCGCCGCCGGCGCGCTGACCCTGACCCTGACCCAGAGCACGTCCCCGACGCCTGGCCAACCTGACAAG
AAGCCGCTGCCGATCCCGATCGCCATCGGCCTGCTGGCTGCGGACGGACGCGTTCTTCGCGACACCGAGATCGTGCTTCT
CGACCAGGCCCAGATGACGGTCCGTTGGGACAGCATCCCCGAGCCGCCGGTGCTGTCGGCGCTGCGCGGGTTCTCCGCGC
CGGTGAACCTGTCGACCGACGCCCGCCCGTCGGATCGCTACGTCCTGTTCGGGTCCGACACCGATCTCTTCAATCGCTGG
GAAGCCGGCCAGACCCTGGCGCGGGATCTGATCCTGACGCGTGCGGCCGGCGCACCCGATGAGGTGGGCGAGGAGCGCTA
CGCCGACGCCCTGGGCCGGGCGCTGGTCGATGACGCCGCCGAGCCGGCCTTCAAGGCCCTGTTGCTGGCGCTGCCCTCCG
AGCCCGACCTCGCCCTGATGTTCGAGGCCGCCGATCCCGCCGCCCTGCACGCGGCGCGTGACCATCTTCGCACGCGCATC
GCGGTGCACCTCGGCGACCTGTTGCGTCGCCTGCACGGCGAAATGCAGATCAACGGCGAGTTCTCCTCGGACGCGGCCGC
AGCCGGTCGTCGAGCGCTGCGCAACGCCTGCGCCGAAGCGCTGTCGGCCGACCCGCACGCCGAGAACCTCGCGCGCCTGC
TCGGCCATTTCGGCGCGGCCCGCAACATGACCGACATGATCGGCGGACTCTACCCGATGGTCGCCATGGGCGGCGTGCCG
CGTGAGAAGGCGCTCGAGAGCTTCCACCATGCCTGGCGGACCGAGCCTCTGGTGCTGGACAAGTGGTTCGCGGTGCAGGG
CCGCGATCCGAACCCCGATGCGCTGGAACGCGTAATCGCCCTGACCCAGCACCCGGATTTCGAGCCCACCAACCCCAATC
GGTTGCGCGCGCTGGTCTCGACCTTCGCCAACTTCAACCCGGCGCGGTTCCACGACCCCAGCGGCGCGGGCTATGCGTTC
CTGGCGGACGAGATCCTCAAGGTCGACGCCTTCAACCCGATGACGGCGGCGCGACTGGTCGAGCCTCTGGGCGGGTGGCG
TCGTTACAAGCCCGAACTGGGCGACCTGATGCGCGCCCAGCTGGAACGCATCGTGGCCCACCCCAACCTCTCCAAGAACG
TCCTGGAACTGGCCAGCAAGGCGCTCGGCTGA

Upstream 100 bases:

>100_bases
CCTCCGGCGACTAGGCCGTGTCCTGACGCGTCACCATTAATTCGATCCGGGTCGTCAAGGTCCCCTCGCGGACCTCGATG
AGCGGGATTAAGTAGGACGA

Downstream 100 bases:

>100_bases
CGAGTCTTTTGCGATGGTCGGCCACTCGGGATTGCGACCAATAGGCTCAACCGTTCGAAATCCGCCGCTTCGGCGGTGAC
GCGAACGGCGGCGGTACGTT

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase

Number of amino acids: Translated: 863; Mature: 863

Protein sequence:

