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The map label for this gene is lpsI [H]

Identifier: 16126644

GI number: 16126644

Start: 2610415

End: 2611140

Strand: Direct

Name: lpsI [H]

Synonym: CC_2405

Alternate gene names: 16126644

Gene position: 2610415-2611140 (Clockwise)

Preceding gene: 16126643

Following gene: 16126645

Centisome position: 64.99

GC content: 63.22

Gene sequence:

>726_bases
ATGAAAAGCAAGATCTACGAGAGCGCGGCCGCGGCCTTGGAGGGCGTCGTTTTCGACGGCATGACCCTGATGTCCGGGGG
CTTTGGCCTGTCGGGCAATCCCGAGACCCTGATCCCGGCCCTCAAGGATACGGGCGTCAAGGCCCTAACGGTGATCAGCA
ACAACTGCGGCGCTGACGGCTTCGGCCTCTGGATGCTGCTAAACAACGGCCAGATCCGGAAGATGGTCTCGTCCTATGTC
GGCGAGAATAAGCTGTTCGAACAGCTCTATCTGTCGGGCGAGCTGGAGCTGGAGCTGAACCCGCAGGGCACCTTGGCCGA
GCGCATTCGCGCCGGCGGCGCCGGCATCCCAGCCTTCTACACCAAGACCGGCGTTGGCACGGTGGTGGCCGAGGGCAAGC
CGGTAGAGACCTTCGAGGGCGAGCCCTATCTCCGCGAGACCTGGCTGCGCGCCGACCTCTCCATCGTCAAGGCCTGGAAA
GCCGACCCGGAAGGCAACCTGGTGTTCCGGATGACGGCCCGCAATTTCAATCCCGTCATGGCCACGGCCGGCAAGGTCAC
CATCGTCGAGGTCGAGGAGATCGTCGAGGCCGGCGAGCTGGACGCCAACGCGATCCACACGCCCGGCATCTATGTCGACC
GCATCGTCAAGTCGACGATCAATGAAAAGCGCATCGAGAAGCTGACCACCCGCCCACGAGAGATCCACGCTGGGGAGACC
GTATAA

Upstream 100 bases:

>100_bases
CGCCGAACTCGCCTACATCAAGGGCTCGCGCGCCGCTCAGGTGACGCTGGCCGAGAACTATGTCGGCCTTCCCCTGGTCT
AGAAGGCTGTGGAGCGTCCC

Downstream 100 bases:

>100_bases
TGGCCTGGACCCGCGACGAGATGGCGGCTCGCGCCGCCCGCGAGCTGAAGAACGGCTTCTACGTCAACCTCGGCATCGGC
ATCCCGACCCTGGTCGCCAA

Product: 3-oxoadipate CoA-transferase subunit alpha

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MKSKIYESAAAALEGVVFDGMTLMSGGFGLSGNPETLIPALKDTGVKALTVISNNCGADGFGLWMLLNNGQIRKMVSSYV
GENKLFEQLYLSGELELELNPQGTLAERIRAGGAGIPAFYTKTGVGTVVAEGKPVETFEGEPYLRETWLRADLSIVKAWK
ADPEGNLVFRMTARNFNPVMATAGKVTIVEVEEIVEAGELDANAIHTPGIYVDRIVKSTINEKRIEKLTTRPREIHAGET
V

Sequences:

>Translated_241_residues
MKSKIYESAAAALEGVVFDGMTLMSGGFGLSGNPETLIPALKDTGVKALTVISNNCGADGFGLWMLLNNGQIRKMVSSYV
GENKLFEQLYLSGELELELNPQGTLAERIRAGGAGIPAFYTKTGVGTVVAEGKPVETFEGEPYLRETWLRADLSIVKAWK
ADPEGNLVFRMTARNFNPVMATAGKVTIVEVEEIVEAGELDANAIHTPGIYVDRIVKSTINEKRIEKLTTRPREIHAGET
V
>Mature_241_residues
MKSKIYESAAAALEGVVFDGMTLMSGGFGLSGNPETLIPALKDTGVKALTVISNNCGADGFGLWMLLNNGQIRKMVSSYV
GENKLFEQLYLSGELELELNPQGTLAERIRAGGAGIPAFYTKTGVGTVVAEGKPVETFEGEPYLRETWLRADLSIVKAWK
ADPEGNLVFRMTARNFNPVMATAGKVTIVEVEEIVEAGELDANAIHTPGIYVDRIVKSTINEKRIEKLTTRPREIHAGET
V

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=247, Percent_Identity=53.4412955465587, Blast_Score=248, Evalue=4e-66,
Organism=Homo sapiens, GI11545841, Length=247, Percent_Identity=53.0364372469636, Blast_Score=228, Evalue=5e-60,
Organism=Escherichia coli, GI1788551, Length=218, Percent_Identity=45.4128440366972, Blast_Score=189, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17531517, Length=258, Percent_Identity=48.8372093023256, Blast_Score=224, Evalue=4e-59,
Organism=Drosophila melanogaster, GI21358325, Length=250, Percent_Identity=51.2, Blast_Score=232, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24655794, Length=250, Percent_Identity=51.2, Blast_Score=231, Evalue=3e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 26078; Mature: 26078

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKIYESAAAALEGVVFDGMTLMSGGFGLSGNPETLIPALKDTGVKALTVISNNCGADG
CCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCC
FGLWMLLNNGQIRKMVSSYVGENKLFEQLYLSGELELELNPQGTLAERIRAGGAGIPAFY
EEEEEEECCCHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCEE
TKTGVGTVVAEGKPVETFEGEPYLRETWLRADLSIVKAWKADPEGNLVFRMTARNFNPVM
ECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEE
ATAGKVTIVEVEEIVEAGELDANAIHTPGIYVDRIVKSTINEKRIEKLTTRPREIHAGET
ECCCCEEEEEHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
V
C
>Mature Secondary Structure
MKSKIYESAAAALEGVVFDGMTLMSGGFGLSGNPETLIPALKDTGVKALTVISNNCGADG
CCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCC
FGLWMLLNNGQIRKMVSSYVGENKLFEQLYLSGELELELNPQGTLAERIRAGGAGIPAFY
EEEEEEECCCHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCEE
TKTGVGTVVAEGKPVETFEGEPYLRETWLRADLSIVKAWKADPEGNLVFRMTARNFNPVM
ECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEE
ATAGKVTIVEVEEIVEAGELDANAIHTPGIYVDRIVKSTINEKRIEKLTTRPREIHAGET
ECCCCEEEEEHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]