>863_residues
MRTDTPQAVNLADYRPFPFAIETTRLVFDLHPTRTRVSAELSVRRTGGKNEPLVLNGERLKLVSIAIDGRPLAAGEYGVD
AERLTIAEAPDAFVLTTEVEIDPSSNKALMGLYMSGGRFCTQCEAEGFRTITYFPDRPDVLSRYSVRIEADGKFPHLLSN
GNPVASGSLDGGRHFAEWSDPFPKPSYLFALVAGDLDVLADKFITMSGREVALRVFVDPGQASRAAYALDSLKRAMKWDE
EAFGREYDLDLFMIVAVRDFNFGAMENKGLNIFNSSLLLADPQTATDLDYERIEAVVAHEYFHNWTGNRITCRDWFQLCL
KEGFTVFRDQGLSADMRGAAVQRIKDVRALRARQFAEDAGPLAHPVRPSSYLKIDNFYTATIYEKGAEIIRMLKAILGAP
AFRKGCDLYFQRHDGEATTVEAFIACFAEASGRDLSGFFGWYEQAGTPSVTIETAYDAAAGALTLTLTQSTSPTPGQPDK
KPLPIPIAIGLLAADGRVLRDTEIVLLDQAQMTVRWDSIPEPPVLSALRGFSAPVNLSTDARPSDRYVLFGSDTDLFNRW
EAGQTLARDLILTRAAGAPDEVGEERYADALGRALVDDAAEPAFKALLLALPSEPDLALMFEAADPAALHAARDHLRTRI
AVHLGDLLRRLHGEMQINGEFSSDAAAAGRRALRNACAEALSADPHAENLARLLGHFGAARNMTDMIGGLYPMVAMGGVP
REKALESFHHAWRTEPLVLDKWFAVQGRDPNPDALERVIALTQHPDFEPTNPNRLRALVSTFANFNPARFHDPSGAGYAF
LADEILKVDAFNPMTAARLVEPLGGWRRYKPELGDLMRAQLERIVAHPNLSKNVLELASKALG

Sequences:

>Translated_863_residues
MRTDTPQAVNLADYRPFPFAIETTRLVFDLHPTRTRVSAELSVRRTGGKNEPLVLNGERLKLVSIAIDGRPLAAGEYGVD
AERLTIAEAPDAFVLTTEVEIDPSSNKALMGLYMSGGRFCTQCEAEGFRTITYFPDRPDVLSRYSVRIEADGKFPHLLSN
GNPVASGSLDGGRHFAEWSDPFPKPSYLFALVAGDLDVLADKFITMSGREVALRVFVDPGQASRAAYALDSLKRAMKWDE
EAFGREYDLDLFMIVAVRDFNFGAMENKGLNIFNSSLLLADPQTATDLDYERIEAVVAHEYFHNWTGNRITCRDWFQLCL
KEGFTVFRDQGLSADMRGAAVQRIKDVRALRARQFAEDAGPLAHPVRPSSYLKIDNFYTATIYEKGAEIIRMLKAILGAP
AFRKGCDLYFQRHDGEATTVEAFIACFAEASGRDLSGFFGWYEQAGTPSVTIETAYDAAAGALTLTLTQSTSPTPGQPDK
KPLPIPIAIGLLAADGRVLRDTEIVLLDQAQMTVRWDSIPEPPVLSALRGFSAPVNLSTDARPSDRYVLFGSDTDLFNRW
EAGQTLARDLILTRAAGAPDEVGEERYADALGRALVDDAAEPAFKALLLALPSEPDLALMFEAADPAALHAARDHLRTRI
AVHLGDLLRRLHGEMQINGEFSSDAAAAGRRALRNACAEALSADPHAENLARLLGHFGAARNMTDMIGGLYPMVAMGGVP
REKALESFHHAWRTEPLVLDKWFAVQGRDPNPDALERVIALTQHPDFEPTNPNRLRALVSTFANFNPARFHDPSGAGYAF
LADEILKVDAFNPMTAARLVEPLGGWRRYKPELGDLMRAQLERIVAHPNLSKNVLELASKALG
>Mature_863_residues
MRTDTPQAVNLADYRPFPFAIETTRLVFDLHPTRTRVSAELSVRRTGGKNEPLVLNGERLKLVSIAIDGRPLAAGEYGVD
AERLTIAEAPDAFVLTTEVEIDPSSNKALMGLYMSGGRFCTQCEAEGFRTITYFPDRPDVLSRYSVRIEADGKFPHLLSN
GNPVASGSLDGGRHFAEWSDPFPKPSYLFALVAGDLDVLADKFITMSGREVALRVFVDPGQASRAAYALDSLKRAMKWDE
EAFGREYDLDLFMIVAVRDFNFGAMENKGLNIFNSSLLLADPQTATDLDYERIEAVVAHEYFHNWTGNRITCRDWFQLCL
KEGFTVFRDQGLSADMRGAAVQRIKDVRALRARQFAEDAGPLAHPVRPSSYLKIDNFYTATIYEKGAEIIRMLKAILGAP
AFRKGCDLYFQRHDGEATTVEAFIACFAEASGRDLSGFFGWYEQAGTPSVTIETAYDAAAGALTLTLTQSTSPTPGQPDK
KPLPIPIAIGLLAADGRVLRDTEIVLLDQAQMTVRWDSIPEPPVLSALRGFSAPVNLSTDARPSDRYVLFGSDTDLFNRW
EAGQTLARDLILTRAAGAPDEVGEERYADALGRALVDDAAEPAFKALLLALPSEPDLALMFEAADPAALHAARDHLRTRI
AVHLGDLLRRLHGEMQINGEFSSDAAAAGRRALRNACAEALSADPHAENLARLLGHFGAARNMTDMIGGLYPMVAMGGVP
REKALESFHHAWRTEPLVLDKWFAVQGRDPNPDALERVIALTQHPDFEPTNPNRLRALVSTFANFNPARFHDPSGAGYAF
LADEILKVDAFNPMTAARLVEPLGGWRRYKPELGDLMRAQLERIVAHPNLSKNVLELASKALG

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cytoplasm, Bound To The Inner Face Of The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family

Homologues:

Organism=Homo sapiens, GI132814467, Length=332, Percent_Identity=28.3132530120482, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI61742777, Length=327, Percent_Identity=27.5229357798165, Blast_Score=123, Evalue=6e-28,
Organism=Homo sapiens, GI61742775, Length=327, Percent_Identity=27.5229357798165, Blast_Score=123, Evalue=6e-28,
Organism=Homo sapiens, GI158937236, Length=280, Percent_Identity=28.5714285714286, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI194306629, Length=286, Percent_Identity=27.972027972028, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI11641261, Length=286, Percent_Identity=27.972027972028, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI94818901, Length=294, Percent_Identity=30.6122448979592, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI94818891, Length=294, Percent_Identity=30.6122448979592, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI310123622, Length=246, Percent_Identity=28.8617886178862, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI157266300, Length=293, Percent_Identity=29.0102389078498, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI310133497, Length=246, Percent_Identity=29.2682926829268, Blast_Score=101, Evalue=4e-21,
Organism=Homo sapiens, GI4505029, Length=400, Percent_Identity=26, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI7019561, Length=261, Percent_Identity=27.5862068965517, Blast_Score=87, Evalue=8e-17,
Organism=Homo sapiens, GI194239713, Length=235, Percent_Identity=28.0851063829787, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI40316915, Length=275, Percent_Identity=30.9090909090909, Blast_Score=73, Evalue=9e-13,
Organism=Escherichia coli, GI1787163, Length=876, Percent_Identity=46.1187214611872, Blast_Score=737, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71989076, Length=374, Percent_Identity=29.6791443850267, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71989071, Length=374, Percent_Identity=29.6791443850267, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17569225, Length=463, Percent_Identity=25.7019438444924, Blast_Score=105, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17569221, Length=317, Percent_Identity=28.391167192429, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71984353, Length=431, Percent_Identity=26.4501160092807, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI115533276, Length=238, Percent_Identity=28.1512605042017, Blast_Score=100, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71984339, Length=432, Percent_Identity=26.3888888888889, Blast_Score=100, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI115533278, Length=238, Percent_Identity=28.1512605042017, Blast_Score=99, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI193206928, Length=416, Percent_Identity=25.9615384615385, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193206926, Length=416, Percent_Identity=25.9615384615385, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI133903840, Length=418, Percent_Identity=25.8373205741627, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17565628, Length=392, Percent_Identity=26.0204081632653, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17544504, Length=219, Percent_Identity=27.3972602739726, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71990873, Length=160, Percent_Identity=30.625, Blast_Score=75, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI9755335, Length=391, Percent_Identity=25.0639386189258, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6321837, Length=388, Percent_Identity=26.5463917525773, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6322054, Length=412, Percent_Identity=21.6019417475728, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24646514, Length=458, Percent_Identity=29.0393013100437, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24646516, Length=336, Percent_Identity=31.547619047619, Blast_Score=149, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24646518, Length=336, Percent_Identity=31.547619047619, Blast_Score=149, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24655257, Length=372, Percent_Identity=28.7634408602151, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24655252, Length=372, Percent_Identity=28.7634408602151, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24655274, Length=372, Percent_Identity=28.7634408602151, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24655260, Length=372, Percent_Identity=28.7634408602151, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24655265, Length=372, Percent_Identity=28.7634408602151, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24655268, Length=372, Percent_Identity=28.7634408602151, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24651025, Length=303, Percent_Identity=24.7524752475248, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24651023, Length=303, Percent_Identity=24.7524752475248, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24651021, Length=303, Percent_Identity=24.7524752475248, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24651016, Length=241, Percent_Identity=28.6307053941909, Blast_Score=103, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24646512, Length=452, Percent_Identity=24.5575221238938, Blast_Score=103, Evalue=8e-22,
Organism=Drosophila melanogaster, GI221379089, Length=405, Percent_Identity=26.4197530864197, Blast_Score=102, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24646510, Length=452, Percent_Identity=24.5575221238938, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21358341, Length=310, Percent_Identity=27.741935483871, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI45550850, Length=292, Percent_Identity=28.7671232876712, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24650973, Length=292, Percent_Identity=28.7671232876712, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI161078673, Length=381, Percent_Identity=29.1338582677165, Blast_Score=98, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28571901, Length=381, Percent_Identity=29.1338582677165, Blast_Score=98, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24648786, Length=402, Percent_Identity=25.3731343283582, Blast_Score=89, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24648790, Length=310, Percent_Identity=23.8709677419355, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571792, Length=409, Percent_Identity=24.9388753056235, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24585062, Length=411, Percent_Identity=24.0875912408759, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24585064, Length=411, Percent_Identity=24.0875912408759, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24585066, Length=411, Percent_Identity=24.0875912408759, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45550350, Length=411, Percent_Identity=24.0875912408759, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221330574, Length=506, Percent_Identity=22.3320158102767, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AMPN_CAUCR (P37893)

Other databases:

- EMBL:   AE005673
- EMBL:   M91449
- PIR:   H87556
- PIR:   S27532
- RefSeq:   NP_421284.1
- ProteinModelPortal:   P37893
- SMR:   P37893
- MEROPS:   M01.005
- GeneID:   944052
- GenomeReviews:   AE005673_GR
- KEGG:   ccr:CC_2481
- NMPDR:   fig|190650.1.peg.2464
- TIGR:   CC_2481
- HOGENOM:   HBG289207
- OMA:   DIFMIVA
- ProtClustDB:   PRK14015
- BRENDA:   3.4.11.2
- GO:   GO:0006508
- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779
- PANTHER:   PTHR11533:SF8
- PANTHER:   PTHR11533
- PRINTS:   PR00756
- TIGRFAMs:   TIGR02414

Pfam domain/function: PF01433 Peptidase_M1

EC number: =3.4.11.2

Molecular weight: Translated: 94881; Mature: 94881

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 300-300 ACT_SITE 383-383

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTDTPQAVNLADYRPFPFAIETTRLVFDLHPTRTRVSAELSVRRTGGKNEPLVLNGERL
CCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCEEEEEEEEEECCCCCCCEEECCCEE
KLVSIAIDGRPLAAGEYGVDAERLTIAEAPDAFVLTTEVEIDPSSNKALMGLYMSGGRFC
EEEEEEECCCEECCCCCCCCHHHEEEECCCCEEEEEEEEEECCCCCCEEEEEEECCCCEE
TQCEAEGFRTITYFPDRPDVLSRYSVRIEADGKFPHLLSNGNPVASGSLDGGRHFAEWSD
EEECCCCCEEEEECCCCCCCCCEEEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCCCCCC
PFPKPSYLFALVAGDLDVLADKFITMSGREVALRVFVDPGQASRAAYALDSLKRAMKWDE
CCCCCCEEEEEHHCCHHHHHHHHEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCH
EAFGREYDLDLFMIVAVRDFNFGAMENKGLNIFNSSLLLADPQTATDLDYERIEAVVAHE
HHCCCCCCCCEEEEEEEEECCCCCCCCCCCEEECCEEEEECCCCCCCCCHHHHHHHHHHH
YFHNWTGNRITCRDWFQLCLKEGFTVFRDQGLSADMRGAAVQRIKDVRALRARQFAEDAG
HHHCCCCCEEEHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PLAHPVRPSSYLKIDNFYTATIYEKGAEIIRMLKAILGAPAFRKGCDLYFQRHDGEATTV
CCCCCCCCCCEEEECCEEEEHHHHHHHHHHHHHHHHHCCCCHHCCCCEEEEECCCCHHHH
EAFIACFAEASGRDLSGFFGWYEQAGTPSVTIETAYDAAAGALTLTLTQSTSPTPGQPDK
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCC
KPLPIPIAIGLLAADGRVLRDTEIVLLDQAQMTVRWDSIPEPPVLSALRGFSAPVNLSTD
CCCCCEEEEEEEECCCEEEECCEEEEEECCEEEEEECCCCCCHHHHHHHCCCCCCCCCCC
ARPSDRYVLFGSDTDLFNRWEAGQTLARDLILTRAAGAPDEVGEERYADALGRALVDDAA
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
EPAFKALLLALPSEPDLALMFEAADPAALHAARDHLRTRIAVHLGDLLRRLHGEMQINGE
CHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
FSSDAAAAGRRALRNACAEALSADPHAENLARLLGHFGAARNMTDMIGGLYPMVAMGGVP
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
REKALESFHHAWRTEPLVLDKWFAVQGRDPNPDALERVIALTQHPDFEPTNPNRLRALVS
HHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
TFANFNPARFHDPSGAGYAFLADEILKVDAFNPMTAARLVEPLGGWRRYKPELGDLMRAQ
HHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHCCCHHHHHHHHH
LERIVAHPNLSKNVLELASKALG
HHHHHCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRTDTPQAVNLADYRPFPFAIETTRLVFDLHPTRTRVSAELSVRRTGGKNEPLVLNGERL
CCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCEEEEEEEEEECCCCCCCEEECCCEE
KLVSIAIDGRPLAAGEYGVDAERLTIAEAPDAFVLTTEVEIDPSSNKALMGLYMSGGRFC
EEEEEEECCCEECCCCCCCCHHHEEEECCCCEEEEEEEEEECCCCCCEEEEEEECCCCEE
TQCEAEGFRTITYFPDRPDVLSRYSVRIEADGKFPHLLSNGNPVASGSLDGGRHFAEWSD
EEECCCCCEEEEECCCCCCCCCEEEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCCCCCC
PFPKPSYLFALVAGDLDVLADKFITMSGREVALRVFVDPGQASRAAYALDSLKRAMKWDE
CCCCCCEEEEEHHCCHHHHHHHHEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCH
EAFGREYDLDLFMIVAVRDFNFGAMENKGLNIFNSSLLLADPQTATDLDYERIEAVVAHE
HHCCCCCCCCEEEEEEEEECCCCCCCCCCCEEECCEEEEECCCCCCCCCHHHHHHHHHHH
YFHNWTGNRITCRDWFQLCLKEGFTVFRDQGLSADMRGAAVQRIKDVRALRARQFAEDAG
HHHCCCCCEEEHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PLAHPVRPSSYLKIDNFYTATIYEKGAEIIRMLKAILGAPAFRKGCDLYFQRHDGEATTV
CCCCCCCCCCEEEECCEEEEHHHHHHHHHHHHHHHHHCCCCHHCCCCEEEEECCCCHHHH
EAFIACFAEASGRDLSGFFGWYEQAGTPSVTIETAYDAAAGALTLTLTQSTSPTPGQPDK
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCC
KPLPIPIAIGLLAADGRVLRDTEIVLLDQAQMTVRWDSIPEPPVLSALRGFSAPVNLSTD
CCCCCEEEEEEEECCCEEEECCEEEEEECCEEEEEECCCCCCHHHHHHHCCCCCCCCCCC
ARPSDRYVLFGSDTDLFNRWEAGQTLARDLILTRAAGAPDEVGEERYADALGRALVDDAA
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
EPAFKALLLALPSEPDLALMFEAADPAALHAARDHLRTRIAVHLGDLLRRLHGEMQINGE
CHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
FSSDAAAAGRRALRNACAEALSADPHAENLARLLGHFGAARNMTDMIGGLYPMVAMGGVP
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
REKALESFHHAWRTEPLVLDKWFAVQGRDPNPDALERVIALTQHPDFEPTNPNRLRALVS
HHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
TFANFNPARFHDPSGAGYAFLADEILKVDAFNPMTAARLVEPLGGWRRYKPELGDLMRAQ
HHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHCCCHHHHHHHHH
LERIVAHPNLSKNVLELASKALG
HHHHHCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647; 8421698